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A Tactile Sensor Decoupling Process
2018
Sensors
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An improved hybrid homotopy method is proposed to decouple the multi-input model of tactile sensors. The time-embedded homotopy algorithm is proved to be very suitable for solving the problem. Three tracking factors that control the efficiency of the algorithm are studied: tracking operator, stepsize, and accuracy. Trust region methods are applied to track the zero paths instead of the traditional differential algorithm, and a periodic sampling method is proposed to improve the efficiency of
doi:10.3390/s18103515
fatcat:pqrqer4r6jdefmhvuhy2zsyfyi
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... algorithm. Numerical experiments show that both the robustness and accuracy have received a huge boost after the hybrid algorithm is applied.
The Southwest China Flood of July 2018 and Its Causes
2019
Atmosphere
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Excessive rainfall was observed over Southwest China in July 2018, leading to floods in several major tributaries of the Yangtze River and landslide and debris flow in the neighboring provinces. The rainfall during 7–11 July was unusually heavy and broke the record that can be traced back to 1961. The occurrence of the excessive rain can be attributed to the anomalous convection over the western North Pacific and the presence of a mid-latitude Rossby wave train. On one hand, the convection over
doi:10.3390/atmos10050247
fatcat:dywjgyckyjcv3jg2raqcurtcmy
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... the western North Pacific was anomalously strong in July 2018, and it could have excited the negative phase of the Pacific–Japan pattern and led to a northwestward shift of the western Pacific subtropical high. Hence, the water vapor transport toward inland China including Southwest China was enhanced, providing a favorable moisture environment for precipitation. On the other hand, a mid-latitude Rossby wave train was observed to propagate from Northern Europe towards East Asia, which was conducive to anomalous ascending motion over Southwest China via warm advection and differential vorticity advection, creating a favorable dynamical condition for precipitation. As a result, the combination of the two effects mentioned above led to the occurrence of the flood over Southwest China in July 2018.
On Boundedness and Attractiveness of Nonlinear Switched Delay Systems
2013
Abstract and Applied Analysis
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This paper is concerned with the boundedness and attractiveness of nonlinear switched delay systems whose subsystems have different equilibria. Some sufficient conditions which can guarantee the system's boundedness are obtained. In addition, we work out the region where the solution will remain and furthermore the relationship between the initial function and the bounded region. Based on the new concept of attractor with switching laws, we show that the nonlinear switched delay system is attractive and then obtain the attractive region.
doi:10.1155/2013/713847
fatcat:boxb3btsq5hitkethweawo3ipq
Fermented Soybean Meal Affects the Reproductive Performance and Oxidative Status of Sows, and the Growth of Piglets
2021
Animals
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This study aimed to investigate the effect of the fermented soybean meal on the reproductive performance, oxidative stress and colostrum composition of sows, and the growth performance of their progeny. A total of 44 sows were allotted to four dietary groups (n = 11/group). The dietary groups included the basal diet group (control) and the treatment groups in which soybean meal in the basal diet was replaced with 2%, 4%, and 6% fermented soybean meal, respectively. The experimental diets were
doi:10.3390/ani11030597
pmid:33668322
pmcid:PMC7996358
fatcat:bgzgnvouifaazpadfoucwim364
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... d to the sows from the 78th day of gestation to the 21st day of lactation. Replacing soybean meal in the basal maternal diet with the fermented soybean meal decreased the levels of malondialdehyde, cortisol, and 8-iso-prostaglandinF2α in the serum of sows and increased the average weight of piglets on the 14th day and the 21st day after birth. The activity of superoxide dismutase in the serum of sows was increased in the group with 4% fermented soybean meal on the 17th day of lactation. The levels of estrogen and growth factors in the serum of sows were enhanced in the group with 6% fermented soybean meal. In the colostrum, the levels of the protein and the immunoglobulin G were enhanced in the group with 4% fermented soybean meal. In conclusion, replacing the soybean meal in the basal maternal diet with the fermented soybean meal attenuates the oxidative stress status of the gestational and lactational sows, and enhances the average weight of their offspring.
The record‐breaking heat wave of June 2019 in Central Europe
2020
Atmospheric Science Letters
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ORCID Lin Wang https://orcid.org/0000-0002-3557-1853 Yuyun Liu https://orcid.org/0000-0002-0826-4663 ...
Meanwhile, the geopotential height anomalies averaged during the two heat waves ( Figure S4a and b) quite resemble the BBC pattern (e.g., Figure 3a in Xu et al., 2020) . ...
This wave-like pattern is quite similar to the negative phase of a recently identified teleconnection pattern along the summertime polar front jet, the British-Baikal Corridor (BBC) pattern (Xu et al. ...
doi:10.1002/asl.964
fatcat:fq2fsecogbh5takg7ez7557dky
A model of mucopolysaccharidosis type IIIB in pigs
2018
Biology Open
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Mucopolysaccharidosis type IIIB (MPS IIIB) is a rare genetic disorder caused by loss-of-function mutations in the NAGLU gene. Pigs are an ideal large animal model for human diseases; however, a porcine model of MPS IIIB has not been reported. We have previously generated a heterozygous NAGLU-deficient (NAGLU +/-) Large White boar via a transgenic approach. Here we characterized phenotypes of the F 1 offspring of this founder to establish a pig model for MPS IIIB. qRT-PCR revealed that the NAGLU
doi:10.1242/bio.035386
fatcat:ydec6nrtxnezznbni7qydv7u7e
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... expression level was significantly decreased in a variety of tissues in NAGLU +/− pigs. ELISA assays showed obvious deficiency of NAGLU and higher (P<0.05) glycosaminoglycan levels in multiple tissues from NAGLU +/− pigs. NAGLU +/− pigs grew at a significantly (P<0.05) slower rate than control animals (NAGLU +/+ ). Death, mostly sudden death, occurred at all ages in NAGLU +/− pigs, most of which died within two years. Necropsy findings included pleural adhesions, lung shrinkage and abnormalities in the pericardium and mild hepatomegaly in NAGLU +/− pigs. Notable pathological changes were observed in the sections of brain, liver, spleen and kidney from NAGLU +/− pigs. Brain atrophy, ventriculomegaly, cerebellar atrophy and abnormalities in the intracerebral capsule, parietal lobes and the thalamus were also evident in NAGLU +/− pigs. Together, NAGLU +/− pigs show typical symptoms of human MPS IIIB patients and thus represent a novel large animal model for the disease. This article has an associated First Person interview with the first author of the paper.
Structural Changes in the Pacific–Japan Pattern in the Late 1990s
2019
Journal of Climate
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The Pacific-Japan (PJ) pattern, also known as the East Asia-Pacific pattern, is a teleconnection that significantly influences the East Asian summer climate on various time scales. Based on several reanalysis and observational datasets, this study suggests that the PJ pattern has experienced a distinct three-dimensional structural change in the late 1990s. Compared with those during 1979-98, the PJ pattern shifts eastward by approximately 208 during 1999-2015, and the intensity of its
doi:10.1175/jcli-d-18-0123.1
fatcat:kjsb6fnydjhvlffbortb5mwwfi
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... structure in the extratropics weakens significantly. As a result, its influences on the summer rainfall along the mei-yu band are weakened after the late 1990s. These observed changes can be attributed to three reasons. First, the location where the PJ pattern is excited shifts eastward. Second, the easterly shear of the background wind is very weak around the source region of the PJ pattern after the late 1990s, which prevents the convection-induced baroclinic mode from converting into barotropic mode and thereby from propagating into the extratropics. Third, the PJ patterninduced rainfall anomalies are weak along the mei-yu band after the late 1990s. As a result, their feedbacks to the PJ pattern become weak and play a considerably reduced role in maintaining the structure of the PJ pattern in the midlatitudes. In contrast, the eddy energy conversion from the basic flow efficiently maintains the PJ pattern before and after the late 1990s and thereby contributes little to the observed change.
The Corrosion Resistance and Mechanism of AT13/Fe-Based Amorphous Composite Coatings
2021
Micromachines
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Due to high strength, high wear resistance and high corrosion resistance, the amorphous metallic glasses were investigated widely. In the present study, the corrosion resistance of amorphous coating and composite coatings with various proportions of AT13 (Al2O3–13 wt.% TiO2) ceramic as additions in 3.5 wt.% NaCl solution were studied. The corrosion resistance was improved obviously as the addition of AT13, and when the content of AT13 was 15 wt.%, the composite coating had the lowest corrosion
doi:10.3390/mi13010056
pmid:35056221
pmcid:PMC8781569
fatcat:yu4ysvdyczexhavhyzb7bgv4ci
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... urrent density (1.75 × 10−6 A cm−2) and the highest corrosion potential (−411 mV), which was 5.14 × 10−5 A cm−2 and −580 mV for Fe-based metallic glassy coating, respectively. The corrosion mechanism was proposed according to the long-time immersion corrosion test.
Detection of Ascorbic Acid Using Green Synthesized Carbon Quantum Dots
2019
Journal of Sensors
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In this work, carbon quantum dots (CQDs) were synthesized by microwave irradiation and were electropolymerized on glassy carbon electrode (GCE) to establish an electrochemical sensor for the selective detection of ascorbic acid (AA). Electrochemical behaviors of the prepared sensor were investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS). Herein, two wide linear responses were obtained in ranges of 0.01-3 mM and 4-12 mM
doi:10.1155/2019/9869682
fatcat:6urbxac57jaqdgblpe4dkoslnq
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... with a low detection limit of 10 μM to AA. High sensitivities (44.13 μA-1 μM-1 cm-2, 9.66 μA-1 μM-1 cm-2, respectively) corresponding to the linear ranges were also achieved. In addition, the electrochemical sensor exhibited good selectivity and robust anti-interference ability toward AA in the presence of dopamine (DA) and uric acid (UA). These results showed that this sensor can be used as a promising tool to detect AA in real complex systems.
Differences between images of large adenoma and protruding type of gallbladder carcinoma
2013
Oncology Letters
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The aim of this study was to investigate the differences between images of large adenoma of the gallbladder and the protruding type carcinoma of the gallbladder. A retrospective study was performed on 130 patients who underwent cholecystectomy or biopsy for gallbladder polypoid lesions larger than 10 mm; among them, 20 patients were malignant and 110 patients were benign. Patients' details including ultrasonography (US), computed tomography (CT) and magnetic resonance (MR) findings were
doi:10.3892/ol.2013.1248
pmid:23760294
pmcid:PMC3678592
fatcat:ydemlljz7zchdcntbp6ybh3kau
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... . All patients whose lesions were >15 mm by US, had CT or MR scans to further determine the nature of the lesion; two patients who were suspected to have a malignant lesion due to their large tumor size were benign by histological examination. Distinct differences were found between large adenoma and protruding type of gallbladder carcinoma. There were distinct differences between adenomas and the protruding type gallbladder cancers, and there was a pathological basis for the differences. Benign tumors had a more homogeneous texture, had spaces between the tumor and the gallbladder wall and a relatively normal configuration of the gallbladder wall. Based on these findings, certain lesions could be definitively diagnosed as benign adenomas and could help in treatment strategy.
18F-FDG PET/CT metabolic parameters and HER2 expression in colorectal cancer
2021
Neoplasma (Bratislava)
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The relationship between 18F-FDG uptake and HER2 expression in colorectal cancer has not been investigated yet. This study aimed to investigate the predictive efficiency of preoperative 18F-FDG PET/CT for HER2 expression and prognosis in colorectal cancer. We retrospectively analyzed 131 colorectal cancer patients who underwent 18F-FDG PET/CT scans in our center before surgery. HER2 positivity was defined as a score of 2+ or 3+, and HER2 negativity was defined as a score of 0 or 1+ in
doi:10.4149/neo_2021_200803n807
pmid:33998235
fatcat:ynq3oenm55c4jayrxib7h7tugm
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... ochemistry of HER2 expression. The relationships between 18F-FDG PET/CT metabolic parameters and HER2 expression and the prognosis of colorectal patients were systematically studied. From 131 colorectal cancer patients, there were 27 (20.6%) HER2 positive patients. SUVmax of the primary tumor (mean±SD) in the HER2-positive and the HER2-negative group was 18.238±8.912 and 14.455±6.531, respectively. SUVmax in the HER2-positive group was higher than in the negative group (p=0.034). When the cutoff was based on 5 cm, tumor size demonstrated significant positive correlations with SUVmax (p=0.012) and HER2 expression (p=0.014). Multivariate analysis showed that both SUVmax and tumor size had a significant correlation with HER2 expression (p=0.049 vs. p=0.043, respectively). There was no statistical difference in PFS between the HER2-positive and the HER2-negative group (p=0.28). 18F-FDG metabolic parameters had a significant correlation with HER2 expression in colorectal cancer. SUVmax combined with primary tumor size were better for predicting the HER2 status of colorectal cancer.
Nitidine chloride inhibits SIN1 expression in osteosarcoma cells
2019
Molecular Therapy: Oncolytics
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Nitidine chloride (NC) has been demonstrated to exert a tumor-suppressive function in various types of human cancers. However, the detailed mechanism of NC-mediated anti-tumor effects remains elusive. It has been reported that SIN1, a component of mTORC2 (mammalian target of rapamycin complex C2), plays an oncogenic role in a variety of human cancers. Therefore, the inhibition of SIN1 could be useful for the treatment of human cancers. In this study, we explored whether NC triggered an
doi:10.1016/j.omto.2019.01.005
pmid:30847386
pmcid:PMC6389778
fatcat:5wx3os4epzhwrh3saoaetoi3de
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... er function via the inhibition of SIN1 in osteosarcoma (OS) cells. An MTT assay was performed to measure the effect of NC on the cell growth of osteosarcoma cells, and flow cytometry was used to detect the apoptotic rate of the cells after NC treatment. The expression of SIN1 was detected by western blotting. Wound-healing assay and Transwell chamber invasion assay were conducted to analyze the motility of osteosarcoma cells following NC exposure. We found that exposure to NC led to the inhibition of cell growth, migration, and invasion and the induction of apoptosis. Mechanistically, we found that NC inhibited the expression of SIN1 in osteosarcoma cells. Overexpression of SIN1 abrogated the inhibition of cell growth and motility induced by NC in osteosarcoma cells. Our results indicate that NC exhibits its tumor-suppressive activity via the inhibition of SIN1 in osteosarcoma cells, suggesting that NC could be a potential inhibitor of SIN1 in osteosarcoma.
Effects of Low Concentrations of Rotenone Upon Mitohormesis in SH-SY5Y Cells
2012
Dose-Response
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Yuyun and others 278 ROS, high expression of SIRT1 may repress PGC-1α transcription, leading to damage to the mass and function of mitochondria. ...
http://scholarworks.umass.edu/dose_response/vol11/iss2/12
Dose-Response: An International Journal, Vol. 11 [2014], Iss. 2, Art. 12 http://scholarworks.umass.edu/dose_response/vol11/iss2/12
Yuyun ...
doi:10.2203/dose-response.12-005.gao
pmid:23930106
pmcid:PMC3682202
fatcat:e633t2w6zngztl72qi44f25vcy
Asiatic Acid Prevents Oxidative Stress and Apoptosis by Inhibiting the Translocation of α-Synuclein Into Mitochondria
2018
Frontiers in Neuroscience
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., 2009a; Xu et al., 2012) . In this study, we found that AA protects against Parkinsonlike injury in drosophila, SH-SY5Y cells, and isolated mitochondria. ...
Copyright © 2018 Ding, Xiong, Sun, Chen, Gao and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). ...
doi:10.3389/fnins.2018.00431
pmid:30002614
pmcid:PMC6031891
fatcat:qabh3qm3lnhhhl5skhnhnfbvp4
Prediction of Malignant Acute Middle Cerebral Artery Infarction via Computed Tomography Radiomics
2020
Frontiers in Neuroscience
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Copyright © 2020 Wen, Li, He, Xu, Shu, Hu, Chen, Jiang and Gong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). ...
doi:10.3389/fnins.2020.00708
pmid:32733197
pmcid:PMC7358521
fatcat:fhwqy7c5frbcrimpxptudlgoc4
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