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Vessel Segmentation for Ablation Treatment Planning and Simulation [chapter]

Tuomas Alhonnoro, Mika Pollari, Mikko Lilja, Ronan Flanagan, Bernhard Kainz, Judith Muehl, Ursula Mayrhauser, Horst Portugaller, Philipp Stiegler, Karlheinz Tscheliessnigg
2010 Lecture Notes in Computer Science  
In this paper, a novel segmentation method for liver vasculature is presented, intended for numerical simulation of radio frequency ablation (RFA).  ...  The results showed improved accuracy over common approaches and illustrated the method's suitability for simulation purposes.  ...  Conclusion We have demonstrated a new, efficient and robust hybrid vessel segmentation for RFA ablation simulation.  ... 
doi:10.1007/978-3-642-15705-9_6 fatcat:l7delph6n5agfmpu3w4xunysce

Go-Smart: Web-based Computational Modeling of Minimally Invasive Cancer Treatments [article]

Phil Weir, Dominic Reuter, Roland Ellerweg, Tuomas Alhonnoro, Mika Pollari, Philip Voglreiter, Panchatcharam Mariappan, Ronan Flanagan, Chang Sub Park, Stephen Payne, Elmar Staerk, Peter Voigt (+2 others)
2015 arXiv   pre-print
Go-Smart includes evaluation techniques for comparing simulated treatment with real ablation lesions segmented from follow-up scans.  ...  This model is used to compare patient-specific treatment plans and device performance via built-in simulation tools.  ...  authors gratefully acknowledge the significant contribution to this project made by our clinical partners at Leipzig University, Medical University of Graz, Radboud University Medical Centre Nijmegen and  ... 
arXiv:1511.03418v1 fatcat:jm34u6anjrcybchkcpvk4q4kqq

Technologies for Guidance of Radiofrequency Ablation in the Multimodality Interventional Suite of the Future

Bradford J. Wood, Julia K. Locklin, Anand Viswanathan, Jochen Kruecker, Dieter Haemmerich, Juan Cebral, Ariela Sofer, Ruida Cheng, Evan McCreedy, Kevin Cleary, Matthew J. McAuliffe, Neil Glossop (+1 others)
2007 Journal of Vascular and Interventional Radiology  
The integration of treatment planning with computed tomography robot systems or electromagnetic needle-tip tracking allows for seamless, iterative, "see-and-treat," patient-specific tumor ablation.  ...  Such automation, navigation, and visualization tools could eventually optimize radiofrequency ablation and other needle-based ablation procedures and decrease variability among operators, thus facilitating  ...  Semiautomated simulation and treatment planning may better plan RFA with semiautomatic segmentation of vessels, organs, and tumor, followed by virtual needle placement.  ... 
doi:10.1016/j.jvir.2006.10.013 pmid:17296700 pmcid:PMC2555973 fatcat:b56abhs6lfco7i72ods4jsziiy

Thermal modelling using discrete vasculature for thermal therapy: A review

H. Petra Kok, Johanna Gellermann, Cornelis A.T. van den Berg, Paul R. Stauffer, Jeffrey W. Hand, Johannes Crezee
2013 International Journal of Hyperthermia  
This review describes the progress in thermal modelling with discrete vasculature for the purpose of hyperthermia treatment planning and thermal ablation.  ...  Reliable temperature information during clinical hyperthermia and thermal ablation is essential for adequate treatment control, but conventional temperature measurements do not provide 3D temperature information  ...  purposes and thermal ablation planning, then progressing to more sophisticated vascular models suitable for clinical hyperthermia treatment planning.  ... 
doi:10.3109/02656736.2013.801521 pmid:23738700 pmcid:PMC3684078 fatcat:tlm3u4jwibbpbn4rt6cn66lfmy

RFA Guardian: Comprehensive Simulation of Radiofrequency Ablation Treatment of Liver Tumors

Philip Voglreiter, Panchatcharam Mariappan, Mika Pollari, Ronan Flanagan, Roberto Blanco Sequeiros, Rupert Horst Portugaller, Jurgen Fütterer, Dieter Schmalstieg, Marina Kolesnik, Michael Moche
2018 Scientific Reports  
These include pre-interventional planning, sampling of the parameter space for uncertainty estimation, treatment evaluation and, in the worst case, failure analysis.  ...  The RFA Guardian is the first of its kind that exhibits sufficient performance for simulating treatment outcomes during the intervention.  ...  Acknowledgements This work was co-funded by the European Union in the projects ClinicIMPPACT (grant no. 610886) and GoSmart (grant no. 600641).  ... 
doi:10.1038/s41598-017-18899-2 pmid:29335429 pmcid:PMC5768804 fatcat:heftmcc42jhgbprnstzwvbb4ae

Pre- and Intra-operative Planning and Simulation of Percutaneous Tumor Ablation [chapter]

Torsten Butz, Simon K. Warfield, Kemal Tuncali, Stuart G. Silverman, Eric van Sonnenberg, Ferenc A. Jolesz, Ron Kikinis
2000 Lecture Notes in Computer Science  
We developed a software tool for pre-operative simulation and planning, and intra-operative guidance, of minimally invasive tumor ablation, including radiofrequency-, laser-and cryo-therapy.  ...  This tool provides a pre-and intra-operative optimization of the treatment plan, in order to avoid dangerous probe trajectories, undertreatment of the tumor, and excessive ablation of healthy tissues.  ...  Simulating the Treatment Plan In Figure 3a and b, we simulate the setup that was chosen by the radiologists.  ... 
doi:10.1007/978-3-540-40899-4_32 fatcat:d6aoziqjqze2heugc3mk2d2zom

Software-based planning of ultrasound and CT-guided percutaneous radiofrequency ablation in hepatic tumors

M. J. van Amerongen, P. Mariappan, P. Voglreiter, R. Flanagan, S. F. M. Jenniskens, M. Pollari, M. Kolesnik, M. Moche, J. J. Fütterer
2021 International Journal of Computer Assisted Radiology and Surgery  
After visual assessment, 9 incomplete ablations were observed, of which 4 true positives and 5 false positives for the detection of an incomplete ablation.  ...  Objectives Radiofrequency ablation (RFA) can be associated with local recurrences in the treatment of liver tumors.  ...  The steps necessary for treatment planning in the RFA Guardian are described elsewhere [13] .  ... 
doi:10.1007/s11548-021-02394-1 pmid:33974224 fatcat:whgc42pwdvgdnpkwfkvvs2p7fq

Intervention Planning of Hepatocellular Carcinoma Radio-Frequency Ablations [chapter]

Bernhard Kerbl, Philip Voglreiter, Rostislav Khlebnikov, Dieter Schmalstieg, Daniel Seider, Michael Moche, Philipp Stiegler, Rupert H. Portugaller, Bernhard Kainz
2013 Lecture Notes in Computer Science  
We present a software solution for planning and simulating radio-frequency ablation (RFA) treatment for patients suffering from hepatocellular carcinoma.  ...  Data collected during simulations allow for detailed illustration of expected effectiveness and progress of heat-induced necrosis over time.  ...  This work was funded by the European Union in FP7 VPH initiative under contract number 223877 (IMPPACT) and by the Austrian Science Fund (FWF): P23329.  ... 
doi:10.1007/978-3-642-38079-2_2 fatcat:d5dzphk6nffhffmuhalaiq2l6a

HIFUpm: a Visual Environment to Plan and Monitor High Intensity Focused Ultrasound Treatments

Daniela Modena, Davide Bassano, Aaldert Elevelt, Marco Baragona, Peter A. J. Hilbers, Michel A. Westenberg
2019 Eurographics Workshop on Visual Computing for Biomedicine  
For this reason, a correct therapy planning and monitoring in HIFU treatments remains a challenge.  ...  We illustrate the use of HIFUpm for an ablative treatment of an osteoid osteoma. This use case demonstrates that HIFUpm provides a flexible visual environment to plan and monitor HIFU procedures.  ...  Acknowledgments The authors wish to thank Zoi Tokoutsi for the inspiring discussion about the model order reduction methods.  ... 
doi:10.2312/vcbm.20191246 dblp:conf/vcbm/ModenaBEBHW19 fatcat:ltpoghmlazc2zodclnh5ojxgue

A novel tool for monitoring and assessing the outcome of thermal ablations of hepatic lesions

Georg Hille, Felicitas Brokmann, Bennet Hensen, Julian Alpers, Frank Wacker, Sylvia Saalfeld
2021 Current Directions in Biomedical Engineering  
For this purpose, simulated 3D+t temperature maps of the ablation progress are combined with liver MR imaging, as well as corresponding segmentations of the lesion and other relevant anatomical structures  ...  and detailed feedback to assess the treatment result.  ...  Author Statement Research funding: The work of this paper is funded by the Federal Ministry of Education and Research within the Forschungscampus STIMULATE under grant number '13GW0095A' and '13GW0095C  ... 
doi:10.1515/cdbme-2021-1016 fatcat:5vdfiabkdngazooumxr3yygqaq

Image-based 3D modeling and validation of radiofrequency interstitial tumor ablation using a tissue-mimicking breast phantom

Zhigang Wang, Isshaa Aarya, Mariana Gueorguieva, Dun Liu, Hongyan Luo, Luigi Manfredi, Lijun Wang, Donald McLean, Stuart Coleman, Stuart Brown, Alfred Cuschieri
2012 International Journal of Computer Assisted Radiology and Surgery  
The ablation volumes achieved both in the FEM simulation and the experimental test were equivalent, indicating that patientspecific models can be implemented for pre-treatment planning of solid tumor ablation  ...  Patientspecific image-based 3D modeling for thermal ablation simulation was developed to optimize treatment protocols that improve treatment efficacy.  ...  Acknowledgments This article presents independent research partially commissioned by the National Institute for Health Research (NIHR) under Invention for Innovation (i4i) Programme.  ... 
doi:10.1007/s11548-012-0769-3 pmid:22688380 fatcat:3f4k6pikfng5dj3fiqrwdrtoxm

Image-based multi-scale modelling and validation of radio-frequency ablation in liver tumours

S. Payne, R. Flanagan, M. Pollari, T. Alhonnoro, C. Bost, D. O'Neill, T. Peng, P. Stiegler
2011 Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences  
In this paper, we outline our work towards developing a simulation tool kit that could be used both to optimize treatment protocols in advance and to train the less-experienced clinicians for RFA treatment  ...  We show how simulations of ablations in two pigs, based on individualized imaging data, compare directly with experimentally measured lesion sizes and discuss the likely sources of error and routes towards  ...  density by the end of the image-based multi-scale physiological planning for ablation cancer treatment (IMPPACT) project.  ... 
doi:10.1098/rsta.2011.0240 pmid:21969674 fatcat:4wyfa5ly6nhnlayef3mgcb3bwa

Careful treatment planning enables safe ablation of liver tumors adjacent to major blood vessels by percutaneous irreversible electroporation (IRE)

Bor Kos, Peter Voigt, Damijan Miklavcic, Michael Moche
2015 Radiology and Oncology  
Treatment planning using accurate computer models was recognized as important for electrochemotherapy and irreversible electroporation.  ...  We present a method for treatment planning of IRE which takes the influence of blood vessels on the electric field into account; this is illustrated on a treatment of 48-year-old patient with a metastasis  ...  Acknowledgements The work was performed in the scope of The European Associated Laboratory entitled Pulsed Electric Fields Applications in Biology and Medicine (LEA-EBAM). The research was sup-  ... 
doi:10.1515/raon-2015-0031 pmid:26401128 pmcid:PMC4577219 fatcat:5gwi27bhf5getous7nkyyphq6u

Planning Irreversible Electroporation in the Porcine Kidney: Are Numerical Simulations Reliable for Predicting Empiric Ablation Outcomes?

Thomas Wimmer, Govindarajan Srimathveeravalli, Narendra Gutta, Paula C. Ezell, Sebastien Monette, Majid Maybody, Joseph P. Erinjery, Jeremy C. Durack, Jonathan A. Coleman, Stephen B. Solomon
2014 Cardiovascular and Interventional Radiology  
Purpose-Numerical simulations are used for treatment planning in clinical applications of irreversible electroporation (IRE) to determine ablation size and shape.  ...  To assess the reliability of simulations for treatment planning, we compared simulation results with empiric outcomes of renal IRE using computed tomography (CT) and histology in an animal model.  ...  Solomon received an unrestricted grant and equipment from Angiodynamics Inc. S. B. Solomon is also a consultant for Covidien and received a grant from GE Healthcare.  ... 
doi:10.1007/s00270-014-0905-2 pmid:24831827 pmcid:PMC5497497 fatcat:fiatqjfciffajngitsmnd76ifm

Planning of anatomical resections and in situ ablations in oncologic liver surgery

A Littmann, A Schenk, B Preim, G Prause, K Lehmann, A Roggan, H.-O Peitgen
2003 Excerpta Medica: International Congress Series  
We describe a software system that helps both to determine anatomically correct and surgically realizable resection territories and to plan minimally invasive interventions for cases, that are impracticable  ...  for surgery.  ...  The spatial relations between pathological and vital structures are essential for estimating the risks of minimally invasive and surgical treatment.  ... 
doi:10.1016/s0531-5131(03)00319-4 fatcat:ijidd746lrh57nrbnrvh4avpue
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