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Vito – A Generic Agent for Multi-physics Model Personalization: Application to Heart Modeling [chapter]

Dominik Neumann, Tommaso Mansi, Lucian Itu, Bogdan Georgescu, Elham Kayvanpour, Farbod Sedaghat-Hamedani, Jan Haas, Hugo Katus, Benjamin Meder, Stefan Steidl, Joachim Hornegger, Dorin Comaniciu
2015 Lecture Notes in Computer Science  
We propose to use, for the first time to our knowledge, artificial intelligence (AI) concepts to learn how to personalize a computational model, inspired by how an expert manually personalizes.  ...  Because the algorithm is model-independent, personalizing a completely new model would require only adjusting some simple parameters of the agent and defining the observations to match, without the full  ...  Vito is generic in the sense that beyond minimal user input (parameter ranges and authorized updates, discretization bins), it is able to learn by itself how to personalize a model.  ... 
doi:10.1007/978-3-319-24571-3_53 fatcat:d33cthvl4fgyxey5lddtlrvysi

A self-taught artificial agent for multi-physics computational model personalization

Dominik Neumann, Tommaso Mansi, Lucian Itu, Bogdan Georgescu, Elham Kayvanpour, Farbod Sedaghat-Hamedani, Ali Amr, Jan Haas, Hugo Katus, Benjamin Meder, Stefan Steidl, Joachim Hornegger (+1 others)
2016 Medical Image Analysis  
Personalization is the process of fitting a model to patient data, a critical step towards application of multi-physics computational models in clinical practice.  ...  The agent then automatically learns an optimal strategy for on-line personalization.  ...  Time-varying elastance models were used for all four chambers of the heart. The valves were modeled through a resistance and an inertance.  ... 
doi:10.1016/j.media.2016.04.003 pmid:27133269 fatcat:dzg4637x5jev5nkcjpvtpncxee

A Self-Taught Artificial Agent for Multi-Physics Computational Model Personalization [article]

Dominik Neumann, Tommaso Mansi, Lucian Itu, Bogdan Georgescu, Elham Kayvanpour, Farbod Sedaghat-Hamedani, Ali Amr, Jan Haas, Hugo Katus, Benjamin Meder, Stefan Steidl, Joachim Hornegger (+1 others)
2016 arXiv   pre-print
Personalization is the process of fitting a model to patient data, a critical step towards application of multi-physics computational models in clinical practice.  ...  The agent then automatically learns an optimal strategy for on-line personalization.  ...  with automated kernel bandwidth estimation, see Kristan et al. (2011) for more details.  ... 
arXiv:1605.00303v1 fatcat:vikeeupvzjh2hcwgb6eufmt5kq

Nature as God: A juxtaposition of Vito Mancuso and Alexander von Humboldt in their search for understanding reality

Johan Buitendag, Corneliu C. Simut
2021 HTS Teologiese Studies/Theological Studies  
A method of polycentric hermeneutics is thus pursued.Although we referred to the concept of consilience regarding von Humboldt's enterprise, it is not in the authors' scope to achieve this with science  ...  the thought constructs of a scientist and a theologian are juxtaposed.  ...  Data availability Data sharing is not applicable to this article as no new data were created or analysed in this study.  ... 
doi:10.4102/hts.v77i3.6525 fatcat:5dfxwhi755gjvnfhqbnwunsbh4

Networks beyond pairwise interactions: structure and dynamics [article]

Federico Battiston, Giulia Cencetti, Iacopo Iacopini, Vito Latora, Maxime Lucas, Alice Patania, Jean-Gabriel Young, Giovanni Petri
2020 arXiv   pre-print
We review the measures designed to characterize the structure of these systems and the models proposed in the literature to generate synthetic structures, such as random and growing simplicial complexes  ...  We elucidate the relations between higher-order topology and dynamical properties, and conclude with a summary of empirical applications, providing an outlook on current modeling and conceptual frontiers  ...  Two persons can share one or more common linking events. For instance, person P 20 is linked at dimension 0 to person P 4 since they have only a node (event 3) in common.  ... 
arXiv:2006.01764v1 fatcat:h4ezvequxrbyrozpjbb6lbqhj4

Networks beyond pairwise interactions: Structure and dynamics

Federico Battiston, Giulia Cencetti, Iacopo Iacopini, Vito Latora, Maxime Lucas, Alice Patania, Jean-Gabriel Young, Giovanni Petri
2020 Physics reports  
We conclude with a summary of empirical applications, and an outlook on current modeling and conceptual frontiers.  ...  We review the measures designed to characterize the structure of these systems and the models proposed to generate synthetic structures, such as random and growing bipartite graphs, hypergraphs and simplicial  ...  Two persons can share one or more common linking events. For instance, person P 20 is linked at dimension 0 to person P 4 since they have only a node (event 3) in common.  ... 
doi:10.1016/j.physrep.2020.05.004 fatcat:pkugz4i5obainmcrwod6i4od7q

Mechanisms and Clinical Implications of Endothelial Dysfunction in Arterial Hypertension

Pasquale Ambrosino, Tiziana Bachetti, Silvestro Ennio D'Anna, Brurya Galloway, Andrea Bianco, Vito D'Agnano, Antimo Papa, Andrea Motta, Fabio Perrotta, Mauro Maniscalco
2022 Journal of Cardiovascular Development and Disease  
The aim of this review is to summarize the pathophysiology of the relationship between endothelial dysfunction and systemic arterial hypertension, with a focus on the personalized pharmacological and rehabilitation  ...  Endothelial cells display important homeostatic functions, since they are able to respond to humoral and hemodynamic stimuli.  ...  We thank the copyright holder for this relevant contribution. Conflicts of Interest: The authors declare no conflict of interest. J. Cardiovasc. Dev. Dis. 2022, 9, 136  ... 
doi:10.3390/jcdd9050136 fatcat:f3lhpmv2pfcx7dlf4e6ig7lova

Using Dollars to Fight Drugs: The Dysfunctional Aspects of Drug Policy Making

Gary Potter, Larry K. Games, Gennaro F. Vito
1992 Journal of Contemporary Criminal Justice  
Offender Treatment $337,100* (TASC Model) (Multi-jurisdictional) Pretrial Drug Detention Program $265,000* (Multi-jurisdictional) Total $3,375,600* * These figures include the 25 percent state and local  ...  Summary of report on narcotics trafficking for the eastern and western districts of Kentucky. A report submitted to the Attorney General of the United States. Diegelman, R.F. (1982).  ... 
doi:10.1177/104398629200800405 fatcat:7icvhl757ng6bllfzn5h2jv5gq

An ontology-based analysis and semantics for organizational structure modeling in the ARIS method

Paulo Sérgio Santos, João Paulo A. Almeida, Giancarlo Guizzardi
2013 Information Systems  
of the language to resolve the issues identified.  ...  This paper focuses on the issue of ontological analysis for organizational structure modeling in the ARIS method with the following contributions: (i) an interpretation of the language in terms of real-world  ...  Communicative acts can also be used to distinguish between physical agents (e.g., a person, a dog) and social agents (e.g., an organization, a society).  ... 
doi:10.1016/j.is.2012.09.004 fatcat:xhd63mot5nf3rldgzgnjxigkmu

A mobile bazaar for wide-area wireless services

Rajiv Chakravorty, Sulabh Agarwal, Suman Banerjee, Ian Pratt
2006 Wireless networks  
heart of MoB is an open market architecture 14 in which mobile users can opportunistically trade various 15 services with each other in a flexible manner.  ...  MoB proposes to 7 change the current model of data services in the following 8 fundamental ways: (1) it decouples infrastructure providers 9 from services providers and enables fine-grained competi-10  ...  Our design of this 305 system is modeled on eBay (see http://www.ebay.com)-a 306 large person-to-person online auction site (with more than 4 307 million open auctions at a time), which implements its  ... 
doi:10.1007/s11276-006-9853-3 fatcat:p2uxgp6ydravpcyqjeul673vge

MoB

Rajiv Chakravorty, Sulabh Agarwal, Suman Banerjee, Ian Pratt
2005 Proceedings of the 11th annual international conference on Mobile computing and networking - MobiCom '05  
At the heart of MoB is an open market architecture in which mobile users can opportunistically trade various services with each other in a flexible manner.  ...  MoB proposes to change the current model of data services in the following fundamental ways: (1) it decouples infrastructure providers from services providers and enables finegrained competition, (2) it  ...  We also thank the anonymous reviewers and our shepherd, Sujata Banerjee, for valuable feedback.  ... 
doi:10.1145/1080829.1080854 dblp:conf/mobicom/ChakravortyABP05 fatcat:5j6pasvx5zcb7mjp2qlwmby62m

SMART PANDEMIC MANAGEMENT THROUGH A SMART, RESILIENT AND FLEXIBLE DECISION-MAKING SYSTEM

G. Mezzour, Z. Boudanga, S. Benhadou
2020 The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences  
on a large scale, merging cyber and physical spaces.  ...  Through this paper we explored the potential of digital twins for the development of a new vision of world global dynamics under the aegis of a virus whose parameters are still elusive to date.  ...  Regulated outputs generated by the interactions between its three agents are communicated to smart city agents' shadows, which constitute a dynamic simulation of physical agents and their associated logic  ... 
doi:10.5194/isprs-archives-xliv-4-w3-2020-285-2020 fatcat:wg4akpetzjhwbnagdbcjynkqcy

High-Risk Multiple Myeloma: Integrated Clinical and Omics Approach Dissects the Neoplastic Clone and the Tumor Microenvironment

Antonio Giovanni Solimando, Matteo Claudio Da Vià, Sebastiano Cicco, Patrizia Leone, Giuseppe Di Lernia, Donato Giannico, Vanessa Desantis, Maria Antonia Frassanito, Arcangelo Morizio, Julia Delgado Tascon, Assunta Melaccio, Ilaria Saltarella (+8 others)
2019 Journal of Clinical Medicine  
We also summarize the existing multi-omics-based risk profiling tools, in order to better select candidates for dual immune/vasculogenesis targeting.  ...  The comprehensive understanding of the genetic heterogeneity and MM high-risk ecosystem enforce a systematic bench-to-bedside approach. Here, we provide a broad outlook of novel druggable targets.  ...  Acknowledgments: We thank Mary Victoria Pragnell, BA, at the School of Medicine and Surgery at University of Bari, and Mary Ann D'Costa, in Literature and Intercultural Translation, for linguistic revision  ... 
doi:10.3390/jcm8070997 pmid:31323969 pmcid:PMC6678140 fatcat:xogiatfj3je5zn5fa3yrk7zhvu

[RO-MAN 2020 Front matter]

2020 2020 29th IEEE International Conference on Robot and Human Interactive Communication (RO-MAN)  
Thanks to its characteristics that fit very well the multi-agent systems, blockchain technologies show great potential for making robotic applications more open, trustworthy, secure and tolerant to faults  ...  It will be an opportunity to discuss methodologies and approaches to achieve a high quality of interaction, as well as how to combine different qualitative and quantitative metrics for a general evaluation  ... 
doi:10.1109/ro-man47096.2020.9223538 fatcat:bjcxi6mwajbc3gsolnvcxk4k4a

Molecular and Nonmolecular Imaging of Macrophages in Atherosclerosis

Zhaoyue Li, Hao Tang, Yingfeng Tu
2021 Frontiers in Cardiovascular Medicine  
Atherosclerosis is a major cause of ischemic heart disease, and the increasing medical burden associated with atherosclerotic cardiovascular disease has become a major public health concern worldwide.  ...  In this review, we highlight recent methods and research hotspots in molecular and nonmolecular imaging of macrophages in atherosclerosis that have enormous potential for rapid clinical application.  ...  This study was supported by the National Natural Science Foundation of China (81671746 and 81871402); the National Key R&D Program of China (2016YFC1301100); Scientific Research Foundation for Postdoctoral  ... 
doi:10.3389/fcvm.2021.670639 pmid:34095259 pmcid:PMC8169961 fatcat:ikmwtep7ibf6hleiuaikumxjyy
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