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Sound–meaning association biases evidenced across thousands of languages

Damián E. Blasi, Søren Wichmann, Harald Hammarström, Peter F. Stadler, Morten H. Christiansen
2016 Proceedings of the National Academy of Sciences of the United States of America  
It is widely assumed that one of the fundamental properties of spoken language is the arbitrary relation between sound and meaning.  ...  spoken in the world today.  ...  For example, word-initial gl-in English evokes the idea of a visual phenomenon (as in glare, glance, glimmer) (7) .  ... 
doi:10.1073/pnas.1605782113 pmid:27621455 pmcid:PMC5047153 fatcat:4okfkpk35bbqrhj4dusbmj5pnm

Two bits: the cultural significance of free software

2008 ChoiceReviews  
necessity in order to install, run, or repair it.  ...  this analysis of the programming language tcl/tk: It's also not clear that the primary design criterion in tcl, perl, or Visual BASIC was visual beauty-nor, probably, should it have been.  ...  ." 11 The genealogy of the term commons has a number of sources.  ... 
doi:10.5860/choice.46-2158 fatcat:jtxrurovzvexbm7lslgffroqem

Bioinformatics and Management Science: Some Common Tools and Techniques

Ali E. Abbas, Susan P. Holmes
2004 Operations Research  
The current challenge is to utilize the genome data to its full extent and to develop tools that improve our understanding of biological pathways and accelerate drug discovery.  ...  Subject classifications: analysis of algorithms: computational complexity; dynamic programming: Markov, health care; diagnosis: pharmaceutical, probability, stochastic model applications.  ...  In particular, special thanks to Michael Levitt for his suggestions on energy landscapes and providing many of the images used; Joe Felsenstein, Persi Diaconis, and Mike Steel for various discussions on  ... 
doi:10.1287/opre.1030.0095 fatcat:ipvug7vnbjecfh3x6oa247hnq4

Population Genomics: Whole-Genome Analysis of Polymorphism and Divergence in Drosophila simulans

David J Begun, Alisha K Holloway, Kristian Stevens, LaDeana W Hillier, Yu-Ping Poh, Matthew W Hahn, Phillip M Nista, Corbin D Jones, Andrew D Kern, Colin N Dewey, Lior Pachter, Eugene Myers (+2 others)
2007 PLoS Biology  
Finally, we characterized genomic patterns of base composition for coding and noncoding sequence.  ...  Our analysis suggests that adaptive protein evolution is common and is often related to biological processes that may be associated with gene expression, chromosome biology, and reproduction.  ...  Estimates of Polymorphism, Divergence, and Counts of Polymorphic and Fixed Sites for CDS Found at doi: 10 Population Genomics of D. simulans melanogaster alignment was by CND and LP.  ... 
doi:10.1371/journal.pbio.0050310 pmid:17988176 pmcid:PMC2062478 fatcat:cs7finhyyrfpxpoqtxniwpivja

Genome Evolution [chapter]

Paul G. Higgs, Teresa K. Attwood
2013 Bioinformatics and Molecular Evolution  
The actual time taken will depend on how good the programmer is, what language the program is written in, and what computer runs the program. Nevertheless, the time will always scale with N 2 .  ...  evolutionarily.  ...  code).  ... 
doi:10.1002/9781118697078.ch12 fatcat:lqzsmryir5cm5cp4q6y6prqowa

Describing Genomic and Epigenomic Traits Underpinning Emerging Fungal Pathogens [chapter]

Rhys A. Farrer, Matthew C. Fisher
2017 Advances in Genetics  
In contrast, 89 ongoing surveillance and genotyping of crop pathogens is used to detect and map 90 the spread of phytopathogenic fungi and their lineages as they spread via trade and 91 transportation,  ...  Crucially, in both animal and 93 plant systems, rapid genome sequencing is essential to gain a greater understanding 94 of the taxonomy, epidemiology and evolutionary biology of EFPs, and to inform 95  ...  DoS is based on the 1047 McDonald-Kreitman (MK) test, where the count of fixed synonymous (Ds) and fixed 1048 non-synonymous (Dn) is used in conjunction with the numbers of polymorphisms (in 1049 this  ... 
doi:10.1016/bs.adgen.2017.09.009 pmid:29153405 fatcat:zxalhdwe2bcfxdmuc6ikbb5qjy

General sessions (1B-01 - 3F-12)

2011 Genes & Genetic Systems  
But MSH3 homolog have been identified in C. elegans and it is not clear how they repair large insertion / deletion.  ...  , Kouji 1 ( 1 Program in Life Sci., Grad.  ...  Expression analysis showed that expression of Stra8, which is required for meiotic initiation, is significantly reduced in juvenile C57BL/6J-ChrX MSM and C57BL/6J-ChrXT MSM testes.  ... 
doi:10.1266/ggs.86.407 fatcat:wcfsqf2edvffdfqeoz7hqdld5e

Computing the origin and evolution of the ribosome from its structure — Uncovering processes of macromolecular accretion benefiting synthetic biology

Gustavo Caetano-Anollés, Derek Caetano-Anollés
2015 Computational and Structural Biotechnology Journal  
Accretion occurs pervasively in nature at widely different timeframes. The process also manifests in the evolution of macromolecules.  ...  The early rise of the ribosomal 'turnstile' suggests an evolutionary transition in natural biological computation.  ...  Computational biology is supported by grants from NSF (OISE-1172791 and DBI-1041233) and USDA (ILLU-802-909).  ... 
doi:10.1016/j.csbj.2015.07.003 pmid:27096056 pmcid:PMC4823900 fatcat:7va5wppmbzfanopc256f4tf644

Glossary of medical and molecular genetics

L Dallaire
2011 Atlas of Genetics and Cytogenetics in Oncology and Haematology  
The amount of gene product is used to measure how active a gene is; abnormal amounts can be correlated with disease-causing alleles.  ...  DNA repair (French: réparation de l'ADN) Genes encoding proteins that correct errors in DNA sequencing.  ... 
doi:10.4267/2042/38176 fatcat:x3vf2djgzrcmxferfsd6e7ivau

Molecular Characterization of Brain and other Structures in Vertebrates and Invertebrates

Luisetto M
2019 Archives in Neurology & Neuroscience  
Pro-fibrotic mediator is the TGF beta, released by macro-phages and by any damaged tissue between surfaces named interstitium.  ...  response or in transplantation.  ...  Given that clotting is associated with both tissue repair and regeneration, it is unclear how clotting factors specifically drive regenerative processes instead of permanent scar formation.  ... 
doi:10.33552/ann.2019.03.000572 fatcat:ofxaonqwmfawjgdj77c2p6ivwq

General sessions (1A-01 - 3E12)

2009 Genes & Genetic Systems  
The DNA binding domain is located in the C-terminal region of Rep, and it has been suggested that the primase domain is located in the N-terminal region of Rep.  ...  In E. coli, ATP-DnaA forms a specific multimeric complex on the origin (oriC), resulting in an initiation complex which is competent in the replicational initiation.  ...  We were interested in how HR, NHEJ and MRX related to repair of DNA damage arising from ion irradiation in N. crassa.  ... 
doi:10.1266/ggs.84.433 fatcat:z5ou4zjhpjcgzl5fx67xj25lmq

Nmf9 Encodes a Highly Conserved Protein Important to Neurological Function in Mice and Flies

Shuxiao Zhang, Kevin D. Ross, Glen A. Seidner, Michael R. Gorman, Tiffany H. Poon, Xiaobo Wang, Elizabeth M. Keithley, Patricia N. Lee, Mark Q. Martindale, William J. Joiner, Bruce A. Hamilton, Gregory P. Copenhaver
2015 PLoS Genetics  
and Jun Zhao in the UCSD Moores Cancer Center Transgenic Mouse Shared Resource for assistance in creating genome-edited mice; Wilson Clements and David Traver for zebrafish embryos, ISH protocols and  ...  Acknowledgments We thank Amanda Roberts in the La Jolla Interdisciplinary Neuroscience Behavior Core at the Scripps Research Institute for consultation and assistance with behavioral assays; Ella Kothari  ...  Sliding window analysis of relative constraint across the protein coding sequence showed that the skipped exon encodes the most evolutionarily constrained peptide sequence among Nmf9 homologs and genome  ... 
doi:10.1371/journal.pgen.1005344 pmid:26131556 pmcid:PMC4488434 fatcat:4tgsreatfbbf3fwiccky7nfy7a

Sanger – Dideoxy Chain Termination Sequencing [chapter]

2018 Molecular Life Sciences  
Conventionally, the medium-scale structural unit of a polypeptide chain is referred to as its secondary structure.  ...  The proper function of proteins is critical to life itself. What kinds of structures can a polymer made of amino acids adopt?  ...  This ability to find genes that match in different individuals is important not only for genealogy but for understanding the genes themselves.  ... 
doi:10.1007/978-1-4614-1531-2_100145 fatcat:54afduv5wbghda5nkcytqipgpi

Synthesis of Modified Oligonucleotides [chapter]

Frederick Peter Guengerich
2018 Molecular Life Sciences  
Conventionally, the medium-scale structural unit of a polypeptide chain is referred to as its secondary structure.  ...  The proper function of proteins is critical to life itself. What kinds of structures can a polymer made of amino acids adopt?  ...  This ability to find genes that match in different individuals is important not only for genealogy but for understanding the genes themselves.  ... 
doi:10.1007/978-1-4614-1531-2_255 fatcat:drah2ovdmbffxaxhmweseif6lq

General sessions (1A-01 - 3E-13)

2005 Genes & Genetic Systems  
The numbers of SNPs affecting ORF were about two-fold larger in genes with duplicates compared with those without duplicate genes (singleton genes).  ...  Large-scale analysis of human SNPs with possible effects on gene function Using dbSNP and the gene structure of more than 21,000 human genes that were revealed in the annotation project of human fulllength  ...  fixed region in the replication origin (ori).  ... 
doi:10.1266/ggs.80.444 fatcat:yec7vkgtjrbmllw2jgztcp5u2i
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