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We find that the mixed maximally entangled states exist and prove that the form of the mixed maximally entangled states is unique in terms of the entanglement of formation. Moreover, even if the entanglement is quantified by other entanglement measures, this conclusion is still proven right. This result is a supplementary to the generally accepted fact that all maximally entangled states are pure. These states possess important properties of the pure maximally entangled states, for example,arXiv:0906.5445v2 fatcat:6czlopsccbctpk634yzigxwkzu
more »... e states can be used as a resource for faithful teleportation and they can be distinguished perfectly by local operations and classical communication.
We provide a class of six-qubit states for three-qubit perfect teleportation. These states include the six-qubit cluster states as a special class. We generalize this class of six-qubit states to 2n-qubit pure states for n-qubit teleportation, n >=1. These states can be also used for 2n bit classical information transmission in dense coding.doi:10.1088/1751-8113/45/40/405303 fatcat:5g53zh4ruzadlmkwx635oushfm
Next-generation sequencing has allowed identification of millions of somatic mutations in human cancer cells. A key challenge in interpreting cancer genomes is to distinguish drivers of cancer development among available genetic mutations. To address this issue, we present the first web-based application, consensus cancer driver gene caller (C3), to identify the consensus driver genes using six different complementary strategies, i.e., frequency-based, machine learning-based, functionaldoi:10.1016/j.gpb.2018.10.004 pmid:31465854 pmcid:PMC6818389 fatcat:dirl422q3ratrjni2wi63gt4me
more »... ed, clustering-based, statistics model-based, and network-based strategies. This application allows users to specify customized operations when calling driver genes, and provides solid statistical evaluations and interpretable visualizations on the integration results. C3 is implemented in Python and is freely available for public use at http://drivergene.rwebox.com/c3.
It is well known that the fair-sampling loophole in Bell test opened by the selection of the state to be measured can lead to post-quantum correlations. In this paper, we make the selection of the results after measurement, which opens the fair-sampling loophole too, and thus can lead to post-quantum correlations. This kind of result-selection loophole can be realized by pre-and post-selection processes within the "two-state vector formalism", and a physical simulation of Popescu-Rohrlich (PR)doi:10.1038/srep28351 pmid:27329203 pmcid:PMC4916437 fatcat:j43ibvvlk5d53cgro2xh7qocti
more »... ox is designed in linear optical system. The probability distribution of the PR has a maximal CHSH value 4, i.e. it can maximally violate CHSH inequality. Because the "two-state vector formalism" violates the information causality, it opens the locality loophole too, which means that this kind of results selection within "two-state vector formalism" leads to both fair-sampling loophole and locality loophole, so we call it a comprehensive loophole in Bell test. The comprehensive loophole opened by the results selection within "two-state vector formalism" may be another possible explanation of why postquantum correlations are incompatible with quantum mechanics and seem not to exist in nature.
We investigate the time evolution of the entanglement of assistance when one subsystem undergoes the action of local noisy channels. A general factorization law is presented for the evolution equation of entanglement of assistance. Our results demonstrate that the dynamics of the entanglement of assistance is determined by the action of a noisy channel on the pure maximally entangled state, in which the entanglement reduction turns out to be universal for all quantum states entering thedoi:10.1103/physreva.81.042312 fatcat:4r7xabqldjbofcrzfyrizvccqi
more »... This single quantity will make it easy to characterize the entanglement dynamics of entanglement of assistance under unknown channels in the experimental process of producing entangled states by assisted entanglement.
Dong Xia, Zong-lin Li, Lei Ren, and Ming-ming Wang were responsible for construct Xenograft tumor formation assay. ... Wang-sheng Chen, Zheng-chuan Hu, and Guo-ping Yi were jointly involved in extracting data and writing the manuscript. ...doi:10.1042/bsr20180441 pmid:29700213 pmcid:PMC6689104 fatcat:5egyfzkbuvcozg4kmh44mvmucu
doi:10.1371/journal.pcbi.0020074 pmid:16839196 pmcid:PMC1487180 fatcat:zdesiosqrjhw5fnueb7247wuo4
E60, o678-o680 [https://doi.org/10.1107/S1600536804006671] 4′-Acetylbenzo-15-crown-5 2-naphthyloxyacetylhydrazone Tai-Bao Wei, Yan-Qing Zhou, You-Ming Zhang and Guo-Geometry. All e.s.d.' ...doi:10.1107/s1600536804006671 fatcat:rn3ipb2dsje7lajv2k4lrfnl4e
We investigate the general characters of fully entangled fraction for quantum states. The fully entangled fraction of Isotropic states and Werner states are analytically computed.doi:10.1088/1751-8113/43/27/275203 fatcat:wa2nyabubng5lkbk4nyi5esr3a
Aim: Imrecoxib is a novel and moderately selective COX-2 inhibitor. The aim of the present in vitro investigation was to study the formation of the major metabolite 4'-carboxylic acid imrecoxib (M2) and identify the enzyme(s) involved in the reaction. Methods: The formation of M2 was studied in rat liver cytosol in the absence or presence of liver microsomes. The formed metabolite was identified and quantified by LC/MS n . In addition, to characterize the cytochrome P450 (CYP) isozymes involveddoi:10.1111/j.1745-7254.2006.00312.x pmid:16539853 fatcat:53dkankbsjcbtajpde2afopwca
more »... in M2 formation, the effects of typical CYP inhibitors (such as ketoconazle, quinine, α-naphthoflavone, methylpyrazole, and cimetidine) on the formation rate of M2 were investigated. Results: The formation of M2 from 4'hydroxymethyl imrecoxib (M4) was completely dependent on rat liver microsomes and NADPH. Enzyme kinetic studies demonstrated that the formation rate of M2 conformed to monophasic Michaelis-Menten kinetics. Additional experiments showed that the formation of M2 was induced significantly by dexamethasone and lowered by ketoconazole strongly and concentration-dependently. By comparison, other CYP inhibitors, such as α-naphthoflavone, cimetidine, quinine, and methylpyrazole had no inhibitory effects on this metabolic pathway. Conclusion: These biotransformation studies of M4 and imrecoxib in rat liver at the subcellular level showed that the formation of M2 occurs in rat liver microsomes and is NADPH-dependent. The reaction was mainly catalyzed by CYP 3A in untreated rats and in dexamethasone-induced rats. Other CYP, such as CYP 1A, 2C, 2D, and 2E, seem unlikely to participate in this metabolic pathway.
The smart city management platform based on GIS provides a powerful data and decision support for the construction of underground projects and to avoid the occurrence of ground disaster caused by excavation. In view of the project problems of surface substance caused by the excavation of urban tunnel, the data management process of urban tunnel excavation is established based on the GIS management technology, and combined with the characteristic of four dimensional data in the process of urbandoi:10.12783/dtmse/ictim2017/9954 fatcat:wrnyymcwmjccvfyp4acl7a6ye4
more »... unnel construction, the method of storing time dimension + dynamic and static data in the process of urban tunnel construction is designed, the standard database of surface substance early warning is set up and the predicted module of surface substance caused by excavation of urban tunnel under different geological conditions is developed, and by the expected module the corresponding storage data and calculation model are called to predict the surface subsidence caused by tunnel excavation and determine the influence range of the excavation disturbance, and the analysis results are fed back to the data management of GIS platform, and this will provide technical support for decision makers by comparing with the corresponding standards. Through the analysis of the actual case of Qingdao city tunnel excavation, it provides technical support for preventing the occurrence of disasters during the tunnel excavation.
Flexor retinaculum transection is a routine surgical treatment for carpal tunnel syndrome, yet the biomechanical and clinical sequelae of the procedure remain unclear. We investigated the effects of flexor retinaculum release on carpal tunnel structural compliance using cadaveric hands. Methods: The flexor retinaculum was incrementally and sequentially released with transections of 25, 50, 75, and 100 % of the transverse carpal ligament, followed by the distal aponeurosis and then thedoi:10.1186/s13018-016-0380-3 pmid:27074707 pmcid:PMC4831089 fatcat:iupckuhrj5egdcwonlduok6oqy
more »... al fascia. Paired outward 10 N forces were applied to the insertion sites of the transverse carpal ligament at the distal (hamate-trapezium) and proximal (pisiform-scaphoid) levels of the carpal tunnel. Carpal tunnel compliance was defined as the change in carpal arch width normalized to the constant 10 N force. Results: With the flexor retinaculum intact, carpal tunnel compliance at the proximal level, 0.696 ± 0.128 mm/N, was 13.6 times greater than that at the distal level, 0.056 ± 0.020 mm/N. Complete release of the transverse carpal ligament was required to achieve a significant gain in compliance at the distal level (p < 0.05). Subsequent release of the distal aponeurosis resulted in an appreciable additional increase in compliance (43.0 %, p = 0.052) at the distal level, but a minimal increase (1.7 %, p = 0.987) at the proximal level. Complete flexor retinaculum release provided a significant gain in compliance relative to transverse carpal ligament release alone at both proximal and distal levels (p < 0.05). Conclusions: Overall, complete flexor retinaculum release increased proximal compliance by 52 % and distal compliance by 332 %. The increase in carpal tunnel compliance with complete flexor retinaculum release helps explain the benefit of carpal tunnel release surgery for patients with carpal tunnel syndrome.
During drilling, how to achieve the aim of deviation control and fast drilling effectively is a common technique issue. Though there are some anti-deviation and well straightening methods at present in drilling fields, most of them have their disadvantages, such as decreasing the weight on bit (WOB) and the rate of penetration (ROP). These drilling methods can't achieve the aim of deviation control and fast drilling economically and effectively in high dip, fractured, fault zones, and otherdoi:10.4028/www.scientific.net/amr.339.611 fatcat:rhhersgyvvhixlpiipa3mp6xku
more »... rmal formations. . Automatic Vertical Drilling System (AVDS) is a Mechanical-Electrical-Hydraulic integrated drilling tool, and it is also an intelligent drilling system. As an advanced technology, the AVDS is a great breakthrough in deviation control and fast drilling. According to the result of theoretical analysis and oilfield applications, the AVDS can not only increase the weight on bit and improve the rate of penetration greatly, but also can guarantee improved well bore quality. And perfect borehole quality is an important premise of subsequent operation while drilling. Φ311 Automatic Vertical Drilling System (Φ311 AVDS) belongs to the relative-static-effective AVDS, it has been experimented effectively and successfully in Xinjiang oilfield. By the results of the experiments, the indexes of the Φ311 AVDS have met the design requirements and achieved vertical and fast drilling aim in high dip formations. The paper aims to introduce the characteristics, operating principles and matching technologies of the Φ311 AVDS.
The hybrid quantum network, a universal form of quantum network which is aimed for quantum communication and distributed quantum computation, is that the quantum nodes in it are realized with different physical systems. This universal form of quantum network can combine the advantages and avoid the inherent defects of the different physical system. However, one obstacle standing in the way is the compatible photonic quantum interface. One possible solution is using non-degenerate, narrow-band,arXiv:1707.03178v1 fatcat:5k2hwik3pjax7f6hv36x4nwfiu
more »... ntangled photon pairs as the photonic interface. Here, for the first time, we generate nondegenrate narrow-band polarization-entangled photon pairs in cavity-enhanced spontaneous parametric down-conversion process. The bandwidths and central wavelengths of the signal and idler photons are 9 MHz at 935 nm and 9.5 MHz at 880 nm, which are compatible with trapped ion system and solid-state quantum memory system. The entanglement of the photon source is certified by quantum state tomography, showing a fidelity of 89.6% between the generated quantum state with a Bell state. Besides, a strong violation against Bell inequality with 2.36+/-0.03 further confirms the entanglement property of the photon pairs. Our method is suitable for the hybrid quantum network and will take a big step in this field.
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