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Western Medical Research conference (formerly Western Regional Meeting), January 25–27 2018, Carmel, California

2018 Journal of Investigative Medicine  
Clinicians may need to be more aware of HS patient's symptoms of depression and their difficulties navigating through the healthcare system.  ...  He had gradual overgrowth of the right leg and prominent superficial collateral veins on his back and thighs with MR imaging showing absence of multiple deep veins.  ...  While magnetic resonance imaging (MRI) can non-invasively and accurately quantify these biometrics, it requires breath-holding (BH) and sedation.  ... 
doi:10.1136/jim-2017-000663.224 fatcat:auen6aqzifbyji2lamb25jy7ty

Bone health in Gambian women: impact and implications of rural-to-urban migration and the nutrition transition

Sarah Dalzell, Apollo-University Of Cambridge Repository, Apollo-University Of Cambridge Repository, Dr Gail Goldberg
Predictions indicate that hip fracture incidence will increase 6-fold in Africa and Asia by 2050, partially attributed to demographic transition and population ageing.  ...  Bone phenotype (bone mineral content (BMC); bone area (BA); aBMD, and size-adjusted BMC (adjusted for height, weight and BA) of the whole-body, lumbar spine and hip) was measured by dual energy x-ray absorptiometry  ...  if there was any uncertainty.  ... 
doi:10.17863/cam.30976 fatcat:ckkj4pjtgvepfc5gyaaa3qhf7e

Super-resolution imaging of cell-surface Sonic hedgehog multimolecular signalling complexes

Mirella Koleva, Mark Neil, Anthony Magee, Engineering And Physical Sciences Research Council
optical imaging beyond the diffraction limit.  ...  Gaining an understanding of its signalling mechanism is central to inventing preventative measures and treatments against this disease.  ...  Radicals have one unpaired electron in an open-shell configuration.  ... 
doi:10.25560/24829 fatcat:pqy265otvvd7lfm73zcqdqjf4e

The metabolic sequelae of oesophago-gastric resection

Geoffrey Peter Roberts, Apollo-University Of Cambridge Repository, Apollo-University Of Cambridge Repository, Fiona Gribble
for the challenges faced by this patient population.  ...  In the surgical groups, an oral glucose tolerance test (OGTT) resulted in enhanced secretion of satiety and incretin gut hormones (GLP-1, GIP, PYY) and insulin, followed by hypoglycaemia in a cohort of  ...  The team at the Cambridge Oesophago-gastric centre (surgeons Mr Safranek, Mr Hindmarsh, Mr Sujendran, Mr Bennett and Miss Wells; nurses Ben Smith and Nyarai Chinyama; dietitians Sam Grimes and Nicola Sunderland  ... 
doi:10.17863/cam.37362 fatcat:blshisbzovhrph2y7cobajwk5i

Time-dependent metabolic phenotyping of inflammatory dysregulation

Arnaud Wolfer, Jeremy K Nicholson, Timothy MD Ebbels
The function of inflammation in the healing process as well as its involvement in most major diseases is well established, yet the specific mechanism by which it contributes to the pathogenesis is still  ...  A rich and functional description of a patient health status is the fundamental basis for the personalisation of treatment and the targeting of interventions.  ...  Sofia Fountana and Mr. Thomas Payne.  ... 
doi:10.25560/58241 fatcat:ylntlxjhwvb6vlicwgsquavaqq

Phenotypic heterogeneity in high-grade serous ovarian cancer: evidence for a stochastic model of proliferation

Douglas Hall, Apollo-University Of Cambridge Repository, Apollo-University Of Cambridge Repository, James Brenton
These cells are uniquely able to regrow tumours in the lab, and are enriched by chemotherapy.  ...  An alternative approach was also tested, assessing the symmetry of cell division by immunofluorescence, but is not yet optimised.  ...  images.  ... 
doi:10.17863/cam.38510 fatcat:v5grh2cuq5f53lsi6tcwzwlgdm

The biology of mesenchymal stem cells and the utility of the cellular therapy in Multiple Sclerosis

Rehiana Ali, Paolo Muraro, Multiple Sclerosis Society Of Great Britain And Northern Ireland, UK Stem Cell Foundation
It formed part of a wider collaborative study in MS (MESEMS). 13 patients had successful BM harvests with a mean yield of 3.21 x 106 cells/kg (range 1.66 – 6.78 x 106) but a further six failed to reach  ...  the required dose and were withdrawn.  ...  It has also been shown that treatment with fingolimod decreased NFL levels compared to placebo and such changes were associated with improvements in relapse rates and MR imaging.  ... 
doi:10.25560/89129 fatcat:3buqukjxhjbrhpk3dhcyr7wjam