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Wearable devices that allow continuous monitoring of peripheral oxygen saturation (SpO2), such as the Garmin Fēnix® 5X Plus (GAR), might provide early detection to prevent hypoxia-induced diseases. ... SpO2 was measured with GAR and the medically certified Covidien Nellcor SpO2 monitor (COV) at six time points in 13 healthy lowlanders after a rapid ascent from 1130 m to 4559 m. ... Conflicts of Interest: The authors declare no conflict of interest. ...doi:10.3390/s21196363 pmid:34640680 fatcat:fsocpyvpqrakzpiuvld2guvqlq