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Voxelwise nonlinear regression toolbox for neuroimage analysis: Application to aging and neurodegenerative disease modeling [article]

Santi Puch, Asier Aduriz, Adrià Casamitjana, Veronica Vilaplana, Paula Petrone, Grégory Operto, Raffaele Cacciaglia, Stavros Skouras, Carles Falcon, José Luis Molinuevo, Juan Domingo Gispert
<span title="2017-04-18">2017</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
This paper describes a new neuroimaging analysis toolbox that allows for the modeling of nonlinear effects at the voxel level, overcoming limitations of methods based on linear models like the GLM.  ...  disease.  ...  Acknowledgements This work has been developed in the framework of the project BigGraph TEC2013-43935-R, funded by the Spanish Ministerio de Economia y Competitividad and the European Regional Development  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1612.00667v3">arXiv:1612.00667v3</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/prb34uehlfew5iazqzmk4rv6o4">fatcat:prb34uehlfew5iazqzmk4rv6o4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200824064605/https://arxiv.org/pdf/1612.00667v3.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/28/c3/28c361782b822cfa77bc16ea3321c96adcf6e31b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1612.00667v3" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>

A multivariate nonlinear mixed effects model for longitudinal image analysis: Application to amyloid imaging

Murat Bilgel, Jerry L. Prince, Dean F. Wong, Susan M. Resnick, Bruno M. Jedynak
<span title="">2016</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
We propose a multivariate nonlinear mixed effects model for estimating the trajectories of voxelwise neuroimaging biomarkers from longitudinal data that accounts for such differences across individuals  ...  This is especially important for neurodegenerative diseases, as therapeutic intervention is most likely to be effective in the preclinical disease stages prior to significant neuronal damage.  ...  Acknowledgment We thank Kalyani Kansal for her thorough review of the mathematical derivations and assistance with code testing.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2016.04.001">doi:10.1016/j.neuroimage.2016.04.001</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27095307">pmid:27095307</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4912927/">pmcid:PMC4912927</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/xx2syc2wk5hepnb6ocidz22yqi">fatcat:xx2syc2wk5hepnb6ocidz22yqi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190427031929/https://pdxscholar.library.pdx.edu/cgi/viewcontent.cgi?article=1158&amp;context=mth_fac" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/84/d9/84d96da4c663331a4cd6a6891ab1cfcf2f5b4805.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2016.04.001"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912927" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Comparison of quality control methods for automated diffusion tensor imaging analysis pipelines

Seyyed M. H. Haddad, Christopher J. M. Scott, Miracle Ozzoude, Melissa F. Holmes, Stephen R. Arnott, Nuwan D. Nanayakkara, Joel Ramirez, Sandra E. Black, Dar Dowlatshahi, Stephen C. Strother, Richard H. Swartz, Sean Symons (+4 others)
<span title="2019-12-20">2019</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
We concluded that this pipeline was the most robust and is preferred for automated analysis of multisite brain DTI data.  ...  For the simulated DTI datasets, the measure used to evaluate the performance of the pipelines was the normalized difference between the mean DTI metrics measured in GM and WM regions and the corresponding  ...  Acknowledgments The authors would like to thank all ONDRI participants including the ONDRI investigators and the ONDRI governing committees: executive committee; steering committee; publication  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0226715">doi:10.1371/journal.pone.0226715</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31860686">pmid:31860686</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6924651/">pmcid:PMC6924651</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/knvfsx4zrnandprikj2f5loscm">fatcat:knvfsx4zrnandprikj2f5loscm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210716011732/https://ir.lib.uwo.ca/cgi/viewcontent.cgi?article=1382&amp;context=biophysicspub" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/34/bd/34bd584387af24cf66f05ce3aff97d58cb014649.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0226715"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924651" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Investigating Neuroimaging Correlates of Early Frailty in Patients With Behavioral Variant Frontotemporal Dementia: A MRI and FDG-PET Study

Martina Amanzio, Sara Palermo, Mario Stanziano, Federico D'Agata, Antonello Galati, Salvatore Gentile, Giancarlo Castellano, Massimo Bartoli, Giuseppina Elena Cipriani, Elisa Rubino, Paolo Fonio, Innocenzo Rainero
<span title="2021-04-14">2021</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/xyafp6gbr5et3ghi4kqddnyolm" style="color: black;">Frontiers in Aging Neuroscience</a> </i> &nbsp;
and correlated to each other within patients.  ...  Linear regression of the MPI was performed on those voxels presenting a significant correlation between altered GM volume and metabolism.  ...  Voxelwise Correlation Between Frailty, Atrophy, and Hypometabolism A voxelwise regression of the MPI (adjusted for TICV, age, and time since diagnosis) was performed within patient group on those voxels  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnagi.2021.637796">doi:10.3389/fnagi.2021.637796</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33935684">pmid:33935684</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8079404/">pmcid:PMC8079404</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/qu7qygcw2nel5d2gujw5twqlg4">fatcat:qu7qygcw2nel5d2gujw5twqlg4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210420230619/https://fjfsdata01prod.blob.core.windows.net/articles/files/637796/pubmed-zip/.versions/1/.package-entries/fnagi-13-637796/fnagi-13-637796.pdf?sv=2018-03-28&amp;sr=b&amp;sig=YbLSoFDwKYxsRK1xN4BcXnCGBm%2FwMgRxD5hTlCEPLh4%3D&amp;se=2021-04-20T23%3A06%3A47Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fnagi-13-637796.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/52/28/5228a8625ec7e2094557049aa4ca1d6c32e76ab0.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fnagi.2021.637796"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079404" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker [article]

James H Cole, Rudra PK Poudel, Dimosthenis Tsagkrasoulis, Matthan WA Caan, Claire Steves, Tim D Spector, Giovanni Montana
<span title="2016-12-08">2016</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease  ...  CNN brain-predicted ages were generated and compared to a Gaussian Process Regression (GPR) approach, on all datasets.  ...  A key goal of neuroimaging research is to make tools for clinical application, that can provide objective and reliable information that clinicians can use to help when treating brain diseases.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1612.02572v1">arXiv:1612.02572v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/s7awsvx6cnb47ekhx5vsdqgu5u">fatcat:s7awsvx6cnb47ekhx5vsdqgu5u</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200906102709/https://arxiv.org/ftp/arxiv/papers/1612/1612.02572.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/c3/32/c3327b8f3c35ab0c458e27589956f8e1a30fa566.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1612.02572v1" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>

A Comprehensive Survey on Tools for Effective Alzheimer's Disease Detection

N. Vinutha, G. U. Vasanthakumar, P. Deepa Shenoy, K. R. Venugopal
<span title="2018-01-01">2018</span> <i title="Science Publications"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/lmfylpooojdnnktsqk6scjcnx4" style="color: black;">Neuroscience International</a> </i> &nbsp;
These tools focus on extracting and enhancing the relevant information from brain images, which facilitates neuroimaging experts to make better and quick decision for diagnosing enormous number of patients  ...  This brief review of tools gives a clear outlook for researchers to utilize existing techniques to handle the image data obtained from different modalities and focus further for improving and developing  ...  The corresponding author confirms that all of the other authors have read and approved the manuscript and there are no ethical issues involved.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3844/amjnsp.2018.1.10">doi:10.3844/amjnsp.2018.1.10</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ah2yddsyc5flvplzkkz3zaitda">fatcat:ah2yddsyc5flvplzkkz3zaitda</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190225233433/http://pdfs.semanticscholar.org/696a/eb9f59e42fab468febc2e157ae9a6d2b6909.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/69/6a/696aeb9f59e42fab468febc2e157ae9a6d2b6909.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3844/amjnsp.2018.1.10"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Individualized Gaussian process-based prediction and detection of local and global gray matter abnormalities in elderly subjects

G. Ziegler, G.R. Ridgway, R. Dahnke, C. Gaser
<span title="">2014</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
The approach aims at quantitative and trans-20 parent support for clinicians who aim to detect structural abnormalities in patients at risk of Alzheimer's 21 disease or other types of dementia.  ...  By supposing smooth 23 structural trajectories the models account for the general course of age-related structural decline as well as late-24 life accelerated loss.  ...  In order to preserve 535 the voxelwise scaling of the transformed data for further modeling 2 Data used in the preparation of this article were obtained from the Alzheimer's Disease Neuroimaging Initiative  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2014.04.018">doi:10.1016/j.neuroimage.2014.04.018</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/24742919">pmid:24742919</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4077633/">pmcid:PMC4077633</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mqtqmlxlijee3nvms2w6eczybi">fatcat:mqtqmlxlijee3nvms2w6eczybi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170812084938/http://www.neuro.uni-jena.de/pdf-files/Ziegler-NI14.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ac/2b/ac2bc25b0822efde4603888c2ea8a2352d5b734e.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2014.04.018"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077633" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Characterization of disease-related covariance topographies withSSMPCAtoolbox: Effects of spatial normalization and PET scanners

Shichun Peng, Yilong Ma, Phoebe G. Spetsieris, Paul Mattis, Andrew Feigin, Vijay Dhawan, David Eidelberg
<span title="2013-05-14">2013</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/wtsn7qcbmrhjppax2iuhu4xj2m" style="color: black;">Human Brain Mapping</a> </i> &nbsp;
In order to generate imaging biomarkers from disease-specific brain networks, we have implemented a general toolbox to rapidly perform scaled subprofile modeling (SSM) based on principal component analysis  ...  These patterns and subject scores were highly reproducible with different normalization programs in terms of disease discrimination and cognitive correlation.  ...  Acknowledgments This work was supported by NIH NS R01 35069 and RR M01 018535 awarded to The Feinstein Institute for Medical Research.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/hbm.22295">doi:10.1002/hbm.22295</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23671030">pmid:23671030</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3778048/">pmcid:PMC3778048</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mob63h7orbgepnehzth3r4nype">fatcat:mob63h7orbgepnehzth3r4nype</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200208015151/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3778048&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/95/74/95740cce79191732f234642b1baeb3094ee6dd1e.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/hbm.22295"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> wiley.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778048" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Alzheimer's disease: 3-Dimensional MRI texture for prediction of conversion from mild cognitive impairment

Collin C. Luk, Abdullah Ishaque, Muhammad Khan, Daniel Ta, Sneha Chenji, Yee-Hong Yang, Dean Eurich, Sanjay Kalra
<span title="2018-11-02">2018</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/y5b3apqmfve23ds3kch2bvmcxa" style="color: black;">Alzheimer&#39;s and Dementia: Diagnosis, Assessment and Disease Monitoring</a> </i> &nbsp;
Application of the composite model to ten randomly selected test groups (nonconverters = 26, converters = 24) predicted MCI conversion with a mean accuracy of 76.2%.  ...  A predictive model using texture and clinical factors was used to predict conversion of patients with MCI to AD. This model was then tested on ten randomly selected test groups from the data set.  ...  To test our discriminant model, we then applied these binary logistic regression models to their corresponding trial sets to determine their accuracy for distinguishing between MCI-NC and MCI-C.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.dadm.2018.09.002">doi:10.1016/j.dadm.2018.09.002</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30480081">pmid:30480081</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6240791/">pmcid:PMC6240791</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/hxahficwjfayhgioebyifjtnee">fatcat:hxahficwjfayhgioebyifjtnee</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200501073517/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6240791&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f3/72/f37265c8570046df698b75218b20339895d944ce.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.dadm.2018.09.002"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240791" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Modeling & Analysis

<span title="">2003</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
maps of CSF, PVL and SCL were computed for the categories (i) whole database; (ii) gender; (iii) age-intervals for the whole data base and (iv) age-intervals for each gender.  ...  We analyzed these time courses with a similar model, but without low-pass filtering, using the MarsBar SPM toolbox.  ...  , age 31.8±14.2 years).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/s1053-8119(05)70006-9">doi:10.1016/s1053-8119(05)70006-9</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/zff2suxcofbxvetfrwfwcxi3zm">fatcat:zff2suxcofbxvetfrwfwcxi3zm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170706082412/http://www.math.fsu.edu/%7Emhurdal/presentations/hbm/hbm03/hbm03_neuroimage_abstracts.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/s1053-8119(05)70006-9"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a>

Subregional neuroanatomical change as a biomarker for Alzheimer's disease

D. Holland, J. B. Brewer, D. J. Hagler, C. Fennema-Notestine, A. M. Dale
<span title="2009-11-20">2009</span> <i title="Proceedings of the National Academy of Sciences"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/nvtuoas5pbdsllkntnhizy4f4q" style="color: black;">Proceedings of the National Academy of Sciences of the United States of America</a> </i> &nbsp;
Thanks to Alan Koyama, Robin Jennings, and Chris Pung for downloading and processing the Alzheimer's Disease Neuroimaging Initiative MRI data.  ...  Data collection and sharing for this project was funded by the Alzheimer's Disease Neuroimaging Initiative (ADNI) (National Institute of Health Grant U01 AG024904).  ...  The first, Model T (for ''total''), assumes that the study drug modifies both disease-and aging-related changes; the second, Model D (for ''disease-specific''), assumes that the study drug modifies AD-or  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1073/pnas.0906053106">doi:10.1073/pnas.0906053106</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/19996185">pmid:19996185</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2791580/">pmcid:PMC2791580</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/i366bsmy6vhstb5yzhlu6egtlq">fatcat:i366bsmy6vhstb5yzhlu6egtlq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180726141759/http://www.pnas.org/content/pnas/106/49/20954.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/1a/03/1a0356d36dfc6894184ed80bdbfac787f39f81e2.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1073/pnas.0906053106"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791580" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Multiparametric graph theoretical analysis reveals altered structural and functional network topology in Alzheimer's disease

Shih-Yen Lin, Chen-Pei Lin, Tsung-Jen Hsieh, Chung-Fen Lin, Sih-Huei Chen, Yi-Ping Chao, Yong-Sheng Chen, Chih-Cheng Hsu, Li-Wei Kuo
<span title="2019-01-25">2019</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/47gmsc3hojdm5kdlgbg4peyvyi" style="color: black;">NeuroImage: Clinical</a> </i> &nbsp;
Alzheimer's disease (AD), an irreversible neurodegenerative disease, is the most common type of dementia in elderly people.  ...  We compared Pearson correlation and covariance by investigating their sensitivities to functional network topology.  ...  Chiu-Tien Hsu for his help in data acquisition, Dr. Chien-Yuan Lin for his help in MR protocol settings and Dr.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.nicl.2019.101680">doi:10.1016/j.nicl.2019.101680</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30710870">pmid:30710870</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6357901/">pmcid:PMC6357901</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ohqosbx5zjgzljmx67vrjby7vu">fatcat:ohqosbx5zjgzljmx67vrjby7vu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200505114903/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6357901&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/c8/83/c883ec43a6b768fd47a47234726346caebf247a9.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.nicl.2019.101680"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357901" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

PET Imaging of Neuropathology in Tauopathies: Progressive Supranuclear Palsy

Vladimir Kepe, Yvette Bordelon, Adam Boxer, Sung-Cheng Huang, Jie Liu, Frederick C. Thiede, John C. Mazziotta, Mario F. Mendez, Natacha Donoghue, Gary W. Small, Jorge R. Barrio
<span title="2013-06-04">2013</span> <i title="IOS Press"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/uux5o5kf5zaednhl4637xcmbte" style="color: black;">Journal of Alzheimer&#39;s Disease</a> </i> &nbsp;
Voxelwise volume-based morphometry, surface-based morphometry, and DTI correlations were performed with 18 F-AV1451 binding in typical PSP regions of interest (putamen, thalamus and dentate cerebellum)  ...  Methods Twenty-three people with clinically probable PSP-Richardson's syndrome (age 68.8 ± 5.8 years, 39% female) and 23 controls underwent structural 3 T brain MRI including DTI.  ...  We thank the NIHR Dementias and Neurodegenerative. Diseases Research Network for help with subject recruitment.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3233/jad-130032">doi:10.3233/jad-130032</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23579330">pmid:23579330</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3674205/">pmcid:PMC3674205</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/o7lhyody3zf25f5gmupuemmfqm">fatcat:o7lhyody3zf25f5gmupuemmfqm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200326180302/https://link.springer.com/content/pdf/10.1007%2Fs00415-019-09566-9.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d1/77/d1776b854842bdb3271e9bc3ffaa1be29887e14a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3233/jad-130032"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674205" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

18F-AV1451 PET imaging and multimodal MRI changes in progressive supranuclear palsy

Nicolas Nicastro, Patricia Vazquez Rodriguez, Maura Malpetti, William Richard Bevan-Jones, P. Simon Jones, Luca Passamonti, Franklin I. Aigbirhio, John T. O'Brien, James B. Rowe
<span title="2019-10-22">2019</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/eh5waxus3falngptlhwrp2e75a" style="color: black;">Journal of Neurology</a> </i> &nbsp;
Voxelwise volume-based morphometry, surface-based morphometry, and DTI correlations were performed with 18F-AV1451 binding in typical PSP regions of interest (putamen, thalamus and dentate cerebellum).  ...  Twenty-three people with clinically probable PSP-Richardson's syndrome (age 68.8 ± 5.8 years, 39% female) and 23 controls underwent structural 3 T brain MRI including DTI.  ...  We thank the NIHR Dementias and Neurodegenerative. Diseases Research Network for help with subject recruitment.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s00415-019-09566-9">doi:10.1007/s00415-019-09566-9</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31641878">pmid:31641878</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6989441/">pmcid:PMC6989441</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/dom7cv44aja4lct4onfxz2stki">fatcat:dom7cv44aja4lct4onfxz2stki</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200508062040/https://archive-ouverte.unige.ch/files/downloads/0/0/1/3/1/7/0/6/unige_131706_attachment01.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f6/63/f663ff4b0268c7372b169aa47b52a82d6f10102b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s00415-019-09566-9"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989441" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Predictive markers for AD in a multi-modality framework: An analysis of MCI progression in the ADNI population

Chris Hinrichs, Vikas Singh, Guofan Xu, Sterling C. Johnson
<span title="">2011</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
Alzheimer's Disease (AD) and other neurodegenerative diseases affect over 20 million people worldwide, and this number is projected to significantly increase in the coming decades.  ...  Our experiments reveal that this measure shows significant group differences between MCI subjects who progressed to AD, and those who remained stable for 3 years.  ...  Data collection and sharing for this project was funded by the Alzheimer's Disease Neuroimaging Initiative (ADNI) (National Institutes of Health Grant U01 AG024904).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2010.10.081">doi:10.1016/j.neuroimage.2010.10.081</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/21146621">pmid:21146621</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3035743/">pmcid:PMC3035743</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/kmqgz776p5hwljd7ciokarxb5e">fatcat:kmqgz776p5hwljd7ciokarxb5e</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20150506221232/http://pages.cs.wisc.edu/~hinrichs/papers/MKL_ADNI.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/bb/cf/bbcf8bbe9247b326465d1d42483bbadf1c0e9b59.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2010.10.081"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035743" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>
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