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Zhenwu decoction for chronic heart failure

Qi Tang, Yuanping Wang, Kuangyi Li
2018 Medicine  
Zhenwu decoction (ZWD) has been widely adopted to clinical practice for patients with CHF.  ...  [9] Zhenwu decoction (ZWD), as a well-known CHM in CHF treatment in China, is composed of Cinnamomi Ramlus, Zingibers Rhizoma Recens, Poria, Aconiti Lateralis Radix Praeparata, and Atractylodis Macrocephalae  ... 
doi:10.1097/md.0000000000011559 pmid:30024553 pmcid:PMC6086473 fatcat:bgqwrps6pzhrpfxwsattfl6aqm

Evaluation of Zhenwu Decoction Effects on CYP450 Enzymes in Rats Using a Cocktail Method by UPLC-MS/MS

Li-li Hong, Qian Wang, Ya-ting Zhao, Sheng Zhang, Kai-qi Zhang, Wei-dong Chen, Can Peng, Li Liu, Hong-song Wang
2020 BioMed Research International  
This thesis is aimed at shedding light on the effects of the Zhenwu decoction (ZWD) on the activities and mRNA expressions of seven CYP450 isoenzymes.  ...  The authors thank Qian Wang for assisting with the sample detection and data processing of this experiment; Professors Wei-dong Chen, Can Peng, and Li Liu for providing the platform for this experiment  ...  Introduction The Zhenwu decoction (ZWD), one of the classic prescriptions for the treatment of Yang deficiency, was recorded in the "Treatise on Febrile Diseases" by Zhang Zhongjing.  ... 
doi:10.1155/2020/4816209 pmid:32461991 pmcid:PMC7240782 fatcat:ubb4qpbs2zgxhjllnipeteoyxy

Renoprotective effect of Zhenwu decoction against renal fibrosis by regulation of oxidative damage and energy metabolism disorder

Shasha Li, Xue Xiao, Ling Han, Yiming Wang, Guoan Luo
2018 Scientific Reports  
Zhenwu decoction (ZWD) is a promising traditional Chinese prescription against renal fibrosis, while its underlying mechanism remains unclear.  ...  Zhenwu decoction (ZWD) is a classical TCM prescription consisting of Aconiti Lateralis Radix Praeparata, Poria cocos, Radix Paeoniae Alba, Ginger and Rhizoma Atractylodis Macrocephalae.  ... 
doi:10.1038/s41598-018-32115-9 pmid:30279506 pmcid:PMC6168532 fatcat:ccomu5dtyvajbbhp53xvo3ac64

Evaluation of the Influence of Zhenwu Tang on the Pharmacokinetics of Digoxin in Rats Using HPLC-MS/MS

Chao Li, Dahu Liang, Yanhao Liu, Chaozhuang Shen, Xiaohu Wang, Bin Yang, Xianghong Li, Weijia Wang, Maodi Xu, Zhichen Pu, Hua Hu, Zijing Wu (+3 others)
2021 Evidence-Based Complementary and Alternative Medicine  
Up to date, several studies have shown that the ginger and Poria extracts in Zhenwu Tang (ZWT) affect P-gp transport activity.  ...  In addition, Li et al.  ...  Materials and Methods Preparation of Zhenwu Tang.  ... 
doi:10.1155/2021/2673183 pmid:34616474 pmcid:PMC8490036 fatcat:yiwaickr4zhr3j7w2wkjjjvjwm

HIV-associated memory B cell perturbations

Zhiliang Hu, Zhenwu Luo, Zhuang Wan, Hao Wu, Wei Li, Tong Zhang, Wei Jiang
2015 Vaccine  
Memory B-cell depletion, hyperimmunoglobulinemia, and impaired vaccine responses are the hallmark of B cell perturbations inhuman immunodeficiency virus (HIV) disease. Although B cells are not the targets for HIV infection, there is evidence for B cell, especially memory B cell dysfunction in HIV disease mediated by other cells or HIV itself. This review will focus on HIVassociated phenotypic and functional alterations in memory B cells. Additionally, we will discuss the mechanism underlying
more » ... se perturbations and the effect of anti-retroviral therapy (ART) on these perturbations.
doi:10.1016/j.vaccine.2015.04.008 pmid:25887082 pmcid:PMC4420662 fatcat:7ccm2pqrrbbexechnkk2kxojjy

Parallel Computing Based Dynamic Programming Algorithm of Track-before-Detect

Qiang Guo, Zhenwu Li, Wenming Song, Wenyu Fu
2018 Symmetry  
The conventional dynamic programming-based track-before-detect (DP-TBD) methods are usually intractable in multi-target scenarios. The adjacent targets may interfere with each other, and the computational complexity is increased with the number of targets. In this paper, a DP-TBD method using parallel computing (PC-DP-TBD) is proposed to solve the above problems. The search region of the proposed PC-DP-TBD is divided into several parts according to the possible target movement direction. The
more » ... rgy integration is carried out independently and parallel in each part. This contributes to reducing the computational complexity in each part, since the divided search region is smaller than the whole one. In addition, the target energy can only be integrated adequately in the part in which the search direction matches the target movement. This is beneficial to improve the ability to detect the targets with various movement directions in different parts with different search directions. The solution to the problem of the adjacent targets interfering with each other is discussed. The procedure of the parallel computing in the proposed PC-DP-TBD is presented in detail. Simulations are conducted to verify the superiority of the proposed PC-DP-TBD in terms of detection probability and computational complexity.
doi:10.3390/sym11010029 fatcat:gmha5mzg7zd23c7ixrlaobvg2m

Congenital pulmonary airway malformation mimicking lung cancer

Ying Zhao, Yongxiang Zhang, Qi Leng, Zhenwu Li, Peng Pang, Xiaoli Qi
2019 Medicine  
Congenital pulmonary airway malformation (CPAM) is a rare developmental deformity of the lower respiratory tract. The disease occurs more in newborns. However, on rare occasions, CPAM can be found in adults. Radiologic features of CPAM include cystic or solid mass pattern. In an elderly patient, CPAM can be easily misdiagnosed as lung cancer. A 66-year old woman was admitted with complaints of chronic cough, expectoration. Her past history was unremarkable with no history of tuberculosis or
more » ... ing. Physical examination was normal. Computerized tomography of the chest showed an irregular cystic lesion in right lower lobe. Histopathological results confirmed the diagnosis of CPAM. The right pulmonary wedge resection was performed via thoracoscopic surgery. On follow up 1 year later, the patient is asymptomatic. CPAM is rare in adults, and imaging cannot accurately distinguish CPAM from thin-walled cystic lung cancer. Hence, histopathology is mandatory to confirm the diagnosis.
doi:10.1097/md.0000000000016057 pmid:31192965 pmcid:PMC6587640 fatcat:hhxkdwl5fvcolcvcncvuwr3sdy

Identification of biomarkers associated with synovitis in rheumatoid arthritis by bioinformatics analyses

Zhaoyan Li, Meng Xu, Ronghang Li, Zhengqing Zhu, Yuzhe Liu, Zhenwu Du, Guizhen Zhang, Yang Song
2020 Bioscience Reports  
, Xu Meng, and Yuzhe Liu performed the analysis work; Zhenwu Du, Ronghang Li, and Zhengqing Zhu contributed to the data analysis; Guizhen Zhang and Zhaoyan Li organized, designed, and wrote the paper.  ... by guest on 27 August 2020Authors' ContributionsGuizhen Zhang and Yang Song designed and supervised the study; Zhaoyan Li  ... 
doi:10.1042/bsr20201713 pmid:32840301 pmcid:PMC7502692 fatcat:rffcn5i6yvd4nbtwwdifij3oty

A Mononuclear Iron Thiolate Complex with N-Heterocyclic Carbene Ligation

Shangzhao Li, Zhenwu Ouyang, Junjie Zou, Dongyang Wang, Bin Xu, Liang Deng
2022 Huaxue xuebao  
摘要 含硫配体的低价铁物种被认为是固氮酶配位活化氮气时的活性金属物种, 但与之相关的含硫配体的单核型低价 铁配合物的合成非常具有挑战性, 报道很少. 我们发现通过含氮杂环卡宾配体的三配位一价铁配合物(IMes) 2 FeBr 反应, 生成 N(SiMe 3 ) 3 , 转换数(TON)可达 87.
doi:10.6023/a22010038 fatcat:szc6snxzrvfxzbkprxzshjil2y

Proteomics Analysis of Alfalfa Response to Heat Stress

Weimin Li, Zhenwu Wei, Zhihong Qiao, Zinian Wu, Lixiang Cheng, Yuyang Wang, Rizwan H. Khan
2013 PLoS ONE  
The proteome responses to heat stress have not been well understood. In this study, alfalfa (Medicago sativa L. cv. Huaiyin) seedlings were exposed to 25uC (control) and 40uC (heat stress) in growth chambers, and leaves were collected at 24, 48 and 72 h after treatment, respectively. The morphological, physiological and proteomic processes were negatively affected under heat stress. Proteins were extracted and separated by two-dimensional polyacrylamide gel electrophoresis (2-DE), and
more » ... ally expressed protein spots were identified by mass spectrometry (MS). Totally, 81 differentially expressed proteins were identified successfully by MALDI-TOF/TOF. These proteins were categorized into nine classes: including metabolism, energy, protein synthesis, protein destination/storage, transporters, intracellular traffic, cell structure, signal transduction and disease/defence. Five proteins were further analyzed for mRNA levels. The results of the proteomics analyses provide a better understanding of the molecular basis of heat-stress responses in alfalfa.
doi:10.1371/journal.pone.0082725 pmid:24324825 pmcid:PMC3855785 fatcat:ogtatiaxmjhmjiwp76nwyzedi4

Bone Mesenchymal Stem Cells Contributed to the Neointimal Formation after Arterial Injury

Mincai Li, Suqin Li, Liangzhu Yu, Jiliang Wu, Tonghui She, Yaping Gan, Zhenwu Hu, Wenli Liao, Hongli Xia, Giovanni Camussi
2013 PLoS ONE  
Objectives: Recent findings suggest that in response to repair-to-injury bone marrow mesenchymal stem cells (BMSCs) participate in the process of angiogenesis. It is unclear what role BMSCs play in the structure of the vessel wall. In present study, we aimed to determine whether BMSCs had the capacity of endothelial cells (ECs). Methods: BMSCs were separated and cultured. FACS and RT-PCR analysis confirmed the gene expression phenotype. The capacity of migration and adhesion and the
more » ... re of BMSCs were examined. The effect of BMSCs transplantation on the vascular repair was investigated in a murine carotid artery-injured model. Results: BMSCs could express some markers and form the tube-like structure. The migration and adhesion capacity of BMSCs increased significantly after stimulated. In addition, BMSCs had the intact cell junction. In vivo the local transfer of BMSCs differentiated into neo-endothelial cells in the injury model for carotid artery and contributed to the vascular remodeling. Conclusion: These results showed that BMSCs could contribute to neointimal formation for vascular lesion and might be associated with the differentiation into ECs, which indicated the important therapeutic implications for vascular diseases.
doi:10.1371/journal.pone.0082743 pmid:24349351 pmcid:PMC3857273 fatcat:75k45heth5c6ndic3a5tx4gccq

Optical fiber ultrasonic sensor networks based on WDM and TDM

Zhenwu Guo, Weixiang Li, Tiegen Liu
2011 Journal of Physics, Conference Series  
An optical fiber sensor network for ultrasonic measurement based on wavelength division multiplexing (WDM) and time division multiplexing (TDM) technology is presented. Each of the sensor probes is an optical fiber extrinsic Fabry-Perot interferometer (EFPI) which is composed of the fiber's end face and the aluminum thin diaphragm. The sensors are arranged in different wavelength domains formed by a wavelength division multiplexer. Each wavelength division multiplexer, with a group of the
more » ... s, is connected to one of the output ports of optical switch to realize TDM. The signal of each sensor is exported sequentially from a tunable narrowband optical filter (TNOF) that queries every sensor though scanning mode. The principle of the phenomenon of phase induced signal fade in interferometric fiber-optic sensors is also analyzed. Nicely, the detection method above implements the operation of anti-phase induced signal fade detection. The system is interrogated by broadband light source. The scanning range of TNOF is full of the bandwidth of the light source. The result of experiment in water show that the sensor sensitivity reaches -162dB(0dB=1rad/µPa), the Pa), the frequency response range is from 10KHz to 5 MHz. The number of multiplexing sensors based on WDM and TDM reaches to 64.
doi:10.1088/1742-6596/276/1/012125 fatcat:fdrrstw54ba6nl3gtmu37mcwp4

Application of harmonic diffraction in infrared

Qiang Sun, Zhaoqi Wang, Wei Quan, Fengyou Li, Yongjun Xie, Zhenwu Lu, Bo Chen, Zhicheng Weng, Jose M. Sasian, Yongtian Wang
2002 Optical Design and Testing  
However , the wavelength bandwidths of the diffraction efficiency around central wave length of lOjtm and 4tm are lied in spectrum regions of thermal infrared and mid-infrared.  ... 
doi:10.1117/12.471678 fatcat:ir2uex3hlzerhcj4lj2cgpajgq

Rigorous Plasma Microbiome Analysis Method Enables Disease Association Discovery in Clinic

Zhenwu Luo, Alexander V. Alekseyenko, Elizabeth Ogunrinde, Min Li, Quan-Zhen Li, Lei Huang, Betty P. Tsao, Diane L. Kamen, Jim C. Oates, Zihai Li, Gary S. Gilkeson, Wei Jiang
2021 Frontiers in Microbiology  
FUNDING This work was supported by grants from the National Institutes of Health: R01 AI128864 and supplemental grant (Jiang), R01 CA213290 (Li), R01 AR071410 and R01 AR071947 (Tsao), P60 AR062755 (Gilkeson  ... 
doi:10.3389/fmicb.2020.613268 pmid:33488555 pmcid:PMC7820181 fatcat:eydptyqflzex5o22qbl4ukezr4

Corrosion Law of Metal Pipeline in Tahe Oilfield and Application of New Materials

Xiaolong Shi, Zhi Zhang, Lanjie Wu, Xincai Li, Zhenwu Zhang
2021 Coatings  
(Zhenwu Zhang); resources, X.S. and L.W.; data curation, L.W. and Z.Z. (Zhi Zhang); writing-original draft preparation, X.S. and Z.Z. (Zhenwu Zhang); writing-review and editing, Z.Z.  ...  In 2014, Li Dapeng et al. studied the effect of H2S concentration on the corrosion behavior of pipeline steel under the coexistence of H2S and CO2.  ... 
doi:10.3390/coatings11111269 fatcat:5clos22xhrdj5ago2b54u7gqza
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