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Resting-state network topology and planning ability in healthy adults [article]

Chris Vriend, Margot Wagenmakers, Odile A van den Heuvel, Ysbrand D van der Werf
2019 bioRxiv   pre-print
P. van den Heuvel, Stam, Kahn, & Hulshoff Pol, 2009 ).  ...  There were 194 nodes common to all subjects with enough signal to (D) construct connectivity matrices (see text) using wavelet coherence.  ... 
doi:10.1101/696856 fatcat:lbmbjl2u6bdfnmaxloxkq4k4ji

Alpha Power Predicts Persistence of Bistable Perception

Giovanni Piantoni, Nico Romeijn, German Gomez-Herrero, Ysbrand D. Van Der Werf, Eus J. W. Van Someren
2017 Scientific Reports  
Sleep deprivation indeed affected the distribution of perceptual durations (Kolmogorov-Smirnov D = 0.089, p-value < 0.001) that became longer on average (0.251 log(s), s.e.m. 0.092, z-value = 2.728, p-value  ... 
doi:10.1038/s41598-017-05610-8 pmid:28701732 pmcid:PMC5507912 fatcat:na67dfzty5ekvi7ldhkwjlqvgi

The Sleeping Cerebellum

Cathrin B. Canto, Yoshiyuki Onuki, Bastiaan Bruinsma, Ysbrand D. van der Werf, Chris I. De Zeeuw
2017 Trends in Neurosciences  
Human scalp EEG data were obtained from Eus J.W. van Someren (personal communication). (B) Human cerebellar nuclei show sleep activity during both NREM and REM sleep.  ...  Neural representations of experiences can also become reactivated during sleep itself, stabilizing associated memories in long-term memory ( Figure 3C ). van Dongen and colleagues [100] initiated this  ... 
doi:10.1016/j.tins.2017.03.001 pmid:28431742 fatcat:wxnyfhxu55hwrpsvfulucbqpii

Hippocampal–Cerebellar Interaction During Spatio-Temporal Prediction

Yoshiyuki Onuki, Eus J.W. Van Someren, Chris I. De Zeeuw, Ysbrand D. Van der Werf
2013 Cerebral Cortex  
, B: second trajectory, C: third trajectory, D: right-most trajectory).  ...  (d) Mental rehearsal condition. The purpose of the condition is to imagine movements that require motor coordination and prediction timing. (e) Observation condition.  ... 
doi:10.1093/cercor/bht221 pmid:23968839 fatcat:jsefih5pfvf2lhqfdhdzrg55um

Neuropsychology of infarctions in the thalamus: a review

Ysbrand D Van der Werf, Menno P Witter, Harry B.M Uylings, Jelle Jolles
2000 Neuropsychologia  
The third patient showing executive dysfunctioning after a very limited infarction was described by Van Der Werf et al.  ...  der Werf et al. [79] Digit span forward and backward, Consonant Trigrams 15-word list 5 trials, RCF, Visual Association Learning Task Delayed recall Recognition Executive abilities WMS (logical  ... 
doi:10.1016/s0028-3932(99)00104-9 pmid:10689038 fatcat:wbxc6ec4lffanhkbywi7tk4ef4

Toward physiological indices of emotional state driving future ebook interactivity

Jan B.F. van Erp, Maarten A. Hogervorst, Ysbrand D. van der Werf
2016 PeerJ Computer Science  
We sincerely thank Arnon Grunberg and his publishers Elik Lettinga and Paulien Loerts from Nijgh & Van Ditmar for sharing their time and their creative minds.  ...  The paper also presents the data of the writer during the creation of emotional text (Van der Werf & Van Erp, 2014) .  ...  Tangermann, 2012; Van Erp et al., 2013; Van Erp et al., 2011) .  ... 
doi:10.7717/peerj-cs.60 fatcat:4fzx2tvxkjeadjrm3xlwsmeqne

Modulating spontaneous brain activity using repetitive transcranial magnetic stimulation

Ysbrand D van der Werf, Ernesto J Sanz-Arigita, Sanne Menning, Odile A van den Heuvel
2010 BMC Neuroscience  
technical support, and Eus van Someren for support in equipment.  ...  Acknowledgements The authors thank Richard van Dyck for financial support, Dick Veltman for conceptual advice, Maloe Hulst and Helene van Gorsel for contribution to data collection, Aart Nederveen for  ...  van der Werf et al. BMC Neuroscience 2010, 11:145 Page 4 of 6  ... 
doi:10.1186/1471-2202-11-145 pmid:21067612 pmcid:PMC2993720 fatcat:vj64s3tgazf6fbybqgitn6fkbu

Functional connectivity alterations in Parkinson's disease during the stop-signal task [article]

Chris Vriend, Douglas Leffa, James Trujillo, Niels Gerrits, Femke de Boer, Henk Berendse, Ysbrand D van der Werf, Odile A van den Heuvel
2018 bioRxiv   pre-print
A l l a r d , B r a i n d o p a m i n e r g i c m o d u l a t i o n a s s o c i a t e d w i t h e x e c u t i v e f u n c t i o n i n P a r k i n s o n ' s d i s e a s e , M o v D i s o r d 2 4 ( 1 3 )  ...  F a r i d , I . S i b o n , D . G u e h l , E . C u n y , P . B u r b a u d , M .  ... 
doi:10.1101/304584 fatcat:mx4hvi52gfc6vovcsfkzakv2om

Resting-state network topology and planning ability in healthy adults

Chris Vriend, Margot J. Wagenmakers, Odile A. van den Heuvel, Ysbrand D. van der Werf
2019 Brain Structure and Function  
There were 194 nodes common to all subjects with enough signal to (D) construct connectivity matrices (see text) using wavelet coherence.  ...  Details of the ToL task are provided in the study by (van den Heuvel et al. 2003) .  ... 
doi:10.1007/s00429-019-02004-6 pmid:31865409 fatcat:gzqkqpoix5dave4uawaxfy5emu

Processing speed is related to striatal dopamine transporter availability in Parkinson's disease

Chris Vriend, Tim D. van Balkom, Corné van Druningen, Martin Klein, Ysbrand D. van der Werf, Henk W. Berendse, Odile A. van den Heuvel
2020 NeuroImage: Clinical  
Parkinson's disease (PD) affects the integrity of the dopamine and serotonin system, and is characterized by a plethora of different symptoms, including cognitive impairments of which the pathophysiology is not yet fully elucidated. Investigate the role of the integrity of the dopaminergic and serotonergic system in cognitive functioning in early-stage PD using Single Photon Emission Computed Tomography (SPECT) combined with the radiotracer
more » ... nortropane (123I-FP-CIT). We studied the association between cognitive functions and dopamine transporter (DAT) availability in the caudate nucleus and putamen - as a proxy for striatal dopaminergic integrity - and serotonin transporter (SERT) availability as a proxy for serotonergic integrity in the thalamus and hippocampus using bootstrapped multiple regression. One-hundred-and-twenty-nine (129) PD patients underwent a 123I-FP-CIT SPECT scan and a neuropsychological assessment. We showed a positive association between DAT availability in the head of the caudate nucleus and the Stroop Color Word Task - card I (reading words; β = 0.32, P = 0.001) and a positive association between DAT availability in the anterior putamen and the Trail Making Test part A (connecting consecutively numbered circles; β = 0.25, P = 0.02). These associations remained after adjusting for motor symptom severity or volume of the region-of-interest and were most pronounced in medication-naïve PD patients. There were no associations between cognitive performance and SERT availability in the thalamus or hippocampus. We interpret these results as a role for striatal dopamine - and its PD-related decline - in aspects of processing speed.
doi:10.1016/j.nicl.2020.102257 pmid:32344372 pmcid:PMC7186552 fatcat:kzq7krhmwffuvdl3ubvz7ywn3m

Effect of Eight-Week Online Cognitive Training in Parkinson's Disease: A Randomized Controlled Trial [article]

Tim D. van Balkom, Henk W. Berendse, Ysbrand D. van der Werf, Jos W.R. Twisk, Carel F.W. Peeters, Rob H. Hagen, Tanja Berk, Odile A. van den Heuvel, Chris Vriend
2021 medRxiv   pre-print
M.W. van der Wijk, drs. M.A. Laansma, M.M.A. Schyns BSc., drs. M. Rombouts, drs. M.G.M.S. Schokker, drs. J.P.A. van Dulm MD, and drs. S. Kasprzak for their invaluable work on the data collection.  ...  E. van der Rheefor their input and suggestions in the execution and implementation of the trial. We acknowledge the support from the Brain Foundation Netherlands.  ... 
doi:10.1101/2021.03.04.21252499 fatcat:oc4na7eymbfwjfctdkpuwrehhe

The Importance of Sleep and Circadian Rhythms for Vaccination Success and Susceptibility to Viral Infections

Nina C. M. Schmitz, Ysbrand D. van der Werf, Heidi M. Lammers-van der Holst
2022 Clocks & Sleep  
In 2021, a study was initiated by Lammers-van der Holst and colleagues to investigate the association between sleep and circadian misalignment in relation to immune response to COVID-19 vaccination [53  ... 
doi:10.3390/clockssleep4010008 pmid:35225954 pmcid:PMC8884008 fatcat:oeqbvkdtkjafxoz4jvzrpouxgu

Disrupted directed connectivity along the cingulate cortex determines vigilance after sleep deprivation

Giovanni Piantoni, Bing Leung P. Cheung, Barry D. Van Veen, Nico Romeijn, Brady A. Riedner, Giulio Tononi, Ysbrand D. Van Der Werf, Eus J.W. Van Someren
2013 NeuroImage  
Someren, 2008; Van Der Werf et al., 2009 ) of slow waves.  ...  der Helm et al., 2011; Weissman et al., 2006) .  ... 
doi:10.1016/j.neuroimage.2013.04.103 pmid:23643925 pmcid:PMC3703622 fatcat:3h25kpkb4bftdjs3pswn64ybgm

The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices

Oliver Cameron Reddy, Ysbrand D. van der Werf
2020 Brain Sciences  
The glymphatic system is a "pseudo-lymphatic" perivascular network distributed throughout the brain, responsible for replenishing as well as cleansing the brain. Glymphatic clearance is the macroscopic process of convective fluid transport in which harmful interstitial metabolic waste products are removed from the brain intima. This paper addresses the glymphatic system, its dysfunction and the major consequences of impaired clearance in order to link neurodegeneration and glymphatic activity
more » ... th lifestyle choices. Glymphatic clearance can be manipulated by sleep deprivation, cisterna magna puncture, acetazolamide or genetic deletion of AQP4 channels, but how lifestyle choices affect this brain-wide clearance system remains to be resolved. This paper will synthesize existing literature on glymphatic clearance, sleep, Alzheimer's disease and lifestyle choices, in order to harness the power of this mass transport system, promote healthy brain ageing and possibly prevent neurodegenerative processes. This paper concludes that 1. glymphatic clearance plays a major role in Alzheimer's pathology; 2. the vast majority of waste clearance occurs during sleep; 3. dementias are associated with sleep disruption, alongside an age-related decline in AQP4 polarization; and 4. lifestyle choices such as sleep position, alcohol intake, exercise, omega-3 consumption, intermittent fasting and chronic stress all modulate glymphatic clearance. Lifestyle choices could therefore alter Alzheimer's disease risk through improved glymphatic clearance, and could be used as a preventative lifestyle intervention for both healthy brain ageing and Alzheimer's disease.
doi:10.3390/brainsci10110868 pmid:33212927 pmcid:PMC7698404 fatcat:jlig2rkdj5f5fdcfg64cgnk37e

Prefrontal hypoactivation and recovery in insomnia

Ellemarije Altena, Ysbrand D Van Der Werf, Ernesto J Sanz-Arigita, Thom A Voorn, Serge A R B Rombouts, Joost P A Kuijer, Eus J W Van Someren
2008 Sleep  
Preliminary results, in fact, demonstrate a lower baseline daytime perfusion of a corresponding left inferior frontal cortical region that shows attenuated activation in the current study (Van Der Werf  ...  One version contained the letters K, O, and M with the categories "animals," "tools," and "professions"; the other D, A, and T with "clothes," "vegetables/fruit," and "herbs."  ... 
pmid:18788652 pmcid:PMC2542967 fatcat:vsixfmh3o5aylneu4vbrut4sey
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