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Characterization of the cortical myeloarchitecture with inhomogeneous Magnetization Transfer imaging (ihMT)
2020
NeuroImage
Preserved Fulltext
A recent development of the MT technique, ihMT, has demonstrated greater myelin sensitivity/specificity. ...
While myelin water imaging and ultra-short TE imaging have not yet been implemented to assess cortical myeloarchitecture, magnetization transfer (MT) shows promise. ...
This selectivity was further validated by correlation with histological fluorescence microscopy ( Duhamel et al., 2019 ) . ...
doi:10.1016/j.neuroimage.2020.117442
pmid:33039620
fatcat:ktx4i6irije4bakqknlwbkqdwm
Can MRI measure myelin? Systematic review, qualitative assessment, and meta-analysis of studies validating microstructural imaging with myelin histology
[article]
2020
bioRxiv
pre-print
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single most sensitive strategy to measure myelin with MRI. ...
Non-invasive microstructural magnetic resonance imaging (MRI) holds the potential to expand and translate these insights to basic and clinical human research, but the sensitivity and specificity of different ...
We thank Edgar Liberis for his help with curating the online resource, Thomas Wassenaar for his advice on AMSTAR guidelines and Gunther Helms for his input on the macromolecular pool measure. ...
doi:10.1101/2020.09.08.286518
fatcat:ouwlfl6jtrbbrm6bqayso3uumy
Magnetization Transfer-Mediated MR Fingerprinting
[article]
2021
arXiv
pre-print
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Purpose: Magnetization transfer (MT) and inhomogeneous MT (ihMT) contrasts are used in MRI to provide information about macromolecular tissue content. ...
In particular, MT is sensitive to macromolecules and ihMT appears to be specific to myelinated tissue. ...
INTRODUCTION
Magnetization transfer (MT) and inhomogeneous MT (ihMT) contrasts are used in MRI to provide information about macromolecular tissue content. ...
arXiv:2104.02406v1
fatcat:lh5bbrr4znamvbjzkcuaa5nvey
Mapping the Rest of the Human Connectome: Atlasing the Spinal Cord and Peripheral Nervous System
2020
NeuroImage
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Here we recommend a modification to the definition of the human connectome to include the SC and PNS, and argue for the creation of an inclusive atlas to complement current efforts to map the brain's human ...
However, these efforts are not structured to examine the richness and complexity of the peripheral nervous system (PNS), which arguably forms the (neglected) rest of the connectome. ...
Other techniques which can be leveraged to image myelin include magnetization transfer imaging (MTI) ( Schmierer et al., 2004 ) , quantitative magnetization transfer MRI (qMT-MRI) ( Ou et al., 2009 ) ...
doi:10.1016/j.neuroimage.2020.117478
pmid:33160086
pmcid:PMC8485987
fatcat:nje75t2s4bdrpkqpwtouxu73d4
Referee report. For: Silent myelin-weighted magnetic resonance imaging [version 2; peer review: 2 approved, 2 approved with reservations]
2020
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Inhomogeneous Magnetization Transfer (ihMT) is an emerging, uniquely myelin-specific magnetic resonance imaging (MRI) contrast. ...
Results: We demonstrated that ihMT ratios comparable to existing, acoustically loud, implementations could be obtained with the silent sequence. ...
"This variation can at least in part be attributed to the orientation of the head with the main magnetic field. " and "Despite these shortcomings, we showed a strong effect of angle on inverse ihMTR". ...
doi:10.21956/wellcomeopenres.17734.r39965
fatcat:msbldl3eqjhltmsfbzoq3jpeki