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Risk Regulation at Risk: Restoring a Pragmatic Approach by S.A. Shapiro and R. L. Glicksman. Stanford, CA: Stanford University Press, (2003). Reviewed by William S. Bradley

William S. Bradley
2004 Journal of Political Ecology  
doi:10.2458/v11i1.21669 fatcat:rbzsfp3vtbhftnc4a6eh33ck74

Monitoring of the Stanford Linac Microbunches' Position

J.-C. Denard, G. Oxoby, J.-L. Pellegrin, S. Williams
1983 IEEE Transactions on Nuclear Science  
A neu hardware has been developed to measure the trajectory of nlcrobunches along the Stanford Llnac.  ... 
doi:10.1109/tns.1983.4332818 fatcat:gu4r7c33ibcj7iyimjoffrczne

A Comparison of the Grace Arthur, Revised Form II, and the Stanford-Binet, Revised Form L

George Manolakes, William D. Sheldon
1952 Educational and Psychological Measurement  
A COMPARISON OF THE GRACE ARTHUR, REVISED FORM II, AND THE STANFORD-BINET, REVISED FORM L* GEORGE MANOLAKES and WILLIAM D.  ...  The present article presents the results of the Stanford Binet Intelligence Scale, Revised Form L, and the Grace Arthur Performance Scale (Revised Form II).  ... 
doi:10.1177/001316445201200111 fatcat:tjlcjofoybfjjofn4wwgwmftmi

Stanford Seven-Day Physical Activity Recall questionnaire in COPD

Benjamin E. Garfield, Jane L. Canavan, Cayley J. Smith, Karen A. Ingram, Ria P. Fowler, Amy L. Clark, Michael I. Polkey, William D-C. Man
2011 European Respiratory Journal  
The aim of our study was to evaluate the Stanford Seven-Day Physical Activity Recall questionnaire (PAR) against the SenseWear armband (SWA) and compare its validity with three other physical activity  ...  METs correlated significantly with SWA-derived time o3 METs (r50.54, p,0.001) and with SWA-derived PAL (r50.46, p50.002) (fig TABLE 1 1 Patient demographics Sex M/ /F n 18/25 Age yrs 68¡9 FEV1 L?  ...  The Stanford Seven-Day Physical Activity Recall questionnaire (PAR) is interviewer led and is widely used in epidemiological studies [15] .  ... 
doi:10.1183/09031936.00113611 pmid:22183486 fatcat:4phihppstba7fdhecsh6yny4q4

Chromatography.Harold G. Cassidy , Norman Applezweig , Stig Claesson , Victor R. Deitz , Beveridge J. Mair , A. J. P. Martin , Stanford Moore , Robert L. Peck , W. A. Schroeder , Leo Shedlovsky , William H. Stein , Henry C. Thomas , L. Zechmeister

Francis Haxo
1949 The Quarterly review of biology  
Martin, Stanford Moore, Robert L. Peck, W. A. Schroeder, Leo Shedlovsky, William H. Stein, Henry C. Thomas, and L. Zechmeister. New York Academy of Sciences, New York. $2.75 (paper).  ...  L. Chaikoff, Joseph G. Hamilton, Byron E. Hall, Saul Herts, William F. Bale, James J. Nickson, and Farrington Daniels.  ... 
doi:10.1086/396889 fatcat:hi6ugk46erbthjmeyk3onz5jfq

Application of stem cells in bone repair

Elaine Y. L. Waese, Rita R. Kandel, William L. Stanford
2008 Skeletal Radiology  
Bone has the ability to repair minor injuries through remodeling. However, when the host source of osteoprogenitors is compromised at the defect site, one effective treatment may be cell-based therapy, as it replenishes the area of bone loss with cells possessing osteogenic potential. This review is a concise comparison of different types of stem cells that have the potential to be used in tissue-engineered scaffolds for bone repair. The clinical use of mesenchymal stem or stromal cells
more » ... from the bone marrow for treating various diseases has been well documented. However, the scarcity of these cells prompts the search for alternative sources of multipotential cells such as amniotic fluid stem cells and umbilical cord perivascular cells. Embryonic stem cells are another controversial source of cells with osteogenic potential. These cells have the ability to differentiate into all cell types of the adult body. Issues such as the use of human embryos and the risk of contamination from animal-derived culture components continue to prevent the therapeutic use of ESCs. As a result, abundant research has been carried out to design defined culture conditions for culturing ESCs, and alternative strategies such as the generation of induced pluripotent stem cells are being developed to eliminate the need for using embryos for cell derivation. In addition to the cell source, the ability to control stem cell differentiation into functional bone and the choice of biomaterial are also paramount objectives that are being examined in research and clinical trials.
doi:10.1007/s00256-007-0438-8 pmid:18193216 fatcat:5zkzknofzvh2lpyegvf6ywwcl4

Application of stem cells in bone repair

Elaine Y. L. Waese, Rita A. Kandel, William L. Stanford
2008 Skeletal Radiology  
Bone has the ability to repair minor injuries through remodeling. However, when the host source of osteoprogenitors is compromised at the defect site, one effective treatment may be cell-based therapy, as it replenishes the area of bone loss with cells possessing osteogenic potential. This review is a concise comparison of different types of stem cells that have the potential to be used in tissue-engineered scaffolds for bone repair. The clinical use of mesenchymal stem or stromal cells
more » ... from the bone marrow for treating various diseases has been well documented. However, the scarcity of these cells prompts the search for alternative sources of multipotential cells such as amniotic fluid stem cells and umbilical cord perivascular cells. Embryonic stem cells are another controversial source of cells with osteogenic potential. These cells have the ability to differentiate into all cell types of the adult body. Issues such as the use of human embryos and the risk of contamination from animal-derived culture components continue to prevent the therapeutic use of ESCs. As a result, abundant research has been carried out to design defined culture conditions for culturing ESCs, and alternative strategies such as the generation of induced pluripotent stem cells are being developed to eliminate the need for using embryos for cell derivation. In addition to the cell source, the ability to control stem cell differentiation into functional bone and the choice of biomaterial are also paramount objectives that are being examined in research and clinical trials.
doi:10.1007/s00256-008-0476-x fatcat:ch4hvwvlqjdono6g5mnsfxtb2m

MKRN1: Uncovering function by an unbiased systems approach

Richard L. Carpenedo, Paul A. Cassar, William L. Stanford
2016 Cell Cycle  
CONTACT Richard L. Carpenedo rcarpenedo@ohri.ca; William L. Stanford wstanford@ohri.ca The Ottawa Hospital Research Institute, 501 Smyth Road, Box 511, Ottawa, Ontario K1H 8L6 Canada.  ... 
doi:10.1080/15384101.2015.1124698 pmid:26651844 pmcid:PMC4943698 fatcat:fw74lvtqmrfmtcc5zrijn7ixla

Baroclinic wave variations observed in MLS upper tropospheric water vapor

Elizabeth M. Stone, William J. Randel, John L. Stanford, William G. Read, Joe W. Waters
1996 Geophysical Research Letters  
;, 3'-::';-, ':7 •'•-'l:; z' 4Time versus longitude diagram of zonal waves 4-6 MLS water vapor at 44øS and 215 hPa.  ...  Observed Medium Scale Wave Features Figure l a shows a synoptic map of the MLS upper tropospheric water vapor data at 215 hPa on 20 January 1992.  ... 
doi:10.1029/96gl02576 fatcat:zuh7ar6qunfqbhqbdkfg4re6jq

Inhibition of Tgf-β Signaling Improves Mouse Fibroblast Reprogramming

Knut Woltjen, William L. Stanford
2009 Cell Stem Cell  
Previously, it was observed that the small molecules BIX and BayK, HMTase and L-type calcium channel inhibitors, respectively, may also be used to replace Sox2 in mouse fibroblast reprogramming (Shi et  ...  Ichida et al. suggest this effect is not mediated through direct destabilization of the MEF transcriptional program but, rather, through activation of L-Myc, which can replace c-Myc in reprogramming of  ... 
doi:10.1016/j.stem.2009.10.007 pmid:19896434 fatcat:bnr4k2swg5bdlkyi2moh36iapy

Thrombin mediated migration of osteogenic cells

Jeffrey M. Karp, Tetsuya S. Tanaka, Ron Zohar, Jaro Sodek, Molly S. Shoichet, John E. Davies, William L. Stanford
2005 Bone  
After 48 h (K,L) Fig. 6 . 6 Combined cell migration and bone nodule assay.  ...  Penicillin G, amphotericin, dexamethasone, l-ascorbic acid, sodium-hglycerophosphate, bovine serum albumin (BSA), PDGF-BB, and mitomycin-C were obtained from Sigma.  ... 
doi:10.1016/j.bone.2005.04.022 pmid:15964256 fatcat:b7p3zj5s2fbovf3lc7uttcnu4i

22 RISK FACTORS FOR HYPERTENSION IN COLLEGE STUDENTS

Robert L Williams, Abdollah Iravani, George A Richard, Manop Luengnaruemitchai, Stanford T Shulman
1978 Pediatric Research  
e l e a r n i n g .  ...  NYC A m o s t disturbing a s p e c t of Lesch-Nyhan d i s e a s e IS self-mutit e w a s 3.4/min confirming under c o n t r o l l e d c o n d l t l o n s a d e f e c t i n p a s s i v e a v o i d a n c  ... 
doi:10.1203/00006450-197804001-00027 fatcat:b4ey3dl4ijfzbkv5x2jbw2syse

Positive Surgical Margins at Radical Prostatectomy Predict Prostate Cancer Specific Mortality

Jonathan L. Wright, Bruce L. Dalkin, Lawrence D. True, William J. Ellis, Janet L. Stanford, Paul H. Lange, Daniel W. Lin
2010 Journal of Urology  
Purpose-Positive surgical margins (PSM) in men undergoing radical prostatectomy (RP) for prostate cancer (PCa) are associated with an increased risk of biochemical recurrence. Little data have evaluated the role of PSM in PCa-specific mortality (PCSM). Using a large, populationbased national cancer registry, we evaluate the risk of PCSM associated with margin status. Methods-The SEER cancer registry data for patients diagnosed in 1998-2006 were used to identify men undergoing RP for PCa. Margin
more » ... status, pathologic stage, Gleason grade and postoperative radiation therapy were recorded along with demographic data. Multivariate Cox regression analysis was used to estimate the risk of PCSM associated with PSMs. Results-A total of 65,633 patients comprised the cohort in which 291 (0.44%) PCa-specific deaths occurred over an average follow-up of 50 months. PSMs were reported in 21.2% and were more common in pT3a than pT2 tumors (44% vs. 18%, p<0.001) and higher grade tumors (28% vs. 18%, p<0.001). The 7-year disease-specific survival rates for those at highest risk of PCSM (higher grade pT3a) were 97.3% for cases with negative surgical margins and 92.4% for those with PSMs. PSMs were associated with a 2.9-fold increased risk of PCSM (HR 2.55, 95% CI 2.02 -3.21). PSM remained an independent predictor of PCSM in the multivariate analysis (HR 1.70, 95% CI 1.32 -2.18). Conclusion-These data demonstrate the independent role of positive surgical margin in PCSM. These finding support the importance of optimizing surgical technique to achieve a sound oncologic surgical outcome with negative surgical margins when possible.
doi:10.1016/j.juro.2010.02.017 pmid:20399459 pmcid:PMC2903223 fatcat:6y726bnp5zdg5lsa2c3lewqxhy

Promoting culturally targeted chronic disease prevention research through an adapted participatory research approach: The Qassim-Stanford Universities project

Sandra J Winter, Abby C King, Randall S Stafford, Marilyn A Winkleby, William L Haskell, John W Farquhar
2011 Translational Behavioral Medicine  
the chronic disease prevention and health promotion (CDPHP) knowledge available from other nations, researchers at a newly established University in the Qassim Province of the KSA have partnered with Stanford  ...  , obesity (having a BMI greater than or equal to 30 kg/m 2 ), and diabetes (defined using the 1997 American Diabetes Association guidelines of fasting plasma glucose equal to or greater than 7.0 mmol/l  ...  [40] 54 54.9 53.2 53.4 55.3 Hypertriglycemia (total triglycerides ≥1.69 mmol/l) [40] 40.3 47.6 33.7 - - Physical inactivity [41] 96.1 93.9 98.1 - - a Sample sizes vary slightly by  ... 
doi:10.1007/s13142-011-0033-3 pmid:24073051 pmcid:PMC3717657 fatcat:dmlsdicl55agzpxd4upteczdaq

PCL2 modulates gene regulatory networks controlling self-renewal and commitment in embryonic stem cells

Emily Walker, Janet L. Manias, Wing Y. Chang, William L. Stanford
2011 Cell Cycle  
R ecent reports have better elucidated the components of the Polycomb Repressive Complex 2 (PRC2) and its functional role in embryonic stem cells (ESCs) and their differentiated derivatives. The depletion of a newly described mammalian PRC2 associated protein, PCL2, leads to an increase in ESC selfrenewal and a delay in differentiation, a phenotype similar to knockouts of the core PRC2 members. Genomic and cell biology data suggest that PCL2 is important in cell fate decisions and may play a
more » ... e in recruitment of PRC2 to target genes and histone methylation. Importantly, depletion of PCL2 in ESCs leads to a decrease in 3meH3K27 at the proximal promoter regions of pluripotency transcription factors Tbx3, Klf4, Foxd3 and a concomitant increase in gene expression. These proteins subsequently activate expression of Oct4, Nanog and Sox2 through a feed-forward gene regulatory circuit, altering the core pluripotency network and driving cell fate decisions towards self-renewal. We propose a model whereby alteration of the epigenetic state of Tbx3, Klf4 and Foxd3 results in the enforced expression of the pluripotency network, preventing differentiation.
doi:10.4161/cc.10.1.14389 pmid:21193838 pmcid:PMC3048073 fatcat:nbf2wjgwgvfapden45p2m76wzi
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