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Polymer chemistry applications of Cyrene™ and its derivative Cygnet 0.0 as safer replacements for polar aprotic solvents

Roxana A. Milescu, Anna Zhenova, Marco Vastano, Richard Gammons, James H. Clark, Con R. McElroy, Alessandro Pellis
2021 ChemSusChem  
New polymeric membranes from cellulose acetate, polysulfone, and polyimide are manufactured by using Cyrene, Cygnet 0.0, and their blend.  ...  The use of a 50 wt % Cygnet-Cyrene mixture makes a practical difference in the production of flat sheet membranes by nonsolvent-induced phase separation.  ...  We extend our thanks to INGE.BASF for providing PES3020 used in this project, Dr Meg Stark and Karen Hodgkinson from Bioscience Technology Facility, Biology Department, University of York for SEM micrographs  ... 
doi:10.1002/cssc.202101125 pmid:34219405 pmcid:PMC8457101 fatcat:l3lcsqyhlrba3lc3xwmygybjra

The Trumpeter Swan. Its History, Habits and Population in the United States

M. M. Nice, Winston E. Banko
1961 Bird-Banding  
Elk Refuge, Wyoming, 1944 to 1957 Pairs Cygnets Cygnets Pairs Cygnets Cygnets Year nested initially raised to Year nested initially raised to Life zone names based on unpublished information  ...  In the case of the gray individuals, by far the most common, the head, neck, and back are mouse-gray with the underparts quite white.  ...  , 118- use, 12, 13, 19.  ... 
doi:10.2307/4510872 fatcat:lry3uvxwrvalncfrnx3aqjcta4

Holocene vegetation–fire–climate linkages in northern Yellowstone National Park, USA

Mariana A. Huerta, Cathy Whitlock, Jason Yale
2009 Palaeogeography, Palaeoclimatology, Palaeoecology  
Yellowstone National Park has been an important location for paleoecologic studies that focus on the use of charcoal data to reconstruct past fire activity and on the role of climate variations in shaping  ...  From 11,000 to 7600 cal yr BP, the presence of a closed forest of Pinus and some Picea is attributed to high levels of winter moisture, but high fire activity indicates that summers were drier than at  ...  Bartlein provided the precipitation base map used in Fig. 1 , the PDSI data on Fig., as well as insights on the paleoclimate history. J. Gage, C. Carr, and T.  ... 
doi:10.1016/j.palaeo.2008.10.015 fatcat:eb6xng2ez5bndkxejgtsov22yy

Cyclic Avian Mass Mortality in the Northeastern United States Is Associated with a Novel Orthomyxovirus

Andrew B. Allison, Jennifer R. Ballard, Robert B. Tesh, Justin D. Brown, Mark G. Ruder, M. Kevin Keel, Brandon A. Munk, Randall M. Mickley, Samantha E. J. Gibbs, Amelia P. A. Travassos da Rosa, Julie C. Ellis, Hon S. Ip (+7 others)
2014 Journal of Virology  
that it is closely related to the recently identified Cygnet River virus (CyRV) from South Australia, suggesting that WFBV and CyRV may be geographic variants of the same virus.  ...  Although longitudinal disease investigations have uncovered potential contributing factors responsible for these outbreaks, detecting a primary etiological agent has proven enigmatic.  ...  Use of products or trade names is not an endorsement by the United States government.  ... 
doi:10.1128/jvi.02019-14 pmid:25392223 pmcid:PMC4300652 fatcat:fanaer7hpnaapjd23qsorhzbze

Multi-drug Resistance Protein 4 (MRP4)-mediated Regulation of Fibroblast Cell Migration Reflects a Dichotomous Role of Intracellular Cyclic Nucleotides

Chandrima Sinha, Aixia Ren, Kavisha Arora, Chang-Suk Moon, Sunitha Yarlagadda, Weiqiang Zhang, Satish B. Cheepala, John D. Schuetz, Anjaparavanda P. Naren
2012 Journal of Biological Chemistry  
Significance: Inhibition of MRP4 facilitates wound repair. . 2 The abbreviations used are: MRP4, multidrug resistance protein 4; MEF, mouse embryonic fibroblast; IBMX, isobutylmethylxanthine; PKA, cAMP-dependent  ...  To test our hypothesis and to understand the dichotomous role of cyclic nucleotides in cell migration, we used MEFs from Mrp4 ϩ/ϩ and Mrp4 Ϫ/Ϫ mice and NIH 3T3 cells for migration assays.  ...  The protein bands were detected by chemiluminescence using ECL TM Western blotting detection reagents from GE Healthcare. We loaded 50 g of total protein per lane.  ... 
doi:10.1074/jbc.m112.435925 pmid:23264633 pmcid:PMC3567633 fatcat:vm57hf2g45fhhebyparxkkhfem

Demographic outcomes of diverse migration strategies assessed in a metapopulation of tundra swans

Craig R. Ely, Brandt W. Meixell
2016 Movement Ecology  
Estimates of annual survival probability varied by wintering area (Pacific coast, Alaska Peninsula, and Eastern seaboard) and ranged from 0.79 (95%CI: 0.70-0.88) to 1.0, depending on criteria used to discern  ...  We monitored the fates of 50 satellite-implanted tundra swans (Cygnus columbianus) over 4 years from five disparate breeding areas in Alaska, and used known-fate analyses to estimate monthly survival probability  ...  Acknowledgements We are grateful to the U.S. Geological Survey (USGS), and the U.S.  ... 
doi:10.1186/s40462-016-0075-8 pmid:27134751 pmcid:PMC4852103 fatcat:rujowu4sfvgzpoyrfl7xqtyky4

Accommodating change

Latifa Al-Abdulkarim, Katie Atkinson, Trevor Bench-Capon
2016 Artificial Intelligence and Law  
The third of Berman and Hafner's early nineties papers on reasoning with legal cases concerned temporal context, in particular the evolution of case law doctrine over time in response to new cases and  ...  In this paper we consider the ways in which changes in case law doctrine can be accommodated in a recently proposed methodology for encapsulating case law theories (the ANGELIC methodology based on Abstract  ...  The debt of the second and third authors to the work of Carole and Don Berman, in particular Berman and Hafner (1993) , is considerable: much of our work has explored value-based reasoning in case law  ... 
doi:10.1007/s10506-016-9190-5 fatcat:qo3p3pyszjasdpsnz4sk7hhlhy

Molecular Detection of Hematozoa Infections in Tundra Swans Relative to Migration Patterns and Ecological Conditions at Breeding Grounds

Andrew M. Ramey, Craig R. Ely, Joel A. Schmutz, John M. Pearce, Darryl J. Heard, Reiner Albert Veitia
2012 PLoS ONE  
We investigated patterns of hematozoa infection in three populations of tundra swans that breed in Alaska using satellite tracking to infer host movement and molecular techniques to assess the prevalence  ...  Genetic diversity of blood parasites in populations of tundra swans appeared to be relative to hematozoa prevalence.  ...  Any use of trade names is for descriptive purposes only and does not imply endorsement by the U.S. Government. Author Contributions  ... 
doi:10.1371/journal.pone.0045789 pmid:23049862 pmcid:PMC3458064 fatcat:kvfx7m5lz5dmxfz3xa6gzgrvpm

Typhoons in the Philippine Islands, 1901-1934

P Ribera, R García-Herrera, L Gimeno, E Hernández
2005 Climate Research (CR)  
Thus, documentary and other paleoclimatological techniques have been used to reconstruct TC occurrence.  ...  Due to the involved timescales, the instrumental records have demonstrated too short to provide a complete picture.  ...  Thus, we have examined the original reports of the Cygnet, Antelope and Centurion, cited in table 2. All of them use the term storm which was only used for very severe wind conditions.  ... 
doi:10.3354/cr029085 fatcat:rggwzyp4sjhbbfsht6v3owqgxe

Genetic manipulation of cyclic nucleotide signaling during hippocampal neuroplasticity and memory formation

Michy P. Kelly, Pim R.A. Heckman, Robbert Havekes
2020 Progress in Neurobiology  
Here, we will provide an overview of studies using genetic approaches to interrogate the role cyclic nucleotide signaling plays in hippocampus-dependent memory processes and synaptic plasticity.  ...  Particular attention is given to genetic techniques that measure real-time changes in cyclic nucleotide levels as well as newly-developed genetic strategies to transiently manipulate cyclic nucleotide  ...  FRET-based biosensors for detecting cAMP The most well-known EPAC-based probes are called 'ICUE' (indicator of cAMP using EPAC).  ... 
doi:10.1016/j.pneurobio.2020.101799 pmid:32360536 fatcat:areqe3udufepdcaebkw6owmu64

FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons

Gaia Calamera, Dan Li, Andrea Hembre Ulsund, Jeong Joo Kim, Oliver C. Neely, Lise Román Moltzau, Marianne Bjørnerem, David Paterson, Choel Kim, Finn Olav Levy, Kjetil Wessel Andressen
2019 Communications Biology  
Our aim was to develop a FRET-based cGMP biosensor with high affinity for cGMP as a tool for intracellular signaling studies.  ...  We used the carboxyl-terminal cyclic nucleotide binding domain of Plasmodium falciparum cGMP-dependent protein kinase (PKG) flanked by different FRET pairs to generate two cGMP biosensors (Yellow PfPKG  ...  This demonstrates that using FRET sensors can be a more sensitive tool to detect cGMP in cells.  ... 
doi:10.1038/s42003-019-0641-x pmid:31925208 fatcat:ints3qplgfbj3l6zkvchod32ii

Activation of TRPM7 Channels by Phospholipase C-coupled Receptor Agonists

Michiel Langeslag, Kristopher Clark, Wouter H. Moolenaar, Frank N. van Leeuwen, Kees Jalink
2006 Journal of Biological Chemistry  
Using FRET assays for second messengers, we have shown that the TRPM7-dependent Ca 2؉ increase closely correlates with activation of PLC.  ... 2 The abbreviations used are: TRPM, TRP (melastatin-related); TRP, transient receptor potential; BAPTA, 1,2-bis(2-aminophenoxy)ethane-N,N,NЈ,NЈ-tetraacetic acid; BK, bradykinin; EDTA-AM, ethylenediaminetetraacetic  ...  / TRPM7 cells as detected by a protein kinase A-based FRET probe (left panel).  ... 
doi:10.1074/jbc.m605300200 pmid:17095511 fatcat:55ubmxxkkfhb7ghjakx2gei6va

Application of FRET probes in the analysis of neuronal plasticity

Yoshibumi Ueda, Showming Kwok, Yasunori Hayashi
2013 Frontiers in Neural Circuits  
Then the evolution of color variants of GFP opened the door to the application of Förster resonance energy transfer (FRET), which is now widely recognized as a powerful tool to study complicated signal  ...  Employment of fluorescent lifetime imaging microscopy (FLIM) allows the precise detection of FRET in small subcellular structures such as dendritic spines.  ...  Cleavage-based approach The first reported GFP-based probe detecting Factor Xa activity employed the cleavage-based approach ( Figure 1A ) (Mitra et al., 1996) .  ... 
doi:10.3389/fncir.2013.00163 pmid:24133415 pmcid:PMC3794420 fatcat:4vhyjy4wvje55dzjbmvecdx4be

Past-Forwarding Ancient Calamities. Pathways for Making Archaeology Relevant in Disaster Risk Reduction Research

Felix Riede
2017 Humanities  
In a deep historical perspective, human communities of many different kinds have been affected by numerous kinds of natural disasters that may provide useful data for scenario-based risk reduction measures  ...  'Past-forwarding' is here intended to signal the use of such deep historical information in concerns for contemporary and future resilience.  ...  The founding sponsors had no role in the design of the study; in the collection, analyses or interpretation of data; in the writing of the manuscript; nor in the decision to publish the results.  ... 
doi:10.3390/h6040079 fatcat:p26ud56gdvc4nb7mdxmxvavrdq

Genetically Encodable Fluorescent Biosensors for Tracking Signaling Dynamics in Living Cells

Robert H. Newman, Matthew D. Fosbrink, Jin Zhang
2011 Chemical Reviews  
used for a number of RET-based applications.  ...  amenable to detection by electron microscopy (EM).  ...  Work in the lab is funded by NIH (DK073368 and DP1OD006419 and 3M (to J. Z). Biographies  ... 
doi:10.1021/cr100002u pmid:21456512 pmcid:PMC3092831 fatcat:jw4csbg43fdi7csnjbzto4dhtm
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