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THE PREPARATION AND EMPLOYMENT, IN A SERIES OF CASES, OF A POTENT POLYVALENT ANTISTAPHYLOCOCCIC SERUM

B. A. THOMAS
1913 Journal of the American Medical Association (JAMA)  
that of the Mexican hoy, became restless and ill. tempered, lie bit the grocery boy (on the hand) and a young hog (on Ihe nose) before he was frightened away by the owner. Three days Inter il, was noticed Hint something was wrong with the (log's left hind leg. When he wanted lo lie down he would tiltil round and round several limes from right lo left .-11111 then when he allowed his left thigh (.0 touch the floor lie would at, once bound up with a sharp cry, holding (lie leg in the air and
more » ... in the air and whining as if in pain, 'the following day the lc, was completely paralyzed, and there was a weakness of Ihe corresponding front, leg and neck. The development of the lia la lysis, preceded by a left, hemiplegia, and followed by death, was the same as seen in the rabbits. (The brain was sent lo the local I'aslcur institute anil they reported the pres¬ ence of \cgri bodies.) The grocery man was immediately stalled on Pasteur treatment, and the bitten hog isolated. (Ill November 12 the liog became restless and began to limp with the left hind leg: il was unable to drink. 1 hough it made fre¬ quent attempts and would put its head to the level id' its 1 yes in a bucket of water; salivation became marked, anil progressive paralysis and death, as seen in the rabbits, fol¬ lowed t he next, day. An interesting point hen-is the fact that a "mad" foxterrier at. almost precisely the same time bit a man and a luv;. The man was given I'aslcur treatment, anil is well, while Hie hog received no treatment and die 1 of rabies. SUMMARY 1. These eases are reported lo call attention (o the characteristic development of the paralysis of rabies as noted in a series of animals, including man. dog. hog, guinea-pigs and rabbits, 2. The initial site of paralysis was the "left hind leg," and this in a short lime developed into a left hcmiplegia, the paralysis eventually becoming general. :i. In an animal thai has suddenly become extremely nervous and irritable, the development of a weakness in the left hind leg, without any apparent reason, is suf¬ ficient to warrant a tentative diagnosis of rabies.
doi:10.1001/jama.1913.04340140032012 fatcat:skhxspdnkvfpfe7fttgfc6hpxa