A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
With the proliferation of mobile devices, location-based services (LBS) have penetrated into our daily life in recent years. In an LBS system, the users check in at different venues to acquire rewards such as virtual points or real-world coupons/discounts, and easily share with their friends the recent activities. While these rewards benefit benign users a lot, they are incentives for malicious users to cheat on their locations. Recent researches have revealed that location cheating can bedoi:10.1016/j.procs.2014.07.041 fatcat:wua6nf5ul5bepk2dmk4zkfwlcu
more »... hed automatically on a large scale at ease. In current practice, the defense against location cheating relies on the server side solution, which has been proven to be insufficient. In this paper, we propose a novel verification system named WiLoVe. It maps the physical area of a venue to the local WiFi coverage and involves the venue owner as the verifier, hence utilizes the user's capability of one-hop communication with the verifier to verify the user's presence at the venue. In this work, we implement the verifier as an independent application, which can easily be installed on the venue owner's existing devices (laptops, cellphones, etc.). Hence, no additional hardware is needed. An adaptive algorithm is designed to defend against proxy attacks based on the check-in delay. Extensive experiments show that WiLoVe achieves low false rate, as well as consistent user experience, acceptable power consumption, and good applicability to different WiFi environments.
The aim of the present study was to investigate the association between the dynamic intensity-modulated radiation therapy planned γ analysis passing rate and respiratory amplitude (A) and period (T) for different tumor volumes. A total of 30 patients with malignant lung tumors were divided into three groups: A; B; and C. The average tumor volumes (V) in the A, B and C groups were 635, 402 and 213 cm 3 , respectively. The simulated A values were set at 0, 5, 10, 15, 20 and 25 mm. The T valuesdoi:10.3892/ol.2018.8724 pmid:29963170 pmcid:PMC6019885 fatcat:no4qyeavkvettcauq6wh4boqua
more »... e set at 4, 5 and 6 sec. The γ analysis passing rate was calculated under different conditions (dose difference, 3%; distance difference, 3 mm). Compared with the γ analysis passing rate in the A group (A=0, static; T=4, 5, 6 sec), the γ analysis passing rate deviation (A=5 mm) was <3.3%. However, this difference was not statistically significant (P>0.05). With a gradual increase in A value, the passing rate decreased. The deviation between the 3 groups was <2.5% at the same A value (T=4, 5 and 6 sec). A descending trend of passing rate with increased A value was revealed. At the same A and T values, the passing rate decreased with decreased tumor volume. At the same tumor volume, the passing rate decreased when the A value increased. The respiratory cycle was not demonstrated to be associated with the passing rate. Overall, these results suggest that the A value should be controlled in clinical radiotherapy.
Gao Liugang and Ni Xinye conceived the experiments, GaoLiugang, Sun Hongfei, Ni Xinye and Fang Mingming performed the experimental characterizations. Ni Xinye and Lin Tao analysed the results. ... Gao Liugang, Ni Xinye and Fang Mingming revised the manuscript. All authors discussed the results and have given approval to the final version of the manuscript. ...doi:10.1038/srep37608 pmid:27869185 pmcid:PMC5116646 fatcat:22ovx67qkzhnxouv4nmnmlhmv4
In this paper, we design a set of multi-objective constrained optimization problems (MCOPs) and propose a new repair operator to address them. The proposed repair operator is used to fix the solutions that violate the box constraints. More specifically, it employs a reversed correction strategy that can effectively avoid the population falling into local optimum. In addition, we integrate the proposed repair operator into two classical multi-objective evolutionary algorithms MOEA/D and NSGA-II.arXiv:1504.00154v1 fatcat:wlxqk3up5nhm7anmhmuevhgnge
more »... The proposed repair operator is compared with other two kinds of commonly used repair operators on benchmark problems CTPs and MCOPs. The experiment results demonstrate that our proposed approach is very effective in terms of convergence and diversity.
Link prediction in complex networks predicts the possibility of link generation between two nodes that have not been linked yet in the network, based on known network structure and attributes. It can be applied in various fields, such as friend recommendation in social networks and prediction of protein-protein interaction in biology. However, in the social network, link prediction may raise concerns about privacy and security, because, through link prediction algorithms, criminals can predictdoi:10.1155/2020/6148273 doaj:89b19067e3e34611b867f4fab80b96e7 fatcat:mdurntli2jb4ldnezdg6v4je6q
more »... he friends of an account user and may even further discover private information such as the address and bank accounts. Therefore, it is urgent to develop a strategy to prevent being identified by link prediction algorithms and protect privacy, utilizing perturbation on network structure at a low cost, including changing and adding edges. This article mainly focuses on the influence of network structural preference perturbation through deletion on link prediction. According to a large number of experiments on the various real networks, edges between large-small degree nodes and medium-medium degree nodes have the most significant impact on the quality of link prediction.
The GPS trajectory databases serve as bases for many intelligent applications that need to extract some trajectories for future processing or mining. When doing such tasks, spatio-temporal range queries based methods, which find all sub-trajectories within the given spatial extent and time interval, are commonly used. However, the history trajectory indexes of such methods suffer from two problems. First, temporal and spatial factors are not considered simutaneously, resulting in lowdoi:10.1587/transinf.e96.d.643 fatcat:4a6jqwd64beatbvpg4ucpexq7q
more »... when processing spatio-temporal queries. Second, the efficiency of indexes is sensitive to query size. The query performance changes dramatically as the query size changed. This paper proposes workload-aware Adaptive OcTree based Trajectory clustering Index (ATTI) aiming at optimizing trajectory storage and index performance. The contributions are three-folds. First, the distribution and time delay of the trajectory storage are introduced into the cost model of spatio-temporal range query; Second, the distribution of spatial division is dynamically adjusted based on GPS update workload; Third, the query workload adaptive mechanism is proposed based on virtual OcTree forest. A wide range of experiments are carried out over Microsoft GeoLife project dataset, and the results show that query delay of ATTI could be about 50% shorter than that of the nested index.
Copyright © 2020 Feng, Yu, Chiu and Lin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). ...doi:10.3389/fpubh.2020.00168 pmid:32582601 pmcid:PMC7297082 fatcat:iuap7353crh4leeqy6ajvnddv4
Parasites & Vectors
Schistosoma japonicum is a parasitic flatworm that causes human schistosomiasis. Secreted extracellular vesicles (EVs) play a key role in pathogen-host interfaces. Previous studies have shown that S. japonicum adult worms can release microRNA (miRNA)-containing EVs, which can transfer their cargo to mammalian cells and regulate gene expression in recipient cells. Tissue-trapped eggs are generally considered the major contributor to the severe pathology of schistosomiasis; however, thedoi:10.1186/s13071-016-1845-2 pmid:27825390 pmcid:PMC5101684 fatcat:sofcwelgqzhsbokxa7rr3djr6u
more »... ns between the host and parasite in this critical stage remain largely unknown. Methods: The culture medium for S. japonicum eggs in vitro was used to isolate EVs. Transmission electron microscopy (TEM) analysis was used to confirm that vesicles produced by the eggs were EVs based on size and morphology. Total RNA extracted from EVs was analyzed by Solexa technology to determine the miRNA profile. The in vitro internalization of the EVs by mammalian cells was analyzed by confocal microscopy. The presence of EVs associated miRNAs in the primary hepatocytes of infected mice was determined by quantitative real-time PCR (qRT-PCR). Results: EVs were isolated from the culture medium of in vitro cultivated S. japonicum eggs. TEM analysis confirmed that nanosized vesicles were present in the culture medium. RNA-seq analysis showed that the egg-derived EVs contained small non-coding RNA (sncRNA) populations including miRNAs, suggesting a potential role in host manipulation. This study further showed that Hepa1-6, a murine liver cell line, internalized the purified EVs and their cargo miRNAs that were detectable in the primary hepatocytes of mice infected with S. japonicum. Conclusions: Schistosoma japonicum eggs can release miRNA-containing EVs, and the EVs can transfer their cargo to recipient cells in vitro. These results demonstrate the regulatory potential of S. japonicum egg EVs at the parasite-host interface.
Dose distribution was calculated and analyzed on the basis of 16-bit computed tomography (CT) images in order to investigate the effect of scanning conditions on CT for metal implants. Stainless steel and titanium rods were inserted into a phantom, and CT images were obtained by scanning the phantom under various scanning conditions: i) Fixed tube current of 230 mA and tube voltages of 100, 120, and 140 kV; and ii) fixed tube voltage of 120 kV and tube currents of 180, 230, and 280 mA. The CTdoi:10.3892/ol.2017.7586 pmid:29434946 pmcid:PMC5777373 fatcat:mldi75klpne2fotuvl7qwh7otu
more »... lue of the metal rod was examined and corrected. In a Varian treatment planning system, a treatment plan was designed on the basis of the CT images obtained under the set scanning conditions. The dose distributions in the phantom were then calculated and compared. The CT value of the metal area slightly changed upon tube current alteration. The dose distribution in the phantom was also similar. The maximum CT values of the stainless steel rod were 14,568, 14,127 and 13,295 HU when the tube voltages were modified to 100, 120, and 140 kV, respectively. The corresponding CT values of the titanium rod were 9,420, 8,140 and 7,310 HU. The dose distribution of the radiotherapy plan changed significantly as the tube voltage varied. Compared with the reference dose, the respective maximum dose differences of the stainless steel and titanium rods in the phantom were 5.70, and 6.62% when the tube voltage varied. The changes in tube currents resulted in a maximum dose error of <1% for stainless steel and titanium. In CT imaging, changes in tube voltages can significantly alter the CT values of metal implants. Thus, this can lead to large errors in radiotherapy dose distributions.
Allergic rhinitis is a common respiratory disease. Acupuncture is used to treat it in traditional Chinese medicine, and generally, the L120, ST2 and ST36 acupoints are selected in clinical practice. We report a new method of acupuncture at the sphenopalatine acupoint (SPA) for treatment of persistent allergic rhinitis (PAR). The effect of this treatment was investigated using two different needling depths. The efficacy of this treatment was associated with accurate stimulation of thedoi:10.1186/s13063-017-2339-z pmid:29325594 pmcid:PMC5765676 fatcat:6rxh5myofjc3djyvsvq3br4bwy
more »... ine ganglion (SPG). Methods/Design: A total of 61 patients diagnosed with PAR were randomly allocated to either the acupuncture or the sham acupuncture group. The difference between the groups was the needle depth when acupuncture was administered, which was 50 mm and 20 mm. Alteration in total nasal symptom score (TNSS) was the primary outcome. Quality of life, medication dosages and adverse events were secondary outcomes, measured using the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ). Confidence assessment was performed to evaluate data from the treatment and follow-up periods. Results: Results were: (1) average TNSS in the treatment group was significantly lower than in the control group at week 4 (median and 25th and 75th percentiles were 5.00 (4.00, 7.00) and 8.00 (7.00, 10.00), respectively (P < 0.001)). However, scores in the two groups were not significantly different at week 12; (2) quality of life (RQLQ) was significantly improved at week 2 in the treatment group compared to the control group (scores of 35.47 ± 8.20 and 45.48 ± 8.84; P < 0.001); (3) during the follow-up period, the medication dosage in the treatment group was much lower than in the control group (3.64 ± 1.45 and 6.14 ± 2.34; P < 0.05); and (4) no adverse events were observed in either group during treatment. Conclusions: This pilot study revealed a profound effect of acupuncture at the SPA on prevention of PAR development. The TNSS in the treatment group (needle depth 50 mm), was significantly lower than in the control group (needle depth of only 20 mm). Our result demonstrates that performing acupuncture directly at the SPA to stimulate the SPG is an effective method to treat PAR.
This study aimed to analyze the influence of the radiation field size on the passing rate of the treatment planning system using MatriXX if the field irradiated the circuit.Two sets of static fields which were 10 cm and 30 cm in the left-right direction (X), and was 31 cm to 40 cm in gun-target direction (Y) were designed. In these fields, the gantry was 0 and the monitor units were 200 MU. Two plans from an esophagus carcinoma patient with a planning target volume of 86.4 cm and a cervicaldoi:10.1097/md.0000000000016536 pmid:31348271 pmcid:PMC6709154 fatcat:q4z3x5vufvgjho4aa3rbhk43lu
more »... inoma patient with a planning target volume (PTV) of 2094.1 cm were chosen. The passing rates of these plans were gained without and with protecting the circuit area from lead alloys. The gamma analysis was used and the standard was set to 3%/3 mm.The verification passing rate decreased from 95.0% to 69.2% when X was 10 cm while Y increased from 31 cm to 40 cm. With the protection from low melting point lead alloys, the passing rate was from 96.2% to 89.6%. The results of the second set of plans without lead alloys were similar but the passing rate decreased more sharply. The passing rates of the 2 patients were 99.5% and 57.1%. With the protection of the lead alloys, their passing rates were 99.8% and 72.1%, respectively.The results showed that with the increase of the radiation field size in the Y direction, more areas were irradiated in the circuit, and the passing rate gradually decreases and dropped sharply at a certain threshold. After putting lead alloys above the circuit, the passing rate was much better in the static field but was still less than 90% in the second patient volumetric modulated arc therapy (VMAT) because the circuit was irradiate in other directions. In daily QA, we should pay attention to these patients with long size tumor.
Compared with traditional itinerary planning, intention oriented itinerary recommendation can provide more flexible activity planning without the user pre-determined destinations and is specially helpful for those strangers in unfamiliar environment. Rank and classification of points of interest (POI) from location based social networks (LBSN) are used to indicate different user intentions. Mining on physical trajectories of vehicles can provide exact civil traffic information for pathdoi:10.1145/2346496.2346508 dblp:conf/kdd/MengLW12 fatcat:3wa5qbuu2vfxxf3xclzalosary
more »... In this paper, a POI category-based itinerary recommendation framework combining physical trajectories with LBSN is proposed. Specifically, a Voronoi graph based GPS trajectory analysis method is proposed to build traffic information networks, and an ant colony algorithm for multi-object optimization is also implemented to find the most appropriate itineraries. We conduct experiments on datasets from FourSquare and Geo-Life project. A test on satisfaction of recommended items is also performed. Results show that the satisfaction reaches 80% in average.
., 2010; Lin et al., 2020; Passricha et al., 2020; Yuchun et al., 2021) ; however, the function of a unique group of RLKs, known as WAKs, in salt tolerance remains unclear. ...doi:10.3389/fpls.2021.751965 pmid:34675955 pmcid:PMC8523997 fatcat:wgobjgvpwrbjxnjt6z4u7j6r5u
This study aimed to investigate the reliability of pseudo-computed tomography (pseudo-CT) imaging based on ultrasound (US) deformation fields under different binary masks in radiotherapy.We used 3-dimensional (3D) CT and US images, including those acquired during CT simulation positioning, and cone-beam CT (CBCT) and US images acquired 1 week after treating 3 patients with cervical cancer. Image data of 3 different layers were selected from the US images, and 3D CT images of each patient weredoi:10.1097/md.0000000000012532 pmid:30235776 pmcid:PMC6160174 fatcat:6abd33vb6nh6ll475lrsyvymem
more »... lected. For US image registration, the following were created and applied: binary masks of the region of interest overlapping (ROIO) between the US image based on simulation positioning and US image for positioning verification, region of interest (ROI), whole overlapping (wholeO), and whole imaging region (whole). Accordingly, the deformation field was obtained and applied to CT images (CTsim), and different pseudo-CT images were acquired. Similarities between the pseudo-CT and CBCT images were compared, and registration accuracies between pseudo-CT images under different binary masks and CTsim were compared and discussed.A pair t test was conducted to normalized mutual information values of the registration accuracy between the pseudo-CT image based on ROIO binary mask and CTsim with other methods (P < .05), and the difference was statistically significant. A pair t test of normalized gray mean-squared errors was also performed (P < .05), and the difference was statistically significant. The similarity function means between pseudo-CT, that is, based on ROIO, ROI, wholeO, whole, and no binary mask, and CBCT were 0.9084, 0.8365, 0.7800, 0.6830, and 0.5518, respectively.Pseudo-CT based on ROIO binary mask best matched with CTsim and achieved the highest similarity with CBCT.
The radiation transmission through the multileaf collimators is undesired in modern techniques such as volumetric modulated arc therapy (VMAT). According to identical plans, in this study, we aim to investigate the dosimetric impact of jaw tracking on the VMAT plans on two adjacent targets. Methods: Two treatment plans were designed for eight pelvic (cervical) patients with two targets using the same optimization parameters. The original plan (O-plan) used automatically selected jaw positions.doi:10.1186/s13014-019-1284-2 fatcat:suwgbagdrzaytegz6qhaq35b7y
more »... n the new plan (Fplan), the jaws were fixed to block two targets in two beams. The dosimetric parameters of the two plans were compared to evaluate the improvement of dose sparing for the body volume between two targets (named interOAR) in F-VMAT. Results: The mean dose of interOAR reduced significantly from 654.96 ± 113.38 cGy for O-VMAT, to 490.84 ± 80.26 cGy for F-VMAT (p = 0.018). The monitor units (MUs) in the F-plans were 1.49-fold higher than that in the O-plan. The F and O-plan performed similarly in target dose homogeneity. The differences in Dmax of spinal cord, Dmax of spinal cord planning organ at risk volume, and V20, V30, and V40 of the intestine were insignificant. Conclusions: VMAT plans with the fixed-jaw method can reduce the volume between two targets effectively. However, despite the plan quality, the method can only be used when the regular methods cannot reach the clinical requirements for critical organs because of additional MUs.
« Previous Showing results 1 — 15 out of 99 results