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Author's contributions All by Xuejian Wang. ...doi:10.1186/s41016-017-0073-8 fatcat:hudhuyo7g5fjxn36m6mlvllqce
: Traumatic bilateral multiple ribs fractures during pregnancy is a rare event. In this case author reports 41 years old multigravida women in 2nd trimester of pregnancy, presenting to hospital after a road traffic accident in a vulnerable condition. Physician must make sure the probable implications of the patient and the fetus. Accurate diagnosis is made using highly sensitive and specific computed tomography. Severely displaced ribs are fixed by open reduction internal fixation and remainingdoi:10.5281/zenodo.4276531 fatcat:icheomuwcjchpapnqnikqlxh5i
more »... non-displaced ribs can be healed by conservative treatment. Proper analgesics are prescribed to manage pain pre and postoperatively. Physicians should cope with patient and family in making an effort to protect the child and continuing the pregnancy followed by regular fetal monitoring tests.
Authors' contributions Conceived and designed: Xuejian Wang, Yang Chen. Performed: Zhifeng Wang, Ming Qian. Analyzed the data: Xuejian Wang. Wrote the paper: Xuejian Wang. ...doi:10.1186/s41016-017-0076-5 fatcat:bekqt244hfdyrnznak2ae74eey
Nonketotic hyperglycemia-related seizures (NKH) are rare. We report a case of NKH-related seizures in a patient following a traumatic brain injury.doi:10.1016/j.ebcr.2013.03.001 pmid:25667834 pmcid:PMC4150656 fatcat:ogpoao4nxbhrbmc6ggyxp5vpyq
Reviewing the literature, we found that brain Xuejian W. et al: Intracerebellar Hemispheres Schwannoma parenchyma schwannomas are mainly located in the upper tentorium and less than ten cases occurred ...doi:10.5137/1019-5149.jtn.5514-11.2 pmid:24101280 fatcat:5xj62w5trrcqremfdvysdfhwvy
Shock and Vibration
To protect structures from short duration shock load in various engineering applications, a novel energy conversion mechanism with concept design is proposed. Different from conventional methods with cellular solid/structure dissipating input translational kinetic energy to plastic strain energy with large compressive deformation, the proposed approach converts part of incident translational kinetic energy to rotational kinetic energy, which is not detrimental to the protected structure. Thedoi:10.1155/2018/9136867 fatcat:ysjf4rn5ljaa7g6hifmiwyffl4
more »... hanism of energy conversion is analyzed and formulated, with key factors governing the conversion efficiency identified and discussed, which sheds light on alternative approach for short duration load mitigation.
Model combination, often regarded as a key sub-field of ensemble learning, has been widely used in both academic research and industry applications. To facilitate this process, we propose and implement an easy-to-use Python toolkit, combo, to aggregate models and scores under various scenarios, including classification, clustering, and anomaly detection. In a nutshell, combo provides a unified and consistent way to combine both raw and pretrained models from popular machine learning libraries,arXiv:1910.07988v2 fatcat:vv25ofpzknf77eb6w7wwxizuva
more »... .g., scikit-learn, XGBoost, and LightGBM. With accessibility and robustness in mind, combo is designed with detailed documentation, interactive examples, continuous integration, code coverage, and maintainability check; it can be installed easily through Python Package Index (PyPI) or https://github.com/yzhao062/combo.
Pituitary tumors do not pose a threat to life but can cause visual disturbances and serious clinical syndromes, such as infertility and metabolic syndrome. Therefore, screening of key genes involved in the occurrence and development of pituitary tumors can provide new targets for the treatment of pituitary tumors. The aim of the present study was to investigate the molecular mechanism of long non‑coding (lnc.) RNA maternally expressed 3 (MEG3) in cell proliferation, apoptosis anddoi:10.3892/or.2021.7991 pmid:33649837 pmcid:PMC7934213 fatcat:2uhoqrfqwrbzfijvuhqizwvbra
more »... nchymal transition (EMT) processes of pituitary tumor. Tissue samples were obtained from 34 patients who underwent surgical treatment of pituitary tumors. Pituitary tumor cells (GH3 and MMQ) were transfected with pcDNA3.1(+)‑MEG3, short hairpin (sh)MEG3, microRNA (miR)‑23‑3p inhibitor or their controls using Lipofectamine® 2000. Reverse transcription‑quantitative PCR and western blot analyses were used to detect the levels of MEG3, miR‑23b‑3p and FOXO4, as well as proliferation‑, apoptosis‑ and EMT‑associated genes and proteins. Cell Counting Kit‑8 and flow cytometry assays were performed to detect proliferation and apoptosis, and Transwell assay was undertaken to assess invasion and migration. Luciferase reporter and RNA pulldown assays were performed to verify the binding between lncRNA MEG3, miR‑23b‑3p and FOXO4. Pearson's correlation analysis was used to analyze the correlation between expression levels of MEG3, miR‑23b‑3p and FOXO4. lncRNA MEG3 was expressed at lower levels in pituitary tumor tissues and cells. Overexpression of lncRNA MEG3 inhibited proliferation, invasion and migration and accelerated apoptosis of pituitary tumor cells. lncRNA MEG3 negatively regulated miR‑23b‑3p expression levels, while miR‑23b‑3p negatively regulated FOXO4 expression levels. Overexpression of lncRNA MEG3 inhibited the EMT process in pituitary tumor cells. miR‑23‑3p inhibitor rescued the effect of shMEG3 on proliferation, invasion, migration, apoptosis and the EMT process in pituitary tumor cells. lncRNA MEG3 inhibited pituitary tumor development by participating in cell proliferation, apoptosis and the EMT process, which may present a novel target for pituitary tumor treatment.
(Xuejian Xie); software, X.W.; validation, Y.P., X.H. (Xiaobo Hu) and X.X. (Xiangang Xu); formal analysis, X.H. (Xiaotong Han); investigation, X.H. ... A detailed description of the chamber geometry and the deposition reaction system is given by Wang  . ...doi:10.3390/ma13204510 pmid:33053712 fatcat:wx7x6pw4bvhpbdkmgz7dura4xm
) (Zhao, Zhang, and Wang 2013; Kawale et al. 2015; Wang, Wu, and Wang 2017) . ... Related Work and Background Advanced Recommendation Algorithms for IRS MAB-based Recommendation A group of works (Li et al. 2010; Chapelle and Li 2011; Zhao, Zhang, and Wang 2013; Wang, Wu, and Wang 2016 ...arXiv:1811.05869v1 fatcat:6ulcdo4py5crbaksrbubxghmqm
Cerebrospinal Fluid (CSF) A variable-pressure ventriculiperitoneal shunt were used in Xuejian Wang et al.: Diagnosis and Treatment of Low Intracranial Pressure Hydrocephalus all five cases (Medos-Codman ...doi:10.11648/j.ijnpt.20170304.13 fatcat:y7oizifg2na4djhhrpe7gptuwe
Primary extragonadal germ cell tumors are rare, and 60% of such cases are seminomas. While the tumors can occur in the mediastinum, thymus, retroperitoneal organs and pineal gland, seminoma originating in the prostate tissue is extremely rare. The present study reports the case of a 54-year-old male with prostate seminoma. The patient was followed up at the First Affiliated Hospital of Dalian Medical University (Dalian, Liaoning, China) from 2001 onwards. The patient received chemotherapy withdoi:10.3892/ol.2015.3592 pmid:26622843 pmcid:PMC4579977 fatcat:dusubxgcvfbctiwmcb2axmyqxq
more »... yclophosphamide following total resection of the pelvic organs, pelvic lymph node dissection, continent detenial cecum-ascending colic bladder and orchidectomy. The patient experienced considerable post-operative quality of life for >10 years and the disease did not reappear. The study indicated that extragonadal seminoma is sensitive to chemotherapy, and that radical surgery and post-operative adjuvant chemotherapy with cyclophosphamide is a reasonable and feasible treatment method.
apoptotic stimuli cause cytochrome c release from mitochondria, and this in turn induces a series of biochemical reactions that result in caspase activation and subsequent cell apoptosis (Jiang and Wang ...doi:10.1016/j.virol.2015.03.037 pmid:25863179 fatcat:tjym5ucu4ffrvhrvgjhtrgiy2q
Wang Y. et al: Controlled Decompression for Head Injury ... After the surgery, delayed epidural hema- Wang Y. et al: Controlled Decompression for Head Injury Operative Safety The incidence of acute brain swelling was significantly higher in the decompressive ... Yuhai Wang and Chunli Wang contributed equally to work. ...doi:10.5137/1019-5149.jtn.8135-13.1 pmid:24831363 fatcat:fvobssb7pzchbdthbyeqjvvekm
The aim of the current study was to investigate the effects and the molecular mechanisms of ARK5 in ovarian cancer cell invasion. The plasmid pGCsilencerU6/GFP/Neo-RNAi-ARK5 and the control vector with a scramble sequence were transfected into SKOV3 cells to establish ARK5-deficient SKOV3 cells (siARK5/SKOV3) and a control cell line (Scr/SKOV3), respectively. Reverse transcription-polymerase chain reaction (RT-PCR) and Western blot analysis were used to determine the mRNA and protein expressiondoi:10.3892/mmr.2019.9901 fatcat:27yj2xq73fb3xokhm6bng3e6mq
more »... levels of ARK5. Migration and invasion abilities of SKOV3 cells were determined in chemotaxis and invasion assays, respectively. The epidermal growth factor-1 (EGF-1)-induced expression of matrix metallopeptidase (MMP)-2 and MMP-9, epithelial-mesenchymal transition (EMT) and phosphorylation of mechanistic target of rapamycin kinase (mTOR) in siARK5/SKOV3 and Scr/SKOV3 cells were detected by western blot. RT-PCR and western blot analyses demonstrated that the expression of ARK5 was significantly downregulated in siARK5/SKOV3 cells at the mRNA and protein levels (P<0.01). The migration and invasion abilities of siARK5/SKOV3 cells were markedly decreased compared with Scr/SKOV3 cells (P<0.01). In addition, the results demonstrated that EGF-1-induced expression of MMP-2 and MMP-9, EMT and phosphorylation of mTOR were suppressed in siARK5/SKOV3 cells as compared with Scr/SKOV3 cells (P<0.01). The current study demonstrated that ARK5 is a critical factor involved in SKOV3 cell invasion and ARK5 increases invasive potential by promoting EMT and activating the Akt-mTOR-MMPs pathway.
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