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Physiological responses to daily light exposure

Yefeng Yang, Yonghua Yu, Bo Yang, Hong Zhou, Jinming Pan
2016 Scientific Reports  
Long daylength artificial light exposure associates with disorders, and a potential physiological mechanism has been proposed. However, previous studies have examined no more than three artificial light treatments and limited metabolic parameters, which have been insufficient to demonstrate mechanical responses. Here, comprehensive physiological response curves were established and the physiological mechanism was strengthened. Chicks were illuminated for 12, 14, 16, 18, 20, or 22 h periods each
more » ... day. A quadratic relationship between abdominal adipose weight (AAW) and light period suggested that long-term or short-term light exposure could decrease the amount of AAW. Quantitative relationships between physiological parameters and daily light period were also established in this study. The relationships between triglycerides (TG), cholesterol (TC), glucose (GLU), phosphorus (P) levels and daily light period could be described by quadratic regression models. TG levels, AAW, and BW positively correlated with each other, suggesting long-term light exposure significantly increased AAW by increasing TG thus resulting in greater BW. A positive correlation between blood triiodothyronine (T3) levels and BW suggested that daily long-term light exposure increased BW by thyroid hormone secretion. Though the molecular pathway remains unknown, these results suggest a comprehensive physiological mechanism through which light exposure affects growth.
doi:10.1038/srep24808 pmid:27098210 pmcid:PMC4838836 fatcat:iac3tokeinfgdhzd5yqlsyuqi4

Artificial Polychromatic Light Affects Growth and Physiology in Chicks

Jinming Pan, Yefeng Yang, Bo Yang, Yonghua Yu, Wilfried A. Kues
2014 PLoS ONE  
Despite the overwhelming use of artificial light on captive animals, its effect on those animals has rarely been studied experimentally. Housing animals in controlled light conditions is useful for assessing the effects of light. The chicken is one of the best-studied animals in artificial light experiments, and here, we evaluate the effect of polychromatic light with various green and blue components on the growth and physiology in chicks. The results indicate that green-blue dual light has
more » ... side-effects on chick body mass, depending on the various green to blue ratios. Green-blue dual light with depleted and medium blue component decreased body mass, whereas enriched blue component promoted body mass in chicks compared with monochromatic green-or blue spectra-treated chicks. Moreover, progressive changes in the green to blue ratios of green-blue dual light could give rise to consistent progressive changes in body mass, as suggested by polychromatic light with higher blue component resulting in higher body mass. Correlation analysis confirmed that food intake was positively correlated with final body mass in chicks (R 2 50.7664, P50.0001), suggesting that increased food intake contributed to the increased body mass in chicks exposed to higher blue component. We also found that chicks exposed to higher blue component exhibited higher blood glucose levels. Furthermore, the glucose level was positively related to the final body mass (R 2 50.6406, P50.0001) and food intake (R 2 50.784, P50.0001). These results demonstrate that spectral composition plays a crucial role in affecting growth and physiology in chicks. Moreover, consistent changes in spectral components might cause the synchronous response of growth and physiology.
doi:10.1371/journal.pone.0113595 pmid:25469877 pmcid:PMC4254831 fatcat:i5dwtpup3nhsddjxrnqjhoquyq

Motion Detection in Satellite Video

Aigong Xu, Jiaqi Wu, Guo Zhang, Shenlin Pan, Taoyang Wang, Yonghua Jang, Xin Shen
2017 Journal of Remote Sensing & GIS  
In view of the problem of satellite video motion detection, a background subtraction method of combining global motion compensation and local dynamic updating is proposed. In the first instance, the improved ViBE model method is used to establish the background model in the middle frame. The background model has one more dynamic update factor. Secondly, the motion model of global scene between frames is estimated by using uniform blocked forward-back LK optical flow, and the global motion
more » ... sation is performed. Last but not least, comparison between compensated frame and model, and connected domain analysis are employed to detect and segment the motion objects. Even more, we can correct the update factor of model according to the "pseudo motion" judgment. And then, the model would be updated locally and adaptively. "Target-wise" evaluation recall rate method is proposed which statistic the object entirety but not pixels. We do four experiments using Skysat and JL1H video. The results show that the proposed method perform a favorable effect on "Target-wise" recall rate and the error detection rate is low. The "Target-wise" recall rate is better than 80%. The error detection rate is reduced by at least 10 times, and even more than 160 times, compared with the classical method. The method could be suitable for advanced application and motion analysis in satellite video
doi:10.4172/2469-4134.1000194 fatcat:pvzdiz76lbbu5jbzyhc2otkrf4

Bioinformatics Analysis of Prognostic Value of SPC24 in ccRCC and Pan-Cancer

Jipeng Zhang, Xinlei Chen, Jirong Wang, Pengfei Zhang, Xue Han, Youzhi Zhang, Yonghua Wang, Xiaokun Yang
2022 International Journal of General Medicine  
Based on data from public databases, we determined the expression level and clinical value of SPC24 in ccRCC and human pan-cancer.  ...  Our study revealed that SPC24 is a prognostic factor in ccRCC related to immunomodulation and has generalized value in pan-cancer.  ...  Pan-Cancer Analysis To explore the potential prognostic value of SPC24 in pan-cancer, we conducted the further research on SPC24 in the remaining 32 cancers, similar to the above analysis method.  ... 
doi:10.2147/ijgm.s348859 pmid:35125884 pmcid:PMC8807948 fatcat:puvyz66ykjh3hdwdeoloraxw2u

Human-Friendly Light-Emitting Diode Source Stimulates Broiler Growth

Jinming Pan, Yefeng Yang, Bo Yang, Wenhua Dai, Yonghua Yu, Frederick C. Leung
2015 PLoS ONE  
Previous study and our laboratory have reported that short-wavelength (blue and green) light and combination stimulate broiler growth. However, short-wavelength stimuli could have negative effects on poultry husbandry workers. The present study was conducted to evaluate the effects of human-friendly yellow LED light, which is acceptable to humans and close to green light, on broiler growth. We also aimed to investigate the potential quantitative relationship between the wavelengths of light
more » ... for artificial illumination and growth parameters in broilers. After hatching, 360 female chicks ("Meihuang" were evenly divided into six lighting treatment groups: white LED strips (400-700 nm, WL); red LED strips (620 nm, RL); yellow LED strips (580 nm, YL); green LED strips (514 nm, GL); blue LED strips (455 nm, BL); and fluorescent strips (400-700 nm, FL). From 30 to 72 days of age, broilers reared under YL and GL were heavier than broilers treated with FL (P < 0.05). Broilers reared under YL obtained the similar growth parameters with the broilers reared under GL and BL (P > 0.05). Moreover, YL significantly improved feeding efficiency when compared with GL and BL at 45 and 60 days of age (P < 0.05). In addition, we found an age-dependent effect of light spectra on broiler growth and a quantitative relationship between LED light spectra (455 to 620 nm) and the live body weights of broilers. The wavelength of light (455 to 620 nm) was found to be negatively related (R 2 = 0.876) to live body weight at an early stage of development, whereas the wavelength of light (455 to 620 nm) was found to be positively correlated with live body weight (R 2 = 0.925) in older chickens. Our results demonstrated that human-friendly yellow LED light (YL), which is friendly to the human, can be applied to the broilers production.
doi:10.1371/journal.pone.0135330 pmid:26270988 pmcid:PMC4536231 fatcat:lrw32n6cl5fezlam4kwaffwtwq

Development of genomic resources for the genus Celtis (Cannabaceae) based on genome skimming data

Luxian Liu, Yonghua Zhang, Pan Li
2020 Plant Diversity  
Celtis is a Cannabaceae genus of 60-70 species of trees, or rarely shrubs, commonly known as hackberries. This woody genus consists of very valuable forest plants that provide important wildlife habitat for birds and mammals. Although previous studies have identified its phylogenetic position, interspecific relationships within Celtis remain unclear. In this study, we generated genome skimming data from five Celtis species to analyze phylogenetic relationships within the genus and develop
more » ... resources. The plastomes of Celtis ranged in length from 158,989 bp to 159,082 bp, with a typical angiosperm quadripartite structure, and encoded a total of 132 genes with 20 duplicated in the IRs. Comparative analyses showed that plastome content and structure were relatively conserved. Whole plastomes showed no signs of gene loss, translocations, inversions, or genome rearrangement. Six plastid hotspot regions (trnH-psbA, psbA-trnK, trnG-trnR, psbC-trnS, cemA-petA and rps8-rpl14), 4097 polymorphic nuclear SSRs, as well as 62 low or single-copy gene fragments were identified within Celtis. Moreover, the phylogenetic relationships based on the complete plastome sequences strongly endorse the placement of C. biondii as sister to the ((((C. koraiensis, C. sinensis), C. tetrandra), C. julianae), C. cerasifera) clade. These findings and the genetic resources developed here will be conducive to further studies on the genus Celtis involving phylogeny, population genetics, and conservation biology.
doi:10.1016/j.pld.2020.09.005 pmid:33778224 pmcid:PMC7987720 fatcat:ikjmv6k4ufaz3bm57hki6hquai

Visual deprivation modifies oscillatory activity in visual and auditory centers

Ping Pan, You Zhou, Fanghao Fang, Guannan Zhang, Yonghua Ji
2018 Animal Cells and Systems  
Loss of vision may enhance the capabilities of auditory perception, but the mechanisms mediating these changes remain elusive. Here, visual deprivation in rats resulted in altered oscillatory activities, which appeared to be the result of a common mechanism underlying neuronal assembly formation in visual and auditory centers. The power of high-frequency β and γ oscillations in V1 (the primary visual cortex) and β oscillations in the LGN (lateral geniculate nucleus) was increased after one week
more » ... of visual deprivation. Meanwhile, the power of β oscillations in A1 (the primary auditory cortex) and the power of β and γ oscillations in the MGB (medial geniculate body) were also enhanced in the absence of visual input. Furthermore, nerve tracing revealed a bidirectional nerve fiber connection between V1 and A1 cortices, which might be involved in transmitting auditory information to the visual cortex, contributing to enhanced auditory perception after visual deprivation. These results may facilitate the better understanding of multisensory cross-modal plasticity.
doi:10.1080/19768354.2018.1474801 pmid:30460092 pmcid:PMC6138323 fatcat:7ewvdc6cgbdd5kdem37ksao4cu

Effect of Microstructure on Layered Double Hydroxides Film Growth on Mg-2Zn-xMn Alloy

Yonghua Chen, Wenhui Yao, Liang Wu, Jing Chen, Fusheng Pan
2021 Coatings  
The poor corrosion resistance of magnesium (Mg) alloys significantly restricts their wide applications. The preparation of a layered double hydroxides (LDHs) film can provide effective corrosion protection for Mg alloys. Nevertheless, research on the effect of the Mg alloy microstructure on LDHs film growth is paid less attention, which was studied in detail in this work. Herein, a Mg-2Zn-xMn alloy with different Mn contents was produced, and an LDHs film was then synthesized on their surfaces.
more » ... The addition of Mn causes a different microstructure in the Mg-2Zn-xMn alloy, which is gradually refined with increasing Mn content, further affecting the surface morphology, surface chemistry, and corrosion protection of the LDHs film. When the Mn content is 1 wt.% (x = 1), the LDHs film presents the best corrosion protection, with the lowest corrosion current density. No obvious corrosion product could be observed by the naked eyes on the surface. By contrast, severe corrosion occurs on the Mg-2Zn-0Mn alloy (x = 0). Finally, the LDHs film growth mechanism was proposed.
doi:10.3390/coatings11010059 fatcat:qmburypbrnfuvm2r7jzruytsty

Asynchronous meiosis in Cucumis hystrix –cucumber synthetic tetraploids resulting in low male fertility

Yonghua Han, Junsong Pan, Paradee Thammapichai, Zongyun Li, Yiqun Weng
2016 Crop Journal  
American pickling cucumber inbred line, Gy14, from which amphidiploid plants were successfully obtained (Fig. 1 ) by chemical induction of chromosome doubling in TH1 (female) × Gy14 (pollen donor) mating (Pan  ... 
doi:10.1016/j.cj.2016.05.003 fatcat:je3c57rpp5c2bjdo3bmsnda6eu

Crustal and uppermost mantle structure of SE Tibetan plateau from Rayleigh-wave group-velocity measurements

Yonghua Li, Jiatie Pan, Qingju Wu, Zhifeng Ding
2014 Earthquake Science  
A shear-wave velocity model of the crust and uppermost mantle beneath the SE Tibetan plateau was derived by inverting Rayleigh-wave group-velocity measurements of periods between 10 and 70 s. Rayleigh-wave group-velocity dispersions along more than 3,000 interstation paths were measured based on analysis of teleseismic waveform data recorded by temporary seismic stations. These observations were then utilized to construct 2D group-velocity maps in the period range of 10-70 s. The new
more » ... ity maps have an enhanced resolution compared with previous global and regional group-velocity models in this region because of the denser and more uniform data coverage. The lateral resolution across the region is about 0.5°for the periods used in this study. Local dispersion curves were then inverted for a 3D shear-wave velocity model of the region by applying a linear inversion scheme. Our 3D shear-wave model confirms the presence of low-velocity zones (LVZs) in the crust beneath the northern part of this region. Our imaging shows that the upper-middle crustal LVZ beneath the Tengchong region is isolated from these LVZs beneath the eastern and northern part of this region. The upper-middle crustal LVZ may be regarded as evidence of a magma chamber in the crust beneath the Tengchong Volcanoes. Our model also reveals a slow lithospheric structure beneath Tengchong and a fast shield-like mantle beneath the stable Yangtze block.
doi:10.1007/s11589-014-0090-z fatcat:kfz7dkpfxjg3rgg2kzakicoyv4

A new method to manipulate broiler chicken growth and metabolism: Response to mixed LED light system

Yefeng Yang, Yonghua Yu, Jinming Pan, Yibin Ying, Hong Zhou
2016 Scientific Reports  
Present study introduced a new method to manipulate broiler chicken growth and metabolism by mixing the growth-advantage LED. We found that the green/blue LED mixed light system (G-B and G × B) have the similar stimulatory effect on chick body weight with single green light and single blue light (G and B), compared with normal artificial light (P = 0.028). Moreover, the percentage of carcass was significantly greater in the mixed light (G × B) when compared with the single light (P = 0.003).
more » ... chronized with body weight, the mixed light (G-B and G × B) had a significant improved influence on the feed conversion of birds compared with normal light (P = 0.002). A significant improvement in feed conversion were found in mixed light (G × B) compared with single LED light (P = 0.037). G group resulted in a greater high-density lipoprotein cholesterol level than B group (P = 0.002), whereas B group resulted in a greater low-density lipoprotein cholesterol level than G group (P = 0.017). The mixed light significantly increased the birds' glucose level in comparison with the single light (P = 0.003). This study might establish an effective strategy for maximizing growth of chickens by mixed LED technology. With impacts of climate change, issues such as more frequent and serious droughts, floods, and storms as well as diseases are becoming more serious threats to agriculture. These threats along with shortage of food supply make people turn to indoor and urban farming (such as vertical farming) for help. With proper lighting, indoor agriculture eliminates weather-related crop failures to provide year-round agriculture production, which assist in supplying food in cities with surging populations and in areas of severe environmental conditions. Therefore, light supplementation serve as a powerful tool in agriculture production 1-3 . Previous studies indicate that light play a vital role in affecting function and behavior of chickens 4-7 . Further it has been reported that light manipulation has been an effective measure to improve poultry production 8-10 . On the one hand, poultry have highly specialized visual systems and the majority of their behavior is mediated by vision 11 . The poultry retina possesses one of the most sophisticated cone photoreceptor systems among vertebrates. Poultry have five types of cones, including four single cones that support tetrachromatic color vision and one double cone, which is thought to mediate achromatic motion perception. Tetrachromatic color vision is mediated by four types of single cones that are maximally responsive to violet, blue, green and red light 12 . Second, light is in control of many physiological and behavioral processes of poultry. Circadian regulation of energy homeostasis is controlled by an endogenous biological clock, located in the suprachiasmatic nuclei (SCN) of the hypothalamus, that is synchronized by photic information that travels directly from light-sensitive ganglion cells in the retina to the SCN, thereby entraining individuals' physiology and behavior to the ambient light 13 . Importantly, light is a powerful exogenous factor entraining signal for circadian clock, although other factors such as food consumption influence clock signaling 13 . Therefore, light plays a vital role in affecting the growth and the development of poultry. The only light source for chickens in an environmentally controlled chicken house is artificial light. Thus, the light wavelength (quality), the light intensity (quantity), and the light period (regime) have become major
doi:10.1038/srep25972 pmid:27170597 pmcid:PMC4864324 fatcat:o3mklzgtl5fytnm6xepjkvcjt4

Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis

Yonghua Pan, Zhenyi Liu, Jie Shen, Raphael Kopan
2005 Developmental Biology  
2003; Sun et al., 2000 Sun et al., , 2002 and the skin (Pan et al., 2004) .  ...  Experimental procedure Mice The generation of compound mutants PSDCKO, N1CKO and N1N2CKO with Msx2-Cre and Prx1-Cre was done essentially as described (Pan et al., 2004) .  ... 
doi:10.1016/j.ydbio.2005.08.037 pmid:16169548 fatcat:tm4q344u7rbrrlovi5k3bqryk4

Smoking and impaired bone healing: will activation of cholinergic anti-inflammatory pathway be the bridge?

Yonghua Chen, Qingshan Guo, Xiaohua Pan, Ling Qin, Peng Zhang
2011 International Orthopaedics  
Purpose This review was written to analyse the potential role of the cholinergic anti-inflammatory pathway in smoking-induced impairment of the bone healing process. Methods Literature in PubMed was reviewed by entering the following keywords "smoking AND bone healing", "cholinergic anti-inflammatory pathway AND tumour necrosis factor", "tumour necrosis factor AND bone healing". All the related papers were recruited and carefully selected according to the content of this paper.
doi:10.1007/s00264-011-1243-5 pmid:21409368 pmcid:PMC3167453 fatcat:r7pm6h7fnrbnddtgcwc6gneocu

Insights on Structural Characteristics and Ligand Binding Mechanisms of CDK2

Yan Li, Jingxiao Zhang, Weimin Gao, Lilei Zhang, Yanqiu Pan, Shuwei Zhang, Yonghua Wang
2015 International Journal of Molecular Sciences  
Cyclin-dependent kinase 2 (CDK2) is a crucial regulator of the eukaryotic cell cycle. However it is well established that monomeric CDK2 lacks regulatory activity, which needs to be aroused by its positive regulators, cyclins E and A, or be phosphorylated on the catalytic segment. Interestingly, these activation steps bring some dynamic changes on the 3D-structure of the kinase, especially the activation segment. Until now, in the monomeric CDK2 structure, three binding sites have been
more » ... including the adenosine triphosphate (ATP) binding site (Site I) and two non-competitive binding sites (Site II and III). In addition, when the kinase is subjected to the cyclin binding process, the resulting structural changes give rise to a variation of the ATP binding site, thus generating an allosteric binding site (Site IV). All the four sites are demonstrated as being targeted by corresponding inhibitors, as is illustrated by the allosteric binding one which is targeted by inhibitor ANS (fluorophore 8-anilino-1-naphthalene sulfonate). In the present work, the OPEN ACCESS Int. J. Mol. Sci. 2015, 16 9315 binding mechanisms and their fluctuations during the activation process attract our attention. Therefore, we carry out corresponding studies on the structural characterization of CDK2, which are expected to facilitate the understanding of the molecular mechanisms of kinase proteins. Besides, the binding mechanisms of CDK2 with its relevant inhibitors, as well as the changes of binding mechanisms following conformational variations of CDK2, are summarized and compared. The summary of the conformational characteristics and ligand binding mechanisms of CDK2 in the present work will improve our understanding of the molecular mechanisms regulating the bioactivities of CDK2.
doi:10.3390/ijms16059314 pmid:25918937 pmcid:PMC4463590 fatcat:v7uijrrqenc5pnr4nsiwl4flra

The lithospheric thinning of the North China Craton inferred from Rayleigh waves inversion

Yonghua Li, Qingju Wu, Ruiqing Zhang, Jiatie Pan, Fengxue Zhang, Rongsheng Zeng
2009 Geophysical Journal International  
S U M M A R Y Joint inversion of interstation phase and group velocity dispersion data of Rayleigh waves provides the regional shear-wave velocity structure of the lithosphere across the central and eastern block of the North China Craton (NCC). Both the velocity dispersion curves and V s structure show strong lateral variation across the NCC, which correlates well with the regional tectonic evolution. At the lower crustal level, the characteristics of V s structure reveal differences in
more » ... tion of the two blocks. In the upper mantle, the lithospheric removal in the eastern NCC is more severe than in the central NCC. The V s differences between the central NCC and the eastern NCC imply that multistage reactivation of the NCC occurred in the Mesozoic and Cenozoic time.
doi:10.1111/j.1365-246x.2009.04169.x fatcat:emf3fvb7arhbbkrwmpzenqy57u
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