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Rapid Fire Abstract Session: News on Hemodynamics and Outcomes in Patients Undergoing Valve Procedure and Assist Device Implantation

SSCSSCS Annual Meeting
2019 Cardiovascular Medicine  
Recently, a staging classification of cardiac damage in aortic stenosis (AS) based on echocardiographic measurements has been shown to provide prognostic information after aortic valve replacement (AVR; Généreux P et al. Eur Heart J 2017). We aimed to validate this principle by creation of an analogous five stage classification based on invasive hemodynamics. Methods: We studied 422 patients (age 75±10 years, 59% males) with severe AS [indexed aortic valve area (iAVA) 0.41±0.13 cm 2 /m 2 ]
more » ... 13 cm 2 /m 2 ] undergoing AVR with complete pre-AVR invasive hemodynamics. The five stages of cardiac damage were defined as follows: stage 0: no cardiac damage: absence of any of the following criteria, stage 1: left ventricular damage: left ventricular end-diastolic pressure >15 mmHg, stage 2: left atrial damage: mean pulmonary artery wedge pressure >15 mmHg, stage 3: pulmonary vascular damage: pulmonary vascular resistance >3 Wood units and/or invasively assessed systolic pulmonary artery pressure >60 mmHg, stage 4: right ventricular damage: mean right atrial pressure >15 mmHg. Patients were hierarchically classified in a given stage (worst stage) if the criterion was met for that stage. Cardiovascular Medicine · PDF of the online version · Published under the copyright license "Attribution -Non-Commercial -No Derivatives 4.0". No commercial reuse without permission. See
doi:10.4414/cvm.2019.02047 fatcat:nc3janeqzncfbhbm6uozsv6a6e