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Results of in Vivo and in Vitro Studies for Assessing Prenatal Toxicity

Diether Neubert, Gudrun Blankenburg, Ibrahim Chahoud, Gabriele Franz, Rainer Herken, Michael Kastner, Stephan Klug, Joachim Kroger, Ralf Krowke, Constanze Lewandowski, Hans-Joachim Merker, Thomas Schulz (+1 others)
1986 Environmental Health Perspectives  
Examples of a combined approach using in vivo as well as in vitro methods for the assessment of prenatal toxicity are presented. The topics discussed include the analysis of the possible embryotoxic potential of valproic acid (VPA), female sex hormones, bis(tri-n-butyltin) oxide (TBTO), and acyclovir and the problem of supplementing in vitro systems with drug-metabolizing activity.
doi:10.2307/3430346 fatcat:7exbejwv3fgt5ptwssxd57bqt4