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The aim of this study was to evaluate the effect of age on proteoglycans size in equine articular cartilage. Cartilage samples were obtained from metacarpophalangeal joints of crossbred equines inmediatelly after slaughter, and alloted in three groups according to the equine's age: 1.5-2 years (n = 7); 4-5 years (n = 6) and over 10 years (n = 4). The cartilage extracts (100 mg /pair joints) were pooled for each age group and fractionated by exclution and ion exchange gel chromatography.doi:10.4067/s0301-732x2006000300007 fatcat:onnnwcqvojg5rlyfh7xmu7lmnm