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eALPS: Estimating Abundance Levels in Pooled Sequencing Using Available Genotyping Data

Itamar Eskin, Farhad Hormozdiari, Lucia Conde, Jacques Riby, Christine F. Skibola, Eleazar Eskin, Eran Halperin
2013 Journal of Computational Biology  
Here, we propose a method (eALPS) that uses the genotype data in conjunction with the pooled sequence data in order to accurately estimate the proportions of the samples in the pool, even in cases where  ...  not all individuals in the pool were genotyped (eALPS-LD).  ...  The genotype data was also generated as part of (NIH) grant number 1R01CA154643-01A1.  ... 
doi:10.1089/cmb.2013.0105 pmid:24144111 pmcid:PMC4013753 fatcat:as2om222uvbalntok3h6gtugny

eALPS: Estimating Abundance Levels in Pooled Sequencing Using Available Genotyping Data [chapter]

Itamar Eskin, Farhad Hormozdiari, Lucia Conde, Jacques Riby, Chris Skibola, Eleazar Eskin, Eran Halperin
2013 Lecture Notes in Computer Science  
Here, we propose a method (eALPS) that uses the genotype data in conjunction with the pooled sequence data in order to accurately estimate the proportions of the samples in the pool, even in cases where  ...  not all individuals in the pool were genotyped (eALPS-LD).  ...  The genotype data was also generated as part of (NIH) grant number 1R01CA154643-01A1.  ... 
doi:10.1007/978-3-642-37195-0_4 fatcat:l6qwugtvbrfklgipckhiu2i23e

Early Alpine human occupation backdates westward human migration in Late Glacial Europe [article]

Eugenio Bortolini, Luca Pagani, Gregorio Oxilia, Cosimo Posth, Federica Fontana, Federica Badino, Tina Saupe, Francesco Montinaro, Davide Margaritora, Matteo Romandini, Federico Lugli, Andrea Papini (+23 others)
2020 biorxiv/medrxiv   pre-print
In Southern Europe, Early Epigravettian material culture was replaced by Late Epigravettian art and technology about 18-17 ka ago at the beginning of southern Alpine deglaciation, although available genetic  ...  Here we generate new genomic data from a human mandible uncovered at the Late Epigravettian site of Riparo Tagliente (Veneto, Italy), that we directly dated to 16,980-16,510 cal BP (2σ).  ...  sequence RSRS and the parameter-rsrs were given to estimate the haplogroups using Haplogrep2.  ... 
doi:10.1101/2020.08.10.241430 fatcat:mvk76pazbvhjnio5afz3ihic7e