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G972R polymorphism of IRS-1 in women with polycystic ovary syndrome

Not Available Not Available
2001 Diabetologia  
is higher in PCOS patients than in normal women.  ...  G972R polymorphism of IRS-1 in women with polycystic ovary syndrome To the Editor: Studies have reported a link between insulin resistance and polycystic ovary syndrome, one of the most common endocrine  ... 
doi:10.1007/s001250170001 pmid:11596679 fatcat:7d4fhzlrzrc3dma5acbsajsjn4

Moterys ir karas ikimoderniosiose baltų visuomenėse | Women and War in Premodern Baltic Societies

Ričardas Dediala, Manvydas Vitkūnas
2021 Acta Historica Universitatis Klaipedensis  
unique cases featuring female activity in military society reveal the importance of their role in tribal decision-making. kEywoRdS: east baltic tribes; female roles; women in war; violence against women  ...  MoTERyS IR kARAS IkIModERNIoSIoSE baltų visuomenėse Ričardas Dediala, manvydas vitkūnas AbSTRACT the role of women in Prehistoric baltic societies has so far received relatively little attention. as for  ... 
doi:10.15181/ahuk.v42i0.2291 fatcat:kp57wwzyjjaxznpztv5ncl7lei

Where Are The Women? A Contemporary Feminist IR Critique Of Security In World Politics

Saima Siddiqui
2020 Pakistan Journal of Gender Studies  
One of the key concerns for this assessment is marginalisation women and gender perspectives in security studies.  ...  The international relations (IR) discourse has been a subject of feminist critique for over two decades.  ...  This concept is influenced with realist theory of IR with is based on the principals of hegemonic masculinity socially constructing certain stereotypical representation on women and men.  ... 
doi:10.46568/pjgs.v7i1.271 fatcat:y7jv6hj5vra5dp3g4zsgyzhlfa

Association of Genetic Polymorphism of Insulin Receptor Substrate 1 (IRS-1) with Polycystic Ovary Syndrome Pathogenicity in Iraqi Women

2021 Medico-Legal Update  
IRS1 is essentially found in the cytoplasm But localization in nucleus may occur in some cell types and under certain stimuli.  ...  Materials and Method: A total of 104 healthy control and 215 Iraqi women have Polycystic ovary syndrome (PCOS) aged 20-40 years who was admitted to conducted a prospective clinical study at kerbala gynecology  ...  In adipocytes of women with PCOS that decrease insulin responsiveness (5) .  ... 
doi:10.37506/mlu.v21i2.2699 fatcat:5fbnw2vf5naqdjbknpbzeznxbq

Health-Related Quality of Life of Young Addict Women in Mashhad, IR Iran

Mohammad Khajedaluee, Reza Assadi, Maliheh Dadgar Moghadam
2013 international journal high risk behaviors & addiction  
Quality of life (QoL) stands for to the general well-being of the populations in the societies.  ...  Objectives: This study attempted to evaluate the QoL of the young addicted women compared to non-addict controls.  ...  Although there is a significant gender difference in drug and alcohol abuse, but now a days alcohol and drug abuse is increasing in women. compared to men, women are less likely to use illegal drugs, but  ... 
doi:10.5812/ijhrba.10296 pmid:24971281 pmcid:PMC4070145 fatcat:g65xlrccengl3m7lmho7bromkq

Prevalence of the insulin receptor substrate-1(IRS-1) Gly972Arg and the insulin receptor substrate-2(IRS-2) Gly1057Asp polymorphisms in PCOS patients and non-diabetic healthy women

Batool Rashidi, Leila Azizy, Farhad Najmeddin, Ebrahim Azizi
2011 Journal of Assisted Reproduction and Genetics  
Objective The aim of our study was to investigate the frequency and compare the prevalence of IRS-1Gly972Arg and IRS-2 Gly1057Asp polymorphisms in PCOS patients and non-diabetic healthy women.  ...  Material(s) and method(s) Forty eight Iranian women diagnosed with PCOS were enrolled in this study. Fifty two nondiabetics, non-PCOS women were enrolled as the control group.  ...  IRS-1 and Gly1057Asp in IRS-2 polymorphisms influence glucose homeostasis in premenopausal women, but are not associated with PCOS [14] .  ... 
doi:10.1007/s10815-011-9693-7 pmid:22205343 pmcid:PMC3270138 fatcat:h4biwrflyzffze2socbcfw4mte

Insulin Receptor Substrate-1 (IRS-1) Gly927Arg: Correlation with Gestational Diabetes Mellitus in Saudi Women

Khalid Khalaf Alharbi, Imran Ali Khan, Zeinab Abotalib, Malak Mohammed Al-Hakeem
2014 BioMed Research International  
The frequency of the rs1801278 polymorphism was significantly higher in women with GDM than in women with non-GDM (for TT + CT versus CC:P=0.02).  ...  The aim of the present study was to scrutinize the relationship between the G972R polymorphism of the insulin receptor substrate-1 (IRS-1) gene with GDM in the Saudi female population.  ...  We examined the IRS-1 G972R polymorphism in 500 Saudi women: 200 GDM cases and 300 non-GDM subjects.  ... 
doi:10.1155/2014/146495 pmid:24695443 pmcid:PMC3948357 fatcat:ghpmsy2spzgsjk4txla5kv3azi

Role of Allelic Variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in Moderate-to-Severe Insulin Resistance of Women With Polycystic Ovary Syndrome

S. A. El Mkadem, C. Lautier, F. Macari, N. Molinari, P. Lefebvre, E. Renard, J. C. Gris, G. Cros, J. P. Daures, J. Bringer, M. F. White, F. Grigorescu
2001 Diabetes  
To assess the role of insulin receptor, insulin receptor substrate (IRS)-1, and IRS-2 genes in insulin resistance, we explored the genomic DNA in women with polycystic ovary syndrome (PCOS) and a variable  ...  HOMA IR was higher in carriers of both IRS variants than in those with IRS-2 mutations only or those with wild-type variants (6.2 ؎ 2.3, 2.8 ؎ 0.5, and 1.8 ؎ 0.2, respectively; P < 0.01), and it was significantly  ...  (IRS-2) variants and their combination in total PCOS subjects, groups A and B, and control women Total PCOS Group Group Control subjects A B women P ( 2 ) n 53 25 28 102 IRS-1 gene Gly972Arg (%) 22.6  ... 
doi:10.2337/diabetes.50.9.2164 pmid:11522686 fatcat:d7qkd3cxwfbmtjq4wrulvvckii

Estimating Rate of Insulin Resistance in Patients with Preeclampsia Using HOMA-IR Index and Comparison with Nonpreeclampsia Pregnant Women

Farideh Rezaei Abhari, Maryam Ghanbari Andarieh, Asadollah Farokhfar, Soleiman Ahmady
2014 BioMed Research International  
Based on the experiments conducted on 675 women who were 20 weeks past their pregnancy, 375 cases with preeclampsia were selected and assigned to the case group. 35 other pregnant women were put in the  ...  Homa-Irand rate of insulin resistance was calculated by HOMA-IR and patients were followed up.  ...  Using HOMA-IR, Sierralaguado et al. identified insulin resistance in women with gestational hypertension in early pregnancy [23] ; however, this study did not address preeclampsia.  ... 
doi:10.1155/2014/140851 pmid:24812607 pmcid:PMC4000925 fatcat:q5zyawrhsfgnvmzvaqjgwppazm

The importance of Organizational Commitment for the Work–family Conflict of Men and Women
Vyrų ir moterų įsipareigojimo organizacijai svarba patiriamam darbo ir šeimos konfliktui

Giedre GENEVICIŪTĖ-JANONIENE, Ruta SKUCAITE
2015 Research of Young Scientists in Psychology  
Tyrimu siekta nustatyti įsipareigojimo organizacijai reikšmę vyrų ir moterų patiriamam darbo ir šeimos konfliktui.  ...  Metodika. 388 vyrai ir 437 moterys užpildė Organizacinio įsipareigojimo klausimyno patikslintą versiją (Meyer, Allen, & Smith, 1993), matuojančią emocinį, normatyvinį ir tęstinį įsipareigojimą, Darbo ir  ...  The results have showed that women experience a stronger time (p < 0.001) and strain (p = 0.004) based work-family conflict than men, whereas there was no difference in three components of organizational  ... 
doi:10.15388/jmpd.2014.3.03 fatcat:nyd6rosry5e73ayiepyx57ptv4

Moterys Lietuvių fronto bičiulių organizacijoje
Women in the friends of the Lithuanian front organization

Ilona Strumickienė
2017 OIKOS lietuvių migracijos ir diasporos studijos  
laisvinimo ir lietuvių tautinės tapatybės išsaugojimo kryptimi.  ...  Straipsnyje pristatomos moterų funkcijos šioje organizacijoje, svarstomos priežastys, lėmusios tai, kad šioje, kaip ir daugelyje kitų lietuvių išeivijos organizacijų, dominavo ir vadovo funkcijas atliko  ...  Gi LFB sąjūdyje susispietę daugelis intelektualiai ir kūrybiškai pajėgių ir išsilavinusių vyrų.  ... 
doi:10.7220/2351-6561.23-24.7 fatcat:u3vlw2sbfzelbdc7kttbe5kkge

IRS-1 gene polymorphism and DNA damage in pregnant women with diabetes or mild gestational hyperglycemia

Rafael B Gelaleti, Débora C Damasceno, Daisy M F Salvadori, João Paulo C Marcondes, Paula H O Lima, Glilciane Morceli, Iracema M P Calderon, Marilza V C Rudge
2015 Diabetology & Metabolic Syndrome  
The aims of this study were to evaluate the presence of the IRS-1 Arg972 polymorphism in pregnant women with diabetes or mild gestational hyperglycemia, and in their newborns.  ...  Conclusion: The polymorphism was more prevalent in newborns of diabetic and MGH women.  ...  Acknowledgements The authors are thankful to the staff of the Laboratory for Experimental Research in Gynecology and Obstetrics and to Talisia  ... 
doi:10.1186/s13098-015-0026-3 pmid:25859280 pmcid:PMC4391297 fatcat:nnmaz4muubccfdyvyzw3p4wm6y

Tapatybės transformacijos naujausioje lietuvių moterų prozoje
Transformations of identity in the newest prose by Lithuanian women

Martyna Kučinskaitė
2019 OIKOS lietuvių migracijos ir diasporos studijos  
Rykštaitės pagrindinė veikėja taip pat nori užmiršti savo šaknis ir susikurti naują, nepriklausomą gyvenimą Londone. Priešingai elgiasi U.  ...  Šių dienų emigracija iš Lietuvos didėja, augantis išvykusiųjų skaičius kelia nerimą Lietuvos vyriausybei ir kitoms institucijoms, o svetur gyvenančiųjų emigracijos patirtys ryškėja naujausioje lietuvių  ...  The article-project "Transformations of Identity in the Newest Prose of Lithuanian Women" (contract No. 09.3.3-LMT-K-712-09-0267) was prepared during July-August in 2018 as a result of winning the Summer  ... 
doi:10.7220/2351-6561.28.7 fatcat:nqqm44ulyzebrjgsxqpwmanxu4

Effects of Line Dance Exercise on HOMA-IR and Energy Metabolic Factors in Postmenopausal Obese Women
라인댄스 운동이 폐경 후 비만여성의 인슐린저항성지수와 에너지대사조절인자에 미치는 영향

Jeong-Ah Lee, Do-Yoen Kim
2012 Journal of the Korea Academia-Industrial cooperation Society  
Abstract The purpose of this study was to analyze the effects of line dance exercise on HOMA-IR and energy metabolic factors in postmenopausal obese women.  ...  And ghrelin, leptin, insulin, and glucose were the energy metabolic factors affecting the HOMA-IR in the line dance group.  ...  )에 의한 선형회귀분석(linear regression analysis)을 실시하였 [표 3] 12주간 라인댄스 운동 후 체조성 및 VFA 변화 [Table 3] Changes in body composition and VFA after 12 weeks line dance exercise 12주간 라인댄스운동 후 HOMA-IR과 에너지대사조절 인자의 회귀분석결과는  ... 
doi:10.5762/kais.2012.13.10.4636 fatcat:hh5ddvkxrrgtpcx4zpwc47rhba

Identification of the Pelvic Organ Prolapse/Incontinence Sexual Questionnaire—IUGA Revised (PISQ-IR) Cutoff Scores for Impaired Sexual Function in Women with Pelvic Floor Disorders

Magdalena Emilia Grzybowska, Konrad Futyma, Dariusz Wydra
2019 Journal of Clinical Medicine  
dysfunction in SA women with PFD, with 90% sensitivity and 71% specificity.  ...  The aim of this cross-sectional study was to determine the cutoff scores for sexual dysfunction in disease-specific Pelvic Organ Prolapse/Incontinence Sexual Questionnaire—IUGA Revised (PISQ-IR) for women  ...  Concluding Message Defining the cutoff score of PISQ-IR in women with PFD is an important step in the development of the questionnaire.  ... 
doi:10.3390/jcm9010013 pmid:31861568 pmcid:PMC7020082 fatcat:m7pr26z7gzaw5gtcfewsigomau
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