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Near-infrared spectral imaging for quality assurance of pharmaceutical products: Analysis of tablets to assess powder blend homogeneity

Robbe C. Lyon, David S. Lester, E. Neil Lewis, Eunah Lee, Lawrence X. Yu, Everett H. Jefferson, Ajaz S. Hussain
2002 AAPS PharmSciTech  
The objective of this study was to evaluate near-infrared (NIR) spectroscopic imaging as a tool to assess a pharmaceutical quality assurance problem -blend uniformity in the final dosage product.  ...  The chemical nature of each pixel could be identified by the localized spectrum associated with each pixel. Both univariate and partial least squares (PLS) images were evaluated.  ...  ACKNOWLEDGEMENTS The opinions expressed in this article are those of the authors and do not necessarily reflect the views and policies of the U.S. Food and Drug Adminstration.  ... 
doi:10.1208/pt030317 pmid:12916932 pmcid:PMC2784046 fatcat:tvvohqdm5rewvkeqr2sacfcxge

Near-infrared spectral imaging for quality assurance of pharmaceutical products: Analysis of tablets to assess powder blend homogeneity

Robbe C. Lyon, David S. Lester, E. Neil Lewis, Eunah Lee, Lawrence X. Yu, Everett H. Jefferson, Ajaz S. Hussain
2002 AAPS PharmSciTech  
The objective of this study was to evaluate near-infrared (NIR) spectroscopic imaging as a tool to assess a pharmaceutical quality assurance problem -blend uniformity in the final dosage product.  ...  The chemical nature of each pixel could be identified by the localized spectrum associated with each pixel. Both univariate and partial least squares (PLS) images were evaluated.  ...  ACKNOWLEDGEMENTS The opinions expressed in this article are those of the authors and do not necessarily reflect the views and policies of the U.S. Food and Drug Adminstration.  ... 
doi:10.1007/bf02830615 fatcat:elj73jiw2jgd7lhaxmzyy56qne

Objective quality assessment of displayed images by using neural networks

Paolo Gastaldo, Rodolfo Zunino, Ingrid Heynderickx, Elena Vicario
2005 Signal processing. Image communication  
Reliable methods for measuring perceived image quality are needed to evaluate the performances of those algorithms, and such measurements require a univariant (i.e., no-reference) approach.  ...  Considerable research effort is being devoted to the development of image-enhancement algorithms, which improve the quality of displayed digital pictures.  ...  Acknowledgements The authors wish to thank Dr. P. Carrai and Dr. G. Ferretti, Philips Research, Monza, for their assistance during the first phase of the research.  ... 
doi:10.1016/j.image.2005.03.013 fatcat:hmlutcyhcnfi3ojni3pggftgti

Diagnostic accuracy of tests for lymph node status in primary cervical cancer: a systematic review and meta-analysis

T. J. Selman, C. Mann, J. Zamora, T.-L. Appleyard, K. Khan
2008 CMAJ - Canadian Medical Association Journal  
recommendations. 18, 19 To explore the effect of study quality, we first used all the 2 × 2 tables to assess whether the quality-assessment criteria produced variation in the log of the diagnostic odds  ...  We used the existing QUADAS (quality assessment of diagnostic accuracy studies) criteria and the STARD (standards for reporting of diagnostic accuracy) criteria to generate the quality-assessment criteria  ...  Contributors: All of the authors contributed to the conception and design of the study, acquisition and interpretation of the data, and drafting and revising of the manuscript.  ... 
doi:10.1503/cmaj.071124 pmid:18362381 pmcid:PMC2267838 fatcat:5f2bfgrrmrg3xaaho6on3corwu

Color image quality assessment measure using multivariate generalized Gaussian distribution [article]

Mounir Omari, Abdelkaher Ait Abdelouahad, Mohammed El Hassouni and Hocine Cherifi
2014 arXiv   pre-print
This paper deals with color image quality assessment in the reduced-reference framework based on natural scenes statistics.  ...  Results demonstrates its effectiveness for a great variety of distortion type. Among other benefits this measure uses only very little information about the original image.  ...  To assess the performance of different image processing techniques, one has to measure the impact of the degradation induced by the processing in terms of perceived visual quality.  ... 
arXiv:1412.0111v1 fatcat:bwwrdsqjorh5zhs46nhiimfade

Factors in Intraductal Papillary Mucinous Neoplasms of the Pancreas Predictive of Lymph Node Metastasis

Kiichiro Kobayashi, Yoshihiko Sadakari, Takao Ohtsuka, Shunichi Takahata, Masafumi Nakamura, Kazuhiro Mizumoto, Masao Tanaka
2011 Pancreatology (Print)  
Univariate analysis using 61 patients having mural nodules preoperatively revealed that the size of mural nodules 6 10 mm and positive imaging findings for invasive tumor and possible LNM were significant  ...  Positive and negative predictive values of the imaging finding of invasive IPMNs for LNM were 50 and 98%, respectively. Conclusions: Standard lymph node dissection  ...  The quality of US examinations is very important to evaluate IPMNs of the pancreas and it is therefore necessary to maintain the quality of diagnostic ability for the appropriate treatment of IPMNs.  ... 
doi:10.1159/000320709 pmid:21242713 fatcat:dayswpbp75gfxmajwv7voqb6ba

Optimal timing of contrast-enhanced three-dimensional magnetic resonance left atrial angiography before pulmonary vein ablation

Susanne Löbe, Claudia Leuthäusser, Alexander Pölkow, Sebastian Hilbert, Philipp Sommer, Andreas Bollmann, Gerhard Hindricks, Ingo Paetsch, Cosima Jahnke
2013 Cardiology Journal  
image quality.  ...  To achieve high image quality of cardiovascular magnetic resonance (CMR) pulmonary vein (PV) angiography prior catheter ablation in patients with atrial fibrillation, optimal timing of the angiographic  ...  Thus, 3D, PV angiography prior to PV ablation procedures necessitates a real-time assessment with visual determination of individual contrast agent passage time to ensure consistently high CMR image quality  ... 
doi:10.5603/cj.a2019.0112 pmid:31909472 pmcid:PMC8276996 fatcat:44wnwppxq5hohioww2h2ddot3i

Factors Impacting Echocardiographic Imaging after the Fontan Procedure: A Report from the Pediatric Heart Network Fontan Cross-Sectional Study

Richard V. Williams, Renee Margossian, Minmin Lu, Andrew M. Atz, Timothy J. Bradley, Michael Jay Campbell, Steven D. Colan, Dianne Gallagher, Wyman W. Lai, Gail D. Pearson, Ashwin Prakash, Girish Shirali (+1 others)
2013 Echocardiography  
Univariate and multivariable modeling were performed to assess factors associated with quality and ability to obtain images sufficient for pre-specified quantitative analysis.  ...  Results-A total of 543 echocardiograms were obtained. The quality of echocardiograms improved over the duration of the study.  ...  In addition, we sought to identify patient-related and non-patient-related factors impacting subjective assessment of echocardiographic image quality and the ability to complete quantitative assessment  ... 
doi:10.1111/echo.12219 pmid:23614708 pmcid:PMC3732542 fatcat:pyovg6afn5hg7ag5u46wrhoxke

Biomechanical CT metrics are associated with patient outcomes in COPD

Sandeep Bodduluri, Surya P Bhatt, Eric A Hoffman, John D Newell, Carlos H Martinez, Mark T Dransfield, Meilan K Han, Joseph M Reinhardt
2017 Thorax  
Methods We applied image registration techniques to paired inspiratory-expiratory CT scans and derived the Jacobian determinant of the deformation field between the two lung volumes to map local volume  ...  We analysed 490 participants with COPD with multivariable regression models to assess strengths of association between traditional CT metrics of disease and the Jacobian determinant with respiratory morbidity  ...  Diagnostics, a company that is commercializing lung image analysis software developed, in part, at the University of Iowa; CHM reports grants from NIH; MKH reports personal fees from BI, personal fees  ... 
doi:10.1136/thoraxjnl-2016-209544 pmid:28044005 pmcid:PMC5526353 fatcat:wzom62vzc5hzxdfdekz3vyy5py

Quality of Life in Ovarian Cancer: A Threat to Women Health in Pakistan

Madeeha Malik, Emmama Jamil, Azhar Hussain
2020 International Journal of Research in Pharmaceutical Sciences  
The present study was designed to assess the quality of life among ovarian cancer patients in Pakistan. A descriptive cross-sectional study design was used. A pre validated questionnaire, i.e.  ...  The results of the current study highlighted a significant difference (p ≥ 0.05) in the quality of life of women with respect to all of the indicators.  ...  Con lict of Interest The authors declare that they have no con lict of interest for this study.  ... 
doi:10.26452/ijrps.v11ispl4.4663 fatcat:zjfdhrqrkvejnc2cr5fbhwfi74

The risk of ischemic stroke is associated with coronary atherosclerotic burden, but not with myocardial ischemia in patients with suspected coronary artery disease

H. S. Lee, Y. J. Kim, Y. E. Yoon, H. L. Kim, S. P. Lee, H. K. Kim, G. Y. Cho, D. W. Sohn, B. H. Oh, Y. B. Park
2013 European Heart Journal  
Cardiovascular computed tomography imaging 839 rograde approach alone and 13 (38.2%) of the attempts utilized a bidirectional approach. The overall success rate per attempt was 85.3%.  ...  Univariable and multivariable Cox regression analysis was used to determine the prognostic values, and discriminative power was assessed with continuous net reclassification improvement (cNRI).  ...  Image quality was assessed using a nominal scale ranging from 1 to 4 -1 representing non-diagnostic image quality, 4 representing excellent image quality).  ... 
doi:10.1093/eurheartj/eht310.p4679 fatcat:7zj7gfzigzhavnlbw4et4pvtze

4099Cardiovascular magnetic resonance imaging in cardiac device carriers: assessment of right-ventricular function and scar

S. Loebe, S. Hilbert, A. Weber, C. Rogge, S. Oebel, R. Spampinato, S. Richter, M. Doering, P. Sommer, G. Hindricks, I. Paetsch, C. Jahnke
2017 European Heart Journal  
Whether the increased rate of left ventricular clefts in WD is due to specific pathogenic gene variants remains unclear and will be investigated soon. | BEDSIDE Congenital hypertrophic cardiomyopathy with  ...  Conclusion: Cardiac manifestation of WD seems possible. CMR is capable of revealing subclinical pathological findings. Cardiac involvement as fibrosis may affect prognosis in WD.  ...  Purpose: We aimed to provide data on image quality and feasibility of functional assessment of the right ventricle (RV) depending on the device type and imaging sequence used.  ... 
doi:10.1093/eurheartj/ehx504.4099 fatcat:rphcw6rhwbghtfdd6awmmxzpdy

Guidelines for reporting histopathology studies

N Knijn, I D Nagtegaal
2014 Journal of Clinical Pathology  
In such meta-analyses, only research data of sufficient quality should be used. Universally accepted criteria for the assessment of data quality do not exist.  ...  This limits the quality of the evidence provided in such a paper.  ...  In such meta-analyses, only research data of sufficient quality should be used. Universally accepted criteria for the assessment of data quality do not exist.  ... 
doi:10.1136/jclinpath-2014-202647 pmid:25260356 fatcat:effdiy7qw5ei7jaarhgsi2i7vi

Recommendations for reporting histopathology studies: a proposal

N. Knijn, F. Simmer, I. D. Nagtegaal
2015 Virchows Archiv  
In such meta-analyses, only research data of sufficient quality should be used. Universally accepted criteria for the assessment of data quality do not exist.  ...  This limits the quality of the evidence provided in such a paper.  ...  In such meta-analyses, only research data of sufficient quality should be used. Universally accepted criteria for the assessment of data quality do not exist.  ... 
doi:10.1007/s00428-015-1762-3 pmid:25846513 pmcid:PMC4460276 fatcat:zmhf5hbb45bnhgzowdmgfdcyzu

Image Quality Optimization of Dental Panoramic Tomogram and Lateral Cephalogram: A Pilot Study on Human Skull

L Ghazali, MYP Mohd Yusof, NH Norman
2021 Compendium of Oral Science  
The correlations between radiation doses and diagnostic value of the images were analyzed using Pearson's Correlation Test. Univariate analysis was calculated for the evaluation for image quality.  ...  Purpose: The purpose of this study was to investigate the effects of varying scanning parameters of DPT and LC on diagnostic performance and quality of the images.  ...  Univariate analysis was performed for the image quality assessment and reported as median and inter-quartile range (IQR).  ... 
doi:10.24191/cos.v8i0.17482 fatcat:ehly5zi6u5ap5k45bp75fx2tsa
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