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A Unique, Innovative, and Clinically Oriented Approach to Anatomy Education

Richard L. Drake
2007 Academic Medicine  
The establishment of The Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, whose first class entered in 2004, provided a unique opportunity to design an anatomy program that, from all indications, is effective, time efficient, and clinically relevant in the context of a nonlecture, problem-based, organ-systems-oriented curriculum. Through consultation with surgery colleagues, the case-directed anatomy program was developed. This approach, meeting one day a week for
more » ... one day a week for 1 hour 50 minutes for 30 weeks, uses clinical cases to introduce anatomical information that is reinforced using prosected cadavers and imaging. The
doi:10.1097/acm.0b013e31803eab41 pmid:17457071 fatcat:d4ixggo5u5apzp3jdd3h7myz6y

Alien Earth: Glint observations of a remote planet

Richard K. Barry, L. Drake Deming
2010 Proceedings of the International Astronomical Union  
We give a preliminary report on a multi-wavelength study of specular reflections from the oceans and clouds of Earth. We use space-borne observations from a distance sufficient to ensure that light rays reflected from all parts of Earth are closely parallel, as they will be when studying exoplanets. We find that the glint properties of Earth in this far-field vantage point are surprising -in the sense that some of the brightest reflections are not from conventional ocean-glints, but appear to
more » ... ts, but appear to arise from cirrus cloud crystals. The Earth observations discussed here were acquired with the High Resolution Instrument (HRI) -a 0.3 m f/35 telescope on the Deep Impact (DI) spacecraft during the Extrasolar Planet Observation and Characterization (EPOCh) investigation.
doi:10.1017/s1743921311020849 fatcat:sj3chmgnvbcadmmqanjujgi5ka

Rewarding the resident teacher

Jennifer M. McBride, Richard L. Drake
2011 Anatomical Sciences Education  
The anatomy program follows these guidelines by using clinical cases to introduce anatomical concepts and facts that are reinforced using cadavers and imaging (Drake, 2007) .  ...  The prosection approach saves a significant amount of time (Nnodim, 1990 (Nnodim, , 1996 Drake et al., 2009 ) and evidence suggests that students learn anatomy using prosections as well as students doing  ... 
doi:10.1002/ase.213 pmid:21480537 fatcat:okmggqkukbhrdacjhmqffmhofe

Laboratory study of submerged metal-mine tailings 1: Effect of solid-liquid contact time and aeration on contaminant concentrations

Richard D. Doepker, Pamela L. Drake
1991 Mine Water and the Environment  
( G r 4 3 8 l l z a m 3 42 NA No analys~s.  ...  fkom the 4-L bottles.  ... 
doi:10.1007/bf02914807 fatcat:623yzrbivnfppcpltsdr7kz3eu

Cost–effectiveness analysis of pandemic influenza preparedness: what's missing?

Tom L Drake, Zaid Chalabi, Richard Coker
2012 Bulletin of the World Health Organization  
Correspondence to Tom L Drake (e-mail:  ...  Using the perspec- Cost-effectiveness analysis of pandemic preparedness Tom L Drake et al. Cost-effectiveness analysis of pandemic influenza preparedness: what's missing?  ... 
doi:10.2471/blt.12.109025 pmid:23284200 pmcid:PMC3524962 fatcat:os7sby35crg4vczt5t5mktxmhu

Massive Splenomegaly Due to Diffuse Splenic Hemangioma with Extramedullary Hematopoiesis

Stephen L. Strobel, Richard D. Drake, Rick Graham
2002 Journal of Histotechnology  
Although most of these lesions co-exist with normal splenic
doi:10.1179/his.2002.25.1.11 fatcat:o5w3usvctvca3cljgz5vjeaa2i

Massive Splenomegaly Due to Diffuse Splenic Hemangioma with Extramedullary Hematopoiesis

Stephen L. Strobel, Richard D. Drake, Rick Graham
2002 Journal of Histotechnology  
Although most of these lesions co-exist with normal splenic
doi:10.1179/014788802794792671 fatcat:3cgspexdijgw7g4jeyimprq7t4

To what extent is cadaver dissection necessary to learn medical gross anatomy? A debate forum

Geoffrey D. Guttmann, Richard L. Drake, Robert B. Trelease
2004 The Anatomical Record  
doi:10.1002/ar.b.20042 pmid:15558790 fatcat:rn6ggg5aynb4dehsqhou3ltjuu

Acetogenic and Sulfate-Reducing Bacteria Inhabiting the Rhizoplane and Deep Cortex Cells of the Sea Grass Halodule wrightii †

Kirsten Küsel, Holly C. Pinkart, Harold L. Drake, Richard Devereux
1999 Applied and Environmental Microbiology  
; L-lysine-HCl, 0.5; cellulose, 7.0; Na 2 S ⅐ 9H 2 O (as the reducing agent), 0.5; and the redox indicator resazurin, 0.001.  ...  Cells hybridizing with the AW probe were found in dense clusters (arrow) on the outer root surface. 2 ⅐ 6H 2 O, 0.2; FeCl 3 ⅐ 6H 2 O, 0.2; methylene blue, 0.002; yeast extract, 1.0; L-arginine-HCl, 0.5  ... 
doi:10.1128/aem.65.11.5117-5123.1999 fatcat:4hnah7wfdndxlmwfpsa7uzxuci

Correction: Correlative Gene Expression to Protective Seroconversion In Rift Valley Vaccinates

Richard C. Laughin, Kenneth L. Drake, John C. Morrill, L. Garry Adams
2016 PLoS ONE  
doi:10.1371/journal.pone.0156469 pmid:27214231 pmcid:PMC4877044 fatcat:gdzljiv6dfdcxbv3q35rl5xeuy

Identification and Molecular Cloning of a Unique Hyaluronan Synthase fromPasteurella multocida

Paul L. DeAngelis, Wei Jing, Richard R. Drake, Ann Mary Achyuthan
1998 Journal of Biological Chemistry  
These findings suggested that the Tn elements in mutants H and L were indeed responsible for disrupting the HA biosynthesis locus.  ...  The Tn916 elements in the P. multocida acapsular mutants H and L were not integrated directly in the HAS gene but rather were located in the KfaA homolog gene.  ... 
doi:10.1074/jbc.273.14.8454 pmid:9525958 fatcat:mxorcueok5d4natgkeaxpdgcdq

A Systematic Review of Carotenoids in the Management of Age-Related Macular Degeneration

Drake W. Lem, Pinakin Gunvant Davey, Dennis L. Gierhart, Richard B. Rosen
2021 Antioxidants  
Dennis L. Gierhart is the Chief Scientific officer of, and is employed by, ZeaVision LLC. Richard B. Rosen has received research support from ZeaVision and Guardion Health.  ...  Drake Lem, none. Pinakin Davey serves as a consultant to ZeaVision LLC, which manufactures various nutritional supplements-none of which were used in this study.  ... 
doi:10.3390/antiox10081255 fatcat:v3ubpkjwgfdz5ebbi6g5kjsbyq

Liquid-phase oxidation of alkylaromatics by a H-atom transfer mechanism with a new heterogeneous CoSBA-15 catalyst

Richard L. Brutchey, Ian J. Drake, Alexis T. Bell, T. Don Tilley
2005 Chemical Communications  
L n M[OSi(O t Bu) 3 ] m , as heterogeneous oxidation catalysts, the new pseudo-tetrahedral Co(II) complex, (4,49-di-t Bu-bipy)Co[OSi(O t Bu) 3 ] 2 (1) was prepared, and its immobilization onto SBA-15  ...  Additionally, three weak absorbances were observed at l max 5 496, 584 and 657 nm which are characteristic of d-d transitions for pseudo-tetrahedral Co(II) species, 8, 9 as also observed in the solution  ... 
doi:10.1039/b506426k pmid:16027928 fatcat:jhvffy3ydff3bfdmxkn2qy4ujq

Correlative Gene Expression to Protective Seroconversion in Rift Valley Fever Vaccinates

Richard C. Laughlin, Kenneth L. Drake, John C. Morrill, L. Garry Adams, Kylene Kehn-Hall
2016 PLoS ONE  
Rift Valley fever Virus (RVFV), a negative-stranded RNA virus, is the etiological agent of the vector-borne zoonotic disease, Rift Valley fever (RVF). In both humans and livestock, protective immunity can be achieved through vaccination. Earlier and more recent vaccine trials in cattle and sheep demonstrated a strong neutralizing antibody and total IgG response induced by the RVF vaccine, authentic recombinant MP-12 (arMP-12). From previous work, protective immunity in sheep and cattle
more » ... and cattle vaccinates normally occurs from 7 to 21 days after inoculation with arMP-12. While the serology and protective response induced by arMP-12 has been studied, little attention has been paid to the underlying molecular and genetic events occurring prior to the serologic immune response. To address this, we isolated RNA from whole blood of vaccinated calves over a time course of 21 days before and after vaccination with arMP-12. The time course RNAs were sequenced by RNASeq and bioinformatically analyzed. Our results revealed time-dependent activation or repression of numerous gene ontologies and pathways related to the vaccine induced immune response and its regulation. Additional bioinformatic analyses identified a correlative relationship between specific host immune response genes and protective immunity prior to the detection of protective serum neutralizing antibody responses. These results contribute an important proof of concept for identifying molecular and genetic components underlying the immune response to RVF vaccination and protection prior to serologic detection.
doi:10.1371/journal.pone.0147027 pmid:26783758 pmcid:PMC4718665 fatcat:okcbfsrk3nfhjaut4kmhd6bodm

Formal analytical solutions for the Gross–Pitaevskii equation

C. Trallero-Giner, Julio C. Drake-Perez, V. López-Richard, Joseph L. Birman
2008 Physica D : Non-linear phenomena  
1 2 ( x l 0 ) 2 , (4) where Λ = λ/l 0 ω, l 0 = /mω, and the value of λ ≥ 0 is restricted by Eq. (4).  ...  if λ 10 l 0 ω.  ... 
doi:10.1016/j.physd.2008.02.017 fatcat:g6r5hfk5yfdcvkpokscstcg3gq
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