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ccSOL omics: a webserver for solubility prediction of endogenous and heterologous expression in Escherichia coli

F. Agostini, D. Cirillo, C. M. Livi, R. Delli Ponti, G. G. Tartaglia
2014 Bioinformatics  
Here we introduce ccSOL omics, a webserver for largescale calculations of protein solubility.  ...  Validation on three independent sets indicates that ccSOL omics discriminates soluble and insoluble proteins with an accuracy of 74% on 31 760 proteins sharing 530% sequence similarity.  ...  ACKNOWLEDGEMENTS We thank A. Zanzoni and G. Bussotti for stimulating discussions.  ... 
doi:10.1093/bioinformatics/btu420 pmid:24990610 pmcid:PMC4184263 fatcat:yxsvnphkdvadpgix5w5p3la5me