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Green Tea Catechins Improve Human Forearm Vascular Function and Have Potent Anti-Inflammatory and Anti-Apoptotic Effects in Smokers

Jun-ichi Oyama, Toyoki Maeda, Makoto Sasaki, Kazuya Kozuma, Ryuji Ochiai, Ichiro Tokimitsu, Sachiyo Taguchi, Yoshihiro Higuchi, Naoki Makino
2010 Internal medicine (Tokyo. 1992)  
Objective Several epidemiological investigations have reported that green tea reduces cardiovascular and cerebral vascular risks. Green tea catechins may improve peripheral endothelial dysfunction in smokers. The purpose of this study was to elucidate the beneficial effect of green tea catechins on the repair of endothelial dysfunction in smokers. Methods Thirty healthy male smokers divided into three groups ingested a green tea beverage containing 0 mg (control group), 80 mg (middle dose
more » ... or 580 mg (high dose group) of green tea catechins (GTC) daily for two weeks, and endothelial-dependent vasodilatation was investigated by measuring forearm blood flow (FBF) response to reactive hyperemia (RH) by venous occlusion strain-gauge plethysmography. Results An acute effect was that the FBF response to RH significantly increased 2 hr after GTC intake in the high dose group. However, no increase was observed in the other groups. The chronic administration of GTC for one or two weeks ameliorated the FBF responses to RH in the high dose group. On the other hand, no significant increase was observed in the FBF responses to RH in the other groups. Moreover, the plasma concentration of 8-OHdG, IL-6, TNF-alpha, and soluble Fas decreased significantly for two weeks in the high dose group, however, the level of IL-1 beta remained unchanged over this period. Conclusion Green tea consumption over short and long periods appears to ameliorate endothelial dysfunction by scavenging free radicals with anti-inflammatory and anti-apoptotic properties in healthy male smokers.
doi:10.2169/internalmedicine.49.4048 pmid:21139292 fatcat:73xgnmjfffekrhbfi7ff3orxzu

Effects of Planting Density and Air Current Speed on the Growth and That Uniformity of Tomato Plug Seedlings in a Closed Transplant Production System

Shingo YOKOI, Eiji GOTO, Toyoki KOZAI, Masao NISHIMURA, Katsunori TAGUCHI, Yasuhiro ISHIGAMI
2007 Shokubutsu Kankyo Kogaku  
doi:10.2525/shita.19.159 fatcat:rytuqbis2bft3dttbxjvod2lta

Effects of Planting Density and Air Current Speed on the Growth and Uniformity of Qing-geng-cai and Spinach Plug Seedlings in a Closed Transplant Production System

Shingo YOKOI, Eiji GOTO, Toyoki KOZAI, Masao NISHIMURA, Katsunori TAGUCHI, Yasuhiro ISHIGAMI
2008 Environment Control in Biology  
doi:10.2525/ecb.46.103 fatcat:o5dyu6k5w5adhdznqzatj2l2pa

Solar Neutron and Gamma-ray Monitor on the ChubuSat-2 Satellite

Kazutaka YAMAOKA, Yasunobu BABAZAKI, Yuki HAYASHI, Hidehiro KANEDA, Taishi KATSURAGAWA, Hiroaki KAWAHARA, Takuma KOKUSHO, Shin KUBO, Kazunari MATSUNAGA, Koji MATSUSHITA, Kikuko MIYATA, Takuya MIYAZAWA (+14 others)
The ChubuSat is a Japanese microsatellite technology demonstration mission jointly depeloped by Nagoya university, Daido university, and medium or small-sized aerospace industrial companies in the Chubu area of central Japan. ChubuSat-2 is the second ChubuSat following ChubuSat-1 which was launched by the Russian DNEPR rocket on November 6, 2014. It was selected as one of the four piggyback payloads of the X-ray astronomy satellite ASTRO-H in 2014 summer, and will be launched by the H-IIA
more » ... from Japan Aerospace Exploration Agency (JAXA) Tanegashima Space Center (TNSC) in winter season of fiscal year (FY) 2015. The ChubuSat-2 mission is devoted to monitoring neutrons and gamma-rays in the ASTRO-H orbit which can be noise sources for ASTRO-H X-ray and soft gamma-ray observations. The mission involves solar neutron observations which were originally proposed by graduate students who joined the leadership development program for space exploration and research, a program for leading graduate schools at Nagoya University. In this paper, we describe the outline of the ChubuSat-2 satellite and the details of the mission instrument, the radiation detector (RD).
doi:10.2322/tastj.14.pf_141 fatcat:nwoyk6aepjac7i35ep7vgt7yay


2012 Circulation Journal  
, Haruyuki 2748 Taguchi, Hiroki 1245, 1494 Taguchi, Isao 1326 Tahara, Nobuhiro 2742 Tahara, Yoshio 2579 Tahk, Seung-Jae 405 Tajik, A.  ...  Hirata, Yumi 2096 Hiratsuka, Atsushi 624 Hirayama, Atsushi 322, 825, 1197 Hirayama, Haruo 2280 Hiro, Takafumi 825, 2840 Hirooka, Yoshitaka 2814 Hirose, Masahiro 2647 Hirose, Takeshi 2755 Hirose, Toyoki  ... 
doi:10.1253/circj.cj-76-12-index_2 fatcat:gccqbrs5jfb77boi4bvh2wtoj4


2009 Circulation Journal  
, Hiroshi 963 MacIver, David H 1169 Madias, John E 593 Maeda, Keiko 1836 Maeda, Kouji 772 Maeda, Kumiko 1092 Maeda, Minetaka 2355 Maeda, Ryo 549 Maeda, Shingo 2223 Maeda, Tomoko 1864 Maeda, Toyoki  ...  , Haruyuki 1092 Taguchi, Isao 1466 Tagusari, Osamu 2056 Tahara, Shoichi 2125 Tajima, Akihiko 1864 Tajima, Hiroyuki 106 Takada, Shiho 179 Takada, Shingo 534 Takagi, Masahiko 1836 Takagi, Yusuke  ... 
doi:10.1253/circj.index12_2 fatcat:rm6ryep7pjg5tf5rcdjgwolkku

日本内分泌学会分科会抄録集 第10回日本ステロイドホルモン学会

2002 Folia Endocrinologica Japonica  
Prevention and Therapy 13:30-14:50 (Room 5) P3-55 "Sex steroid dpendent angiogenesis and tumor dormancy therapy in uterine endometrial cancers" Jiro Fujimoto, Ikumi Aoki, Hiroshi Toyoki  ...  Hajime Nawata (Japan) P3-09 "Activation of peroxisome proliferator-activated receptor-gamma stimulates the growth arrest and DNA-damage Inducible 153 gene in non-small cell lung carcinoma cells" Mayuko Taguchi  ... 
doi:10.1507/endocrine1927.78.2_332 fatcat:c7fcuj4oizdrjhxb4nfp56gkrq

Green Tea Catechins Improve Human Forearm Endothelial Dysfunction and Have Antiatherosclerotic Effects in Smokers

Jun-ichi Oyama, Toyoki Maeda, Kazuya Kouzuma, Ryuji Ochiai, Ichiro Tokimitsu, Yoshihiro Higuchi, Masahiro Sugano, Naoki Makino
2010 Circulation Journal  
Acknowledgments The authors thank Sachiyo Taguchi for her important contributions during the study.  ... 
doi:10.1253/circj.cj-09-0692 pmid:20134098 fatcat:7ybwomq2l5hwznplrw3h5uccnu

Enchi Fumiko : an examination of political aspects in Enchi Fumiko's works [article]

Kaori Katagiri, University Of Canterbury
regard Toyoki as inhuman.  ...  This allowed a politician, Taguchi Ukichi, to advocate the irrational theory that "the Japanese elite class is originally white." 169 In the Meiji period, the Japanese adopted Herbert Spencer's theory  ... 
doi:10.26021/3839 fatcat:mq4xn3lnk5dbbf5elk54w5l6by

Antioxidant therapy attenuates myocardial telomerase activity reduction in superoxide dismutase-deficient mice

Naoki Makino, Toyoki Maeda, Jun-ichi Oyama, Makoto Sasaki, Yoshihiro Higuchi, Koji Mimori, Takahiko Shimizu
2011 Journal of Molecular and Cellular Cardiology  
Taguchi, and Ms. Y. Ueda for their expert technical assistance. This work was supported in part by a Grant-in-Aid from the Ministry of Education, Science, and Culture of Japan.  ... 
doi:10.1016/j.yjmcc.2010.12.014 pmid:21195081 fatcat:yyr5f5lwpjfzxkkn2agi6jsqwa

Supplemental Upward Lighting from Underneath to Obtain Higher Marketable Lettuce (Lactuca sativa) Leaf Fresh Weight by Retarding Senescence of Outer Leaves

Geng Zhang, Shanqi Shen, Michiko Takagaki, Toyoki Kozai, Wataru Yamori
2015 Frontiers in Plant Science  
., 2001; Taguchi, 2003) . The white LEDs used in the present study combined a blue LED with a yellow phosphor (Supplementary Figure S1A) .  ... 
doi:10.3389/fpls.2015.01110 pmid:26697055 pmcid:PMC4677251 fatcat:5ub7byssofgabfxdv4xkizftqq

Age-Related Changes in Subtelomeric Methylation in the Normal Japanese Population

T. Maeda, J. Z. Guan, J.-i. Oyama, Y. Higuchi, N. Makino
2009 The journals of gerontology. Series A, Biological sciences and medical sciences  
Acknowledgments We thank Ms Ueda and Ms Taguchi for their valuable technical assistance. We are grateful to Mr Brian Quinn for his linguistic advice.  ...  Correspondence Address correspondence to Toyoki Maeda, MD, PhD, Division of Molecular and Clinical Gerontology, Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu  ... 
doi:10.1093/gerona/gln057 pmid:19223605 pmcid:PMC2657167 fatcat:hfmbvmzbeva2pnyk2jj5ma3g4e

Repetitive hyperthermia attenuates progression of left ventricular hypertrophy and increases telomerase activity in hypertensive rats

Jun-ichi Oyama, Toyoki Maeda, Makoto Sasaki, Yoshihiro Higuchi, Koichi Node, Naoki Makino
2012 American Journal of Physiology. Heart and Circulatory Physiology  
ACKNOWLEDGMENTS The authors thank Keiko Tsuchida, Sachiyo Taguchi, and Yasuko Ueda for expert technical assistance. GRANTS  ... 
doi:10.1152/ajpheart.00225.2011 pmid:22427516 fatcat:5crpk4hp75ax5dlcu2l6ncdpaq

Improving insulin sensitivity via activation of PPAR-γ increases telomerase activity in the heart of OLETF rats

Naoki Makino, Toyoki Maeda, Jun-ichi Oyama, Yosihiro Higuchi, Koji Mimori
2009 American Journal of Physiology. Heart and Circulatory Physiology  
Taguchi, and Y. Ueda for the expert technical assistance. GRANTS  ... 
doi:10.1152/ajpheart.00421.2009 pmid:19855065 fatcat:er5kn3msxzgv3l6ldh42k4o5n4

Page 1080 of Index to Dental Literature Vol. , Issue [page]

Index to Dental Literature  
ORL J Otorhinolaryngol Relat Spec 1994 May-Jun; 56(3):133-6 M, Taguchi K, Ishiyama T: Acute pharyngitis, an unusual complication of intravenous hyperalimentation.  ...  Neurosci Lett 1994 Jan 31;166(2):143-8 Saha V see Attard-Montalto SP Sahara N, Okafuji N, Toyoki A, et al: Odontoclastic resorption of the superficial nonmineralized layer of predentine in the shedding  ... 
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