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Vertebral landmarks for the identification of spinal cord segments in the mouse
2013
NeuroImage
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Accurate identification of spinal cord segments in relation to vertebral landmarks is essential to surgery aimed at experimental spinal cord injury. ...
We have analyzed a complete series of high-resolution magnetic resonance (MR) images from the mouse spine in order to delineate the boundaries of spinal cord segments in relation to vertebral landmarks ...
This work was supported in part by funding from the Queensland Nuclear Magnetic Resonance Network and from an Enabling Grant from the National Health and Medical Research Council of Australia (NHMRC) to ...
doi:10.1016/j.neuroimage.2012.11.048
pmid:23246856
fatcat:tpm65m45knhgtpo5uxe2ykug64
Sacral Spinal Cord Transection and Isolated Sacral Cord Preparation to Study Chronic Spinal Cord Injury in Adult Mice
2018
Bio-protocol
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of the spinal cord. ...
We generated a mouse model of chronic spinal cord injury that reliably reproduces spasticity observed after SCI, while at the same time allows study of motor impairments in vivo and in an in vitro preparation ...
The authors declare that they have no conflicts or competing interests. ...
doi:10.21769/bioprotoc.2784
pmid:29795778
pmcid:PMC5961933
fatcat:rpknmzg6vfhhldfnkh2wa4hqkq
A novel approach for assigning levels to monkey and human lumbosacral spinal cord based on ventral horn morphology
2017
PLoS ONE
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Acknowledgments The authors would like to thank Lauren Broom for proofreading the manuscript.
Author Contributions ...
Results
Identification of rostral and caudal lumbosacral landmarks in monkey and human spinal cord In monkeys, retrogradely (CTb) labeled motoneurons innervating the iliopsoas muscle formed the most ...
Fig 1 . 1 Identification of rostral and caudal landmarks in the lumbosacral enlargement in rhesus monkey and humans. ...
doi:10.1371/journal.pone.0177243
pmid:28542213
pmcid:PMC5443490
fatcat:3laqr3zngfattdhonqb3pljjfa
Identification of Apical Vertebra for Grading of Idiopathic Scoliosis using Image Processing
2011
Journal of digital imaging
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Precise measurement of apical vertebral rotation in terms of grading is most valuable for the determination of reference value in normal and pathological conditions for better understanding of scoliosis ...
Scoliosis is a 3-D deformity of spinal column, characterized by both lateral curvature and vertebral rotation. ...
In case of pedicle screw misplacement that incur risks of spinal cord injury. ...
doi:10.1007/s10278-011-9394-x
pmid:21725622
pmcid:PMC3264723
fatcat:5skbsv7tvvhvfbmzutzscezz3y
Spinal vertebrae localization and analysis on disproportionality in curvature using radiography—a comprehensive review
2021
EURASIP Journal on Image and Video Processing
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of curvature deformity of the vertebrae in the spinal cord. ...
The spinal cord assists the overall communication network of the human anatomy through the brain. ...
I would also like to acknowledge the support provided by my university. ...
doi:10.1186/s13640-021-00563-5
fatcat:khzxpnubxjdnto4zdcpbxqxvnu
Magnetic resonance microimaging of the spinal cord in the SOD1 mouse model of amyotrophic lateral sclerosis detects motor nerve root degeneration
2011
NeuroImage
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These results demonstrate the usefulness of MRM in visualising the ultrastructure of the mouse spinal cord. ...
MRM signal intensity was increased exclusively in the ventral motor nerve roots of the lumbar spinal cord of ALS-affected SOD1 mice compared to wildtype littermates. ...
Acknowledgements Funding provided by the Ross Maclean Fellowship, Peter Goodenough Bequest and the Queensland Nuclear Magnetic Resonance Network. Jane Ellis for assistance with histology.
References ...
doi:10.1016/j.neuroimage.2011.06.003
pmid:21689764
fatcat:75a3z6lklrhw3pfsoovrouf7du
Transmitter-phenotypes of commissural interneurons in the lumbar spinal cord of newborn mice
2009
Journal of Comparative Neurology
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Our results suggest that glycinergic, GABAergic, and glutamatergic CINs are the principal CIN phenotypes in the CPG region of the lumbar spinal cord in the newborn mouse. ...
In this study we describe the relative proportions and anatomical locations of putative inhibitory and excitatory CINs in the lumbar spinal cord of newborn mice. ...
ACKNOWLEDGMENTS We thank Mette Kirkegaard for comments on a previous version of the article, and Lovisa Kä llman and Anna Eriksson for caretaking and breeding of the different transgenic lines used in ...
doi:10.1002/cne.22144
pmid:19731323
fatcat:eutp5jmpzjc3hmqxql2axtw33a
The transneuronal spread phenotype of herpes simplex virus type 1 infection of the mouse hind footpad
1997
Journal of Virology
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The mouse hind footpad inoculation model has served as a standard laboratory system for the study of the neuropathogenesis of herpes simplex virus type 1 (HSV-1) infection. ...
regions of the spinal cord on days 5 and 6 p.i. ...
in the nucleus proprius and the nucleus dorsalis regions of the spinal cord gray matter at the segment of entry and two to three segments rostral and caudal to the entry segment and (ii) the long fibers ...
pmid:9032380
pmcid:PMC191353
fatcat:6mgxbodq6vebtddtxfol7c62ay
The transneuronal spread phenotype of herpes simplex virus type 1 infection of the mouse hind footpad
1997
Journal of Virology
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The mouse hind footpad inoculation model has served as a standard laboratory system for the study of the neuropathogenesis of herpes simplex virus type 1 (HSV-1) infection. ...
regions of the spinal cord on days 5 and 6 p.i. ...
in the nucleus proprius and the nucleus dorsalis regions of the spinal cord gray matter at the segment of entry and two to three segments rostral and caudal to the entry segment and (ii) the long fibers ...
doi:10.1128/jvi.71.3.2425-2435.1997
fatcat:ugijjf64hfhyhpoziuryvqvfyy
Segmental pattern of development of the hindbrain and spinal cord of the zebrafish embryo
1988
Development
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Young neurones within both the hindbrain and spinal cord were identified in live embryos using Nomarski optics, and histochemically by labelling for acetylcholinesterase activity and expression of an antigen ...
A continuous longitudinal column of developing neurones appears in the spinal cord, whereas an alternating series of large and small clusters of neurones is present in the hindbrain. ...
The work was supported by NIH grants NS17963, NS21132, NS01O65, GMO7257, GMO7413 and HD22486. ...
pmid:3197633
fatcat:rxflafqse5aojaxmwai2xjqtyy
Characterization of A11 Neurons Projecting to the Spinal Cord of Mice
2014
PLoS ONE
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The hypothalamic A11 region has been identified in several species including rats, mice, cats, monkeys, zebrafish, and humans as the primary source of descending dopamine (DA) to the spinal cord. ...
It has been implicated in the control of pain, modulation of the spinal locomotor network, restless leg syndrome, and cataplexy, yet the A11 cell group remains an understudied dopaminergic (DAergic) nucleus ...
Example of retrograde labelling in the A11 caudal area following FluoroGold (FG) injections into the lumbar spinal cord between lumbar vertebral segments L4 and L5. ...
doi:10.1371/journal.pone.0109636
pmid:25343491
pmcid:PMC4208762
fatcat:6mwsnztvbnhpxcafis4dufntxq
Complementary expression of transmembrane ephrins and their receptors in the mouse spinal cord: a possible role in constraining the orientation of longitudinally projecting axons
2000
Development
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We show here that B-class transmembrane ephrins and their receptors are reciprocally expressed on floor plate cells and longitudinally projecting axons in the mouse spinal cord. ...
In the developing spinal cord, axons project in both the transverse plane, perpendicular to the floor plate, and in the longitudinal plane, parallel to the floor plate. ...
This work was aided by grants from the Christopher Reeve Paralysis Foundation (KBA9701 and KBR1-9904-1) and the Spinal Cord Research Foundation (1877-01) to Z. K. ...
pmid:10704386
fatcat:tgkisuidqnbdbbozy2nidufasy
Chronic in vivo imaging in the mouse spinal cord using an implanted chamber
2012
Nature Methods
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We developed a chronically implanted spinal chamber and surgical procedure suitable for time-lapse in vivo multiphoton microscopy of mouse spinal cord without the need for repeat surgical procedures. ...
Understanding and treatment of spinal cord pathology is limited in part by a lack of longitudinal in vivo imaging strategies at the cellular level. ...
support, and IMRA America, Inc. for the loan of their FCPA μJewel D-400 laser. ...
doi:10.1038/nmeth.1856
pmid:22266542
pmcid:PMC3429123
fatcat:ep6r5zvit5bzdnkk77gixrrrwu
A Spinal Cord Window Chamber Model for In Vivo Longitudinal Multimodal Optical and Acoustic Imaging in a Murine Model
2013
PLoS ONE
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However, longitudinal in vivo imaging of the intact spinal cord in rodent models has been challenging, requiring repeated surgeries to expose the cord for imaging or sacrifice of animals at various time ...
In vivo and direct imaging of the murine spinal cord and its vasculature using multimodal (optical and acoustic) imaging techniques could significantly advance preclinical studies of the spinal cord. ...
The views expressed in this manuscript do not necessarily reflect those of the Ontario Ministry of Health and Long Term Care (OMHLTC). Dr. ...
doi:10.1371/journal.pone.0058081
pmid:23516432
pmcid:PMC3597636
fatcat:6nk45iixebf2fnydg24vtrhaw4
OncoSpineSeg: A Software Tool for a Manual Segmentation of Computed Tomography of the Spine on Cancer Patients
[chapter]
2017
Computed Tomography - Advanced Applications
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This chapter presents the design of a MATLAB-based software for the manual segmentation of the spine. ...
A precise segmentation of the spine is important as a first stage in any automatic diagnosis task. ...
The authors thank Dr. Estanislao Arana for his collaboration. ...
doi:10.5772/intechopen.68552
fatcat:medlsudid5c55lydc6j2kx3en4
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