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A 61-year-old man, consulted the clinic for dyspnea and cough worsening for 15 days. His past medical history was limited to a cutaneous melanoma 15 years previously, treated by surgery. He was thought to be cured, and was relapse free for the subsequent five years. Echocardiography revealed a large intracardiac mass occupying at least three quarters of the right ventricle, extending to the outflow tract. Echocardiography, MRI findings and anatomopathological examination are presented. Melanomadoi:10.2169/internalmedicine.47.0554 pmid:18310976 fatcat:4pukbnh7fvdsnguslifhct5muu