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Isolation and amino acid sequence of the 30S ribosomal protein S19 fromMycobacterium bovisBCG
1993
FEBS Letters
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The 30s ribosomal proteins from Mycobacteriurw bovis BCG were separated by reverse phase-high performance liquid chromatography (RP-HPLC). The isolated protems were analyzed by SDS-PAGE, blotted on PVDF-membranes and subjected to sequence analyses using a gas-phase sequencer to correlate them to those of the well studred Escher&a coli and Bucillus steurothernlophilus ribosomes. Moreover. the internal amino acid sequence of one ribosomal protem, MboS19, whtch IS homologous to E. colr rtbosomal
doi:10.1016/0014-5793(93)80287-5
pmid:8405418
fatcat:4mxcrulbnfawtoovin6bfdctfi
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... otein Sl9 (EcoS.19) and B. strurotlzermophrlus ribosomal protein S19 (BstSl9). was further analyzed by sequencing Its internal peptides and two segments from the N-and C-termini of the protein were selected to deduce the sequence of two ohgonucleotrde primers whtch were used m a polymerase chain reaction. Usmg the amplified DNA fragment thus obtained as a hybridization probe. the gene encoding protein S19 was identified and cloned. Sequence analysis of the DNA fragment, together with peptide sequence analysis could determine the complete ammo acid sequence of MboS19. This sequence proved to be 64% and 71% identical to those of the corresponding S19 proteins from the eubacteria E &I, and B. stearothern~ophrkts, respectively: 33% of the restdues of MboS19 were identical to those m the archaebacteral ribosomal protein HmaS19 Mycobacterww bows BCG; Ribosomal protein; Ammo actd sequence Published by Elsevier Science Publishers B V
Inhibitory Effects of Barbiturates on Nicotinic Acetylcholine Receptors in Rat Central Nervous System Neurons
2001
Anesthesiology
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Neuronal nicotinic acetylcholine receptors (nAChRs) are widely expressed in the central and autonomic nervous systems. The authors have previously shown that depressant and convulsant barbiturates both inhibit the gangliontype nAchRs in PC12 cells. However, the central and gangliontype receptors have different subunit composition and pharmacologic properties. In this study, the authors investigated the effects of thiopental, depressant [R(؊)] and convulsant [S(؉)] stereoisomers of 1-methyl-5
doi:10.1097/00000542-200104000-00025
pmid:11379692
fatcat:kufhiqv2a5h6lpu4nvnnunykzy
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... nyl-5-propyl barbituric acid (MPPB) on neuronal nAChRs in the rat central nervous system to explore significance of these effects in barbiturate anesthesia. Methods: Whole-cell currents were measured in acutely dissociated rat medial habenula (MHb) neurons by applying 10 or 100 M nicotine in the absence or presence of thiopental 3-100 M. Effects of R(؊)-and S(؉)-MPPB on the nicotine-induced current were also studied. Results: Thiopental suppressed the nicotine-elicited inward current and accelerated the current decay dose-dependently at the clinical relevant concentrations. R(؊)-and S(؉)-MPPB both inhibited the nicotine-induced current dose-dependently without augmenting the current decay. There was no significant difference in the magnitudes of inhibition by R(؊)-and S(؉)-MPPB. Conclusions: Although thiopental suppressed the current mediated through native nAchRs in rat MHb neurons at the clinically relevant concentrations, the depressant and convulsant stereoisomers of MPPB both inhibited the current in the same extent. These findings are consistent with the results previously obtained in the ganglion-type receptors of PC12 cells and suggest that inhibition of nAChRs in MHb neurons is not directly relevant to the hypnotic or anticonvulsive actions of barbiturates.
Inhibitory Effects of Isoflurane and Nonimmobilizing Halogenated Compounds on Neuronal Nicotinic Acetylcholine Receptors
2002
Anesthesiology
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Neuronal nicotinic acetylcholine receptors (nAchRs) are inhibited by low concentrations of volatile anesthetics. However, it is not clear whether this phenomenon contributes to the anesthetic effects of volatile anesthetics. Effects of a volatile anesthetic (isoflurane) and structurally related nonimmobilizers (F6: 1,2-dichlorohexafluorocyclobutane, F8: 2,3-dichlorooctafluorobutane) on the current mediated through neuronal nAchRs were studied. Method: This study investigated neuronal nAchRs in
doi:10.1097/00000542-200212000-00029
pmid:12459683
fatcat:jfi2tbx73jbj7e5aoq2a7xkg6q
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... C12 cells and acutely dissociated rat medial habenula (MHb) neurons. Whole cell currents elicited by 30 M nicotine were recorded in the absence and presence of the halogenated agents. The minimum alveolar concentrations (MACs) for F6 and F8 were predicted from Meyer-Overton correlation. Results: All halogenated compounds inhibited the nicotineinduced current in a concentration-dependent manner in PC12 cells. In MHb neurons, while isoflurane and F6 significantly inhibited the nicotine-induced peak current, F8 failed to inhibit it. The peak currents in the presence of isoflurane at 1.7 MAC, of F6 at 2.4 MAC, and of F8 at 2.2 MAC were 12, 31, and 97% of control, respectively. Conclusions: Isoflurane, F6, and F8 inhibited ganglion-type nAchRs in PC12 cells independent from their abilities to produce the anesthetic state. In MHb neurons, isoflurane and F6, which lack the immobilizing effect but has the amnesic effect, inhibited nAchRs. Native brain nicotinic receptors in MHb neurons were almost insensitive to F8, which lacks both the immobilizing and the amnesic effect. These results are consistent with the hypothesis that inhibition of nAchRs in MHb neurons is not important for the anesthetic effect but may contribute to the amnesic effect of these agents.
New Feature for Shadow Detection by Combination of Two Features Robust to Illumination Changes
2016
Procedia Computer Science
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Computer vision methods need to deal with shadows explicitly because shadows often have a negative effect on the results computed. A new shadow detection method is proposed. The proposed method is a shadow model based method. A new feature for detecting shadows is introduced. The feature is obtained by L*a*b* components, Peripheral Increment Sign Correlation and Normalized Vector Distance. These features are robust to illumination changes. Shadows can be treated as local illumination changes.
doi:10.1016/j.procs.2016.08.268
fatcat:o3q5itcdgvhojipj4cxa6a4bv4
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... ing these features results in removing shadow effects, in part. The histogram is generated by the three features and is treated as the feature for detecting shadows. The SVM is used for the classifier. The SVM is trained in advance by shadow data and the trained SVM is used for detecting shadows. The proposed method can extract shadows with the accuracy similar to the previous approach in shorter time. Results are demonstrated by experiments using the real videos.
Possible Involvement of Cancer Producing Thymic Stromal Lymphopoietin as an Initiator of Papuloerythroderma of Ofuji
2019
Annals of Dermatology
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ORCID Daisuke Ueo, https://orcid.org/0000-0001-7074-9058 Fumitaka Yoshizumi, https://orcid.org/0000-0001-7079-3833 Yoshinori Shirasaka, https://orcid.org/0000-0001-7377-1138 Masahiro Kitagawa, https:// ...
orcid.org/0000-0002-4518-8268 Koichi Ohshima, https://orcid.org/0000-0003-4996-5279 Shinya Higashi, https://orcid.org/0000-0001-5607-6563 Sakuhei Fujiwara, https://orcid.org/0000-0002-3281-0484 Yutaka ...
doi:10.5021/ad.2019.31.s.s56
pmid:33911698
pmcid:PMC7997068
fatcat:lyfmzmfchzgmfhsqxtchhtb2uq
回盲部病変の診断
Diagnosis of the Ileocecal Lesion
1981
Japanese Journal of National Medical Services
Diagnosis of the Ileocecal Lesion
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Sotaro SADAHIRO Takashi KONDO 慶 応 義 塾 大 学 医 学 部 School of Medicine, Keio University ***放 射 線 診 断 部 Yoshinori SUGINO (Diagnosis of the Ileocecal Lesion) -888- (医 療 第35巻 第10号) 表2 過去5年 間の注腸造影施行例 と疾患分類 術 ...
回盲部悪性腫瘍初発症状 国 立 大 蔵 病 院 Okura National Hospital *腸 疾 患 セ ン タ ー Hisashi SHINOHARA Toshiyoshi UTSUNOMIYA Koichi SUZUKI Toshifumi HIBI Tetsuharu KITAHORA **外 科 Hidetane ONISHI Toshihiko RO Akihiko TAKESHI Shigeki HIGASHI ...
doi:10.11261/iryo1946.35.888
fatcat:bvmcxtjonjf65b5legedaww3w4
アルミン酸八ホウ酸三カリウム,K3AlB8O15の結晶構造
The Crystal Structure of Tripotassium Aluminate Octaborate, K3AlB8O15
1982
Journal of the Ceramic Association Japan
The Crystal Structure of Tripotassium Aluminate Octaborate, K3AlB8O15
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A preliminary investigation of surface runoff and soil properties in a moso-bamboo (Phyllostachys pubescens) forest in western Japan
2010
Hydrological Research Letters
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To clarify plot-scale runoff characteristics in bamboo forests, soil properties and surface runoff were measured in a preliminary study of a forested hillslope of moso-bamboo (Phyllostachys pubescens). Infiltration capacities and saturated hydraulic conductivities at 10, 30 and 50 cm depths were similar to or greater in the moso-bamboo forest than in an adjacent broad-leaved forest. This suggests that surface runoff rarely occurs in the moso-bamboo forest. However, surface runoff was observed
doi:10.3178/hrl.4.80
fatcat:r5bnryql5ralzdxsffoy65lpei
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... seven of 14 storm events. The surface runoff responses to rainfalls were relatively rapid and the amount of surface runoff per storm event depended largely on rainfall. The proportion of the total amount of surface runoff to the total rainfall during the observation period ranged from 19 to 33%, depending on the observation system. This indicates that the greater portion of rainfall infiltrated into the soil. A high density of roots in the surface soil suggests that part of the rainfall was impeded and passed laterally through the surface soil as preferential flow around the root mats and/or the rhizomes, thereby contributing to surface runoff.
A Case of Amoebiasis with Continuation of Excreting Cysts
シスト排出が遅延した赤痢アメーバ症の1例
1997
Gastroenterological Endoscopy
シスト排出が遅延した赤痢アメーバ症の1例
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Observation of Canopy Interception Loss in an Abandoned Coniferous Plantation
管理放棄されたヒノキ人工林における樹冠遮断量の計測
2010
Journal of the Japanese Forest Society
管理放棄されたヒノキ人工林における樹冠遮断量の計測
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Observation of Canopy Interception Loss in an Abandoned Coniferous Plantation. J. Jpn. For. Soc. 92: 54 59. The number of abandoned coniferous plantations has increased greatly in recent year across Japan. However, though evapotranspiration greatly affects on available water resources, no study observing evapotranspiration in abandoned plantations has been reported. We observed canopy interception loss for four years in an abandoned coniferous plantation located in the Kasuya Research Forest of
doi:10.4005/jjfs.92.54
fatcat:mynq6276wbatlhqbvg6bzj2dqu
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... Kyushu University. Our results were compared with those obtained for other coniferous forests. The canopy interception loss ratio (interception loss/precipitation) we obtained was 24.9%. The relationship between stem density and interception ratio has previously reported. Indeed, the value we obtained was nearly that calculated based on that reported relationship; this information would be useful for examining whether the relationship derived from previous interception studies in coniferous plantations holds even for abandoned coniferous plantations.
Combined treatment of pancreatic cancer xenograft with 90Y-ITGA6B4-mediated radioimmunotherapy and PI3K/mTOR inhibitor
2017
World Journal of Gastroenterology
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Katsushi Kouda ( 0 0 0 0 -0 0 0 3 -3 6 0 8 -0 1 5 6 ) ; Yo s h i k a z u K u r o s a w a ( 0
doi:10.3748/wjg.v23.i42.7551
pmid:29204055
pmcid:PMC5698248
fatcat:4yxwkima6jaa7kg4pp3bi3iuoy
The Relation between the Pulmonary Tuberculosis and the Serum Protein Fraction
肺結核症と血清蛋白分画の関係について
1965
Japanese Journal of National Medical Services
肺結核症と血清蛋白分画の関係について
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The difference between the mechanism of 67Ga accumulation and 59Fe accumulation into cultured tumor cells
培養腫よう細胞における`67´Gaと`59´Feの集積機序の相違
1987
RADIOISOTOPES
培養腫よう細胞における`67´Gaと`59´Feの集積機序の相違
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A STUDY OF THE MYOFIBROUS ORGANIZATION OF THE M. RECTUS ABDOMINIS FROM HUMAN ADULTS
ヒト腹直筋の筋線維構成についての基礎的研究
1979
Journal of The Showa Medical Association
ヒト腹直筋の筋線維構成についての基礎的研究
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Alloy Design and Microstructural Evolution During Heat Treatment of Newly Developed Cast and Wrought Ni-Base Superalloy M647 for Turbine Disk Application
[chapter]
2020
The Minerals, Metals & Materials Series
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A new cast and wrought Ni-base superalloy, M647, has been developed for turbine disk application with high mechanical properties at elevated temperatures and reasonable hot deformability. Conventional Ni-base superalloys are known to be strengthened by primary, secondary, and tertiary c′, but optimal heat treatment is dependent upon specific chemical composition. For optimal mechanical properties, microstructural evolutions including austenitic c grain size and c′ morphology were identified for
doi:10.1007/978-3-030-51834-9_9
fatcat:tsoolh2ap5hhzfqallupk7x77m
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... M647. To evaluate these properties, a full-scale low-pressure turbine disk was manufactured. This was subjected to a sub-solvus solution heat treatment, such that primary c′ remained to prevent grain growth, enabling required mechanical properties, especially proof stress and low-cycle fatigue, to be achieved. As for secondary c′, precipitation behavior was controlled intentionally by changing cooling rate after solution treatment, and this also resulted in modifying the precipitation behavior of tertiary c′ during aging. In this study, microstructural evolution and tensile properties at 650°C were investigated to clarify the relationship between them and to identify the strengthening mechanisms. From the result of SEM observation, size distributions of secondary c′ had a clear relationship with cooling rate. Moreover, the mean diameter of secondary c′ was unchanged during aging and this suggested that only tertiary c′ was precipitated during aging. Finally, critical resolved shear stress was calculated using both weakly and strongly coupled dislocation models, and it was clear that M647 was strengthened by a high volume fraction of secondary c′ and a small volume fraction of fine tertiary c′ precipitates.
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