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Considerations for Measurement of Embryonic Organ Growth

Stuti Prakash, Bouke A. de Boer, Jaco Hagoort, Quinn D. Gunst, Jan M. Ruijter, Maurice J. B. van den Hoff
<span title="2018-10-05">2018</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/exptvutuuzh4bfup4qm3tcvmaa" style="color: black;">The Anatomical Record</a> </i> &nbsp;
Studies using stereological and cell sorting methods derive averages of morphogenetic parameters for an organ.  ...  Such measurements require sectioning to enable identification of organ borders, tissue components and cell types, three-dimensional (3D)-reconstruction of sections to visualize morphology and a 3D-measurement  ...  Therefore, to study parts of small embryonic organs, sectioning of the tissue and studying the individual sections was, and still is, the technique of choice (Ruijter et al., 2004) .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/ar.23908">doi:10.1002/ar.23908</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30289204">pmid:30289204</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7028151/">pmcid:PMC7028151</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/j2nlugjgdrchjhpsuc7u7unwz4">fatcat:j2nlugjgdrchjhpsuc7u7unwz4</a> </span>
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Thin-plate spline analysis of mandibular morphological changes induced by early class III treatment: a long-term evaluation

L. Franchi, C. Pavoni, S. Cerroni, P. Cozza
<span title="2013-09-13">2013</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/itugoyo7bjbf3hq44i4eswtsdq" style="color: black;">European Journal of Orthodontics</a> </i> &nbsp;
Procrustes average mandibular configurations were subjected to TPS analysis by means of both cross-sectional between-group comparisons at T1 and at T2 and longitudinal within-group comparisons.  ...  LIMITATIOnS: Limitations are related to the small sample size of both treated and control groups and to the retrospective nature of the study.  ...  TPS analysis enables the construction of transformation grids that capture the differences in shape independently from size and are available for visual interpretation.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/ejo/cjt067">doi:10.1093/ejo/cjt067</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/24036058">pmid:24036058</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/7tpnj5pgknczbgfanrbw56qzn4">fatcat:7tpnj5pgknczbgfanrbw56qzn4</a> </span>
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Drosophila Crumbs Is Required to Inhibit Light-Induced Photoreceptor Degeneration

Kevin Johnson, Ferdi Grawe, Nicola Grzeschik, Elisabeth Knust
<span title="">2002</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/waxwzq3cnbet3cmwccpuk4bel4" style="color: black;">Current Biology</a> </i> &nbsp;
Serial cross-sections (Figures 2C tain a proper zonula adherens (ZA), a belt-like adhesive and 2D) and horizontal sections stained with FITC-phalstructure encircling the apex of epithelial cells [9, 10  ...  visualized as a Germany circumferential belt by anti-Armadillo staining ( Figures 1A-1C) .  ...  The morphogenetic phenotype observed in mosaic eyes of 4E and data not shown).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/s0960-9822(02)01180-6">doi:10.1016/s0960-9822(02)01180-6</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/12361571">pmid:12361571</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/to7thfth5zhblirzf2yuz2poge">fatcat:to7thfth5zhblirzf2yuz2poge</a> </span>
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Computational Model for Early Cardiac Looping

Ashok Ramasubramanian, Kimberly S. Latacha, Jessica M. Benjamin, Dmitry A. Voronov, Arvind Ravi, Larry A. Taber
<span title="2006-05-27">2006</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/imwgooosl5b4lgzai3w2my5g5y" style="color: black;">Annals of Biomedical Engineering</a> </i> &nbsp;
The model, taken together with the new experimental data, supports our hypothesis for the mechanisms that drive early looping.  ...  As per our earlier hypothesis for c-looping, actin-based morphogenetic processes (active cell shape change, cytoskeletal contraction, and cell migration) are simulated in specific regions of the model.  ...  Barna Szabo for his helpful suggestions to improve the accuracy of the finite element simulation, Mathieu Rémond and Nandan Nerurkar for help with experimental data collection, and Patrick Alford and Gang  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10439-005-9021-4">doi:10.1007/s10439-005-9021-4</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/16732433">pmid:16732433</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/i57miecmxzbczj3op7zg3dyql4">fatcat:i57miecmxzbczj3op7zg3dyql4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170914003359/https://link.springer.com/content/pdf/10.1007%2Fs10439-006-9152-2.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/60/4d/604d9ce38bbffea6c5955b0a59e750114c4dba96.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10439-005-9021-4"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a>

Computational Model for Early Cardiac Looping

Ashok Ramasubramanian, Kimberly S. Latacha, Jessica M. Benjamin, Dmitry A. Voronov, Arvind Ravi, Larry A. Taber
<span title="2006-07-13">2006</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/imwgooosl5b4lgzai3w2my5g5y" style="color: black;">Annals of Biomedical Engineering</a> </i> &nbsp;
The model, taken together with the new experimental data, supports our hypothesis for the mechanisms that drive early looping.  ...  As per our earlier hypothesis for c-looping, actin-based morphogenetic processes (active cell shape change, cytoskeletal contraction, and cell migration) are simulated in specific regions of the model.  ...  Barna Szabo for his helpful suggestions to improve the accuracy of the finite element simulation, Mathieu Rémond and Nandan Nerurkar for help with experimental data collection, and Patrick Alford and Gang  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10439-006-9152-2">doi:10.1007/s10439-006-9152-2</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/16732433">pmid:16732433</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/7kpwvvioorhdfgaa5z7zcvthxq">fatcat:7kpwvvioorhdfgaa5z7zcvthxq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170914003359/https://link.springer.com/content/pdf/10.1007%2Fs10439-006-9152-2.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/60/4d/604d9ce38bbffea6c5955b0a59e750114c4dba96.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10439-006-9152-2"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a>

Bone morphogenetic protein-7 accelerates fracture healing in osteoporotic rats

AshishD Diwan, Richard Appleyard, Divya Bhargav, ZhiMing Fang, Anthony Leong, Aiqun Wei
<span title="">2013</span> <i title="Medknow"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/cethjhpgvjfcdla27o5zjmawdy" style="color: black;">Indian Journal of Orthopaedics</a> </i> &nbsp;
This study aimed to determine whether a single dose of bone morphogenetic protein-7 (BMP-7) in a collagen/carboxy-methyl cellulose (CMC) composite enhanced fracture healing in an osteoporotic rat model  ...  Callus cross-sectional area, bone mineral density, biomechanical stiffness and maximum torque, radiographic bony union and histological callus maturity were evaluated at each time point.  ...  Cross-sectional area of the fusion mass was calculated.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.4103/0019-5413.121569">doi:10.4103/0019-5413.121569</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/24379457">pmid:24379457</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3868133/">pmcid:PMC3868133</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cmhedjl42bbkvgfrtsw4kwsnfi">fatcat:cmhedjl42bbkvgfrtsw4kwsnfi</a> </span>
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Sustained Release of Bone Morphogenetic Protein-4 in Adult Rabbit Extraocular Muscle Results in Decreased Force and Muscle Size: Potential for Strabismus Treatment

Brian C. Anderson, Mark L. Daniel, Jeffrey D. Kendall, Stephen P. Christiansen, Linda K. McLoon
<span title="2011-06-08">2011</span> <i title="Association for Research in Vision and Ophthalmology (ARVO)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/bktgmrvaorcfle3nbaxcwpsb44" style="color: black;">Investigative Ophthalmology and Visual Science</a> </i> &nbsp;
To assess the effect of a sustained-release preparation of bone morphogenetic protein-4 (BMP-4) on EOM force generation and muscle size. METHODS.  ...  Sustained-release pellets, releasing 500 nanograms/ day of BMP-4 for a maximum of 3 months, were implanted beneath the superior rectus muscle (SR) belly in anesthetized adult rabbits.  ...  These data correlate very well with the reduction in muscle mass and mean myofiber cross-sectional area.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1167/iovs.10-6878">doi:10.1167/iovs.10-6878</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/21357389">pmid:21357389</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3175951/">pmcid:PMC3175951</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/lgc5gznlgbav5aehoacziimrmu">fatcat:lgc5gznlgbav5aehoacziimrmu</a> </span>
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Characterization of Heterotopic Ossification Using Radiographic Imaging: Evidence for a Paradigm Shift

R. Cameron Brownley, Shailesh Agarwal, Shawn Loder, Oluwatobi Eboda, John Li, Joshua Peterson, Charles Hwang, Christopher Breuler, Vesa Kaartinen, Bin Zhou, Yuji Mishina, Benjamin Levi (+1 others)
<span title="2015-11-06">2015</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
Taken together, these data demonstrate the need for a paradigm shift in the evaluation of HO towards microCT as a standard tool for imaging.  ...  Heterotopic ossification (HO) is the growth of extra-skeletal bone which occurs following trauma, burns, and in patients with genetic bone morphogenetic protein (BMP) receptor mutations.  ...  Acknowledgments We would like to thank the center for Molecular Imaging and Amanda Fair at the University of Michigan for the assistance with their imaging equipment.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0141432">doi:10.1371/journal.pone.0141432</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26544555">pmid:26544555</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4636348/">pmcid:PMC4636348</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/gzc5b3zhsvb57iqhfrpxxq44ji">fatcat:gzc5b3zhsvb57iqhfrpxxq44ji</a> </span>
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Four-dimensional realistic modeling of pancreatic organogenesis

Y. Setty, I. R. Cohen, Y. Dor, D. Harel
<span title="2008-12-17">2008</span> <i title="Proceedings of the National Academy of Sciences"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/nvtuoas5pbdsllkntnhizy4f4q" style="color: black;">Proceedings of the National Academy of Sciences of the United States of America</a> </i> &nbsp;
Modeling Approach In the current study, we focused on the development of the pancreas, a compound organ with a unique structure, essential for the exocrine digestion of foodstuffs and for the hormonal  ...  Here, we describe a fully executable, interactive, visual model for 4D simulation of organogenic development using the mouse pancreas as a representative case.  ...  We compared the image against the emerging structure and a cross-section image (Fig. 3 Top) of the simulation, approximately at the same period.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1073/pnas.0808725105">doi:10.1073/pnas.0808725105</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/19091945">pmid:19091945</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2629264/">pmcid:PMC2629264</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/7m52q3q4ibcjppcbf3tq24lwgm">fatcat:7m52q3q4ibcjppcbf3tq24lwgm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20131020134832/http://www.wisdom.weizmann.ac.il/~harel/papers/Pancreas.PNAS.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/bb/a8/bba8a07ffc2b7b1aaa56d54840846c729fdce56d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1073/pnas.0808725105"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629264" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

A potential role for differential contractility in early brain development and evolution

Benjamen A. Filas, Alina Oltean, David C. Beebe, Ruth J. Okamoto, Philip V. Bayly, Larry A. Taber
<span title="2012-03-31">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/7ofs3f2ch5clzlmufw5ukbtcg4" style="color: black;">Biomechanics and Modeling in Mechanobiology</a> </i> &nbsp;
round cross sections of the tubular brain into shapes resembling triangles, diamonds, and narrow slits.  ...  Tissue staining revealed relatively strong concentration of F-actin at vertices of hyper-contracted cross sections, and a finite element model shows that local contraction in these regions can convert  ...  We gratefully acknowledge Zachary Pincus (Yale University) and Ian Duncan (Washington University) for helpful advice in interpreting our experimental data.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10237-012-0389-4">doi:10.1007/s10237-012-0389-4</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22466353">pmid:22466353</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3475747/">pmcid:PMC3475747</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/pdq7vmc3gjfjlfkvimxkkbx7me">fatcat:pdq7vmc3gjfjlfkvimxkkbx7me</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20191201124419/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3475747&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/a7/0a/a70abbc2291e9a41ce3cd31f8127145a17ed0432.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10237-012-0389-4"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475747" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

The Classic: Bone Morphogenetic Protein

Marshall R. Urist, Basil S. Strates
<span title="2009-09-01">2009</span> <i title="Ovid Technologies (Wolters Kluwer Health)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/lzfv534ahfcedh4w6sklgjsxvm" style="color: black;">Clinical Orthopaedics and Related Research</a> </i> &nbsp;
Molson for electron micrographs.  ...  Thus, data obtained from glutaraldehyde cross-linked matrix, like data obtained from dinitrophenylated matrix, suggest that the bone morphogenetic activity depends on the undenatured native protein structure  ...  In cross section, because of interfibrillar space, at least a third of matrix domain is available for occupancy by ground substance including proteoglycans, shown in Figs. 1 to 3.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s11999-009-1068-3">doi:10.1007/s11999-009-1068-3</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/19727989">pmid:19727989</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2772914/">pmcid:PMC2772914</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/aiatwj4idza5nl7i6drasmninm">fatcat:aiatwj4idza5nl7i6drasmninm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171015082422/http://publisher-connector.core.ac.uk/resourcesync/data/Springer-OA/pdf/837/aHR0cDovL2xpbmsuc3ByaW5nZXIuY29tLzEwLjEwMDcvczExOTk5LTAwOS0xMDY4LTMucGRm.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/62/45/6245b3d5c56b2ba5eaa354eeeb24ecaa84d29de8.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s11999-009-1068-3"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772914" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Morphogenetic processes as data: Quantitative structure in the Drosophila eye imaginal disc [article]

Bradly Alicea, Thomas E Portegys, Diana Gordon, Richard Gordon
<span title="2018-08-19">2018</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
We approach this by addressing three computational hypotheses, and provide a publicly-available repository containing data and images for further analysis.  ...  In the conclusion, we discuss the implications of our approach and findings for developmental complexity and biological theory.  ...  Acknowledgements We would like to highlight the contributions of Tanya Wolff and Kyle Harrington for their previous analytical efforts. Supplemental Files Supplemental File 1.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/395640">doi:10.1101/395640</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/4lfj4td6w5guva45tlqbgw3dam">fatcat:4lfj4td6w5guva45tlqbgw3dam</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190430171748/https://www.biorxiv.org/content/biorxiv/early/2018/10/02/395640.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/10/c1/10c18474b9925468b1ac385065024edc9cd9e8b3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/395640"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

The role of mechanical forces in the torsional component of cardiac looping

Larry A. Taber, Dmitry A. Voronov, Ashok Ramasubramanian
<span title="">2010</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hs2remnzfbfmnf33cof2z4ajhi" style="color: black;">Annals of the New York Academy of Sciences</a> </i> &nbsp;
For each perturbation, our models predict the correct qualitative response of the heart, supporting our hypothesis.  ...  These studies provide new insight into the mechanical mechanisms that drive and regulate cardiac looping.  ...  Acknowledgments This research was supported by grants R01 GM075200 and R01 HL083393 (LAT) from the National Institutes of Health. This support is gratefully acknowledged.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/j.1749-6632.2009.05089.x">doi:10.1111/j.1749-6632.2009.05089.x</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/20201892">pmid:20201892</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2837544/">pmcid:PMC2837544</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/lrus27cyujaj7dfuiluwybkbt4">fatcat:lrus27cyujaj7dfuiluwybkbt4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200211140447/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC2837544&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/49/8c/498ce08a269c363a6523aab9e4f9688937f8bcc4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/j.1749-6632.2009.05089.x"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837544" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Building a better infarct: Modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction

Andrew P. Voorhees, Kristine Y. DeLeon-Pennell, Yonggang Ma, Ganesh V. Halade, Andriy Yabluchanskiy, Rugmani Padmanabhan Iyer, Elizabeth Flynn, Courtney A. Cates, Merry L. Lindsey, Hai-Chao Han
<span title="">2015</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/35q5fuyvlvgejbjueqmd3l6pky" style="color: black;">Journal of Molecular and Cellular Cardiology</a> </i> &nbsp;
The aim of this study was to determine the mechanisms whereby MMP-9 deletion alters collagen network composition and assembly in the LV post-MI to modulate the mechanical properties of myocardial scar  ...  We conclude that MMP-9 deletion increases infarct stiffness and prevents LV dilation by reducing collagen degradation and facilitating collagen assembly and cross-linking through preservation of the fibronectin  ...  Acknowledgments This work was supported by the National Heart, Lung, and Blood Institute [HHSN 268201000036C (N01-HV-00244)] for the San Antonio Cardiovascular Proteomics Center.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.yjmcc.2015.06.006">doi:10.1016/j.yjmcc.2015.06.006</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26080361">pmid:26080361</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4530076/">pmcid:PMC4530076</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ey66vqhss5eybinueqpf4h4jzu">fatcat:ey66vqhss5eybinueqpf4h4jzu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200211144542/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4530076&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/82/07/8207dae6b6b41e0cacd7c9500695596c3162e9dc.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.yjmcc.2015.06.006"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530076" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

On Modeling Morphogenesis of the Looping Heart Following Mechanical Perturbations

Ashok Ramasubramanian, Nandan L. Nerurkar, Kate H. Achtien, Benjamen A. Filas, Dmitry A. Voronov, Larry A. Taber
<span title="">2008</span> <i title="ASME International"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hx7br47qgrdrfmkyfi2aj5tj2e" style="color: black;">Journal of Biomechanical Engineering</a> </i> &nbsp;
Finally, a two-dimensional model of the HT cross section is used to study a feedback mechanism for stress-based regulation of looping.  ...  Here, we present new experimental data and finite element models to help define these mechanisms for the torsional component of c-looping.  ...  "c… Two-dimensional "cross-sectional… model for cardiac rotation.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1115/1.2978990">doi:10.1115/1.2978990</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/19045547">pmid:19045547</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2679589/">pmcid:PMC2679589</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/g5vntht6grfydkeamwtavgpzrq">fatcat:g5vntht6grfydkeamwtavgpzrq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170809010514/http://www.engineering.union.edu/~ramasuba/Ashok_ASME_belpaper.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/8f/48/8f480668cd1aac530d2009aca6c8798276873e95.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1115/1.2978990"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679589" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>
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