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Sound–meaning association biases evidenced across thousands of languages
2016
Proceedings of the National Academy of Sciences of the United States of America
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It is widely assumed that one of the fundamental properties of spoken language is the arbitrary relation between sound and meaning. ...
spoken in the world today. ...
For example, word-initial gl-in English evokes the idea of a visual phenomenon (as in glare, glance, glimmer) (7) . ...
doi:10.1073/pnas.1605782113
pmid:27621455
pmcid:PMC5047153
fatcat:4okfkpk35bbqrhj4dusbmj5pnm
Two bits: the cultural significance of free software
2008
ChoiceReviews
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necessity in order to install, run, or repair it. ...
this analysis of the programming language tcl/tk: It's also not clear that the primary design criterion in tcl, perl, or Visual BASIC was visual beauty-nor, probably, should it have been. ...
." 11 The genealogy of the term commons has a number of sources. ...
doi:10.5860/choice.46-2158
fatcat:jtxrurovzvexbm7lslgffroqem
Bioinformatics and Management Science: Some Common Tools and Techniques
2004
Operations Research
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The current challenge is to utilize the genome data to its full extent and to develop tools that improve our understanding of biological pathways and accelerate drug discovery. ...
Subject classifications: analysis of algorithms: computational complexity; dynamic programming: Markov, health care; diagnosis: pharmaceutical, probability, stochastic model applications. ...
In particular, special thanks to Michael Levitt for his suggestions on energy landscapes and providing many of the images used; Joe Felsenstein, Persi Diaconis, and Mike Steel for various discussions on ...
doi:10.1287/opre.1030.0095
fatcat:ipvug7vnbjecfh3x6oa247hnq4
Population Genomics: Whole-Genome Analysis of Polymorphism and Divergence in Drosophila simulans
2007
PLoS Biology
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Finally, we characterized genomic patterns of base composition for coding and noncoding sequence. ...
Our analysis suggests that adaptive protein evolution is common and is often related to biological processes that may be associated with gene expression, chromosome biology, and reproduction. ...
Estimates of Polymorphism, Divergence, and Counts of Polymorphic and Fixed Sites for CDS Found at doi: 10 Population Genomics of D. simulans melanogaster alignment was by CND and LP. ...
doi:10.1371/journal.pbio.0050310
pmid:17988176
pmcid:PMC2062478
fatcat:cs7finhyyrfpxpoqtxniwpivja
Genome Evolution
[chapter]
2013
Bioinformatics and Molecular Evolution
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The actual time taken will depend on how good the programmer is, what language the program is written in, and what computer runs the program. Nevertheless, the time will always scale with N 2 . ...
evolutionarily. ...
code). ...
doi:10.1002/9781118697078.ch12
fatcat:lqzsmryir5cm5cp4q6y6prqowa
Describing Genomic and Epigenomic Traits Underpinning Emerging Fungal Pathogens
[chapter]
2017
Advances in Genetics
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In contrast, 89 ongoing surveillance and genotyping of crop pathogens is used to detect and map 90 the spread of phytopathogenic fungi and their lineages as they spread via trade and 91 transportation, ...
Crucially, in both animal and 93 plant systems, rapid genome sequencing is essential to gain a greater understanding 94 of the taxonomy, epidemiology and evolutionary biology of EFPs, and to inform 95 ...
DoS is based on the 1047 McDonald-Kreitman (MK) test, where the count of fixed synonymous (Ds) and fixed 1048 non-synonymous (Dn) is used in conjunction with the numbers of polymorphisms (in 1049 this ...
doi:10.1016/bs.adgen.2017.09.009
pmid:29153405
fatcat:zxalhdwe2bcfxdmuc6ikbb5qjy
General sessions (1B-01 - 3F-12)
2011
Genes & Genetic Systems
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But MSH3 homolog have been identified in C. elegans and it is not clear how they repair large insertion / deletion. ...
, Kouji 1 ( 1 Program in Life Sci., Grad. ...
Expression analysis showed that expression of Stra8, which is required for meiotic initiation, is significantly reduced in juvenile C57BL/6J-ChrX MSM and C57BL/6J-ChrXT MSM testes. ...
doi:10.1266/ggs.86.407
fatcat:wcfsqf2edvffdfqeoz7hqdld5e
Computing the origin and evolution of the ribosome from its structure — Uncovering processes of macromolecular accretion benefiting synthetic biology
2015
Computational and Structural Biotechnology Journal
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Accretion occurs pervasively in nature at widely different timeframes. The process also manifests in the evolution of macromolecules. ...
The early rise of the ribosomal 'turnstile' suggests an evolutionary transition in natural biological computation. ...
Computational biology is supported by grants from NSF (OISE-1172791 and DBI-1041233) and USDA (ILLU-802-909). ...
doi:10.1016/j.csbj.2015.07.003
pmid:27096056
pmcid:PMC4823900
fatcat:7va5wppmbzfanopc256f4tf644
Glossary of medical and molecular genetics
2011
Atlas of Genetics and Cytogenetics in Oncology and Haematology
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The amount of gene product is used to measure how active a gene is; abnormal amounts can be correlated with disease-causing alleles. ...
DNA repair (French: réparation de l'ADN) Genes encoding proteins that correct errors in DNA sequencing. ...
doi:10.4267/2042/38176
fatcat:x3vf2djgzrcmxferfsd6e7ivau
Molecular Characterization of Brain and other Structures in Vertebrates and Invertebrates
2019
Archives in Neurology & Neuroscience
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Pro-fibrotic mediator is the TGF beta, released by macro-phages and by any damaged tissue between surfaces named interstitium. ...
response or in transplantation. ...
Given that clotting is associated with both tissue repair and regeneration, it is unclear how clotting factors specifically drive regenerative processes instead of permanent scar formation. ...
doi:10.33552/ann.2019.03.000572
fatcat:ofxaonqwmfawjgdj77c2p6ivwq
General sessions (1A-01 - 3E12)
2009
Genes & Genetic Systems
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The DNA binding domain is located in the C-terminal region of Rep, and it has been suggested that the primase domain is located in the N-terminal region of Rep. ...
In E. coli, ATP-DnaA forms a specific multimeric complex on the origin (oriC), resulting in an initiation complex which is competent in the replicational initiation. ...
We were interested in how HR, NHEJ and MRX related to repair of DNA damage arising from ion irradiation in N. crassa. ...
doi:10.1266/ggs.84.433
fatcat:z5ou4zjhpjcgzl5fx67xj25lmq
Nmf9 Encodes a Highly Conserved Protein Important to Neurological Function in Mice and Flies
2015
PLoS Genetics
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and Jun Zhao in the UCSD Moores Cancer Center Transgenic Mouse Shared Resource for assistance in creating genome-edited mice; Wilson Clements and David Traver for zebrafish embryos, ISH protocols and ...
Acknowledgments We thank Amanda Roberts in the La Jolla Interdisciplinary Neuroscience Behavior Core at the Scripps Research Institute for consultation and assistance with behavioral assays; Ella Kothari ...
Sliding window analysis of relative constraint across the protein coding sequence showed that the skipped exon encodes the most evolutionarily constrained peptide sequence among Nmf9 homologs and genome ...
doi:10.1371/journal.pgen.1005344
pmid:26131556
pmcid:PMC4488434
fatcat:4tgsreatfbbf3fwiccky7nfy7a
Sanger – Dideoxy Chain Termination Sequencing
[chapter]
2018
Molecular Life Sciences
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Conventionally, the medium-scale structural unit of a polypeptide chain is referred to as its secondary structure. ...
The proper function of proteins is critical to life itself. What kinds of structures can a polymer made of amino acids adopt? ...
This ability to find genes that match in different individuals is important not only for genealogy but for understanding the genes themselves. ...
doi:10.1007/978-1-4614-1531-2_100145
fatcat:54afduv5wbghda5nkcytqipgpi
Synthesis of Modified Oligonucleotides
[chapter]
2018
Molecular Life Sciences
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The file type is application/pdf.
Conventionally, the medium-scale structural unit of a polypeptide chain is referred to as its secondary structure. ...
The proper function of proteins is critical to life itself. What kinds of structures can a polymer made of amino acids adopt? ...
This ability to find genes that match in different individuals is important not only for genealogy but for understanding the genes themselves. ...
doi:10.1007/978-1-4614-1531-2_255
fatcat:drah2ovdmbffxaxhmweseif6lq
General sessions (1A-01 - 3E-13)
2005
Genes & Genetic Systems
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The numbers of SNPs affecting ORF were about two-fold larger in genes with duplicates compared with those without duplicate genes (singleton genes). ...
Large-scale analysis of human SNPs with possible effects on gene function Using dbSNP and the gene structure of more than 21,000 human genes that were revealed in the annotation project of human fulllength ...
fixed region in the replication origin (ori). ...
doi:10.1266/ggs.80.444
fatcat:yec7vkgtjrbmllw2jgztcp5u2i
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