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Use It and Improve It or Lose It: Interactions between Arm Function and Use in Humans Post-stroke

Yukikazu Hidaka, Cheol E. Han, Steven L. Wolf, Carolee J. Winstein, Nicolas Schweighofer, Jörn Diedrichsen
2012 PLoS Computational Biology  
Use it and improve it, or lose it" is one of the axioms of motor therapy after stroke. There is, however, little understanding of the interactions between arm function and use in humans post-stroke.  ...  Using a Bayesian regression framework, we systematically compared this model with competitive models that included, or not, interactions between function and use.  ...  data retrieval and preparation.  ... 
doi:10.1371/journal.pcbi.1002343 pmid:22761551 pmcid:PMC3385844 fatcat:66arlte37bc2danhsd4os2qp6m

Use it and/or lose it—experience effects on brain remodeling across time after stroke

Rachel P. Allred, Soo Young Kim, Theresa A. Jones
2014 Frontiers in Human Neuroscience  
The reorganization of neural connectivity after stroke is a complex multiphasic process interacting with glial and vascular changes.  ...  The process of brain remodeling after stroke is time-and neural activity-dependent, and the latter makes it inherently sensitive to behavioral experiences.  ...  Kelly Tennant and Abigail Kerr for help with the figure. Supported by NINDS RO1 NS056839 and NS078791.  ... 
doi:10.3389/fnhum.2014.00379 pmid:25018715 pmcid:PMC4072969 fatcat:hbdhoftqvrfn5lzgumte7aqu3m

Movement Pattern Recognition in Physical Rehabilitation - Cognitive Motivation-based IT Method and Algorithms

Veronika Szücs, Tibor Guzsvinecz, Attila Magyar
2020 Acta Polytechnica Hungarica  
The presented method combines the advantages of human-computer interaction-based movement therapy, with the cognitive property of intelligent decision-making systems.  ...  In this paper, a solution is presented to support both existing and future movement rehabilitation applications.  ...  Petra Marton for her contribution in the data logger application development, to Ms. Mónika Ozsváth for her contribution in the development of data conditioning and reconstruction.  ... 
doi:10.12700/aph.17.2.2020.2.12 fatcat:gyhhljactjcz5pel56dskcnxfa

Virtuous and Vicious Cycles of Arm Use and Function Post-stroke

Belen R. Ballester, Carolee Winstein, Nicolas Schweighofer
2022 Frontiers in Neurology  
Altogether, this model points to a user-centered approach to recovery post-stroke that is tailored to the participant's level of arm use and designed to motivate and engage in self-practice through progressive  ...  If not, one enters a vicious cycle of declining arm use and function.  ...  ACKNOWLEDGMENTS We thank Cheol Han, Yukikazu Hidaka, Sujin Kim, Chunji Wang, Yi-An Chen, John Monterosso, Michael Arbib, Steve Wolf, Rini Varghese, Marika Demers, Jens Nirme, Armin Duff, Martina Maier, and  ... 
doi:10.3389/fneur.2022.804211 pmid:35422752 pmcid:PMC9004626 fatcat:7zfp7e2yf5am7bkjdmmisbontq

The CABANA Debate – Once a Treatment Becomes Popular, it is Hard to Interpret the Results in Medicine

Ozcan Ozeke, Serkan Cay, Firat Ozcan, Serkan Topaloglu, Dursun Aras, Department of Cardiology, Health Sciences University, Ankara City Hospital, Ankara, Turkey, Department of Cardiology, Health Sciences University, Ankara City Hospital, Ankara, Turkey, Department of Cardiology, Health Sciences University, Ankara City Hospital, Ankara, Turkey, Department of Cardiology, Health Sciences University, Ankara City Hospital, Ankara, Turkey, Department of Cardiology, Health Sciences University, Ankara City Hospital, Ankara, Turkey
2019 European Journal of Arrhythmia & Electrophysiology  
'Justice delayed is justice denied' is a legal cliché, meaning that if timely justice is not provided to the sufferer, it loses its importance and violates human rights.  ...  At a median follow-up of 4 years, the difference in the primary endpoint, including death, disabling stroke, serious bleeding or cardiac arrest, between patients assigned ablation and those assigned drug  ...  'Justice delayed is justice denied' is a legal cliché meaning that if timely justice is not provided to the sufferer, it loses it importance and violates human rights.  ... 
doi:10.17925/ejae.2019.5.1.17 fatcat:uofxrspnojhmnfp7xpizoy3txu

Augmented Reality Assisted Upper Limb Rehabilitation Following Stroke [chapter]

Kimberlee Jordan, Marcus King
2011 Augmented Reality - Some Emerging Application Areas  
All studies involving human participants were approved by the University of Otago, NZ Human Ethics Committee or by the NZ Health and Disabilities, Upper South A, Regional Ethic Committee.  ...  The authors wish to thank the stroke survivors and clinicians who willingly gave their time and thoughts during development of the interventions described here.  ...  Subjective well-being is reduced one year post stroke and this is mainly attributed to poor arm function (Wyller et al., 1997) .  ... 
doi:10.5772/25954 fatcat:agfbyciaofeq7kyr4cxyzes6om

Evolutionary medicine: its scope, interest and potential

S. C. Stearns
2012 Proceedings of the Royal Society of London. Biological Sciences  
It first describes the range of topics covered by evolutionary medicine, which include human genetic variation, mismatches to modernity, reproductive medicine, degenerative disease, hostpathogen interactions  ...  This review is aimed at readers seeking an introductory overview, teaching courses and interested in visionary ideas.  ...  Peter Ellison and an anonymous reviewer improved a draft.  ... 
doi:10.1098/rspb.2012.1326 pmid:22933370 pmcid:PMC3479795 fatcat:dryjskdbbjarrpkb63fmgioy44

Computational neurorehabilitation: modeling plasticity and learning to predict recovery

David J. Reinkensmeyer, Etienne Burdet, Maura Casadio, John W. Krakauer, Gert Kwakkel, Catherine E. Lang, Stephan P. Swinnen, Nick S. Ward, Nicolas Schweighofer
2016 Journal of NeuroEngineering and Rehabilitation  
Despite progress in using computational approaches to inform medicine and neuroscience in the last 30 years, there have been few attempts to model the mechanisms underlying sensorimotor rehabilitation.  ...  Here, we therefore discuss Computational Neurorehabilitation, a newly emerging field aimed at modeling plasticity and motor learning to understand and improve movement recovery of individuals with neurologic  ...  DJR was supported by grant NIH R01 HD062744 EB was supported by grants EU-FP7 ICT-601003 BALANCE, ICT-2013-10 SYMBITRON, and EU-H2020 ICT-644727 COGIMON.  ... 
doi:10.1186/s12984-016-0148-3 pmid:27130577 pmcid:PMC4851823 fatcat:4yoaf76fpjgulc4rq45zn2x4yi

Drink Like a Lawyer: The Neuroscience of Substance Use and Its Impact on Cognitive Wellness

Debra S. Austin
2014 Social Science Research Network  
Armed with the power of NQ, law students, lawyers, law professors, and judges can make decisions that improve cognitive function.  ...  loss supplements contained ephedrine, but it produces sympathomimetic symptoms including increased blood pressure and risk of stroke or heart attack. 427 Ephedrine was used in asthma medicine because  ...  , cycling, rowing, or CrossFit. 720 It also releases endocannabinoids in the lawyer brain, making him feel better during and after exercise. 721 D.  ... 
doi:10.2139/ssrn.2503021 fatcat:ibo6yogyzvg77nwn4tyfijwi5e

Post-Stroke Balance Impairments Assessment: Clinical Scales and Current Technologies [chapter]

Paulina Ortega-Bastidas, Britam Gómez, Karen Barriga, Francisco Saavedra, Pablo Aqueveque
2022 Post-Stroke Rehabilitation [Working Title]  
As a closure, we explain the importance of early detection and treatment of balance impairments in the post-stroke population to prevent falls.  ...  Finally, the application of new technologies and the technological advances used in clinical settings for human analysis focusing on balance are addressed.  ...  Acknowledgements This work was supported by the Vice-rectory for research and development (VRID) of the Universidad de Concepción: "Clinical validation of a human motion  ... 
doi:10.5772/intechopen.101984 fatcat:4uw6ssbzgfhd5mddbqeqo6xfdu

Is it clever for doctors to take smart drugs?

Marika Davies
2016 BMJ (Clinical Research Edition)  
Bioactive: Materials that interact with or affect (human) cells or tissues.  ...  alterations to the environment itself that enhance human interactions with it.  ... 
doi:10.1136/bmj.h5593 fatcat:ufupr6kc45e7dnajjoebkx226a

Breath-holding and its breakpoint

M. J. Parkes
2005 Experimental Physiology  
This article reviews the basic properties of breath-holding in humans and the possible causes of the breath at breakpoint.  ...  The simplest objective measure of breath-holding is its duration, but even this is highly variable.  ...  Nevertheless this term is used here for clarity, even though the closest approximation to its measurement in humans can only be from recording autonomic outflow or skeletal muscle activity.  ... 
doi:10.1113/expphysiol.2005.031625 pmid:16272264 fatcat:5ogjrukkv5h7ta4nqcuqtcfqzy

Design and Implement an Exoskeleton Arm for Reinforcement the Human Muscles after Stroke

Duha Qais Abd-ul-Amir, Auns Qusai Hashim, Abdulnasir Hussin Ameer
2019 مجلة النهرين للعلوم الهندسية  
After the design was completed, 19 subjects participated in this study: 4 healthy subjects, and 15 post-stroke patients.The results showed the benefit of robotic exoskeleton in increasing the elbow range  ...  Mobility limitations in stroke survivors yield negative impacts on the quality of life for such individuals. Rehabilitation is needed to help them recover and regain mobility.  ...  Figure ( 5 5 ): Measuring elbow angle.• Exoskeleton device is the intrinsic interaction between human and exo-arm. This interaction is twofold.  ... 
doi:10.29194/njes.22040252 fatcat:mew5jtbpkfgujncolomirbew44

Nanotechnology and its implications in therapeutics [chapter]

Anuja Patil, Harsiddhi Chaudhary, Kisan Jadhav, Vilasrao Kadam
2015 Nano based drug delivery  
Our research group is investigating the interaction of RGD-Rosette nanotubes (RGD-RNT) to αvβ3 integrins, following cell signalling through P38 kinases and its function in human lung epithelial cells,  ...  Since it is intermittent, it can miss dangerous fluctuations in blood glucose concentrations between tests.  ... 
doi:10.5599/obp.8.1 fatcat:xtf6ozowqreqdew7z5znxwrf54

System Framework of Robotics in Upper Limb Rehabilitation on Poststroke Motor Recovery

Kai Zhang, Xiaofeng Chen, Fei Liu, Haili Tang, Jing Wang, Weina Wen
2018 Behavioural Neurology  
Then, the comparisons of human-machine interactions, control strategies, driving modes, and training modes are described.  ...  Neurological impairments such as stroke cause damage to the functional mobility of survivors and affect their ability to perform activities of daily living.  ...  It is also necessary to improve the response speed of the signal to ensure the timeliness of the interaction between the virtual environment and humans.  ... 
doi:10.1155/2018/6737056 fatcat:wjkefrcxtbhwrcub6o5lzit7xi
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