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An exome sequencing pipeline for identifying and genotyping common CNVs associated with disease with application to psoriasis

L. J. M. Coin, D. Cao, J. Ren, X. Zuo, L. Sun, S. Yang, X. Zhang, Y. Cui, Y. Li, X. Jin, J. Wang
2012 Bioinformatics  
Exome sequencing is now widely being applied to case-control cohorts and presents an exciting opportunity to look for common CNVs associated with disease.  ...  This may be partially attributed to the difficulty in accurately genotyping CNVs in large cohorts using array-based technologies.  ...  ACKNOWLEDGEMENT We would to thank Haojing Shao for valuable discussions on Exome Sequence data.  ... 
doi:10.1093/bioinformatics/bts379 pmid:22962454 pmcid:PMC3436806 fatcat:inrtptx7fbhwvgyrfzavcoubje

The next generation of target capture technologies - large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity

Johannes Dapprich, Deborah Ferriola, Kate Mackiewicz, Peter M. Clark, Eric Rappaport, Monica D'Arcy, Ariella Sasson, Xiaowu Gai, Jonathan Schug, Klaus H. Kaestner, Dimitri Monos
2016 BMC Genomics  
Our results show an average depth of coverage of 164X for the entire MHC.  ...  The ability to capture and sequence large contiguous DNA fragments represents a significant advancement towards the comprehensive characterization of complex genomic regions.  ...  Ethics approval and consent to participate Not applicable.  ... 
doi:10.1186/s12864-016-2836-6 pmid:27393338 pmcid:PMC4938946 fatcat:yqwazoghavazhbmeq5yaxpv5iy

Fast sorting for exact OIT of complex scenes

Pyarelal Knowles, Geoff Leach, Fabio Zambetta
2014 The Visual Computer  
In some cases the sorting stage is reduced to no longer be the dominant OIT component.  ...  The sorting stage is a bottleneck for high depth complexity scenes, taking 70-95% of the total time for those investigated.  ...  It and variations capture fragments in sorted order, but render the scene many timesproportional to the captured depth complexity.  ... 
doi:10.1007/s00371-014-0956-z fatcat:5pkn33qy6je7pkya4inqganfbe

Complex formation in proton-hydrogen collisions. II. Isotope effects

Christoph G. Schlier, Ulrike Vix
1987 Chemical Physics  
At collision energies below 1/100 of the well depth the isotope effect disappears, and the complex formation cross section becomes equal to the capture cross section if the target has no (classical) internal  ...  Complex formation cross sections have been determined for many combinations of projectile and target masses, showing that capture behind the centrifugal barrier is a necessary but by no means sufficient  ...  The error of these fits is generally below 1%, but we have used the original values when we make reference to capture cross sections.  ... 
doi:10.1016/0301-0104(87)80149-0 fatcat:ncbwmrzhevbmrjt52pkzprtzoi

Learning to be a depth camera for close-range human capture and interaction

Sean Ryan Fanello, Tim Paek, Cem Keskin, Shahram Izadi, Pushmeet Kohli, David Kim, David Sweeney, Antonio Criminisi, Jamie Shotton, Sing Bing Kang
2014 ACM Transactions on Graphics  
We use hybrid classification-regression forests to learn how to map from near infrared intensity images to absolute, metric depth in real-time.  ...  (c, d) Simple hardware modifications allow active illuminated near infrared images to be captured from the camera.  ...  Human Capture and Interaction • 86:5 b a real capture synthetic generation Figure 6 : Left: Real data is captured using a calibrated depth camera (b) registered to the NIR camera (a).  ... 
doi:10.1145/2601097.2601223 fatcat:uyqhz2hfzjdmlf2t5qo2xz3p4e

Targeted enrichment of the black cottonwood (Populus trichocarpa) gene space using sequence capture

Lecong Zhou, Jason A Holliday
2012 BMC Genomics  
As re-sequencing the genome of large numbers of samples is still cost-prohibitive in many cases, methods for genome complexity reduction have been developed in attempts to capture most ecologicallyrelevant  ...  One of these approaches is sequence capture, in which oligonucleotide baits specific to genomic regions of interest are synthesized and used to retrieve and sequence those regions.  ...  Acknowledgments We would like to thank Kyle Peer, Clay Sawyers, and Deborah Bird for assistance with plant propagation, as well as the following organizations and individuals for providing genetic material  ... 
doi:10.1186/1471-2164-13-703 pmid:23241106 pmcid:PMC3542275 fatcat:dhgdoaionrbaxeow3cplgndc2y

Barcode Imaging Using a Light Field Camera [chapter]

Xinqing Guo, Haiting Lin, Zhan Yu, Scott McCloskey
2015 Lecture Notes in Computer Science  
We present a method to capture sharp barcode images, using a microlens-based light field camera.  ...  Relative to standard barcode readers, which typically use fixed-focus cameras in order to reduce mechanical complexity and shutter lag, employing a light field camera significantly increases the scanner's  ...  Similar to the first case, we can also obtain a one-to-one mapping between the depth and average variance.  ... 
doi:10.1007/978-3-319-16181-5_40 fatcat:hmq4rvdsrjcqjnqlyzeesame3i

Flood Inundation Modelling of Flash Floods in Steep River Basins and Catchments

2017 Water  
The main objective of this study was to determine a general threshold value of the bottom slope that could be used by decision makers as an orientation guide to ascertain when to use a specific type of  ...  Nonetheless, decision makers are often reluctant to implement more complex modelling tools into practical flood inundation modelling studies, unless evidence is provided to establish when such refined  ...  The authors would also like to thank Thomas Green from Advance Research Computing-Cardiff University (ARCCA) for his assistance in using the University's high-performance computing facilities.  ... 
doi:10.3390/w9090705 fatcat:pretqstui5bkfgwgms3vs4l6gy

Subsurface Temperature Estimation from Sea Surface Data Using Neural Network Models in the Western Pacific Ocean

Haoyu Wang, Tingqiang Song, Shanliang Zhu, Shuguo Yang, Liqiang Feng
2021 Mathematics  
Moreover, there were pronounced seasonal variation signals in the upper layers (the upper 200 m), however, this signal gradually diminished with increasing depth.  ...  In the model experiment, the rasterized monthly average data from 2005–2015 and 2016 were selected as the training and testing set, respectively.  ...  In addition, with the increase of depth, the change of RMSE tended to be gentle. From 500 m to 2000 m, the average RMSE of Case 1 to Case 5 was 0.97, 0.96, 0.75, 0.94, and 0.68 • C.  ... 
doi:10.3390/math9080852 doaj:aca7536215cf488f8a87f5f8879b428b fatcat:56znkp5hvbb5taffayu6gcz46q

Learning Effective RGB-D Representations for Scene Recognition

Xinhang Song, Shuqiang Jiang, Luis Herranz, Chengpeng Chen
2019 IEEE Transactions on Image Processing  
Another limitation is the short range of depth sensors (typically 0.5m to 5.5m), resulting in depth images not capturing distant objects in the scenes that RGB images can.  ...  using weak supervision via patches.  ...  Although the predictions for RGB and depth can also be averaged, we find that it is more effective to combine them using a fully connected layer. This also allows us to train the model end-to-end.  ... 
doi:10.1109/tip.2018.2872629 pmid:30281448 fatcat:lnhv5g46s5dpngmstriivjncgy

Efficient large scale acquisition of building interiors

Gleb Bahmutov, Voicu Popescu, Mihai Mudure
2006 ACM SIGGRAPH 2006 Sketches on - SIGGRAPH '06  
A corridor section is modeled by acquiring a depth enhanced panorama (DEP) at each one of its two ends and by fitting proxy geometry to the two DEPs.  ...  Most of the acquisition time budget is spent on the parts of the scene with complex geometry.  ...  We thank Elisha Sacks for his contributions to the ModelCamera project.  ... 
doi:10.1145/1179849.1180008 dblp:conf/siggraph/BahmutovPM06 fatcat:ovooojna3rb55ceq43zpfylicu

Efficient Large Scale Acquisition of Building Interiors

Gleb Bahmutov, Voicu Popescu, Mihai Mudure
2006 Computer graphics forum (Print)  
A corridor section is modeled by acquiring a depth enhanced panorama (DEP) at each one of its two ends and by fitting proxy geometry to the two DEPs.  ...  Most of the acquisition time budget is spent on the parts of the scene with complex geometry.  ...  We thank Elisha Sacks for his contributions to the ModelCamera project.  ... 
doi:10.1111/j.1467-8659.2006.00985.x fatcat:oxyotmmgtnfktojvc7n74hhzcm

Efficient disparity map generation for moving multi-camera system using TOF depth sensor

Yun-Suk Kang, Yo-Sung Ho
2013 2013 20th International Conference on Systems, Signals and Image Processing (IWSSIP)  
In order to solve this problem, we employ a time-of-flight (TOF) depth sensor as a guide to find the minimum and maximum disparity values for each frame.  ...  Thus, computational complexity can be increased and the quality of generated disparity can be degraded since the stereo matching operation has to deal with a wide range of the disparity candidates.  ...  These input disparity values to the stereo matching are calculated using the TOF depth images.  ... 
doi:10.1109/iwssip.2013.6623451 fatcat:aawehhljd5cqtmomi22b2n24gy

Acceleratingk+-buffer using efficient fragment culling

Andreas A. Vasilakis, Georgios Papaioannou
2015 Proceedings of the 19th Symposium on Interactive 3D Graphics and Games - i3D '15  
When the value of the counter reaches k, the current bucket's depth is returned to the Z-buffer. The average-case complexity of this pass is O(k).  ...  Despite the additional geometry passes needed, performance increases by 20% to 50%, when rendering the hairball (2.8M, 150) and needle tree (43.2T, 100) models (# triangles, average depth complexity) with  ... 
doi:10.1145/2699276.2721402 dblp:conf/si3d/VasilakisP15 fatcat:mookl6nmxzcjznqc4ms5wdvc3q

Fast realistic refocusing for sparse light fields

Chao-Tsung Huang, Jui Chin, Hong-Hui Chen, Yu-Wen Wang, Liang-Gee Chen
2015 2015 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)  
For showing realistic refocusing, a light-field wafer-level-optics array is implemented, and its refocused images are compared to pictures captured by a real camera.  ...  Then we propose a fast refocusing algorithm using a view interpolation method which is about 30x faster than VSRS-1D-Fast.  ...  Three depth-assisted approaches can be used to reduce aliasing: depth-dependent blurring [4, 5] , layered depths [6] , and view interpolation [7, 8, 9] .  ... 
doi:10.1109/icassp.2015.7178155 dblp:conf/icassp/HuangCCWC15 fatcat:2gahmwk4ofhkrh47mkmfcwrwzq
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