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aGEM: an integrative system for analyzing spatial-temporal gene-expression information

Natalia Jiménez-Lozano, Joan Segura, José Ramón Macías, Juanjo Vega, José María Carazo
2009 Computer applications in the biosciences : CABIOS  
Motivation: The work presented here describes the 'anatomical Gene-Expression Mapping (aGEM)' Platform, a development conceived to integrate phenotypic information with the spatial and temporal distributions  ...  DAS is a client-server system in which a single client integrates information from multiple distributed servers. Results: The aGEM Platform provides information to answer three main questions.  ...  S Lindsay from Newcastle University for manuscript supervision and for contributing to this article with interesting ideas. Conflict of Interest: none declared.  ... 
doi:10.1093/bioinformatics/btp422 pmid:19592395 pmcid:PMC2752607 fatcat:ausedefbcfgdvdrtna6oh2jz4e

Mapping Mind-Brain Development: Towards a Comprehensive Theory

George Spanoudis, Andreas Demetriou
2020 Journal of Intelligence  
Awareness of mental processes is recycled with the changes in each cycle and drives their integration into the representational unit of the next cycle.  ...  Information entering these networks is available to awareness processes. Brain networks change along the four cycles, in precision, connectivity, and brain rhythms.  ...  Processing of verbally expressed categorical information is associated with the entire superior temporal gyrus, which is related to language understanding and it thus analyzes the "object" properties of  ... 
doi:10.3390/jintelligence8020019 pmid:32357452 pmcid:PMC7713015 fatcat:x33atvgzkzcpnl4dz2vg4dlvta

Activation of Two Osmotin-Like Protein Genes by Abiotic Stimuli and Fungal Pathogen in Transgenic Potato Plants

B. Zhu, THH. Chen, P. H. Li
1995 Plant Physiology  
A genomic clone (ApCEM2a-7) that contains two osmotin-like protein genes (OSML13 and OSML81) arranged in the same transcriptional orientation has been isolated.  ...  Restriction mapping and sequence analysis indicated that the two intronless genes correspond to the previously characterized pA13 and pA81 cDNAs. To study the  ...  We also thank the Central Service Laboratory of the Center for Gene Research and Biotechnology at Oregon State University for DNA sequencing. We are grateful to Dr. P.B.  ... 
doi:10.1104/pp.108.3.929 pmid:7630973 pmcid:PMC157442 fatcat:ckyp7bigcngpzcgb54trtr5clq

From first words to grammar in children with focal brain injury

Elizabeth Bates, Donna Thal, Doris Trauner, Judi Fenson, Dorothy Aram, Julie Eisele, Ruth Nass
1997 Developmental Neuropsychology  
Results are used to argue against innate localization of linguistic representations, and in favor of an alternative view in which innate regional biases in style of information processing lead to familiar  ...  Although there were no differences between left-vs. right-hemisphere injury per se on expressive language, children whose lesions include the left temporal lobe did show significantly greater delays in  ...  Gould, 1977) , with particular reference to the role that genes play in turning systems on and off at different points in the life span.  ... 
doi:10.1080/87565649709540682 fatcat:n5zk43b4vfhr5ourosflcwbxwy

ACNP 59th Annual Meeting: Poster Session II

2020 Neuropsychopharmacology  
In the current analysis, an initial dataset of 363 participants completed MRI scans within a)~2-weeks, b)~6-months, or c) both~2-weeks and~6-months post-trauma.  ...  The structure of human neural circuits is critical for neurocognitive processes that maintain healthy emotional function.  ...  To identify gene expression signatures related to mental illness status and survival rate, we performed differential gene expression analysis while controlling for RNA integrity scores.  ... 
doi:10.1038/s41386-020-00891-6 pmid:33279935 pmcid:PMC7735200 fatcat:5nfeakhcfnhpnjyuvli34vyxxq

Abstracts of the Twenty-Fifth Annual Meeting of The American Society of Primatologists

2002 American Journal of Primatology  
Abstracts / 61 value in planning establishment of an SPF colony.  ...  All calls were then analyzed for several acoustic and temporal features including call duration, bandwidth, and peak frequency.  ...  through observation rather than direct experience is an excellent method for low-cost information transfer.  ... 
doi:10.1002/ajp.1091 fatcat:pzys5ajm5fbcvizmrcj2mg2eqe

Mothers with intellectual disability, their experiences of maltreatment, and their children's attachment representations: a small-group matched comparison study

Pehr Granqvist, Tommie Forslund, Mari Fransson, Lydia Springer, Lene Lindberg
2014 Attachment & Human Development  
Among children of mothers with ID, a substantial minority (35%) had a secure and the vast majority (>80%) an organized attachment representation.  ...  We discuss possible implications of our findings for societal considerations regarding parenting and child attachment in the context of parental ID status.  ...  Kerstin Andersson for working with the data collection and to SUF Kunskapscentrum for support. Special thanks to the participants of the study, who often shared very difficult memories with us.  ... 
doi:10.1080/14616734.2014.926946 pmid:24931835 fatcat:honc4kgxnjhihmmbxx53ebnrpq

Peer presence elicits task-independent changes within and beyond the mentalizing network across children and adults [article]

Leslie Tricoche, Denis Pélisson, Léa Longo, Eric Koun, Alice Poisson, Jérôme Prado, Martine Meunier
2022 bioRxiv   pre-print
Rather, we observed the same task-independent changes for both numerosity and phonological comparisons.  ...  AbstractThere is ample behavioral evidence that others' mere presence can affect any behavior in human and non-human animals, generally facilitating the expression of mastered responses while impairing  ...  Acknowledgments We thank the CERMEP Primage MRI engineers Franck Lamberton, and Danielle Ibarrola for  ... 
doi:10.1101/2022.04.19.488718 fatcat:ztyu3a2eyngljj4dqfxyfjqpfe

The Evolutionary Origins of Friendship

Robert M. Seyfarth, Dorothy L. Cheney
2012 Annual Review of Psychology  
For personal use only.  ...  In horses, elephants, hyenas, dolphins, monkeys, and chimpanzees, some individuals form friendships that last for years. Bonds occur among females, among males, or between males and females.  ...  Oxytocin is associated with prosocial behaviors in female mammals, and the gene coding for its receptor, OXTR, is heavily expressed in the brains of female rodents (see Carter et al. 2008 for review)  ... 
doi:10.1146/annurev-psych-120710-100337 pmid:21740224 fatcat:x2qnqgv2lrh3henbpi45qqfpou

Abstracts

1996 Diabetologia  
Research Design and Methods: One hundred forty three consecutive diabetic sul~jects presenting for care between 1993-1995 were divided into three groups for purposes of evaluation.  ...  Patients with high skin temperatures unilaterally may be at risk for ulceration or fracture.  ...  Blood samples and information were collected March-August 1995 for all children with IDDM born 1977 or later. The HbA~ concentration was determined once and analyzed centrally.  ... 
doi:10.1007/bf00624797 fatcat:kn5cbym2u5fsrk3yv5b53yi6ui

POSTER SESSION 2

2015 Europace  
Calibrated integrated backscatter (cIB) was established as difference between pericardial and myocardial reflectivity.  ...  Results were tabulated for overall QoL and for each domain.  ...  Automated analysis of the multi lead rhythms showed 92% sensitivity for NSR, and 100% sensitivity for atrial flutter, and 92% for sinus bradycardia, when compared to the 12-lead ECGs.  ... 
doi:10.1093/europace/euv158 fatcat:ys4pkdd5vzh35bal6dl3ip2svm

Why do individuals with autism lack the motivation or capacity to share intentions?

Tony Charman
2005 Behavioral and Brain Sciences  
For example, it is only if a young child understands other persons as intentional agents that she can acquire and use linguistic symbols -because the learning and use of symbols requires an understanding  ...  Understanding intentions is foundational because it provides the interpretive matrix for deciding precisely what it is that someone is doing in the first place.  ...  ACKNOWLEDGMENTS We are grateful to Rob Whelan, Ruth Anne Rehfeldt, and Eric Fox for helpful comments.  ... 
doi:10.1017/s0140525x05260120 fatcat:5qdxsvwsrnaplpw2qxliqq6u6e

American Society of Nephrology

1988 Kidney International  
The expression of the single copy gene for this enzyme is known to be transcriptionally regulated, and transcription increases in kidney with administration of hormones and systemic acidosis in-vivo.  ...  The 5' flank revealed an HTF-Iike island associated with 41 potential methyfation sites which may be involved In selective gene expression.  ...  Cyclosporine (CyA) has greatly improved renal allograft survival and is now considered an integral part of the immunosuppressive regimen for transplant recipients.  ... 
doi:10.1038/ki.1988.20 fatcat:rjr4e7hjmrfmzedbffpifnsrvu

The four elementary forms of sociality: Framework for a unified theory of social relations

Alan P. Fiske
1992 Psychological review  
In addition to an array of inductive evidence from many cultures and approaches, the theory has been supported by ethnographic field work and 19 experimental studies using 7 different methods testing 6  ...  Surely this incessant expression of social status informs personal identity.  ...  With this set of four models, the relational models theory provides an integrative framework for a great deal of research and theory across the spectrum of core social science disciplines.  ... 
doi:10.1037//0033-295x.99.4.689 fatcat:x2um2kcbkjb5lj7d27cp6dpg6y

The four elementary forms of sociality: Framework for a unified theory of social relations

Alan P. Fiske
1992 Psychological review  
In addition to an array of inductive evidence from many cultures and approaches, the theory has been supported by ethnographic field work and 19 experimental studies using 7 different methods testing 6  ...  Surely this incessant expression of social status informs personal identity.  ...  With this set of four models, the relational models theory provides an integrative framework for a great deal of research and theory across the spectrum of core social science disciplines.  ... 
doi:10.1037/0033-295x.99.4.689 pmid:1454904 fatcat:y7hkrhltg5fo7c2ormq2q4aqbu
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