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Third Theranostics World Congress on Gallium-68 and PRRT: Abstracts

R. P. Baum, R. L. Wahl
2015 Journal of Nuclear Medicine  
detectable in 3/6 patients, and bone lesions were detectable in 1/2 patients.  ...  At least one known lesion was visible in the 90 Y PET images in 17/18 patients (94%). Sensitivity was highest for detection of disease in the pancreas (11/11 lesions detected).  ...  Outside of the liver, all lesions visualized on CT were characterized on whole-body MRI. Image quality between PET/MRI and PET/CT for the whole-body acquisition was equivalent.  ... 
doi:10.2967/jnm565abs pmid:25934686 fatcat:qqgidinlpjb7femnpuwn7yqzwa

Recent developments on the application of molecular probes in multiple myeloma: Beyond [18F]FDG

Shaojuan Zhang, Jingjie Shang, Weijian Ye, Tianming Zhao, Hao Xu, Hui Zeng, Lu Wang
2022 Frontiers in Bioengineering and Biotechnology  
Multiple myeloma (MM) is a neoplastic plasma cell proliferative disorder characterized by various osteolytic bone destruction as a radiological morphological marker.  ...  A summary overview of molecular functional imaging in MM is provided, and commonly used radiotracers are characterized.  ...  Currently, modern recommended imaging technologies include whole-body low-dose computed tomography (WBLWCT), positron emission tomography/computed tomography (PET/ CT), or whole-body magnetic resonance  ... 
doi:10.3389/fbioe.2022.920882 pmid:36091426 pmcid:PMC9459033 fatcat:ct7z3fdgxvce3ihcz27dsuloqe

Automated Whole-Body Bone Lesion Detection for Multiple Myeloma on 68Ga-Pentixafor PET/CT Imaging Using Deep Learning Methods

Lina Xu, Giles Tetteh, Jana Lipkova, Yu Zhao, Hongwei Li, Patrick Christ, Marie Piraud, Andreas Buck, Kuangyu Shi, Bjoern H. Menze
2018 Contrast Media & Molecular Imaging  
The identification of bone lesions is crucial in the diagnostic assessment of multiple myeloma (MM). 68Ga-Pentixafor PET/CT can capture the abnormal molecular expression of CXCR-4 in addition to anatomical  ...  Then the proposed methods were evaluated on real 68Ga-Pentixafor PET/CT scans of MM patients.  ...  Conclusion This study proposed the first computer-aided MM bone lesion detection approach on whole-body 68 Ga-Pentixafor PET/CT imaging.  ... 
doi:10.1155/2018/2391925 pmid:29531504 pmcid:PMC5817261 fatcat:iq2cfq63szdebiay7gwi7uskli

Machine Learning and Deep Learning Applications in Multiple Myeloma Diagnosis, Prognosis, and Treatment Selection

Alessandro Allegra, Alessandro Tonacci, Raffaele Sciaccotta, Sara Genovese, Caterina Musolino, Giovanni Pioggia, Sebastiano Gangemi
2022 Cancers  
Multiple myeloma is one of the most common haematological malignancies in the world, and among them, it is one of the most difficult ones to cure due to the high occurrence of relapse and chemoresistance  ...  Machine learning- and deep learning-based studies are expected to be among the future strategies to challenge this negative-prognosis tumour via the detection of new markers for their prompt discovery  ...  Key findings PET and CT Convolutional neural network (v-Net, w-Net) [30] 68 Ga-Pentixaflor PET/CT and DL techniques to detect MM whole-body bone lesions PET and CT Random Forest [31] Radiomics analysis  ... 
doi:10.3390/cancers14030606 pmid:35158874 pmcid:PMC8833500 fatcat:7hrerpowiffxlchep4vbb2h2si

AI-Based Detection, Classification and Prediction/Prognosis in Medical Imaging: Towards Radiophenomics [article]

Fereshteh Yousefirizi, Pierre Decazes, Amine Amyar, Su Ruan, Babak Saboury, Arman Rahmim
2022 arXiv   pre-print
This work reviews AI-based techniques, with a special focus on oncological PET and PET/CT imaging, for different detection, classification, and prediction/prognosis tasks.  ...  AI-based detection searches the image space to find the regions of interest based on patterns and features.  ...  Acknowledgements This project was in part supported by the Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery Grant RGPIN-2019-06467, and the Canadian Institutes of Health Research  ... 
arXiv:2110.10332v4 fatcat:vmpxhoolarbrve5ddyfn5umfim

Classifying functional nuclear images with convolutional neural networks: a survey

Qiang Lin, Zhengxing Man, Yongchun Cao, Tao Deng, Chengcheng Han, Chuangui Cao, Linjun Zhang, Sitao Zeng, Ruiting Gao, Weilan Wang, Jinshui Ji, Xiaodi Huang
2020 IET Image Processing  
Functional imaging has successfully been applied to capture functional changes in the pathological tissues of a body in recent years.  ...  Finally, they discuss research challenges and directions for developing technological solutions to classify nuclear medicine images based on the CNN technique.  ...  The results showed that W-Net can learn features from multimodal images for detecting multiple myeloma bone lesions.  ... 
doi:10.1049/iet-ipr.2019.1690 fatcat:i4h7n4hsc5b2lenwmzekybxwte

Abstracts of the Total Body PET conference 2018

2018 EJNMMI Physics  
magnitude higher than is possible with current generation PET/CT scanners.  ...  total-body PET imaging for both existing and new applications.  ...  We acknowledge the financial support by The Polish National Center for Acknowledgments This project has been developed on behalf of the J-PET Collaboration.  ... 
doi:10.1186/s40658-018-0218-7 pmid:29956037 pmcid:PMC6023806 fatcat:ecu5ob3twndqbjp25d5r37ugaq

Proceedings of the International Cancer Imaging Society Meeting and 20th Annual Teaching Course

2021 Cancer Imaging  
) genome with specific focus on the relevance for radiologists.  ...  Integration of genomic data into care of cancer patients is becoming routine practice and knowledge of cancer genomics is important for all radiologists.  ...  Units with this policy should robustly audit impact on patient outcomes. For patients with clinical stage 111 disease, a whole-body technique is indicated for staging.  ... 
doi:10.1186/s40644-021-00422-6 pmid:34535182 pmcid:PMC8446473 fatcat:u2xyfxglezhnnjlkls3ns6udq4

Proceedings of the International Cancer Imaging Society (ICIS) 18th Annual Teaching Course

2018 Cancer Imaging  
All of them underwent "Dual phase" PET-CT consisting of initial pelvis starting 20 minutes after the injection of 18 F-Choline followed by 1 hour delayed PET of the whole body.  ...  Conclusions: In our experience 18 FCH PET/CT is a useful tool to detect lesions in patients with biochemical progression but it seems to have limited value for staging.  ...  To evaluate the impact of PET/CT on clinical management based on a prospective data registry. The registry was developed to meet the requirements for PET/CT coverage by public health insurance.  ... 
doi:10.1186/s40644-018-0160-x fatcat:l3fdy44aunejnfamsnka5hfiwu

Proceedings of the World Molecular Imaging Congress 2020, October 7-9, 2020: General Abstracts

2022 Molecular Imaging and Biology  
Conclusion: Tumor specific uptake of pan800 provided remarkable contrast and a flexible imaging window for fluorescence-guided identification of HGGs despite modest EGFR expression.  ...  Administered systemically, nearinfrared fluorescent dye-labeled antibody targeting EGFR may be able to detect HGGs expressing modest amount of EGFR and serve as an image-guided surgical probe.  ...  We believe that our miniature microscope will herald a new era in preclinical brain disease research by enabling novel insights into the dysfunction of multiple neurobiological variables over the disease  ... 
doi:10.1007/s11307-021-01691-0 pmid:34982363 pmcid:PMC8725637 fatcat:ipn7hwekzzh6nbsk6dr2mzuhhm

Poster Presentations

2019 Journal of labelled compounds & radiopharmaceuticals  
ACKNOWLEDGMENTS LNCaP cells were kindly provided by Stem Cell Bank, Chinese Academy of Sciences. We are grateful to Soochow University for the help in micro-SPECT/CT imaging.  ...  Louis and University of Alabama Birmingham for providing 89 Zr; Hyosuk Seo for technical assistance; Yale PET Center for their support and training; and the NIH/NCI for funding (R00CA201601).  ...  Our research aims to evaluate the application of 68 Ga-pentixafor PET/CT in patients with PA, especially in APA.  ... 
doi:10.1002/jlcr.3725 fatcat:so6xn4oepngf3h7x5ei3pnd7bu

Special/Poster Abstracts

The average life expectancy of human beings has increased significantly over the past several decades due to the improved performance of medical equipment and the tremendous efforts of medical professionals  ...  Conclusions: We evaluated the regional target VOI analysis for CL scale. The variation of CL was found among brain regions.  ...  has not been done, this study patients showing a total number of 77 lesions detected by this method. 68Ga-DOTATATE PET/CT detected NET aimed to evaluate the detectability of lesions in each organ with  ... 
doi:10.18893/kakuigaku.59.s41 pmid:36002329 fatcat:vwq75w7n3rektgua5yy2v53dzm