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The removal of distally fixed, uncemented, femoral components is one of the major challenges in revision orthopaedic surgery. Saw blades often have insufficient length to reach the distal part of the component and long chisels are inevitably wider proximally and can cause metaphyseal damage. We report the use of Illizarov wires passed serially using a power driver between the implant and host bone to divide the distal bone implant interface ( Fig. 1) . Their flexibility minimises damage to thedoi:10.1308/rcsann.2006.88.6.592b pmcid:PMC1963755 fatcat:iksy5htceje3nk4u5rvrnbg52i
more »... ises damage to the proximal femur and the femoral component can be removed without resorting to femoral osteotomy and the attendant increased morbidity and complications. Antegrade stripping of the above-knee segment of the long saphenous vein (LSV) is a standard part of varicose vein surgery for saphenofemoral incompetence. Our unit uses a pin stripper to achieve satisfactory disruption of the above knee portion of the LSV. We describe a technique to improve pain control following a LSV strip. The LSV is stripped in the standard manner using a pinstripper that is tied to the proximal LSV using a 0 Vicryl™ (Ethicon, Edinburgh EH11 4HE, UK) tie. It is essential that the trailing length of tie be of sufficient distance to allow retrograde insertion of a size 7 umbilical catheter. Following removal of the pin stripper and LSV through a distal incision, the Vicryl tie is used to attach a size 7 umbilical catheter. Traction on the Vicryl tie from above allows the catheter to be drawn into the leg where the LSV has been stripped. Following this, 15 ml of 0.25% Chirocaine (Celltech, Cambridge CB4 4WE, UK) can be instilled as the catheter is removed, thus ensuring the bed of the LSV is adequately anaesthetised. We find this technique to be both simple and effective. A bleeding arteriovenous fistula can be a nightmare in peripheral haemodialysis units and such patients need to be transferred quickly to a surgical unit for intervention. We describe a simple
David P. MAGEE David P. Magee received his B.S. degree in Mechanical Engineering from Oklahoma State University, Stiliwater, OK, in 1989. ... Wayne J. BooK Wayne J. Book is Professor of Mechanical Engineering at the Georgia Institute of Technology where he teaches courses in system dynamics, controls, robotics and manufacturing systems. ...doi:10.11499/sicejl1962.32.4_309 fatcat:rjxfrc4x3fbqxaialjjdeq2exe
Creation of a retrogastric tunnel in laparo- scopic gastric banding -the Liverpool Landmark JONATHAN BARRY, CONOR J MAGEE, DAVID KERRIGAN Gravitas, Bourne End, UK CORRESPONDENCE TO David Kerrigan, Gravitas ...doi:10.1308/rcsann.2010.92.3.266 pmid:20425898 pmcid:PMC3080056 fatcat:jg5u37a6krbmxf6rx2zpnh6zrm
2014) Interrogation of modern and ancient genomes reveals the complex domestic history of cattle. Animal Frontiers, 4 (3). pp. 7-22.doi:10.2527/af.2014-0017 fatcat:22xkyeik5jhjrcq6dw4nn6jih4
The robustness for the normalized time-delay value of T* =•¬can also be seen in the frequency do- J. Book David P. ...  David P. ...doi:10.7210/jrsj.17.761 fatcat:hc5b44dvxrf4rc5exo2a4tpjuy
Objective: To examine the effects of muscle trauma and cold application on indicators of oxygen free radical (OFR) and protein levels in exercise trained rat skeletal muscle. Design: Randomized intervention study following an exercise training program. Skeletal muscle tissue analysis 72 hours after trauma and cold treatments. Setting: University animal research laboratory. Subjects: 70 female Sprague-Dawley rats weighing 200-250 grams, housed in wire cages, provided with rat food and water addoi:10.1589/jpts.13.21 fatcat:nj2uy754xvcofcpeodasyka77m
more »... food and water ad libitum. Interventions: 35 rats took part in a daily running program for 8 weeks. After the training program, 28 rats were randomly assigned to one of four groups to study indices of OFR levels after trauma and cold treatments. Further, 28 rats were randomly assigned to one of four groups to study muscle protein content after trauma and cold treatment. A sedentary group (N=7) was included in each analysis as a control group. Groups that received trauma were subjected to a single impact blunt trauma to the medial aspect of the gastrocnemius muscle of the left leg. Following the trauma procedure, groups that received cold treatment had 6 cold applications for 10 minutes, twice per day over a 72 hour period with a 3 × 2 inch gel cold pack, stored at -4°C. Main outcome measures: Medial gastrocnemius muscles were analyzed at 72 hours post-trauma for citrate synthase, indicators of OFR (malonaldehyde and lipofuscin) and protein content. Results: After the endurance training program, significant increases (p<0.05) in citrate synthase activity and protein levels were elicited, but the indices of lipid peroxidation (OFR indicators) were unaltered when compared to sedentary and exercise groups. Following trauma, the net loss of pre-existing protein was statistically significant (p<0.05) and lipid peroxidation activity increased slightly, but not significantly. Further, modulations in lipid peroxidation and protein content were induced in muscle by cold treatment followed by trauma (p<0.05) as the application of cold prevented or delayed indicators of OFR activity and protein loss in the medial gastrocnemius muscle. Conclusions: Cold treatment applied to traumatized muscle significantly decreased lipofuscin content (indices of OFR) and offset the catabolic response in protein content during the inflammatory phase. The early application of cold immediately after trauma is recommended within the protocol guidelines.
doi:10.1007/s10557-017-6755-9 pmid:28956186 pmcid:PMC5730625 fatcat:yjlgjqujbfd6fmqw5csf25qzya
Madin-Darby canine kidney (MDCK) cells are unable to form desmosomes when cultured in low-calcium medium ([Caz+]<O.l meq./l), but can be induced to do so by raising the calcium to physiological concentrations (l-2 meq./l). We have previously demonstrated that this block correlated with increased desmosomal protein turnover. Here we have immunoprecipitated the major desmosome glycoproteins [DGI (150 kDa) and DGII/III (120/100 kDa)] from non-ionic detergent-soluble and -insoluble fractionsdoi:10.1016/0014-5793(89)81229-3 pmid:2651159 fatcat:t3qsq5vc55ds7jfrgfpujbwrta
more »... le fractions prepared from metabolically labelled MDCK cells cultured in standard or lowcalcium medium. Pulse-chase studies showed that both DGI and DGII/III became unextractable in non-ionic detergent before their arrival at the cell surface, whether cells were grown in standard or low-calcium medium. The non-ionic detergent insolubility of these membrane components is therefore a separate step which precedes the formation of morphologically recognisable desmosomes.
J Clin Epidemiol. 2000;53: 964 -972. 134 Moher D, Pham B, Lawson ML, Klassen TP. The inclusion of reports of randomised trials published in languages other than English in systematic reviews. ...doi:10.2522/ptj.20090335 pmid:20651012 fatcat:7r3f5rcodzgtfnh2dr3tbsvisu
doi:10.1067/mge.2002.122584 pmid:11923786 fatcat:imuapt26wvfwlpha7zs7v5x4ku
Acknowledgments We thank J. Price, C. Hughes, L. Flaherty, K. Burgess, K. ... ϭ 7 Hz); 2.10 (H9, J ϭ 7 Hz); 2.01 (H8, J ϭ 7 Hz); 1.84 (H13, J ϭ 2, 1 Hz); 1.70 (H12, J ϭ 2, 1 Hz); 1.66 (H14, J ϭ 2, 1 Hz); 1.62 (H15); GC/EAD Analyses. ... Spectral data for (3Z, 6E)-␣-farnesene ( Fig. 1C) were: 1 H (400 MHz, CDCl 3 ): 6.83 (H2, J ϭ 17, 11, 1 Hz); 5.38 (H4, J ϭ 7 Hz); 5.23 (H1b, J ϭ 17 Hz); 5.13 (H6); 5.12 (H1a); 5.10 (H10); 2.89 (H5, J ...doi:10.1603/en10156 pmid:22182567 fatcat:yihybcwohjbwdmaydxq5fvhchy
39 -1.64 1.09 92 -1.82 2.09 0.52 Weight z-score 39 -1.63 0.94 92 -1.60 2.67 0.93 Weight-adjusted-for-height z-score 26 -0.86 1.40 50 -0.71 2.26 0.72 J ... Characteristics of Alagille syndrome patients in whom fecal elastase data were collected as compared to the remainder of the Alagille study cohort Fecal Elastase Collected N=42 Fecal Elastase Missing N=102 N J ...doi:10.1097/mpg.0b013e31825eff61 pmid:22614108 pmcid:PMC3666161 fatcat:gceuufzzfjduhk34nlgsmdgi3y
Research Trauma-related admissions to intensive care units in Australia: the influence of Indigenous status on outcomes Fraser Magee 1 , Anthony Wilson 2 , Michael J Bailey 3 , David Pilcher 1,4 , Paul ... J Secombe 3,5 , Paul Young 6 , Rinaldo Bellomo 7 T rauma is the second most frequent cause of death among Aboriginal and Torres Strait Islander (Indigenous) Australians. 1 Indigenous Australians have ...doi:10.5694/mja2.12028 pmid:30644562 fatcat:b2nqvlzjbreh5pdasfuijjteem
Food & Function
Increasing global aquaculture production, is putting pressure on fishmeal and fish oil supply. There is therefore a growing search for more sustainable sources of proteins and polyunsaturated fatty acids as fish feed ingredients.doi:10.1039/c8fo02109k fatcat:essu32mbkvhwtlil664g6b3j3u
Purpose: Shoulder pain and dysfunction may occur after surgery for head and neck cancer (HNC) as a result of damage to or resection of the spinal accessory nerve. Previous research found that 12 weeks of upper extremity progressive resistance exercise training (PRET) improved shoulder outcomes in survivors of HNC; the purpose of this study was to determine whether benefits persisted over the longer term. Methods: Survivors of HNC were assigned at random to PRET (n ¼ 27) or a standarddoi:10.3138/ptc.2014-13o pmid:25931658 pmcid:PMC4403331 fatcat:2txcpf5adjazpikdb5wovtmfee
more »... standard therapeutic protocol (TP; n ¼ 25), with an opportunity for crossover in the TP group after 12 weeks. At 12month follow-up, participants were mailed a questionnaire that assessed quality of life (QOL), shoulder outcomes, and exercise behaviour. Results: Of the 52 participants enrolled in the study, 44 were eligible at 12-month follow-up, and 37 (71%) completed the questionnaires. Overall, self-reported outcomes were largely sustained over the follow-up period. After 12 months, regardless of original group allocation, participants who continued resistance exercise training during the follow-up period reported better neck dissection-related functioning (p ¼ 0.021) and better QOL (p ¼ 0.011) than those who did not. Conclusions: Benefits of PRET were sustained at 12-month follow-up. Ongoing participation in resistance exercise training may prove valuable as a supportive care intervention for survivors of HNC.
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