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Full Thickness Wound Healing in Induced Diabetic Mice Using Low Level Laser in Comparison with Ultrasound

Thanaa I. Shalaby, Abd El Rahman T.Heraba, Maisa E.Moustafa, Amal S. El Sodfy
2017 International journal of Biomedical Engineering and Science  
Physical treatments such as therapeutic ultrasound and Laser are cited as important aides in wound management. This work expected to assess the role of ultrasound and laser on excisional wound healing progression in incited diabetic mice. Forty Swiss albino mice were divided into 2 groups; group I (diabetic free, 10mice) was used as a control group, while the other; group II(30 mice) was diabetic induced. Circular wounds were created on the dorsal fur of the animals. The wounds of laser treated
more » ... ds of laser treated group (N=10) were exposed to laser irradiation (830nm, 60mW), 5 minutes daily, 5 days/week until the wounds healed completely. The wounds of ultrasound treated group (N=10) were exposed to pulsed ultrasound (0.5 W/cm 2 , 1MHz) 5 minutes daily until the wounds healed completely. The untreated group (N=10) wound was left without treatment. The wounds for control group did not receive any type of treatment. The healing was noticed and assessed during the treatment period. Histological analysis of mice skin was accomplished at days 4, 10 and 15 post-wounding. Taking after healing period and determine the mechanical properties of healed skin. By looking at results acquired from various treatment modalities, we found that the two remedial devices encourage and quicken diabetic injury recuperating and enhancing scar quality yet with various degrees. Lighted injury with laser exhibited a more propelled recuperating process than ultrasound treated gathering. We can conclude that, both low-power laser and ultrasound treatments may quicken cutaneous injury mending in diabetic injury model. This finding may widen current treatment regimens
doi:10.5121/ijbes.2017.4101 fatcat:jwnbmp65frfm3ahqobrhmvjag4