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Neural Profile of Callous Traits in Children: A Population-Based Neuroimaging Study

Koen Bolhuis, Essi Viding, Ryan L. Muetzel, Hanan El Marroun, Desana Kocevska, Tonya White, Henning Tiemeier, Charlotte A.M. Cecil
2019 Biological Psychiatry  
We characterized gray and white matter brain correlates of callous traits in over 2000 children from the general population.  ...  ., lack of remorse and shallow affect, are a key risk marker for antisocial behavior.  ...  ACKNOWLEDGMENTS AND DISCLOSURES We thank all children and parents, general practitioners, hospitals, midwives, and pharmacies involved in the Generation R Study.  ... 
doi:10.1016/j.biopsych.2018.10.015 pmid:30554676 fatcat:rmcq6t3ssnegpm5or4ojei3cce

Randomized controlled trial of a mindfulness‐based intervention in adolescents from the general population: The Mindfulteen neuroimaging study protocol

Camille Piguet, Paul Klauser, Zeynep Celen, Ryan Murray, Mariana Magnus Smith, Arnaud Merglen
2021 Early Intervention in Psychiatry  
To the best of our knowledge, this is the first randomized controlled trail examining the effect of a mindfulness-based intervention in young adolescents from the general population based on the measurement  ...  The Mindfulteen Study is a 3-year longitudinal cohort with a nested randomized controlled trial examining the effectiveness of mindfulness-based interventions for adolescents.  ...  ACKNOWLEDGEMENTS This study is supported by a fund granted by the Leenaards Founda-  ... 
doi:10.1111/eip.13235 pmid:34734463 fatcat:ywpm6bkdxfctlchecdus2xly5e

Cognitive Function Estimation in Children with Tuberous Sclerosis

L Troitskaya, N Malahova
2018 KnE Life Sciences  
Tuberous sclerosis (TSC) is a genetic disease characterized by cerebral structural abnormalities (such as cortical tubers, subependymal nodes and abnormal cerebral white matter) which are detected by means  ...  According to comparison between research findings and clinical course data, severity of cognitive disorders substantially depends on epilepsy onset age because early onset results in more severe developmental  ...  Age group-based characterization of TSC children considering severity of the disease and mode of study is presented in Tables 1-2.  ... 
doi:10.18502/kls.v4i8.3345 fatcat:4lxkerzqn5cvxbmd73tpecuzbm

Neurocognitive deficits and neuroimaging abnormalities are prevalent in children with lupus: clinical and research experiences at a US pediatric institution

E. Muscal, DR Bloom, JV Hunter, BL Myones
2009 Lupus  
White matter hyperintensities were observed in retrospective and prospective cohort MRIs (36.6% and 46.7% respectively).  ...  Data from 15 children enrolled in a prospective structure-function association study was also analyzed.  ...  effects on gray and white matter structures may contribute to cognitive domain deficits observed in children and adults with SLE  ... 
doi:10.1177/0961203309352092 pmid:20026519 pmcid:PMC2980849 fatcat:essgibnvnvdpnbhk3ywdzyvs6a

Relationship between age and white matter integrity in children with phenylketonuria

Erika Wesonga, Joshua S. Shimony, Jerrel Rutlin, Dorothy K. Grange, Desiree A. White
2016 Molecular Genetics and Metabolism Reports  
However, little research has been conducted to investigate the relationship between age and white matter integrity in this population.  ...  The present study examined group differences in the relationship between age and MD across a range of brain regions in 31 children with early- and continuously-treated PKU and 51 healthy control children  ...  We would like to thank the physicians, faculty, and staff of WU and OHSU for their contributions to the study, as well as Suzin Blankenship and Laurie Sprietsma who assisted in study coordination and data  ... 
doi:10.1016/j.ymgmr.2016.03.003 pmid:27114916 pmcid:PMC4832081 fatcat:blydp26bknajlkyvlzrcqonhju

An Updated Systematic Review of Neuroimaging Studies of Children and Adolescents with Perinatally Acquired HIV

Kayla A. Musielak, Jodene Goldenring Fine
2015 Journal of Pediatric Neuropsychology  
Imaging was focused primarily on white matter, and white matter issues such as lesions, poor tract integrity, and reduced volume were found in samples of children and adolescents of various age ranges.  ...  Two studies compared the cognitive functioning of children with HIV to controls, and both found that children with HIV perform more poorly than their non-infected peers on various cognitive tasks.  ...  Compliance with Ethical Standards Ethics Statement No animal or human studies were carried out by the authors for this article. Funding No funding was secured for this study.  ... 
doi:10.1007/s40817-015-0009-1 fatcat:42o6ci46y5evpaaibx3x7msfr4

Brain abnormalities in children and adolescents with chronic kidney disease

Mina Matsuda-Abedini, Kevin Fitzpatrick, Waverly R Harrell, Debbie S Gipson, Stephen R Hooper, Aysenil Belger, Ken Poskitt, Steven P Miller, Bruce H Bjornson
2018 Pediatric Research  
RESULTS: Focal and multifocal white matter injury was seen on brain MRI in 6 children with CKD (21%).  ...  The spectrum of brain injury and microstructural white matter abnormalities in children with CKD is largely unknown. METHODS: Cross sectional study at two North American pediatric hospitals.  ...  Given the potential vascular etiology to the cognitive impairments in this population, these findings and those from our study, support the need for future studies to examine the link between white matter  ... 
doi:10.1038/s41390-018-0037-5 pmid:29967532 fatcat:4e7umtdvzfdyri3m34ih4jacyy

Thalamocortical Connectivity Predicts Cognition in Children Born Preterm

Gareth Ball, Libuse Pazderova, Andrew Chew, Nora Tusor, Nazakat Merchant, Tomoki Arichi, Joanna M. Allsop, Frances M. Cowan, A. David Edwards, Serena J. Counsell
2015 Cerebral Cortex  
The aim of this study was to test the hypothesis: thalamocortical connectivity in the preterm brain at term-equivalent is correlated with cognitive performance in early childhood.  ...  The inclusion of GA at birth and parental socioeconomic group in the model explained 30% of the variance in subsequent cognitive performance.  ...  the children are at school age.  ... 
doi:10.1093/cercor/bhu331 pmid:25596587 pmcid:PMC4816783 fatcat:vzwzcudefratbpzbdj3yyrpv3y

Cognitive Functioning in Patients with Pediatric-Onset Multiple Sclerosis, an Updated Review and Future Focus

Joy B. Parrish, Emily Fields
2019 Children  
This paper hopes to review findings associated with cognitive and psychosocial functioning in patients with POMS, as well as explore more recent advances in the field and how they relate to cognitive and  ...  We also discuss the ongoing need for future studies with a focus on better understanding deficits and disease correlates, but also preventative measures and potential rehabilitation.  ...  Nevertheless, findings suggesting white matter integrity and its importance in cognitive ability have also been demonstrated [85, 86] .  ... 
doi:10.3390/children6020021 pmid:30720736 pmcid:PMC6406784 fatcat:adtxxbqxhrfibo44ok72feq4kq

Neuroimaging at Term Equivalent Age: Is There Value for the Preterm Infant? A Narrative Summary

Rudaina Banihani, Judy Seesahai, Elizabeth Asztalos, Paige Terrien Church
2021 Children  
Advances in neuroimaging of the preterm infant have enhanced the ability to detect brain injury. This added information has been a blessing and a curse.  ...  This narrative summary will review the history and current state of brain imaging, focusing on magnetic resonance imaging in the preterm population and the current state of the evidence for how these patterns  ...  Term age equivalent MRI alone poorly predicted cognitive function for the individual patients at school age or later in life [97, 126] .  ... 
doi:10.3390/children8030227 pmid:33809745 pmcid:PMC8002329 fatcat:sakdj7ywrfbnhj7wotiuzytx2q

Altered microstructural connectivity of the arcuate fasciculus is related to language disability in children with autism spectrum disorder

Mika Kimura, Ryuzo Hanaie, Ikuko Mohri, Kuriko Kagitani-Shimono, Masaya Tachibana, Junko Matsuzaki, Norihiko Fujita, Yoshiyuki Watanabe, Masako Taniike
2013 Journal of brain science  
Cognitive functions correlate with white matter architecture in a normal pediatric population: a diffusion tensor MRI study.  ...  Altered white matter integrity and development in children with autism: a combined voxel-based morphometry and diffusion imaging study, Brain Res Bull. 201ti84(2):189-95. 27,Boddaert  ... 
doi:10.20821/jbs.42.0_21 fatcat:klrdcqypkzhupb5iqcauuzajoa

Cognitive deficits in adults with obstructive sleep apnea compared to children and adolescents

Krzysztof Krysta, Agnieszka Bratek, Karolina Zawada, Radosław Stepańczak
2016 Journal of neural transmission  
In this review, we analyze the most affected cognitive domains in adults and children/adolescents with OSA, as evaluated by neuropsychological and neuroimaging studies.  ...  As OSA can present in all age groups, these associated cognitive deficits have been observed in adults, as well as in children and adolescents.  ...  Some unique cognitive deficits in school-aged children with OSA have been described compared with the adult population.  ... 
doi:10.1007/s00702-015-1501-6 pmid:26729362 pmcid:PMC5281652 fatcat:ebqpdwcj4jeqfj7jp4k72frl6i

Developmental brain trajectories in children with ADHD and controls: a longitudinal neuroimaging study

Timothy J. Silk, Sila Genc, Vicki Anderson, Daryl Efron, Philip Hazell, Jan M. Nicholson, Michael Kean, Charles B. Malpas, Emma Sciberras
2016 BMC Psychiatry  
Methods/Design: NICAP is a multimodal neuroimaging study in a community-based cohort of children with and without ADHD.  ...  Approximately 100 children with ADHD and 100 typically developing controls will be scanned at a mean age of 10 years (range; 9-11years) and will be re-scanned at two 18-month intervals (ages 11.5 and 13  ...  Acknowledgements We would like to thank all of the many families and schools for their participation in this study.  ... 
doi:10.1186/s12888-016-0770-4 pmid:26969310 pmcid:PMC4787204 fatcat:mbwamk4mlngqtnyb32aytcvk2i

White matter microstructure is associated with cognitive control in children

Laura Chaddock-Heyman, Kirk I. Erickson, Michelle W. Voss, John P. Powers, Anya M. Knecht, Matthew B. Pontifex, Eric S. Drollette, R. Davis Moore, Lauren B. Raine, Mark R. Scudder, Charles H. Hillman, Arthur F. Kramer
2013 Biological Psychology  
We examined the relationship between white matter microstructure and cognitive control in 61 children aged 7-9 years using diffusion tensor imaging (DTI).  ...  Fiber tracts in a frontal-parietal-striatal-motor circuit seem to play a role in cognitive control in children.  ...  This work was supported by a grant (HD055352) from the National Institute of Child Health and Human Development to Dr. Charles Hillman.  ... 
doi:10.1016/j.biopsycho.2013.05.008 pmid:23714226 pmcid:PMC3742734 fatcat:cdc2mk47oneqnggulikg4kgn2u

Concussion in Children and Adolescents

Gerald H. Clayton, Michael W. Kirkwood, Scott R. Laker, Pamela E. Wilson
2013 Current Physical Medicine and Rehabilitation Reports  
Pediatric concussion is a growing concern as children across the country become more involved in sports and are leading more active lifestyles.  ...  as well as new approaches to modeling recovery based on biochemical and neuroimaging biomarkers.  ...  Children who had intracranial abnormalities performed worse in multiple cognitive and academic domains when compared with those who had normal CT findings or only a linear skull fracture.  ... 
doi:10.1007/s40141-013-0008-z fatcat:ilgkuhawh5abvf6irrl4eh5yna
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