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UniProt: the Universal Protein knowledgebase

R. Apweiler
2004 Nucleic Acids Research  
ACKNOWLEDGEMENTS UniProt is supported mainly by the National Institutes of Health (NIH) grant 1 U01 HG02712-01.  ...  Minor support for the EBI's involvement in UniProt comes from the two European Union contracts BioBabel (QLRT-2000-00981) and TEMBLOR (QLRI-2001-00015) and from the NIH grant 1R01HGO2273-01.  ...  THE UNIPROT KNOWLEDGEBASE (UNIPROT) The UniProt knowledgebase is the centrepiece of the consortium activities.  ... 
doi:10.1093/nar/gkh131 pmid:14681372 pmcid:PMC308865 fatcat:q6fuc2kgujar5drblzqtcbvpou

UniProt: the universal protein knowledgebase

2016 Nucleic Acids Research  
The UniProt knowledgebase is a large resource of protein sequences and associated detailed annotation.  ...  The initial run of this pipeline reduced the number of sequences in UniProt by 47 million.  ...  The UniProt Knowledgebase (UniProtKB) is the central resource that combines UniProtKB/Swiss-Prot and UniProtKB/TrEMBL.  ... 
doi:10.1093/nar/gkw1099 pmid:27899622 pmcid:PMC5210571 fatcat:hk7eqzbncray5nfbzsehqikjnm

UniProt: the universal protein knowledgebase in 2021

The UniProt Consortium, Alex Bateman, Maria-Jesus Martin, Sandra Orchard, Michele Magrane, Rahat Agivetova, Shadab Ahmad, Emanuele Alpi, Emily H Bowler-Barnett, Ramona Britto, Borisas Bursteinas, Hema Bye-A-Jee (+122 others)
2020 Nucleic Acids Research  
The aim of the UniProt Knowledgebase is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional information.  ...  UniProt resources are available under a CC-BY (4.0) license via the web at https://www.uniprot.org/.  ...  ACKNOWLEDGEMENTS The UniProt publication has been prepared by Alex Bateman, Maria  ... 
doi:10.1093/nar/gkaa1100 pmid:33237286 pmcid:PMC7778908 fatcat:6rwvp6l5uzb3li4lygf2gny6qq

UniProt archive

R. Leinonen, F. G. Diez, D. Binns, W. Fleischmann, R. Lopez, R. Apweiler
2004 Bioinformatics  
UniProt Archive (UniParc) is the most comprehensive, non-redundant protein sequence database available. Its protein sequences are retrieved from predominant, publicly accessible resources.  ...  When proteins are loaded into the database, database cross-references are created to link them to the origins of the sequences.  ...  INTRODUCTION Universal Protein Knowledgebase (UniProt) is a central database of protein sequences and functions created by joining the information in SWISS-PROT (Boeckmann et al., 2003) , TrEMBL (Boeckmann  ... 
doi:10.1093/bioinformatics/bth191 pmid:15044231 fatcat:iz22xro7efb33aadhqfagnpigm

The Universal Protein Resource (UniProt)

A. Bairoch
2004 Nucleic Acids Research  
UniProt/Swiss-Prot activities at the SIB are supported by the Swiss Federal Government through the Federal Office of Education and Science.  ...  ACKNOWLEDGEMENTS UniProt is mainly supported by the National Institutes of Health (NIH) grant 1 U01 HG02712-01.  ...  THE UniProt KNOWLEDGEBASE The UniProt Knowledgebase merges Swiss-Prot, TrEMBL and PIR-PSD to provide a central database of protein sequences with annotations and functional information.  ... 
doi:10.1093/nar/gki070 pmid:15608167 pmcid:PMC540024 fatcat:iqjosikdt5epfo6inmhb5uuiyy

UniProt Protein Knowledgebase [chapter]

Sangya Pundir, Maria J. Martin, Claire O'Donovan
2017 Msphere  
The Universal Protein Resource (UniProt) is a freely available comprehensive resource for protein sequence and annotation data.  ...  UniProt is a collaboration between the European Bioinformatics Institute (EMBL-EBI), the Swiss Institute of Bioinformatics (SIB), and the Protein Information Resource (PIR).  ...  Acknowledgments This work was supported by grant U41HG007822 from the National Institutes of Health.  ... 
doi:10.1007/978-1-4939-6783-4_2 pmid:28150232 pmcid:PMC5565770 fatcat:sem3wywevbcancpfdfx3lvpqse

Worm Annotation in the UniProt Knowledgebase (UniProtKB)

Duncan Legge, Duncan Legge, UniProt Consortium
2009 Nature Precedings  
European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK 2 Swiss Institute of Bioinformatics, Geneva, Switzerland 3 Protein Information Resource, Georgetown University, Washington  ...  DC, USA Duncan Legge 1 and UniProt Consortium 1,2,3 Nature Precedings : doi:10.1038/npre.2009.3157.1 : Posted 23 Apr 2009  ... 
doi:10.1038/npre.2009.3157.1 fatcat:rylqgg5kung53j7kwdtd66leii

Worm Annotation in the UniProt Knowledgebase (UniProtKB)

Duncan Legge, Duncan Legge, UniProt Consortium
2009 Nature Precedings  
European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK 2 Swiss Institute of Bioinformatics, Geneva, Switzerland 3 Protein Information Resource, Georgetown University, Washington  ...  DC, USA Duncan Legge 1 and UniProt Consortium 1,2,3 Nature Precedings : doi:10.1038/npre.2009.3157.1 : Posted 23 Apr 2009  ... 
doi:10.1038/npre.2009.3157 fatcat:davx5x6clvbr5gp4uifr2w4lki

Xenopus and Zebrafish Annotation in the UniProt Knowledgebase (UniProtKB)

Rebecca Foulger, UniProt Consortium
2009 Nature Precedings  
Protein Information Resource (PIR) • Xenopus laevis (African clawed frog) and Danio rerio (zebrafish) are both model organisms in the laboratory, as they are easy to accommodate and can produce large numbers  ...  the zebrafish genome in 2001.The extensive similarity between the zebrafish and human genomes means many human developmental and disease genes have counterparts in the zebrafish.  ...  Introduction to UniProtUniProt (Universal Protein Resource: http://www.uniprot.org) provides a central resource of protein sequences with functional annotation.  ... 
doi:10.1038/npre.2009.3153.1 fatcat:d36olesojzc2lht2c3thuocte4

The Universal Protein Resource (UniProt)

2007 Nucleic Acids Research  
The Universal Protein Resource (UniProt) provides a stable, comprehensive, freely accessible, central resource on protein sequences and functional annotation.  ...  UniProt is comprised of four major components, each optimized for different uses: the UniProt Knowledgebase, the UniProt Reference Clusters, the UniProt Archive and the UniProt Metagenomic and Environmental  ...  ACKNOWLEDGEMENTS UniProt is mainly supported by the National Institutes of Health (NIH) grant 2 U01 HG02712-05.  ... 
doi:10.1093/nar/gkl929 pmid:17142230 pmcid:PMC1669721 fatcat:3doko4bysfhmzddimueyp2tj3y

Searching and Navigating UniProt Databases

Sangya Pundir, Michele Magrane, Maria J. Martin, Claire O'Donovan
2015 Current Protocols in Bioinformatics  
The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data.  ...  The key UniProt datasets are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef) and the UniProt Archive (UniParc) and protein sets for completely sequenced genomes (Proteomes  ...  Acknowledgments This work was supported by the National Institutes of Health [U41HG006104, U41HG007822, U41HG002273, R01GM080646, G08LM010720, P20GM103446]; British Heart Foundation [RG/13/5/30112]; Parkinson's  ... 
doi:10.1002/0471250953.bi0127s50 pmid:26088053 pmcid:PMC4522465 fatcat:o2ggn5ojxvaajfkymbfhifi7vi

The Universal Protein Resource (UniProt)

2007 Nucleic Acids Research  
The primary mission of UniProt is to support biological research by maintaining a stable, comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with extensive  ...  cross-references and querying interfaces freely accessible to the scientific community.  ...  THE UNIPROT DATABASES The UniProt Knowledgebase (UniProtKB) UniProtKB consists of two sections, UniProtKB/Swiss-Prot and UniProtKB/TrEMBL.  ... 
doi:10.1093/nar/gkm895 pmid:18045787 pmcid:PMC2238893 fatcat:pbq7vsuwtfafzco3f5dcfipvba

A Guide to UniProt for Protein Scientists [chapter]

Claire O'Donovan, Rolf Apweiler
2010 Msphere  
The scope of this chapter is to illustrate how Universal Protein Resource (UniProt) (The UniProt Consortium, Nucleic Acids Res. 38:D142-D148, 2010) can be best utilized for proteomics purposes with a particular  ...  focus on exploiting the knowledge captured in the UniProt databases, the services provided and the availability of complete proteomes.  ...  In this chapter, we will show how the Universal Protein Resource fulfils these criteria.  ... 
doi:10.1007/978-1-60761-977-2_2 pmid:21082425 fatcat:a547fe36zfeq3f4csfvnrtjog4

The Universal Protein Resource (UniProt) 2009

2009 Nucleic Acids Research  
The UniProt Knowledgebase (UniProtKB) is an expertly curated database, a central access point for integrated protein information with cross-references to multiple sources.  ...  The UniProt Reference Clusters (UniRef) UniRef provides clustered sets of all sequences from the UniProt Knowledgebase (including splice forms as separate entries) and selected UniProt Archive records  ... 
doi:10.1093/nar/gkn664 pmid:18836194 pmcid:PMC2686606 fatcat:4nz73vlhq5f7fbcyreyxbtse6a

The Universal Protein Resource (UniProt) in 2010

2009 Nucleic Acids Research  
The primary mission of UniProt is to support biological research by maintaining a stable, comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with extensive  ...  cross-references and querying interfaces freely accessible to the scientific community.  ...  Additional support for the EBI's involvement in UniProt comes from the European Commission contract SLING grant  ... 
doi:10.1093/nar/gkp846 pmid:19843607 pmcid:PMC2808944 fatcat:zzpkffi7h5aipaogu36t35y77q
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