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Keeping Your Headcount When All About You Are Losing Theirs: Downsizing, Voluntary Turnover Rates, and The Moderating Role of HR Practices

Charlie O. Trevor, Anthony J. Nyberg
2008 Academy of Management Journal  
, 2001; Trevor & Wazeter, 2006) .  ...  , 2001; Trevor, Gerhart, & Boudreau, 1997) .  ... 
doi:10.5465/amj.2008.31767250 fatcat:acdmcrmllrelfcynjet3a37pbq

Career choices for ophthalmology made by newly qualified doctors in the United Kingdom, 1974–2005

Trevor W Lambert, Michael J Goldacre, Anthony J Bron
2008 BMC Ophthalmology  
The paper aims to report trends in career choices for ophthalmology among UK medical graduates. Methods: Postal questionnaire surveys were undertaken of qualifiers from all UK medical schools in nine qualification years since 1974. Data were analysed by univariate cross-tabulation. The significance of comparisons between groups of doctors were calculated by the use of chi-squared tests and adjusted residuals. Results: Ophthalmology was the first choice of long term career for 2.3% of men and
more » ... 2.3% of men and 1.5% of women one year after qualification; 2.0% of men and 1.4% of women three years after; and 1.8% of men and 1.2% of women at five years. Comparing early choices with eventual destinations, 64% who chose ophthalmology in year one, 84% in year three, and 92% in year five eventually practised in the specialty. The concordance between year one choice and eventual destination was higher for ophthalmology than for most other specialties. 'Enthusiasm for and commitment to the specialty' was the most important single factor in influencing career choice. The prospect of good working hours and conditions was also an important influence: it influenced career choice a great deal for a higher percentage of those who chose ophthalmology (66% in the third year) than those who made other surgical choices (23%). Conclusion: Those choosing ophthalmology show a high level of commitment to it. Their commitment is strengthened by the prospect of attractive hours and working conditions. Many doctors who become ophthalmologists have already made their choice by the end of their first post-qualification year.
doi:10.1186/1471-2415-8-3 pmid:18318905 pmcid:PMC2311274 fatcat:bimvyhvq3rasboihm6wpnfupqa

A submersible battery-powered flow injection (FI) sensor for the determination of nitrate in estuarine and coastal waters

Anthony R. J. David, Trevor McCormack, Paul J. Worsfold
1999 Journal of automated methods & management in chemistry (Print)  
Reagent module PVC spacer rings Stainless steel tie rods LiRing bracket Tubing l Retaining screws ,/ , Pressure housing L111 -j !]  ... 
doi:10.1155/s1463924699000012 pmid:18924837 pmcid:PMC2548166 fatcat:ohk7gkgfwvbwpdhzirqzyjfp3m

The neuropsychological basis of addictive behaviour

Barry J Everitt, Anthony Dickinson, Trevor W Robbins
2001 Brain Research Reviews  
The argument advanced in this review is that drug addiction can be understood in terms of normal learning and memory systems of the brain which, through the actions of chronically self-administered drugs, are pathologically subverted, thereby leading to the establishment of compulsive drug-seeking habits, strengthened by the motivational impact of drug-associated stimuli and occurring at the expense of other sources of reinforcement. We review data from our studies that have utilized procedures
more » ... utilized procedures which reveal the various influences of pavlovian stimuli on goal-directed behaviour, namely discriminated approach, pavlovian-to-instrumental transfer and conditioned reinforcement, in order to demonstrate their overlapping and also unique neural bases. These fundamental studies are also reviewed in the context of the neural and psychological mechanisms underlying drug-seeking behaviour that is under the control of drug-associated environmental stimuli. The ways in which such drug-seeking behaviour becomes compulsive and habitual, as well as the propensity for relapse to drug-seeking even after long periods of relapse, are discussed in terms of the aberrant learning set in train by the effects of self-administered drugs on plastic processes in limbic cortical-ventral striatal systems.
doi:10.1016/s0165-0173(01)00088-1 pmid:11690609 fatcat:5xzd25ckh5bzfdp6v6edghowyi

Active video games for rehabilitation in respiratory conditions: a systematic review and meta-analysis (Preprint)

Joshua Simmich, Anthony J. Deacon, Trevor G. Russell
2018 JMIR Serious Games  
Exercise and physical activity are key components of treatment for chronic respiratory diseases. However, the level of physical activity and adherence to exercise programs are low in people with these diseases. Active video games (AVGs) may provide a more engaging alternative to traditional forms of exercise. This review examines the effectiveness of game-based interventions on physiological outcome measures, as well as adherence and enjoyment in subjects with chronic respiratory diseases. A
more » ... tory diseases. A systematic search of the literature was conducted, with full texts and abstracts included where they involved an AVG intervention for participants diagnosed with respiratory conditions. A narrative synthesis of included studies was performed. Additionally, meta-analysis comparing AVGs with traditional exercise was undertaken for 4 outcome measures: mean heart rate (HR) during exercise, peripheral blood oxygen saturation (SpO2) during exercise, dyspnea induced by the exercise, and enjoyment of the exercise. A total of 13 full-text papers corresponding to 12 studies were included in the review. Interventions predominantly used games released for the Nintendo Wii (8 studies) and Microsoft Xbox Kinect (3 studies). There were 5 studies that examined the acute effects of a single session of AVGs and 7 studies that examined the long-term effects after multiple sessions of AVGs. Trials conducted over more than 1 session varied in duration between 3 and 12 weeks. In these, AVG interventions were associated with either similar or slightly greater improvements in outcomes such as exercise capacity when compared with a traditional exercise control, and they also generally demonstrated improvements over baseline or nonintervention comparators. There were a few studies of unsupervised AVG interventions, but the reported adherence was high and maintained throughout the intervention period. Additionally, AVGs were generally reported to be well liked and considered feasible by participants. For outcome measures measured during a single exercise session, there was no significant difference between an AVG and traditional exercise for HR (mean difference 1.44 beats per minute, 95% CI -14.31 to 17.18), SpO2 (mean difference 1.12 percentage points, 95% CI -1.91 to 4.16), and dyspnea (mean difference 0.43 Borg units, 95% CI -0.79 to 1.66), but AVGs were significantly more enjoyable than traditional exercise (Hedges g standardized mean difference 1.36, 95% CI 0.04-2.68). This review provides evidence that AVG interventions, undertaken for several weeks, can provide similar or greater improvements in exercise capacity and other outcomes as traditional exercise. Within a single session of cardiovascular exercise, an AVG can evoke similar physiological responses as traditional exercise modalities but is more enjoyable to subjects with chronic respiratory diseases. However, there is very limited evidence for adherence and effectiveness in long-term unsupervised trials, which should be the focus of future research.
doi:10.2196/10116 pmid:30801256 pmcid:PMC6409512 fatcat:f2csjf6a6nfg5o2qvmqeovvt3a

Pay-for-Performance's Effect on Future Employee Performance

Anthony J. Nyberg, Jenna R. Pieper, Charlie O. Trevor
2016 Journal of Management  
multiple pay hierarchies (Trevor & Wazeter, 2006) .  ...  .01 .01 .01 .02 .02 .02 Salary P a yf o r -P e r f o r m a N c e ' s e f f e c T o N f u T u r e e m P l o y e e P e r f o r m a N c e N y b e r g , P i e P e r , & T r e v o r i N J  ... 
doi:10.1177/0149206313515520 fatcat:uzdc57x2jnfojevwd6fyq6ezde

Studies Towards the Synthesis of Salvinorin A

Anthony R. Lingham, Helmut M. Hügel, Trevor J. Rook
2006 Australian journal of chemistry (Print)  
= 9.6 Hz, H-1), 3.49 (1H, s, OH), 3.26 (1H, dq, J1 = 6.6 Hz, J2 = 9.6 Hz, H-2), 2.62 (3H, s, NCH 3 ), 2.25 (3H, s, H-6''), 0.81 (3H, d, J = 6.6 Hz, H-3). 13 C (75MHz; CDCl 3 ) 152.5 (C-5''), 141.5 (C  ...  solution through a short silica column, deactivated with triethylamine. 1 H (300MHz; CDCl 3 ) 7.45-7.25 (5H, m, H-2', H-3', H-4', H-5', H-6'), 6.88 (1H, s, H-2''), 5.95 (1H, s, H-4''), 4.47 (1H, d, J  ... 
doi:10.1071/ch05338 fatcat:snfqadqhsrgc7n7kt7uunjhr2q

Diels–Alder Reactions of 3-Furylamines in Organic and Aqueous Solvents

Anthony R. Lingham, Helmut M. Hügel, Trevor J. Rook
2006 Australian journal of chemistry (Print)  
Various 5-methyl-3-aminofurans have been shown to undergo facile Diels-Alder reactions with methyl acrylate in aqueous media. Reactions proceeded with exclusive regiochemistry, and enamine cycloadducts were readily hydrolysed to afford 7oxabicyclo[2.2.1]heptanones in high yields.
doi:10.1071/ch05339 fatcat:tfoprmka7vaprmvepkh4qiyj3u

Muscle damage produced by isometric contractions in human elbow flexors

Trevor J. Allen, Tyson Jones, Anthony Tsay, David L. Morgan, Uwe Proske
2018 Journal of applied physiology  
1.75 s 63.6 (7.4) 46.7 (4.3) 52.1* (6.1) 60.4* (7.5) 5 Control 3 s 61.9 (10.9) 46.1 (9.1) 48.0 (7.7) 52.3 (9.2) Experimental 3 ϫ 1 s 62.1 (11.6) 43.9 (8.8) 47.7 (8.6) 51.3 (9.1) J  ... 
doi:10.1152/japplphysiol.00535.2017 pmid:29074710 fatcat:5b2npj56sngsjmuzpis6aeeinu

Spatial Point Pattern Analysis and Its Application in Geographical Epidemiology

Anthony C. Gatrell, Trevor C. Bailey, Peter J. Diggle, Barry S. Rowlingson
1996 Transactions of the Institute of British Geographers  
Anthony Gatrell is grateful to Lancaster University for granting the study leave that permitted completion of this paper and he and Trevor Bailey would like to thank the Department of Mathematical Statistics  ...  Finally, as an educational aid, Trevor Bailey has written a package for interactive spatial data analysis called INFO-MAP (Bailey 1990; Bailey and Gatrell 1995) .  ...  We say that a point process is stationary if the intensity is constant over R, so that (s)= and, in addition, (s i , s j )= (s i −s j )= (d).  ... 
doi:10.2307/622936 fatcat:xk6mfrclzjcefldbm77kr3y4j4

Cretaceous fore-arc basalts from the Tonga arc: Geochemistry and implications for the tectonic history of the SW Pacific

Trevor J. Falloon, Sebastien Meffre, Anthony J. Crawford, Kaj Hoernle, Folkmar Hauff, Sherman H. Bloomer, Dawn J. Wright
2014 Tectonophysics  
Tulloch, A.J., Ramezani, J., Mortimer, N., Mortensen, J., Van Den Bogaard., P., and Maas, R., 2009.  ...  basin: evidencefrom site 840 on the Tonga Ridge, in J. Hawkins, L.Parson, J. Allan et al. (eds), Proc. ODP, Sci. Results, 135, OceanDrilling Program, College Station, Texas, 367-372.  ... 
doi:10.1016/j.tecto.2014.05.007 fatcat:pmo6bvvw7zc2pi5buqenbgexhi

Calcic melt inclusions in primitive olivine at 43°N MAR: evidence for melt–rock reaction/melting involving clinopyroxene-rich lithologies during MORB generation

Vadim S Kamenetsky, Stephen M Eggins, Anthony J Crawford, David H Green, Massimo Gasparon, Trevor J Falloon
1998 Earth and Planetary Science Letters  
Olivine-hosted homogenized melt inclusions in a primitive basalt AII32-12-7 from 43ºN Mid-Atlantic Ridge have magnesian basalt compositions (10-12 wt% MgO) with high CaO (13.2-15.2 wt%), relatively low Al 2 O 3 (12.8-15.5 wt%), and form a linear array that ranges to extremely high CaO=Al 2 O 3 values (0.8-1.2). These melt compositions are unusual for MORB, as is the observed phenocryst assemblage, which comprises primitive olivine (Fo 87-92 with up to 0.45 wt% CaO), Cr-diopside (Mg# 90-92), and
more » ... de (Mg# 90-92), and Cr-rich spinel (Cr# 50-70) and directly reflects these melt compositions. The melt compositional array extends from peridotite-saturated compositions formed near 1 GPa to lie well within the clinopyroxene phase volume, or possibly along a clinopyroxene C olivine phase boundary. We interpret the array as either the product of melt-wallrock reaction between a 1 GPa MORB melt and a clinopyroxene-rich lithology (wehrlite or clinopyroxenite), or of mixing between melt fractions derived separately from these distinct lithologies (i.e. peridotite and clinopyroxenite=wehrlite). Derivation of the melt array from a conventional mantle peridotite source, possibly involving fractional melting near or beyond the point of clinopyroxene exhaustion, is inconsistent with the melt compositions and the trend of the array. Trace element abundance patterns in the melt inclusions range from depleted to highly enriched (e.g. La n =Yb n 0.6-7.0), and indicate the generation of compositionally diverse melt fractions via fractional melting processes and=or melting of geochemically distinct source heterogeneities. Most melt inclusions, and the pillow-rim glass, are enriched in the more incompatible trace elements, and have high Nb and Ta contents relative to other highly incompatible elements. These characteristics and the Pb isotopic composition of the pillow-rim glass ( 206 Pb= 204 Pb D 19.654) indicate the presence of a HIMU mantle source component that can be linked to lateral dispersion of a geochemical signal commonly attributed to the Azores mantle plume.
doi:10.1016/s0012-821x(98)00090-9 fatcat:tqst7b4cgzcbvewhx4i42fzlni

Role of 1-methyl-4-phenylpyridinium ion formation and accumulation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity to isolated hepatocytes

Donato Di Monte, Gunilia Ekström, Toshihiro Shinka, Martyn T. Smith, Anthony J. Trevor, Neal Castagnoli
1987 Chemico-Biological Interactions  
The parkinsonian-inducing compound 1-methyl-4-phenyl-l,2,3,6-tetrahydropyridine (MPTP) is converted by isolated hepatocytes to its primary metabolite, the 1-methyl-4-phenyl-2,3-dihydropyridinium ion (MPDP +), and to its fully oxidized derivative, 1-methyl-4-phenylpyridinium ion (MPP+). Only the latter, however, accumulates in the cells. Incubation of hepatocytes in the presence of MPDP + also results in the selective intracellular accumulation of MPP +. Conversion to MPP + is more rapid and
more » ... more rapid and extensive after exposure to MPDP +, than with MPTP and the former is also more toxic. Addition of MPP + itself is toxic to hepatocytes but only after a long lag period, which presumably reflects its limited access to the cell and its relatively slow intracellular accumulation. As previously shown with MPTP and MPP +, the cytotoxicity of MPDP ÷ is dose-dependent and is consistently preceeded by complete depletion of intracellular ATP. Similar to MPP ÷ but not MPTP, MPDP ÷ causes a comparable rate and extent of cytotoxicity and ATP loss in hepatocytes pretreated with the monoamine oxidase inhibitor pargyline. Pargyline blocks hepatocyte biotransformation of MPTP to MPP +, but it has no significant effect on MPP ÷ accumulation after exposure to either MPDP + or MPP +. It is concluded that MPTP is toxic to hepatocytes via its monoamine oxidase-dependent metabolism and that MPP ÷ is likely to be the ultimate toxic metabolite which accumulates in the cell, causing ATP depletion and eventual cell death.
doi:10.1016/0009-2797(87)90083-4 pmid:3496169 fatcat:beaxa3ijpjh4zillgjgu3xry6q

Three-dimensional cartilage tissue engineering using adult stem cells from osteoarthritis patients

Wael Kafienah, Sanjay Mistry, Sally C. Dickinson, Trevor J. Sims, Ian Learmonth, Anthony P. Hollander
2006 Arthritis & Rheumatism  
Objective. To determine whether it is possible to engineer 3-dimensional hyaline cartilage using mesenchymal stem cells derived from the bone marrow (BMSCs) of patients with osteoarthritis (OA). Methods. Expanded BMSCs derived from patients with hip OA were seeded onto polyglycolic acid scaffolds and differentiated using transforming growth factor ␤3 in the presence or absence of parathyroid hormone-related protein (PTHrP) to regulate hypertrophy. Micromass pellet cultures were established
more » ... re established using the same cells for comparison. At the end of culture, the constructs or pellets were processed for messenger RNA (mRNA) analysis by quantitative real-time reverse transcription-polymerase chain reaction. Matrix proteins were analyzed using specific assays. Results. Cartilage constructs engineered from BMSCs were at least 5 times the weight of equivalent pellet cultures. Histologic, mRNA, and biochemical analyses of the constructs showed extensive synthesis of proteoglycan and type II collagen but only low levels of type I collagen. The protein content was almost identical to that of cartilage engineered from bovine nasal chondrocytes. Analysis of type X collagen mRNA revealed a high level of mRNA in chondrogenic constructs compared with that in undifferentiated BMSCs, indicating an increased risk of hypertrophy in the tissue-engineered cells. However, the inclusion of PTHrP at a dose of 1 M or 10 M during the culture period resulted in significant suppression of type X collagen mRNA expression and a significant decrease in alkaline phosphatase activity, without any loss of the cartilagespecific matrix proteins. Conclusion. Three-dimensional hyaline cartilage can be engineered using BMSCs from patients with OA. This method could thus be used for the repair of cartilage lesions.
doi:10.1002/art.22285 pmid:17195220 fatcat:dxp2fjyx5bfiplqq26gm3oywhi

The baryon budget on the galaxy group/cluster boundary

Alastair J. R. Sanderson, Ewan O'Sullivan, Trevor J. Ponman, Anthony H. Gonzalez, Suresh Sivanandam, Ann I. Zabludoff, Dennis Zaritsky
2013 Monthly notices of the Royal Astronomical Society  
We present a study of the hot gas and stellar content of 5 optically-selected poor galaxy clusters, including a full accounting of the contribution from intracluster light (ICL) and a combined hot gas and hydrostatic X-ray mass analysis with XMM observations. We find weighted mean stellar (including ICL), gas and total baryon mass fractions within r500 of 0.026+/-0.003, 0.070+/-0.005 and 0.096+/-0.006, respectively, at a corresponding weighted mean M500 of (1.08_{-0.18}^{+0.21}) x 10^14 Msun.
more » ... 1}) x 10^14 Msun. Even when accounting for the intracluster stars, 4 out of 5 clusters show evidence for a substantial baryon deficit within r500, with baryon fractions (f_bary) between 50+/-6 to 59+/-8 per cent of the Universal mean level (i.e. Omega_b / Omega_m); the remaining cluster having f_bary = 75+/-11 per cent. For the 3 clusters where we can trace the hot halo to r500 we find no evidence for a steepening of the gas density profile in the outskirts with respect to a power law, as seen in more massive clusters. We find that in all cases, the X-ray mass measurements are larger than those originally published on the basis of the galaxy velocity dispersion (sigma) and an assumed sigma-M500 relation, by a factor of 1.7-5.7. Despite these increased masses, the stellar fractions (in the range 0.016-0.034, within r500) remain consistent with the trend with mass published by Gonzalez, Zaritsky & Zabludoff (2007), from which our sample is drawn.
doi:10.1093/mnras/sts586 fatcat:ava2xzxeufditjha52lrp5j3fq
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