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In this study, the eIF-4A gene was isolated and identified from the A. pernyi pupal fulllength cDNA library (Li et al. 2009 ). ... From an A. pernyi pupal full-length cDNA library (Li et al. 2009 ), based on SMART (switching mechanism at 5 0 -end of RNA transcript) method, one EST encoding eIF-4A homolog was isolated by random sequencing ...doi:10.1093/jisesa/ieu030 pmid:25480968 pmcid:PMC5633915 fatcat:b62h6dcwq5ee7kfx4gb5kfbsda
The dendrite growth of Li anodes severely degrades the performance of lithium-oxygen (Li-O2) batteries. ... direct contact with Li metal. ... (d) Li + depletion time tests in symmetric Li/Li batteries at 200 μA. (e) Ge 3d XPS spectrum of HSE disassembled from symmetric Li/Li battery after 30 cycles. ...doi:10.1093/nsr/nwaa150 pmid:34691570 pmcid:PMC8288355 fatcat:7z7rycvihbfd5babrfbesefpki
When we consider only the CME from the initial condition, ζ = 0; when we consider only the fluctuation effect ζ = 1 2 ; otherwise, ζ lies between them. ...arXiv:2004.04440v1 fatcat:ga7hdkg5kvcyhno4xz3lbhnr6e
The secondary antibody used was IRdye800cW goat anti-rabbit antibody (1:20,000; LI-cOR Biosciences). ... Finally, labeled proteins were detected using a near-infrared imaging system (LI-cOR Biosciences) and analyzed using an image analyzer (Image Studio™ Table I . ...doi:10.3892/ijmm.2021.5019 pmid:34368862 pmcid:PMC8416143 fatcat:zjiw7oliwzgf3pucda555a2v5u
The SMC normal temperature reclaimed asphalt pavement (SMC-RAP) technology is a new kind of pavement regeneration technology, which could raise the usage of the reclaimed materials from the old road up to 60%, and would bring a significant economic and environmental benefits to the society. The mix design method and road performance evaluation of this new material has been researched by this paper.doi:10.12783/dtetr/ecar2018/26347 fatcat:aktmxs7cufcq7gjdgfgbpheaie
Malignant melanoma involving the respiratory tract is nearly always metastatic in origin, and primary tumors are very rare. To our knowledge, about 30 cases have been reported in the English literature, one of which involved multiple brain metastases. Here, we report two cases of primary pulmonary malignant melanoma. The first case, which occurred in a 52-year-old Chinese female patient who died 4 months after the initial diagnosis, involved rapid intrapulmonary and intracranial metastases. Thedoi:10.1186/1746-1596-7-123 pmid:22992473 pmcid:PMC3502413 fatcat:b3qxafhkp5hgnlccnbt22uncii
more »... second patient, a 65-year-old female, underwent surgical excision, and clinical examination, histopathological characteristics, and immunohistochemical features supported the diagnosis of pulmonary malignant melanoma. No evidence for recurrence and/or metastasis has been found more than one year after the initial surgery. To establish the diagnosis of primary pulmonary malignant melanoma, any extrapulmonary origin must be excluded by detailed examination. Moreover, the tumor should be removed surgically whether it occurs as a single lesion or multiple lesions. Virtual slide: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/ 1480477335765055.
Minimal deviation adenocarcinoma (MDA) of the uterine cervix is defined as an extremely well differentiated variant of cervical adenocarcinoma, with well-formed glands that resemble benign glands but show distinct nuclear anaplasia or evidence of stromal invasion. Thus, MDA is difficult to differentiate from other cervical hyperplastic lesions. Monoclonality is a major characteristic of most tumors, whereas normal tissue and reactive hyperplasia are polyclonal. Methods: The clinicopathologicaldoi:10.1186/1746-1596-5-25 pmid:20416098 pmcid:PMC2877003 fatcat:lhgd4tdysjhdbf4z3hcsjq7qfy
more »... eatures and clonality of MDA were investigated using laser microdissection and a clonality assay based on the polymorphism of androgen receptor (AR) and X-chromosomal inactivation mosaicism in female somatic tissues. Results: The results demonstrated that the glands were positive for CEA, Ki-67, and p53 and negative for estrogen receptor (ER), progesterone receptor (PR), and high-risk human papilloma virus (HPV) DNA. The index of proliferation for Ki-67 was more than 50%. However, the stromal cells were positive for ER, PR, vimentin, and SM-actin. The clonal assay showed that MDA was monoclonal. Thus, our findings indicate that MDA is a true neoplasm but is not associated with high-risk HPV. Conclusions: Diagnosis of MDA depends mainly on its clinical manifestations, the pathological feature that MDA glands are located deeper than the lower level of normal endocervical glands, and immunostaining.
Mosquito-borne flaviviruses infect both mammals and mosquitoes. RNA interference (RNAi) has been demonstrated as an anti-flavivirus mechanism in mosquitoes; however, whether and how flaviviruses induce and antagonize RNAi-mediated antiviral immunity in mammals remains unknown. We show that the nonstructural protein NS2A of dengue virus-2 (DENV2) act as a viral suppressor of RNAi (VSR). When NS2A-mediated RNAi suppression was disabled, the resulting mutant DENV2 induced Dicer-dependentdoi:10.1126/sciadv.aax7989 pmid:32076641 pmcid:PMC7002134 fatcat:vheurxvzonffrcksf3uwqfczbe
more »... of abundant DENV2-derived siRNAs in differentiated mammalian cells. VSR-disabled DENV2 showed severe replication defects in mosquito and mammalian cells and in mice that were rescued by RNAi deficiency. Moreover, NS2As of multiple flaviviruses act as VSRs in vitro and during viral infection in both organisms. Overall, our findings demonstrate that antiviral RNAi can be induced by flavivirus, while flavivirus uses NS2A as a bona fide VSR to evade RNAi in mammals and mosquitoes, highlighting the importance of RNAi in flaviviral vector-host life cycles.
Malignant triton tumor (MTT) is defined as malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation. Intracranial MTT is extremely rare, and only four cases have been reported in the literature. Here, we report a case of MTT occurring in the cerebellopontine angle, and describe its histopathological characteristics, immunohistochemical features, and prognosis. Virtual slides: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/ vs/1336227313684480doi:10.1186/1746-1596-7-43 pmid:22515616 pmcid:PMC3438054 fatcat:knknuyhfzbhmbl23r2ezrlq5vu
Objective: To prepare the diclofenac sodium pH sensitive gel for eyes (DS-pH sensitive gel). Methods: It's used for the index that viscosity under non-physiological conditions and physiological conditions were less than 1100mPa·s and more than 2500mPa·s respectively, the dosage ranges of Carbopol 980 and HPMC were screened. The formula of DS-pH sensitive gel was optimized by orthogonal test. Results: The best formula contained Carbopol 980 0.35g, HPMC 1.0g, ethylparaben 0.01 g, mannitol 5g,doi:10.12783/dtetr/mcee2017/15783 fatcat:vlv3pa7cyrhhlk7l774dbjxufy
more »... ofenac sodium 100mg, and water for injection 100mL. Conclusion: The DS-pH sensitive gel was prepared successfully.
5.6 ± 0.6 b 6.4 ± 0.7 b 12.5 ± 1.0 b Low dose of TALH group 0.05 6.0 ± 0.6 b 7.1 ± 0.6 a 13.0 ± 0.8 a Data are mean ± SD; n=10; Compared with the model group, a p<0.05, b p<0.01 Author Info Miao ...doi:10.3329/bjp.v11is1.25633 fatcat:elhtrtvddrafpnm3qaisufitha
Disclosure Song Yang and Kun Li are co-first authors. ...doi:10.1155/2019/5907361 pmid:31737670 pmcid:PMC6815587 fatcat:chkvakbqcjdhrh33wqwrjwr5am
5.6 ± 0.6 b 6.4 ± 0.7 b 12.5 ± 1.0 b Low dose of TALH group 0.05 6.0 ± 0.6 b 7.1 ± 0.6 a 13.0 ± 0.8 a Data are mean ± SD; n=10; Compared with the model group, a p<0.05, b p<0.01 Author Info Miao ...doi:10.3329/bjp.v11i0.25633 fatcat:zk53bwscxvekpld35qeomn5ege
Sentence generation with soft constrains is also related to controlling latent features of a sentence (Prabhumoye et al. 2018; Li et al. 2018) , such as the meaning and sentiment. ...arXiv:1811.10996v1 fatcat:xlhzlpuorvhqtofnzhw2chly7q
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