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Simplifying Electronic Data Capture in Clinical Trials: Workflow Embedded Image and Biosignal File Integration and Analysis via Web Services

Daniel Haak, Christian Samsel, Johan Gehlen, Stephan Jonas, Thomas M. Deserno
2014 Journal of digital imaging  
In this paper, an integrated workflow based on OpenClinica, one of the world's largest EDCS, is presented.  ...  3D data) have been established as surrogate endpoints in clinical trials.  ...  Acknowledgments This research was partly supported by European Foundation for the Study of Diabetes (EFSD 74550-94555).  ... 
doi:10.1007/s10278-014-9694-z pmid:24802371 pmcid:PMC4171435 fatcat:hfpze7qeu5b6hluhtld6ncnioi

Digital Imaging and Electronic Data Capture in Multi-Center Clinical Trials [chapter]

Thomas M. Deserno, Verena Deserno, Daniel Haak, Klaus Kabino
2015
in clinical trials lack PACS interfacing.  ...  We propose an open source-based architecture composed of OpenClinica, DCM4CHE, and Weasis for EDCS, PACS, and Viewer, respectively.  ...  The successive levels of EDCS/PACS integration provide increasing functionality in mutli-center trials.  ... 
doi:10.18154/rwth-2016-01260 fatcat:o4hdiyvx3fgpthmecr2roiljyu

Health—exploring complexity: an interdisciplinary systems approach HEC2016

Eva Grill, Martin Müller, Ulrich Mansmann
2016 European Journal of Epidemiology  
In addition, image-or signal-based surrogates (imaging biomarkers) are acquired increasingly in those trials.  ...  Currently, the (CommServ) interconnects: the clinical trial management system (CTMS), two electronic data capture systems (EDCS): OpenClinica for clinical trials and Google Web Toolkit (GWT)-based rare  ...  Material/methods Given a set of seed points P, a Web crawler extracts hyperlinks contained in P and traverses the directed graph of the Web [3] .  ... 
doi:10.1007/s10654-016-0183-1 pmid:27522353 fatcat:dcl3nbpygvh5fg7keri74h55ie

Meeting abstracts from the 5th International Clinical Trials Methodology Conference (ICTMC 2019)

2019 Trials  
Methods: We have developed a Picture Archiving and Communication System (PACS) for RAMPART, a cloud-based solution consisting on a web application, used to upload and manage images and generate reports  ...  in primary care based clinical trials.  ...  Discussion: The evidence base to support trial recruitment is poor.  ... 
doi:10.1186/s13063-019-3688-6 pmid:31639031 pmcid:PMC6805286 fatcat:arl4zrirdnho3bwxzg3a66hd24

Conference 2017: From Innovation to Patient Solution. An international symposium held jointly by CSPS and CC-CRS, May 10-12, 2017, Montréal, QC Canada

Beverley Christina Berekoff
2017 Journal of Pharmacy & Pharmaceutical Sciences  
Approaches to Improve Efficiency in Respiratory CareConference Sessions:Special Session: Innovation and Development of Modern Pharmaceuticals1.  ...  Jason Moffat, University of Toronto: Genome-scale CRISPR Screens and Protein Engineering for Target Discovery and TranslationMarcel Bally, BC Cancer Agency - CSPS Leadership Award: Lipids, Drugs and Metals  ...  College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada  ... 
doi:10.18433/j3p36g fatcat:qnw35hme6fa4jmcx6dbtgwspzm

UCD School of Medicine, Summer Student Research Awards 2017, 4th October 2017, UCD, Dublin, Ireland

2017 Irish Journal of Medical Science  
Juvenile idiopathic arthritis (JIA) is one of the most common causes of chronic musculoskeletal pain in youth, and can negatively impact quality of life 1;2 .  ...  The results demonstrate that there is a need to provide more information to youth and caregivers about a wide variety of pain management options, and to support youth and families when making these decisions  ...  It was hoped to elucidate the nature and specificity of this binding, and assess variation in IgM responses between protective and nonprotective vaccine trials.  ... 
doi:10.1007/s11845-017-1711-z pmid:29151243 fatcat:sg3q4wrhh5dnjnzbi5gwn527ca

D3.18 Fourth periodic report on JRP

WP3
2022 Zenodo  
of this task is also to upgrade the platform for automatic pathogen identification in order to support both human and veterinary clinical practice and disease outbreak investigations.  ...  Higher resistance proportions were mainly encountered in non-clinical isolates of broilers and turkeys and in clinical isolates of calves.  ...  Inclusion criteria were: clinical reports including case reports, case series, clinical trials, retrospective and prospective cases of confirmed human cerebral CE.  ... 
doi:10.5281/zenodo.6488954 fatcat:4ft7tb3wenbineukevwf3fdhia

Global Trends & Challenges in Water Science, Research and Management

Hong Li
2018 Water Intelligence Online  
Acknowledgement We thank the reviewers, Dr William Burgess, Prof Eberhard Braune and Mr Jude Cobbing, on improving the quality of this report.  ...  Acknowledgements Acknowledgements On behalf of the Management Committee, the author acknowledges James Barnard, Burkhard Teichgräber and Jiri Wanner for their valuable contributions.  ...  Acceptance of this basic premise will lead to a higher level of confidence in data from other trials and less need to conduct local trials.  ... 
doi:10.2166/9781780408378 fatcat:kxjd2z5onvethbxwqa5syeu4le

95. Jahrestagung der Deutschen Gesellschaft für Pathologie e. V

2011 Der Pathologe  
So-015 Microarray-based amplification and detection of microRNAs (miRNAs) by NASBA (nucleic acid sequence-based amplification)  ...  BNCT is applied in clinical trials for the therapy of tumours of the central nervous system as well as head-and neck tumours.  ...  For computer-assisted cytology the ThinPrep Imager has been available since 2003 and the ThinPrep Integrated Imager went on sale in Germany last year.  ... 
doi:10.1007/s00292-011-1423-5 pmid:21528439 fatcat:kyksbxi4k5ch7ff7yne7oiryfu

Abstract Book: ISEV2017

2017 Journal of Extracellular Vesicles  
The content of EVs shed by cancer cells differ from normal cells, but the correlation with tumour characteristics and clinical data remains unknown.  ...  RNAseq data was also obtained from the cell lines and original tumours. Funding: This work is supported by CIHR in partnership with Avon Foundation for Women.  ...  MSC were shown to support regeneration and reparation in various experimental conditions and clinical trials.  ... 
doi:10.1080/20013078.2017.1310414 pmid:29046763 pmcid:PMC5637785 fatcat:ejbhnmhfqbeuronzsj47flas6u

Congress Abstracts

2018 Hämostaseologie  
PAR4 antagonists in clinical settings.  ...  Objectives: Microcirculatory changes contribute to clinical symptoms and disease progression in chronic heart failure (CHF).  ...  The relevance of ADA detection before Nabs development and possible clinical interventions needs to be assessed in clinical trials.  ... 
doi:10.1055/s-0038-1635066 fatcat:fy5yilupqzerfmxf6oq6yv3oxu

Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie e.V

2013 Naunyn-Schmiedeberg's Archives of Pharmacology  
Acknowledgement: This work has been financially supported by DFG and Tubitak with a travel stipend to Aylin Üstündag. [1] Yu, P., Constien, R., Dear, N., Katan, M., Hanke, P., Bunney, T.D., Kunder, S.,  ...  Grosse, J., Wabnitz, P., Meyer, T.P.H., Yasuda, K., Schiemann, M., Schneider-Fresenius, C., Jagla, W., Russ, A., Popp, A., Josephs, M., Marquardt, A., Laufs, J., Schmittwolf, C., Wagner, H., Pfeffer, K., and  ...  trials.  ... 
doi:10.1007/s00210-013-0832-9 pmid:23334796 fatcat:vp56yyyimzfgdgrczauhpodxou

Understanding the influence of health information technology on quality and safety in secondary care

Guy Martin, Sonal Arora, Dominic King, Ara Darzi
2019
Examinations of the impact of organisational digital maturity on clinical outcomes, stakeholder experience and regulatory judgements of quality are presented.  ...  very real and often unexpected risks and challenges that come hand-in-hand with potential opportunities and benefits.  ...  workflow engines/integrated care pathways 59 .  ... 
doi:10.25560/70847 fatcat:bkirt5nc4fb5bjwbqci6x5mchu