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The Application of Active Query K-Means in Text Classification [article]

Yukun Jiang
2021 arXiv   pre-print
Active learning is a state-of-art machine learning approach to deal with an abundance of unlabeled data. In the field of Natural Language Processing, typically it is costly and time-consuming to have all the data annotated. This inefficiency inspires out our application of active learning in text classification. Traditional unsupervised k-means clustering is first modified into a semi-supervised version in this research. Then, a novel attempt is applied to further extend the algorithm into
more » ... e learning scenario with Penalized Min-Max-selection, so as to make limited queries that yield more stable initial centroids. This method utilizes both the interactive query results from users and the underlying distance representation. After tested on a Chinese news dataset, it shows a consistent increase in accuracy while lowering the cost in training.
arXiv:2107.07682v1 fatcat:u42dbrl555ed7cbalvmvuwd7mu

A case of brucellosis-induced Guillain–Barre syndrome

Qian Li, Jianfeng Liu, Wenhui Jiang, Lisheng Jiang, Mengzhi Lu, Linping Xiao, Yukun Li, Yinghua Lan, Yongguo Li
2022 BMC Infectious Diseases  
Background Guillain–Barre syndrome (GBS) is a rare neurological complication of brucellosis, and neurobrucellosis is the most common, but they have many similarities in clinical manifestations. Many clinicians are accustomed to merely explaining the manifestations of nervous system involvement with neurobrucellosis, but they ignore the possibility of GBS, and this leads to misdiagnosis, untimely treatment, and serious consequences. Case presentation A 55-year-old male patient was admitted to
more » ... First Affiliated Hospital of Harbin Medical University for intermittent fever, fatigue, and waist pain more than three months. Brucellosis was diagnosed from the blood test. Although anti-brucella treatment was given at the time of diagnosis, the disease continued to progress. At the time of the cerebrospinal fluid systematic physical examination and the neuroelectrophysiological test, acute motor sensory axonal neuropathy was diagnosed. The patient was given immediately administered immunoglobulin therapy. After three months of systemic treatment, the patient's muscle strength of the distal limbs gradually recovered. The numbness of the limbs eased slowly, and urination function and respiratory function returned to normal. He could sit by himself. Conclusions The possibility of GBS should be closely monitored for when a brucellosis patient shows typical clinical manifestations of progressive muscle weakness, protein-cell separation of the cerebral spinal fluid, and typical demyelinating sensorimotor polyneuropathy.
doi:10.1186/s12879-021-07025-3 pmid:35057735 pmcid:PMC8781241 fatcat:3z7222tfsvcbxjr5a3nl2ehfde

Development of a Monitoring System for Smartphone Overuse

Jiang Li, Siguo Bi, Jiao-Er Ding, Yukun Lan, Hua Fu
2017 Iproceedings  
doi:10.2196/iproc.8305 fatcat:4a4kkzqegjfbxhjb7sfta4ekpa

Agreement or Disagreement in Noise-tolerant Mutual Learning? [article]

Jiarun Liu, Daguang Jiang, Yukun Yang, Ruirui Li
2022 arXiv   pre-print
Deep learning has made many remarkable achievements in many fields but suffers from noisy labels in datasets. The state-of-the-art learning with noisy label method Co-teaching and Co-teaching+ confronts the noisy label by mutual-information between dual-network. However, the dual network always tends to convergent which would weaken the dual-network mechanism to resist the noisy labels. In this paper, we proposed a noise-tolerant framework named MLC in an end-to-end manner. It adjusts the
more » ... etwork with divergent regularization to ensure the effectiveness of the mechanism. In addition, we correct the label distribution according to the agreement between dual-networks. The proposed method can utilize the noisy data to improve the accuracy, generalization, and robustness of the network. We test the proposed method on the simulate noisy dataset MNIST, CIFAR-10, and the real-world noisy dataset Clothing1M. The experimental result shows that our method outperforms the previous state-of-the-art method. Besides, our method is network-free thus it is applicable to many tasks. Our code can be found at
arXiv:2203.15317v2 fatcat:37ak6wzw55f2zntl24tg3gkvoe

Electric-triple-layer model based AC electroosmosis flow [article]

Jiang Hongyuan, Li Shanshan, Ren Yukun, Tao Ye
2012 arXiv   pre-print
The paper presents an novel electric triple layer(ETL) model as an improved model of electrical double layer(EDL) to predict electroosmosis flow rate on the electrode surface at low frequency. The predicted slip velocity based on classical EDL theory is much higher than experimental results, and ETL model can account for this deviation. Cross-over frequency at which the maximum electroosmosis flow velocity occurs based on ETL model is a little bit higher than that predicted in EDL theory, but
more » ... ill in keeping with classical prediction. Influences of triple layer thickness and electrode surface roughness on electroosmosis flow are analyzed via simulation and theoretical analysis agrees with experimental data very well, proving its validity.
arXiv:1008.4183v2 fatcat:3xqcvjenijfkfb5yha22hsisae

Experimental Study of Fast Sealing Airbag in Simulating Tunnel

Liming Jiang, Yinghua Zhang, Zhian Huang, Yukun Gao, Yanfeng Zhang
2012 Procedia Engineering  
Against problems in terms of stability, airtightness and so on of current fast sealing airbag, stability and airtightness of fast sealing airbag in simulating tunnel was studied through combining theoretical analysis and experiment. The ideal viton material is finally found after comparing and analyzing heat resistance, flame resistance, wear resistance, hardness and air permeability of different kinds of rubber. Sealing and wind blocking effects of airbags made from selected material are
more » ... in simulating tunnel. Rate of air leakage and changing rate of wind pressure of each kind of rubber are also determined and further verified, with result that both indexes of viton material are the least, respectively only 4.25% and 4.66%.
doi:10.1016/j.proeng.2012.08.239 fatcat:pohjmojpazg3hfoc2jjpxhc6bu

Recovery Algorithm of Power Metering Data Based on Collaborative Fitting

Yukun Xu, Xiangyong Kong, Zheng Zhu, Chao Jiang, Shuang Xiao
2022 Energies  
Electric energy metering plays a crucial role in ensuring fair and equitable transactions between grid companies and power users. With the implementation of the State Grid Corporation's energy Internet strategy, higher requirements have been put forward for power grid companies to reduce costs and increase efficiency and user service capabilities. Meanwhile, the accuracy and real-time requirements for electric energy measurements have also increased. Electricity information collection systems
more » ... e mainly used to collect the user-side energy metering data for the power users. Attributed to communication errors, communication delays, equipment failures and other reasons, some of the collected data is missed or confused, which seriously affects the refined management and service quality of power grid companies. How to deal with such data has been one of the important issues in the fields of machine learning and data mining. This paper proposes a collaborative fitting algorithm to solve the problem of missing collected data based on latent semantics. Firstly, a tree structure of user history data is established, and then the user groups adjacent to the user with missing data are obtained from this. Finally, the missing data are recovered using the alternating least-squares matrix factorization algorithm. Through numerical verification, this method has high reliability and accuracy in recoverying the missing data.
doi:10.3390/en15041570 fatcat:taxcpvmfijfs5i5ckxz7afxhmy

Electrically controlled rapid release of actives encapsulated in double-emulsion droplets

Yankai Jia, Yukun Ren, Likai Hou, Weiyu Liu, Tianyi Jiang, Xiaokang Deng, Ye Tao, Hongyuan Jiang
2018 Lab on a Chip  
We utilize electric fields to trigger the on-demand release of different cargos that are encapsulated in water-in-oil-in-water (W/O/W) double-emulsion droplets.
doi:10.1039/c7lc01387f pmid:29536065 fatcat:mmrtk4t4bbbavmzxcq6bo7bnka

Effect of the crossing-structure sequence on mixing performance within three-dimensional micromixers

Xiangsong Feng, Yukun Ren, Hongyuan Jiang
2014 Biomicrofluidics  
The geometry of crossing structure formed by two-layer microchannels determines the axial and transverse movements of contact interface between two liquid streams, which gives us a new method for promoting the micromixers. Hence, we designed four different three-dimensional micromixers by selecting two different crossing structures as basic units (one unit is a crossing structure called "X" and the other is a reversed crossing structure called "rX"). In order to find out how the
more » ... re sequence affects the mixing performance within three-dimensional micromixers, we organized these four mixers in different ways, i.e., the first combination is X-rX-X-rX-..., the second is X-rX-rX-X-..., the third is X-X-rX-X-..., and the last one is X-X-X-X.... Consequently, quite distinct mixing phenomena are engendered. Furthermore, experiments were also conducted using the first and the last models to verify the simulation results. We infer that the last mixer is more likely to trigger chaos and convection by rotating the contact surface than the first one that merely swings the surface even when the flow rates and viscosities of the two liquid streams are increased. V C 2014 AIP Publishing LLC.
doi:10.1063/1.4881275 pmid:24959307 pmcid:PMC4048443 fatcat:qfyotbwfl5e4vguqr7cb6sr4by

Ddelta: A deduplication-inspired fast delta compression approach

Wen Xia, Hong Jiang, Dan Feng, Lei Tian, Min Fu, Yukun Zhou
2014 Performance evaluation (Print)  
Delta compression, a promising data reduction approach capable of finding the small differences (i.e., delta) among very similar files and chunks, is widely used for optimizing replicate synchronization, backup/archival storage, cache compression, etc. However, delta compression is costly because of its time-consuming wordmatching operations for delta calculation. Our indepth examination suggests that there exists strong wordcontent locality for delta compression, which means that contiguous
more » ... licate words appear in approximately the same order in their similar versions. This observation motivates us to propose Edelta, a fast delta compression approach based on a word-enlarging process that exploits word-content locality. Specifically, Edelta will first tentatively find a matched (duplicate) word, and then greedily stretch the matched word boundary to find a likely much longer (enlarged) duplicate word. Hence, Edelta effectively reduces a potentially large number of the traditional time-consuming word-matching operations to a single word-enlarging operation, which significantly accelerates the delta compression process. Our evaluation based on two case studies shows that Edelta achieves an encoding speedup of 3X∼10X over the state-of-the-art Ddelta, Xdelta, and Zdelta approaches without noticeably sacrificing the compression ratio.
doi:10.1016/j.peva.2014.07.016 fatcat:4mdsayyxwnhbrg7twc334zcnuu

A general in vitro assay to study enzymatic activities of the ubiquitin system [article]

Yu Ye, Yukun Zuo, Kun Jiang, Boon Keat Chong, Daniel Finley, David Klenerman
2019 bioRxiv   pre-print
The ubiquitin (Ub) system regulates a wide range of cellular signaling pathways. Several hundred E1, E2 and E3 enzymes are together responsible for the conjugation of Ub to cellular proteins, thereby controlling biological activities. Due to the numerous enzymes and processes involved in ubiquitination, studies on the molecular mechanisms have been challenging. We here report a novel FRET-based assay to study the kinetics of ubiquitination. FRET is established between binding of
more » ... led Ub to eGFP-tagged ZnUBP, a domain that exclusively binds unconjugated Ub. We name this assay the Free Ub Sensor System (FUSS). Using Uba1, UbcH5 and CHIP as model enzymes, we demonstrate that ubiquitination rates can be measured by FUSS using the rate of change in the FRET efficiency over time. Treatment with USP21, a deubiquitinase, removes ubiquitination on CHIP and leads to increased FRET efficiency, confirming the reversibility of the assay. Incubation with tau, a substrate of CHIP, increases the overall ubiquitination activity. We further use this assay to measure the relationship between increasing E1, E2 or E3 concentrations and ubiquitination rates, revealing that Uba1 activity is the rate-limiting step. Our data together demonstrate the versatile applications of a novel ubiquitination assay that does not require labeling of E1, E2, E3 or substrates, and is thus potentially compatible with any E1-E2-E3 combinations.
doi:10.1101/660894 fatcat:36zhdxq6c5fybkvmjih6smo2la

Positive Solutions for Second-Order Nonlinear Ordinary Differential Systems with Two Parameters

Lan Sun, Yukun An, Min Jiang
2011 ISRN Applied Mathematics  
By using fixed-point theorem and under suitable conditions, we investigate the existence and multiplicity positive solutions to the following systems: , where are four positive constants and , , and . We derive two explicit intervals of and , such that the existence and multiplicity of positive solutions for the systems is guaranteed.
doi:10.5402/2011/612591 fatcat:t4dhuyuvprgf7c7tikiobzxxoy

The Manganese Salt (MnJ) Functions as A Potent Universal Adjuvant [article]

Rui Zhang, Chenguang Wang, Yukun Guan, Xiaoming Wei, Mengyin Sha, Miao Jing, Mengze Lv, Jing Xu, Yi Wan, Zhengfan Jiang
2019 bioRxiv   pre-print
Aluminum adjuvants have been used for a century in various vaccines due to its ability to potentiate humoral immunity and safety records since 1920s. Manganese is an essential micronutrient required for diverse biological activities in cells. We previously found that Mn2+ is a strong type I-interferon stimulator activating the cGAS-STING pathway. Herein we report that a colloidal manganese salt (MnJ) is a potent adjuvant to induce both humoral and cellular immune responses, particularly CTL
more » ... vation. When administrated intranasally, MnJ was also a strong mucosal adjuvant, inducing high levels of IgA antibodies. MnJ strongly promoted dendritic cell maturation and antigen-specific T cell activation. Interestingly, IL-1/-18 induction and release by Mn2+-activated ASC-mediated inflammasomes were not observed. MnJ showed great adjuvant effects to all tested antigens including inactivated viruses, recombinant proteins and peptides by either intramuscular or intranasal immunization. These findings may have implications in developing potent but safe Mn2+-containing vaccines.
doi:10.1101/783910 fatcat:dygmmwnrcng6jpft4lvr5vnivm

Thada Is Dispensable for Female Fertility in Mice

Shan Han, Yuqing Zhang, Yukun Zheng, Congcong Liu, Yonghui Jiang, Shigang Zhao, Han Zhao
2022 Frontiers in Endocrinology  
Genome-wide association studies (GWAS) have identified THADA as one of the susceptibility genes for polycystic ovary syndrome (PCOS). Single nucleotide polymorphisms (SNPs) in the THADA gene showed significant over-transmission in PCOS and strong correlations with testosterone level. However, there was insufficient evidence to verify the effect of THADA in vivo on female reproductive system. In this study, we investigated the impacts of Thada ablation on ovarian function and reproductive
more » ... s with knockout (KO) mice. The results showed that the Thada deletion was insufficient to affect ovarian folliculogenesis, steroidogenesis, and female fertility. Additionally, we stressed the mice with high-fat-high-sugar diet (HFHS). In this case, the KO mice still merely had a negligible impact on ovarian function. These findings indicated that Thada deficiency was dispensable for female fertility in mice, which enriched our knowledge about in vivo functions of PCOS susceptibility genes.
doi:10.3389/fendo.2022.787733 pmid:35480478 pmcid:PMC9037063 fatcat:sadgfhblsbekxl7nrh7yff7fyq

Particle rotational trapping on a floating electrode by rotating induced-charge electroosmosis

Yukun Ren, Weiyu Liu, Jiangwei Liu, Ye Tao, Yongbo Guo, Hongyuan Jiang
2016 Biomicrofluidics  
We describe a novel rotating trait of induced-charge electroosmotic slip above a planar metal surface, a phenomenon termed "Rotating induced-charge electro-osmosis" (ROT-ICEO), in the context of a new microfluidic technology for tunable particle rotation or rotational trap. ROT-ICEO has a dynamic flow stagnation line (FSL) that rotates synchronously with a background circularly polarized electric field. We reveal that the rotating FSL of ROT-ICEO gives rise to a net hydrodynamic torque that is
more » ... esponsible for rotating fluids or particles in the direction of the applied rotating electric field either synchronously or asynchronously, the magnitude of which is adjusted by a balance between rotation of FSL and amplitude of angular-direction flow component oscillating at twice the field frequency. Supported by experimental observation, our physical demonstration with ROT-ICEO proves invaluable for the design of flexible electrokinetic framework in modern microfluidic system. Published by AIP Publishing. [http://dx.
doi:10.1063/1.4962804 pmid:27703589 pmcid:PMC5035304 fatcat:ikccvor6fncfpncikfy5du3n3m
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