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Pathophysiology of Asthma

Younus Ahmad Bhat
2017 International Journal for Research in Applied Science and Engineering Technology  
Asthma is a complex disorder causing the narrowing of the lung airways and affects people of all ages but is most prevalent during childhood. The main symptoms involved are wheezing, chest tightness, coughing and shortness of breath. Many cells which include eosinophils, lymphocytes, and mast cells are involved in the pathogenesis of asthma. The present drugs that are used to alleviate asthma symptoms are steroidal that has many side effects. In order to develop most effective and nonsteroidal
more » ... e and nonsteroidal drugs the path physiology need to be explored at biochemical level. The lipoxygenases and their metabolites could be a potential target for the development of new drugs for the treatment of asthma. In this review, we highlight the various path physiological pathways involved in asthma, which could pave for the discovery of novel drugs.
doi:10.22214/ijraset.2017.11135 fatcat:kxdzihq6yzg5lia4uc3wqg7mt4