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Insomnia, Inattention and Fatigue Symptoms of Women with Premenstrual Dysphoric Disorder

Pai-Cheng Lin, Chih-Hung Ko, Yen-Ju Lin, Ju-Yu Yen
2021 International Journal of Environmental Research and Public Health  
Aim: Premenstrual dysphoric disorder (PMDD) has predictable, cyclic, psychological, and somatic symptoms, such as sleep problems. They result in functional impairment, are aggravated in the late luteal phase of the menstrual cycle, and are resolved by menstruation. The present study evaluated the insomnia, inattention, and fatigue symptoms of PMDD and their fluctuations during the menstrual cycle. Methods: A total of 100 women were diagnosed as having PMDD based on psychiatric interviews and a
more » ... rospective investigation of three menstrual cycles. A total of 96 individuals without PMDD were recruited as controls. Their symptoms, namely insomnia, inattention, and fatigue as well as functional impairment were assessed by using the premenstrual symptoms screening tool, the Pittsburgh insomnia rating scale, the attention and performance self-assessment scale, and the fatigue-assessment scale during both premenstrual and follicular phases. Results: In both the premenstrual and follicular phases, women with PMDD experienced more severe insomnia, inattentiveness, and fatigue than did women in the control group. A paired t-test demonstrated that women with PMDD had more severe severity insomnia, inattentiveness, and fatigue in the luteal phase than in the follicular phase. A repeated-measures analysis of variance demonstrated that the interaction period of PMDD and a menstrual cycle was significantly associated with insomnia, inattentiveness, and fatigue. A further correlation analysis demonstrated that all three symptoms were positively associated with self-reported functional impairment due to PMDD. Conclusions: Our results demonstrated that women with PMDD experienced an exacerbation of insomnia, memory problems, difficulty maintaining focus, and fatigue in the premenstrual phase. These symptoms are correlated with PMDD symptoms severity and functional impairment, and as such, they should be evaluated, and interventions should be employed in the late luteal phase of women with PMDD.
doi:10.3390/ijerph18126192 fatcat:lqslwo5srjaxxbhbjsztpoayde

Therapeutic Effect of Repurposed Temsirolimus in Lung Adenocarcinoma Model

Hsuen-Wen Chang, Min-Ju Wu, Zih-Miao Lin, Chueh-Yi Wang, Shu-Yun Cheng, Yen-Kuang Lin, Yen-Hung Chow, Hui-Ju Ch'ang, Vincent H. S. Chang
2018 Frontiers in Pharmacology  
., 2007; Lin et al., 2007; Gallotta et al., 2010; Wynne and Djakiew, 2010; Endo et al., 2014; Li et al., 2016) . We focused on the topscoring candidates and clinically approved antineoplastic drugs.  ... 
doi:10.3389/fphar.2018.00778 pmid:30087612 pmcid:PMC6066584 fatcat:vf2srikjnfbd7mzldvbytkbaje

Dusty plasma liquids [article]

Chan Chia-Ling, Lai Ying-Ju, Woon Wei-Yen, Chu Hong-Yu, I. Lin
2004 arXiv   pre-print
The dusty plasma liquid formed by micro-meter sized particles negatively charged and suspended in a low pressure discharge background is a good candidate to study the generic spatio-temporal dynamical behaviors at the kinetic level through direct optical video-microscopy, because of the sub-mm interparticle spacing and the slow time scale. In this paper, starting from the basic picture of the avalanche type stick-slip cooperative hopping process under the interplay of mutual coupling and the
more » ... chastic thermal agitation, we briefly review our recent study on particle micro-motion and the associated structural rearrangement. The effect of mesoscopic confinement and external slow shear drive are also discussed.
arXiv:physics/0410042v1 fatcat:vbcmhetqqjagjgeqjsibvauzem


Blossom Yen-Ju Lin, Wen-Jye Leu, Gerald-Mark Breen, Wen-Hung Lin
2008 Health Care Management Review  
, Yeh, & Lin, 2007) .  ...  environment in the health care industry from a more psychologyoriented perspective (Desselle & Holmes, 2007; Mott, Doucette, Gaither, Pedersen, & Schommer, 2004) or job-characteristics perspectives (Lin  ... 
doi:10.1097/01.hmr.0000304504.27803.64 pmid:18360166 fatcat:cfglhshggrgiveemkpofb5lvsu

Addiction and the Utilization of Medical Care

Yen-Ju Lin, Chun-Chih Chen, Tsai-Ching Liu, Ying-Tzu Lin
2012 Economics Research International  
We investigate the effect of different scales of addictive factors on the utilization of medical services in this paper using a two-part model. Data are from the 2005 National Health Interview Survey and the claims data in the National Health Insurance Research Database in Taiwan. The results show that personal addictive behavior is significantly associated with both outpatient and inpatient utilization. Moreover, our result implies that those who smoked at least 20 cigarettes per day might not
more » ... visit a doctor until the illness was severe. It suggests that the government can accomplish these goals by promotion and education in order to increase public awareness of personal health.
doi:10.1155/2012/801204 fatcat:dn23v73bufdi3hmeypqfxtpcgi

Room Temperature Terahertz Spectrometer with Quantum-Level Sensitivity [article]

Ning Wang, Semih Cakmakyapan, Yen-Ju Lin, Hamid Javadi, Mona Jarrahi
2018 arXiv   pre-print
Yen-Ju Lin designed and fabricated the IF circuits. Hamid Javadi assisted with project supervision and heterodyne spectrometer characterization.  ... 
arXiv:1806.05256v1 fatcat:3rxaxeoesbhxpblbw6wqxsy2bi

Levered Returns: Factors or Characteristics?

Kuan-Cheng Ko, Shinn-Juh Lin, Ju-Fang Yen
2011 Social Science Research Network  
This paper provides a risk-based explanation for the leverage anomalies. Following Daniel and Titman's (1997) methodology, we show that the characteristic-based explanations for the book-leverage and the market-leverage anomalies are both rejected by Ferguson and Shockley's (2003) leverage-based three-factor model, which receives stronger support for the period before 1980. With independent samples from six other non-U.S. G7 countries, we obtain robust results which support the superiority of
more » ... rguson and Shockley's (2003) three-factor model in explaining the leverage anomalies. Further evidence shows that leverage premia are reduced, or even eliminated after returns are adjusted by Ferguson and Shockley's factors. JEL Classification: G10; G12; G32.
doi:10.2139/ssrn.1911772 fatcat:yyc76lts7bfjfouhv5sxowosde

Vertical Outsourcing and Location Choice

Yen-Ju Lin, Kuang-I Tu
2013 Procedia Economics and Finance  
Most regional literature focuses on competition among final goods, but little of it integrates an intermediate goods market into the models used. This paper develops a variant of Hotelling's model involving an intermediate goods market in order to explore the location choices of firms. We consider interactions among three firms: a wholesale supplier of an essential input and two retail producers. One of these retailers is a vertically integrated firm. The other is an independent downstream
more » ... Within this framework, this paper will discuss the role of strategic vertical outsourcing in determining optimal locations for firms, and it will also explore the input pricing of wholesale suppliers. In general, the two firms were located more closely when the vertically integrated firm had a cost advantage without taking strategic outsourcing into consideration. However, the price of the input may increase when we take strategic vertical outsourcing into account in the model, and this may cause the two firms to move farther away, giving rise to the Principle of Minimum Differentiation.
doi:10.1016/s2212-5671(13)00058-0 fatcat:jatknzv2tjh2rc567vhc7dt2bq

Interaction of Alcohol Consumption and ABCG2 rs2231142 Variant Contributes to Hyperuricemia in a Taiwanese Population

I-Chieh Chen, Yen-Ju Chen, Yi-Ming Chen, Hsueh-Ju Lin, Ying-Cheng Lin, Jui-Chun Chagn, Pei-Chun Chen, Ching-Heng Lin
2021 Journal of Personalized Medicine  
ABCG2 rs2231142 is an important genetic factor that contributes to the development of gout and hyperuricemia (HUA). Epidemiologic studies have demonstrated that lifestyle risk factors of HUA (e.g., alcohol consumption) and genetic predisposition (e.g., ABCG2 gene) together, contribute to enhanced serum uric acid levels. However, the interaction between ABCG2 rs2231142, alcohol consumption, and HUA in the Taiwanese population is still unclear. Therefore, this study investigated whether the risk
more » ... f HUA is associated with ABCG2 rs2231142 variants and how this is affected by alcohol consumption. Method: study subjects were selected from the participants of the Taiwan Biobank database. Overall, 114,540 participants aged 30 to 70 years were enrolled in this study. The interaction between ABCG2 rs2231142, alcohol consumption, and serum uric acid (sUA) levels was analyzed by multiple logistic regression models. Results: the prevalence of HUA was 32.7% and 4.4 % in the male and female populations, respectively. In the whole study population, the minor T allele of ABCG2 rs2231142 was significantly associated with HUA risk, and the occurrence of HUA was high in TT genotype and TG genotype. The risk of HUA was significantly increased by the combined association of ABCG2 rs2231142 and alcohol consumption for TG/TT genotype compared to the GG genotype (wild-type genotype), especially among women. Conclusion: the ABCG2 rs2231142 is a crucial genetic locus for sUA levels in the Taiwanese population and our findings revealed that alcohol consumption combined with the ABCG2 rs2231142 risk allele contributes to increased HUA risk.
doi:10.3390/jpm11111158 pmid:34834509 pmcid:PMC8618280 fatcat:vyy5p7lhpjh35f25n3xw2e5pym

Association of ABCG2 rs2231142 Allele and BMI With Hyperuricemia in an East Asian Population

Yen-Ju Chen, I-Chieh Chen, Hsueh-Ju Lin, Ying-Cheng Lin, Jui-Chun Chang, Yi-Ming Chen, Tzu-Hung Hsiao, Pei-Chun Chen, Ching-Heng Lin
2021 Frontiers in Genetics  
., 2016; Lin et al., 2019) .  ... 
doi:10.3389/fgene.2021.709887 pmid:34531894 pmcid:PMC8438144 fatcat:t4rn3scmrre35d5g23io2adewy

Facility evaluation of resigned hospital physicians:managerial implications for hospital physician manpower

Kao-Chi Cheng, Tsung-Lin Lee, Yen-Ju Lin, Chiu-Shong Liu, Cheng-Chieh Lin, Shih-Wei Lai
2016 BioMedicine  
S.-W. Lai). turnover rates [6] . A working culture that fosters high employee motivation is necessary for an organization to compete in the highly dynamic and competitive environments of today's society. Managers need to implement effective human resource strategies and policies to establish and maintain such a working culture in any organization. High employee turnover rates can have a significantly negative impact on operation results for managers and organizations [7] . When an employee is
more » ... anning to resign, productivity and quality of work is likely to decline. Meanwhile, improving employee retention can result in positive outcomes for an organization, including workforce stability, employee selection cost savings, and managers having to spend less time interviewing prospective employees and integrating replacements into the ABSTRACT Introduction: Turnover of physicians might be responsible for reducing patients' trust and affecting hospital performance. This study aimed to understand physicians' psychological status regarding their hospital work environment and the resources of independent practitioners. Method: This was a cross-sectional study with 774 physicians who had resigned from hospitals and were now practicing privately in clinics in Taichung City as its study population. A mail survey with a multidimensional questionnaire was sent to each subject. Results: This study revealed that older physicians were less satisfied regarding the work environment in their respective former hospitals. Male physicians were found to be more satisfied with the tangible resources of their hospitals. Internal medicine physicians were found to be less satisfied overall with the intangible resources. Gynecologists and pediatricians were found to be more satisfied with their hospital environments. The physicians who worked long hours per week reported that they were less satisfied with their job content. The physicians who had opportunities to learn advanced skills and enhance their knowledge were more satisfied with their hospital environment, tangible resources, and intangible resources. In addition, physicians in private hospitals were found to be more satisfied with their job content, but they were less satisfied with work motivation and retention and intangible resources. In addition, physicians who worked in hospitals located in Taichung city reported that they were less satisfied with their tangible resources than the physicians working in hospitals outside of the city. Conclusion: This study focused on the satisfaction of physicians who had already left their respective hospitals instead of current retained physicians. From this study, it is our recommendation that hospital managers should pay closer attention to the real needs and expectations of the physicians they employ, and managers should consider adjusting their managerial perspectives when establishing new human resources policies or making decisions.
doi:10.7603/s40681-016-0023-3 pmid:27854049 pmcid:PMC5112183 fatcat:prufavzl7betdeiljfkkmjj5re

Training demands on clerk burnout: determining whether achievement goal motivation orientations matter

Chia-Der Lin, Blossom Yen-Ju Lin
2016 BMC Medical Education  
In the education field, learning experiences are considered learners' properties and are viewed as a key determinant in explaining learners' learning processes, especially for training novices such as clerks with varying levels of commitment to the medical profession. This study explored whether clerks' achievement goal motivation orientations might buffer the negative well-being to a certain extent, considering their training demands during clinical training. Methods: Ninety-four clerks at a
more » ... rtiary medical center were longitudinally traced during their 2-year clerkship spanning from September 2013 to April 2015. Web-based, validated, structured, self-administered questionnaires were used to evaluate the clerks' properties of achievement goal motivation orientation and personal background at the beginning of the clerkship. Regular surveys were conducted to evaluate their perceptions of training demands and burnout at each specialty rotation. Overall, 2230 responses were analyzed, and linear mixed-effects models were used to examine the repeated measures of the clerks. Results: The results revealed that higher perceived psychological and physical demands of training were related to higher perceived burnout during the 2-year clerkship. Although both the clerks' task and ego orientations were related to reduced burnout (direct effects), only task orientation was indicated to exert a buffering effect on their perception of physical demands on burnout in the 1st year of the clerkship. Conclusions: Considering the negative effects of training demands (psychological and physical), we observed a limited effect of the task achievement motivation orientation of medical students; therefore, additional studies might focus on strategies to facilitate medical students in clerkships in addressing both the psychological and physical demands inherent in training workplaces to improve their learning experience and well-being.
doi:10.1186/s12909-016-0742-x pmid:27549217 pmcid:PMC4994176 fatcat:h5y2vztnzrdtrayylsx5ghiu2e

Stair-Walking Performance in Adolescents with Intellectual Disabilities

Wann-Yun Shieh, Yan-Ying Ju, Yu-Chun Yu, Che-Kuan Lin, Yen-Tzu Lin, Hsin-Yi Cheng
2016 Sensors  
Yu-Chun Yu, Che-Kuan Lin, and Yen-Tzu Lin organized the clinical evaluation and data collection process. All of these authors contributed equally to the presentation and writing of this paper.  ...  Hsin-Yi Kathy Cheng and Yan-Ying Ju designed and monitored the whole experiment, and conducted clinical evaluation for all participants.  ... 
doi:10.3390/s16071066 pmid:27409621 pmcid:PMC4970113 fatcat:aphhwr24jndb3hgzth3lxuyo6u

High-Efficiency Ultrathin Si-Based Solar Cells by Cascading Dilute-Nitride GaNAsP

Yen-Ju Lin, David Jui-Yang Feng, Tzy-Rong Lin
2021 Materials  
Thin-film solar cells are currently an important research subject. In this study, a lattice-matched GaNAsP/Si tandem cell was designed. We adopted the drift-diffusion model to analyze the power conversion efficiency (PCE) of the solar cell. To find the maximum solar cell PCE, the recombination terms and the interlayer between subcells was omitted. For an optimal tandem cell PCE, this study analyzed the mole fraction combinations of GaNAsP and the thickness combinations between the GaNAsP and
more » ... Si subcells of the tandem cell. Our results showed the superiority of the tandem cell over the Si cell. The 4.5 μm tandem cell had a 12.7% PCE, the same as that of the 10.7 μm Si cell. The 11.5 μm tandem cell had 20.2% PCE, while the 11.5 μm Si cell processed 12.7% PCE. We also analyzed the Si subcell thickness ratio of sub-12 μm tandem cells for maximum PCE. The tandem cell with a thickness between 40% to 70% of a Si cell would have a max PCE. The ratio depended on the tandem cell thickness. We conclude that the lattice-matched GaNAsP/Si tandem cell has potential for ultrathin thin Si-based solar cell applications.
doi:10.3390/ma14237415 pmid:34885569 fatcat:tiidiy2qv5f2hdvbw5a7yzavqq

MoS2 with Stable Photoluminescence Enhancement under Stretching via Plasmonic Surface Lattice Resonance

Yen-Ju Chiang, Tsan-Wen Lu, Pin-Ruei Huang, Shih-Yen Lin, Po-Tsung Lee
2021 Nanomaterials  
In this study, by combining a large-area MoS2 monolayer with silver plasmonic nanostructures in a deformable polydimethylsiloxane substrate, we theoretically and experimentally studied the photoluminescence (PL) enhancement of MoS2 by surface lattice resonance (SLR) modes of different silver plasmonic nanostructures. We also observed the stable PL enhancement of MoS2 by silver nanodisc arrays under differently applied stretching strains, caused by the mechanical holding effect of the MoS2
more » ... yer. We believe the results presented herein can guarantee the possibility of stably enhancing the light emission of transition metal dichalcogenides using SLR modes in a deformable platform.
doi:10.3390/nano11071698 fatcat:pmpmitim3jgnhh3yztql3blntu
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