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Ultra-high resolution brain metabolite mapping at 7 T by short-TR Hadamard-encoded FID-MRSI

Gilbert Hangel, Bernhard Strasser, Michal Považan, Eva Heckova, Lukas Hingerl, Roland Boubela, Stephan Gruber, Siegfried Trattnig, Wolfgang Bogner
2018 NeuroImage  
Keywords: Proton magnetic resonance spectroscopic imaging 7 T Ultra-high resolution spectroscopic imaging Parallel imaging Brain Hadamard encoding A B S T R A C T MRSI in the brain at7 T is a technique  ...  To overcome these limitations, we propose an ultra-high resolution (UHR) MRSI sequence that provides a 128×128 matrix with a nominal voxel volume of 1.7×1.7×8 mm 3 in a comparatively short measurement  ...  Purpose We propose a high-resolution FID-acquisition sequence for ultrahigh resolution (UHR)-MRSI at 7 T.  ... 
doi:10.1016/j.neuroimage.2016.10.043 pmid:27825954 fatcat:jltpe5k7azgcta447oyogn5w6a

(2 + 1)D-CAIPIRINHA accelerated MR spectroscopic imaging of the brain at 7T

B. Strasser, M. Považan, G. Hangel, L. Hingerl, M. Chmelik, S. Gruber, S. Trattnig, W. Bogner
2016 Magnetic Resonance in Medicine  
2D-CAIPIRINHA at 7 Tesla (T).  ...  Thus, this sequence significantly decreased the RMSE of the metabolic maps by 12.1 and 6.9%, on average, for 4 < R < 11, compared with 2D-GRAPPA and 2D-CAIPIRINHA, respectively.  ...  ACKNOWLEDGMENTS This study was supported by the Austrian Science Fund (KLI-61) and FFG Bridge Early Stage Grant No. 846505.  ... 
doi:10.1002/mrm.26386 pmid:27548836 pmcid:PMC5535010 fatcat:zcyjyhad25aqhczsi3dc535s7m

In-vivo 31 P-MRS of skeletal muscle and liver: A way for non-invasive assessment of their metabolism

Ladislav Valkovič, Marek Chmelík, Martin Krššák
2017 Analytical Biochemistry  
In addition to direct assessment of high energy phosphorus containing metabolite content within tissues, phosphorus magnetic resonance spectroscopy (31P-MRS) provides options to measure phospholipid metabolites  ...  Acknowledgement The financial support for the research of the authors at their home institutions by the Christian Doppler Society e Clinical Molecular MR Imaging (MOLIMA), by the OeNB Jubilaeumsfond (grant  ...  #15363 and #15455), by the Slovak Grant Agencies VEGA (grant #2/0001/17) and APVV (grant #15-0029), and by a Sir Henry Dale Fellowship from the Wellcome Trust and the Royal Society (grant #098436/Z/12  ... 
doi:10.1016/j.ab.2017.01.018 pmid:28119063 pmcid:PMC5478074 fatcat:5fzgmb2kf5d6znf7xkjhakfhcq

In-Vivo Three Dimensional Proton Hadamard Spectroscopic Imaging in the Human Brain

Ouri Cohen
The benefits of T-HSI are demonstrated by a quantitative comparison to CSI of the SNR and localization in a phantom in both one and three dimensions at clinical resolutions.  ...  Clinical utility of the new method is shown by spectra obtained from the brain of a healthy volunteer.  ...  axial, sagittal and coronal projections at 1 mm 3 isotropic resolution for VOI image-guidance. 3D T-HSI At TR=1.2 s, optimal for ~1 s T 1 s of brain metabolites (83), the 8×8×4=256 encoding steps  ... 
doi:10.7916/d8639x3v fatcat:3h7awooaqzglbcbaxqo6rqhrbi

Developing a fully scanner-integrated reconstruction pipeline for Magnetic Resonance Spectroscopic Imaging (MRSI)

Jan Luxemburg, Gerald Badurek
To support the research group in the High-Field MR Centre in Vienna at the AKH and the Medical University, a fully scanner-integrated reconstruction pipeline for a fast whole-brain Magnetic Resonance Spectroscopic  ...  Imaging (MRSI) sequence was developed.  ...  Subsequently, the VAPOR technique was also adapted for human brain applications at 7 T.  ... 
doi:10.34726/hss.2022.87801 fatcat:m2c6mys555ganmvynjy6xmxq3m

Functional 1H MR spectroscopic investigations of pain processing in the human brain [article]

Marianne Cleve, Universitäts- Und Landesbibliothek Sachsen-Anhalt, Martin-Luther Universität, Jochen Balbach, Jürgen R. Reichenbach, Peter Bachert
Proton magnetic resonance spectroscopy (1H MRS) enables quantitation of brain metabolites in vivo and non-invasively.  ...  The regulation of signal transduction in the human brain by the main inhibitory and excitatory neurotransmitters GABA and glutamate is subject of current research, as alterations in their turnover are  ...  Exemplary statistical parametric maps are mapped onto a transverse anatomical high resolution MP-RAGE scan. The color encodes the statistical power of the activation patterns.  ... 
doi:10.25673/2160 fatcat:nulz4hjt6nctvakbmwkblr6euu