Aetiology and clinical spectrum of acute undifferentiated febrile illness in hospitalized children
Pediatric Review International Journal of Pediatric Research
Introduction:Acute fever of 2 weeks duration with non-specific signs and symptoms is known as acute undifferentiated febrile illness (AUFI). Owing to non-specific presentation, it remains a diagnostic challenge. Hence the present study focuses on etiology and clinical profile of undifferentiated febrile illness. Methodology: All children aged 2-12 years admitted with fever of 5-15 days duration, for which no cause was found after a thorough history and clinical examination were included from
... re included from July 2015 to June 2016 prospectively. History, examination findings, investigations and the treatment details were recorded. Data analyzed using SSPS software. Results: Total sample size was 263. The mean age was 6.7 ± 3.4 years. Most common symptoms were cough and vomiting. The most common diagnosis arrived at was Scrub typhus (22.4%) followed by Dengue (11%), Enteric fever (11%), Co-infections (6.1%), Urinary tract infections (3%) and Lower respiratory tract infections (2.3%). Fever was still undiagnosed in 116 children (44.1%). No malarial infection was noted. Conclusion: Non-malarial infections are common in this part of the country in children with AUFI. regions, common causes are Dengue, Enteric fever, Scrub typhus, Leptospirosis, and Malaria in varying proportions which are potentially treatable [4, 5] . Several studies are available on AUFI in adults    whereas data are limited in children. There is thus an urgent need to describe the demography, clinical profile, and identification of etiology in children seeking health care facility for AUFI. Hence the present study will focus on etiology and clinical profile of undifferentiated febrile illness.