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Virus Variation Resource – improved response to emergent viral outbreaks
2016
Nucleic Acids Research
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The resource is located at http://www.ncbi.nlm.nih.gov/genome/ viruses/variation/ and includes modules for seven viral groups: influenza virus, Dengue virus, West Nile virus, Ebolavirus, MERS coronavirus ...
The Virus Variation Resource is a value-added viral sequence data resource hosted by the National Center for Biotechnology Information. ...
to quickly provide new modules in response to emerging outbreaks and associated nucleotide sequencing efforts. ...
doi:10.1093/nar/gkw1065
pmid:27899678
pmcid:PMC5210549
fatcat:rmk3lbtajzed3a3nqyfz2eh3by
Local, national, and regional viral haemorrhagic fever pandemic potential in Africa: a multistage analysis
2017
The Lancet
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viral haemorrhagic fevers in Africa, Crimean-Congo haemorrhagic fever, Ebola virus disease, Lassa fever, and Marburg virus disease. ...
Predicting when and where pathogens will emerge is difficult, yet, as shown by the recent Ebola and Zika epidemics, effective and timely responses are key. ...
This work was funded by a grant from The Paul G Allen Ebola Program (grant 11878) to SIH, which also provided funding for DMP, AD, and CM. ...
doi:10.1016/s0140-6736(17)32092-5
pmid:29031848
pmcid:PMC5735217
fatcat:2dd7o7y53na3rk5gtzucjasjrq
Perspectives on West Africa Ebola Virus Disease Outbreak, 2013–2016
2016
Emerging Infectious Diseases
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The magnitude of the outbreak was not attributable to a substantial change of the virus. ...
Continued efforts during the outbreak and in preparation for future outbreak response should involve identifying the reservoir, improving in-country detection and response capacity, conducting survivor ...
We also acknowledge and commend the international response to the EVD outbreak in West Africa and thank the other members of CDC's Viral Special Pathogens Branch, Division of High-Consequence Pathogens ...
doi:10.3201/eid2206.160021
pmid:27070842
pmcid:PMC4880067
fatcat:t4wgfa2afzbtnoieoda5lg7wpq
Emerging Viral Diseases: Confronting Threats with New Technologies
2014
Science Translational Medicine
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Here too, research advances have greatly improved responses to emerging viruses. ...
Real-time reverse transcription PCR, a quantitative RNA-based technology, has been developed and deployed in outbreaks, including Ebola virus disease outbreaks in Africa Technology
Application to emerging ...
doi:10.1126/scitranslmed.3009872
pmid:25210060
fatcat:mhzauowapfchdaxlnzscnb2may
Genomic Signatures of Emerging Viruses: A New Era of Systems Epidemiology
2016
Cell Host and Microbe
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As genomic technologies become more accessible, these methods will redefine how emerging viruses are studied and outbreaks are contained. ...
Here we review the existing and emerging genomic technologies that are enabling systems epidemiology and systems virology and making it possible to respond rapidly to emerging viruses such as Zika. ...
approaches to rapidly facilitate a more comprehensive understanding of emergent viruses and the host response to the pathogen. ...
doi:10.1016/j.chom.2016.04.016
pmid:27173929
pmcid:PMC7104983
fatcat:qysjwtkef5gujiliuc5t266o64
One Health proof of concept: Bringing a transdisciplinary approach to surveillance for zoonotic viruses at the human-wild animal interface
2017
Preventive Veterinary Medicine
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, improving our understanding of viral disease spillover from wildlife and implementing strategies for preventing and controlling emerging disease threats. ...
Such an approach presents important opportunities to reduce the impact of disease emergence events and also to mitigate future emergence through improved cross-sectoral coordination. ...
The contents are the responsibility of the PREDICT Consortium and do not necessarily reflect the views of USAID or the United States Government. ...
doi:10.1016/j.prevetmed.2016.11.023
pmid:28034593
pmcid:PMC7132382
fatcat:7xd5ov3snbe53p77c2gkaimzxi
Systems approaches to coronavirus pathogenesis
2014
Current Opinion in Virology
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As emergent viruses may cause episodic outbreaks of disease over time, human samples are limited. ...
The advent of systems genetic and biology resources provide new opportunities for deconvoluting the complex genetic interactions and expression networks that regulate pathogenic or protective host response ...
Acknowledgments We wish to acknowledge SP and RG for assistance with figures. ...
doi:10.1016/j.coviro.2014.04.007
pmid:24842079
pmcid:PMC4076299
fatcat:q6ozyszhyvgmbbyehktwb2cgua
Harnessing DNA Synthesis to Develop Rapid Responses to Emerging and Pandemic Pathogens
2011
Journal of Pathogens
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Given the interconnected nature of our world today, emerging pathogens and pandemic outbreaks are an ever-growing threat to the health and economic stability of the global community. ...
This is evident by the recent 2009 Influenza A (H1N1) pandemic, the SARS outbreak, as well as the ever-present threat of global bioterrorism. ...
Acknowledgments The authors would like to thank JAMC for his support in preparing this publication. Dr. ...
doi:10.4061/2011/765763
pmid:23533775
pmcid:PMC3595711
fatcat:ue5fdvxwtzegxnclajftbbgy2e
Open Sources and Crowdsourcing for Combating Emerging and Reemerging Infectious Diseases
2016
Infectious Diseases and Translational Medicine
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This process can often delay understanding the pathogenic strain responsible for an outbreak, which in turn delays the development of prevention and control strategies. ...
Emerging infectious diseases (EIDs) could quickly cross national borders as a result of air travel, and spread disaster and panic globally within months or even days. ...
A resource of viral genome information [25] is maintained at the NCBI, including genome sequences, variations, and analyzing tools (http://www.ncbi.nlm.nih. gov/genome/viruses/). ...
doi:10.11979/idtm.201603003
doaj:62cbb22d791947709d8226d84bfe36aa
fatcat:ekypiu3g5zbfjbhz5hccygglam
Enlightenment from the COVID-19 Pandemic: The Roles of Environmental Factors in Future Public Health Emergency Response
2021
Engineering
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, and after the responses to such emergencies. ...
To improve countries' capability to respond to public health emergencies associated with viral infections such as the COVID-19 pandemic, a number of environmental factors should be considered before, during ...
of viral outbreaks so as to improve the early-warning capabilities of PHERSs. ...
doi:10.1016/j.eng.2020.12.019
pmid:33747606
pmcid:PMC7955573
fatcat:uuqwxq6brjartlzjnbjuwmgte4
Emerging and Re-emerging Infectious Diseases
[chapter]
2009
National Institute of Allergy and Infectious Diseases, NIH
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)
Variola major (smallpox) and other related pox viruses
Francisella tularensis (tularemia)
Viral hemorrhagic fevers:
Arenaviruses
LCM, Junin virus, Machupo virus, Guanarito virus
Lassa fever
Bunyaviruses ...
Research Plans and Priorities In response to the threat of emerging and re-emerging infectious diseases, NIAID has developed a strategy for addressing these issues through targeted research and training ...
doi:10.1007/978-1-60327-297-1_4
fatcat:rqrcbof3nrg5nkjwxj7gj5zade
International Conference on Emerging Infectious Diseases in the Pacific Rim, Bangkok, Thailand
1997
Emerging Infectious Diseases
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Lessons learned from outbreaks in the last 15 years contribute to developing strategies for the mobilization of resources to respond rapidly to emerging foodborne microbial hazards. ...
genetic variability, and genomic analysis; vaccine development; and improved vector control and fundamental strengthening of public health practices to address emerging infectious diseases including improved ...
A session on viral hemorrhagic fevers reviewed recent Ebola virus outbreaks and the ...
doi:10.3201/eid0302.970229
fatcat:bbx4f5agpvhtbmtwl2nqyzj3bq
The Origins and Future of Sentinel: An Early-Warning System for Pandemic Preemption and Response
2021
Viruses
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improve pandemic preparedness and response anywhere in the world. ...
As we delved further, we conjectured that the "emerging" nature of recently discovered diseases like Lassa fever is related to a newfound capacity for detection, rather than a novel viral presence, and ...
Branco is co-founder and managing director of Zalgen Labs, a biotechnology company developing countermeasures to emerging viruses. Kristian G. ...
doi:10.3390/v13081605
pmid:34452470
pmcid:PMC8402630
fatcat:xjbx5qswg5bfhgafwjumo36cbe
Bat-borne virus diversity, spillover and emergence
2020
Nature Reviews Microbiology
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to anticipate and prepare for the next viral outbreak. ...
response and prevention efforts. ...
K.J.O. is supported by the USAID Emerging Pandemic Threats PREDICT program, NIH/NIAID award R01AI110964 and a US Defense Threat Reduction Agency award HDTRA11710064. ...
doi:10.1038/s41579-020-0394-z
pmid:32528128
pmcid:PMC7289071
fatcat:xnoiezq6hrhe5l6fnz7p3zjwau
Pathogenesis of Uveitis in Ebola Virus Disease Survivors: Evolving Understanding from Outbreaks to Animal Models
2020
Microorganisms
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Ebola virus disease (EVD) and emerging infectious disease threats continue to threaten life, prosperity and global health security. ...
Moreover, in vitro models of Ebola virus have shown permissiveness in retinal pigment epithelial cells, potentially contributing to viral persistence. ...
The funders had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. ...
doi:10.3390/microorganisms8040594
pmid:32325950
pmcid:PMC7232169
fatcat:oscn6seynvg5fgmvmdbzq3o7ze
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