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Occupational Characteristics of Leading Canadian Executives
1973
Relations Industrielles - Industrial Relations
DALY, William G., Instructor, Institute of Technology, Northern Alberta. ...
Moore and William G. Daly
ff. 12 Laurent BÉLANGER, Occupational Mobility of French and English Canadian Business Leaders in the Province of Québec (Unpublished Ph.D. dissertation) E. ...
doi:10.7202/028368ar
fatcat:yw2b2ivde5eabkaa3kw7butfra
Non-invasive detection of hypoglycaemia using a novel, fully biocompatible and patient friendly alarm system
2000
BMJ (Clinical Research Edition)
professor of medicine
Department of
Medicine, Wansbeck
General Hospital,
Ashington
NE63 9JJ
Mark Daly
specialist registrar in
endocrinology and
diabetes
Correspondence to:
G Williams
garethw ...
Hospital
Aintree, Liverpool
L9 7AL
Mimi Chen
preregistration house
officer
Natt
junior research
assistant
Susie
intermediate research
assistant
Candy
senior research
assistant
Gareth Williams ...
doi:10.1136/bmj.321.7276.1565
pmid:11124176
pmcid:PMC27564
fatcat:d5zcb5efhbb2hitjy5uevq3oba
Genetic variation in surfactant protein-A2 alters responses to ozone
2021
PLoS ONE
Cyphert-Daly, Robert M. Tighe, Loretta G. Que, Julie G. Ledford. Supervision: Julie G. Ledford. Validation: Julie G. Ledford. Visualization: William P. Pederson, Julie G. Ledford. ...
nystatin (Sigma), 50 μg/ml gentamicin. ...
doi:10.1371/journal.pone.0247504
pmid:33617569
pmcid:PMC7899376
fatcat:zz7z4ecjr5darnmk7355pcke2e
Nonlinear Analysis of Aortic Flow in Living Dogs
1973
Circulation Research
G. Johnson for technical assistance. ...
F: Pressure gradient wave, g: Circumferential dis;ention wave, h: Velocity-gradient wave at the wall, i: Discharge wave. See text for abbreviations. ...
doi:10.1161/01.res.33.2.198
pmid:4727371
fatcat:mytnaxr6bngitpwtwmc7kqzvf4
Nomenclature and classification of purinoceptors
1994
Pharmacological Reviews
A., BURNSTOCK, G., AND WEBB, T. E.: G-protein coupled receptors B. P., WILLIAMS, C. A., AND CEELEN, P. W.: ATP-activated C. D., AND TSIEN, R. W.: A novel receptor-operated BERNE, R. ...
G-protein-coupled#
G-protein-coupled
Nonselective
pore
G-protein
coupled? ...
.: Receptor-to-effector signaling through G proteins: roles for '3/ 7dimers as well as a subunits. Cell 71: 1069-1072, 1992. ...
pmid:7938164
pmcid:PMC4976594
fatcat:omj6gy4xr5fcnhxo7criywu5jm
Exome Sequencing Identifies a DominantTNNT3Mutation in a Large Family with Distal Arthrogryposis
2014
Molecular Syndromology
Protein effect
SDK1
c.5540G>A
p.Arg1847Gln
-
SIFT = tolerated (0.82)/PolyPhen = benign (0.078)
NOD1
c.676G>A
p.Ala226Thr
-
SIFT = tolerated (0.76)/PolyPhen = benign (0.008)
C8orf40
c.125A>G ...
p.Tyr42Cys
-
SIFT = deleterious (0)/PolyPhen = probably damaging (0.997)
OR52N4
c.323C>G
p.Thr108Ser
-
SIFT = tolerated (0.54)/PolyPhen = benign (0.014)
DNHD1
c.100C>T
p.Gln34Ter
-
not predictable ...
doi:10.1159/000365057
pmid:25337069
pmcid:PMC4188168
fatcat:dc6mo3vlbfcrtlphxprtfqkgky
Möbius: An Extensible Tool for Performance and Dependability Modeling
[chapter]
2000
Lecture Notes in Computer Science
Acknowledgments We would like to acknowledge the work done by former members of the Möbius group: G. P. Kavanaugh, J. M. Sowder, and A. L. Williamson. ...
Evc 1999, David Daly, Daniel D. Deavours, Jay M. Doyle, Aaron J. Stillman, Patrick G. Webster
Figure 1 . 1 Möbius Architecture. ...
doi:10.1007/3-540-46429-8_25
fatcat:y7retbl2w5cfxdszrtxujgymny
The functional neuroanatomy of social behaviour
2000
Brain
Although high-functioning individuals with autistic disorder (i.e. autism and Asperger syndrome) are of normal intelligence, they have life-long abnormalities in social communication and emotional behaviour. However, the biological basis of social difficulties in autism is poorly understood. Facial expressions help shape behaviour, and we investigated if high-functioning people with autistic disorder show neurobiological differences from controls when processing emotional facial expressions. We
doi:10.1093/brain/123.11.2203
pmid:11050021
fatcat:cqnf4mh7fjc4tf656jk4kdmgta
more »
... used functional MRI to investigate brain activity in nine adults with autistic disorder (mean age ⍨ standard deviation 37 ⍨ 7 years; IQ 102 ⍨ 15) and nine controls (27 ⍨ 7 years; IQ 116 ⍨ 10) when explicitly (consciously) and implicitly (unconsciously) processing Abbreviations: BOLD ϭ blood oxygenation level-dependent; fMRI ϭ functional MRI; FPQ ϭ fundamental power quotient; ICD ϭ International Classification of Disease; WAIS-R ϭ Wechsler Adult Intelligence Scale-Revised
Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls
2001
Nature Genetics
Incidence, Event Rates, and Early Outcome of Stroke in Dublin, Ireland: The North Dublin Population Stroke Study
2012
Stroke
and Purpose-The World Health Organization has emphasized the importance of international populationbased data for unbiased surveillance of stroke incidence and outcome. To date, few such studies have been conducted using recommended gold-standard ascertainment methods. We conducted a large, population-based stroke study in Dublin, Ireland. Methods-Using gold-standard ascertainment methods, individuals with stroke and transient ischemic attack occurring over a 12-month period (December 1,
doi:10.1161/strokeaha.111.645721
pmid:22693134
fatcat:i7hxu5lt4rfktj6x3hgwujbqiu
more »
... vember 30, 2006 in North Dublin were identified. Disability was assessed using the modified Rankin score and stroke severity (Ͻ72 hours) by the National Institutes of Health Stroke Scale. Stroke-related deaths were confirmed by review of medical files, death certificates, pathology, and coroner's records. Crude and standardized (to European and World Health Organization standard populations) rates of incidence, risk factors, severity, and early outcome (mortality, case-fatality, disability) were calculated, assuming a Poisson distribution for the number of events. Results-Seven hundred one patients with new stroke or transient ischemic attack were ascertained (485 first-ever stroke patients, 83 recurrent stroke patients, 133 first-ever transient ischemic attack patients). Crude frequency rates (all rates per 1000 person-years) were: 1.65 (95% CI, 1.5-1.79; first-ever stroke), 0.28 (95% CI, 0.22-0.35; recurrent stroke), and 0.45 (95% CI, 0.37-0.53; first-ever transient ischemic attack). Age-adjusted stroke rates were higher than those in 9 other recent population-based samples from high-income countries. High rates of subtype-specific risk factors were observed (atrial fibrillation, 31.3% and smoking, 29.1% in ischemic stroke; warfarin use, 21.2% in primary intracerebral hemorrhage; smoking, 53.9% in subarachnoid hemorrhage; PϽ0.01 for all compared with other subtypes). Compared with recent studies, 28-day case-fatality rates for primary intracerebral hemorrhage (41%; 95% CI, 29.2%-54.1%) and subarachnoid hemorrhage (46%; 95% CI, 28.8%-64.5%) were greater in Dublin. Conclusions-Using gold-standard methods for case ascertainment, we found high incidence rates of stroke in Dublin compared with those in similar high-income countries; this is likely explained in part by high rates of subtype-specific risk factors.
Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion
2017
Nature Biomedical Engineering
Tissue-culture polystyrene plates were coated using Matrigel (Corning, NY) at a density of 0.0087 µg/cm 2 . ...
All medium was supplemented with 100 U/mL Penicillin/100 µg/mL Streptomycin (Thermo Fisher Scientific, Inc., Carlsbad, CA). ...
doi:10.1038/s41551-017-0096
pmid:29104816
pmcid:PMC5667681
fatcat:tas24if6krezjcu3owm4hqq34y
Cardiotocography versus intermittent auscultation of fetal heart on admission to labour ward for assessment of fetal wellbeing
2017
The Cochrane library
A C K N O W L E D G E M E N T S Our thanks to Mr Lawrence Impey who provided additional data for Impey 2003, to Dr Helen Cheyne who provided additional data for Cheyne 2003 and to Dr Fiona Williams who ...
P L A I N L A N G U A G E S U M M A R Y
Comparing electronic monitoring of the baby's heartbeat on a woman's admission in labour using cardiotocography (CTG) with intermittent monitoring What is the ...
doi:10.1002/14651858.cd005122.pub5
pmid:28125772
pmcid:PMC6464914
fatcat:j5gggrfftvbktlobtp2pjq3tc4
White-matter relaxation time and myelin water fraction differences in young adults with autism
2014
Psychological Medicine
Background. Increasing evidence suggests that autism is associated with abnormal white-matter (WM) anatomy and impaired brain 'connectivity'. While myelin plays a critical role in synchronized brain communication, its aetiological role in autistic symptoms has only been indirectly addressed by WM volumetric, relaxometry and diffusion tensor imaging studies. A potentially more specific measure of myelin content, termed myelin water fraction (MWF), could provide improved sensitivity to myelin
doi:10.1017/s0033291714001858
pmid:25111948
fatcat:2s52qhl4zfe5lecs6l7cat7zbe
more »
... ration in autism. Method. We performed a cross-sectional imaging study that compared 14 individuals with autism and 14 age-and IQ-matched controls. T 1 relaxation times (T 1 ), T 2 relaxation times (T 2 ) and MWF values were compared between autistic subjects, diagnosed using the Autism Diagnostic Interview -Revised (ADI-R), with current symptoms assessed using the Autism Diagnostic Observation Schedule (ADOS) and typical healthy controls. Correlations between T 1 , T 2 and MWF values with clinical measures [ADI-R, ADOS, and the Autism Quotient (AQ)] were also assessed. Results. Individuals with autism showed widespread WM T 1 and MWF differences compared to typical controls. Within autistic individuals, worse current social interaction skill as measured by the ADOS was related to reduced MWF although not T 1 . No significant differences or correlations with symptoms were observed with respect to T 2 . Conclusions. Autistic individuals have significantly lower global MWF and higher T 1 , suggesting widespread alteration in tissue microstructure and biochemistry. Areas of difference, including thalamic projections, cerebellum and cingulum, have previously been implicated in the disorder; however, this is the first study to specifically indicate myelin alteration in these regions.
Mutations in LZTR1 add to the complex heterogeneity of schwannomatosis
2014
Neurology
William G. ...
Simon G. Williams: analysis or interpretation of data, accepts responsibility for conduct of research and will give final approval. Sanjeev S. ...
doi:10.1212/wnl.0000000000001129
pmid:25480913
pmcid:PMC4336087
fatcat:q5dz2qnxpbcvvpjjr3xkkvrdqm
Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels
2018
Advanced Healthcare Materials
vascular endothelial growth factor A (VEGF-A; 50 μg L −1 ). ...
After culturing the cells for 2 d in E8BAC medium (E8 medium with Activin A (25 μg L −1 ), BMP4 (5 μg L −1 ), and CHIR 99021 (1 × 10 −6 m)), the cells were cultured in E7Vi medium (E8 medium with VEGF-A ...
doi:10.1002/adhm.201801186
pmid:30565891
pmcid:PMC6601624
fatcat:x5zy4atb5zh2do2etdwfmldzlq
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