A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2022; you can also visit the original URL.
The file type is application/pdf.
Filters
Sodium Thiosulfate acts as an H2S mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerization
[article]
2021
bioRxiv
pre-print
Preserved Fulltext
Interpretation: STS, a drug used for the treatment of cyanide poisoning and calciphylaxis, protects against IH in a mouse model of arterial restenosis and in human vein segments. ...
Intimal hyperplasia (IH) remains a major limitation in the long-term success of any type of revascularization. ...
Right panel Quantitative assessment of Collagen III immunofluorescent staining. Data are scatter plots of 5 different veins with mean±SEM. ...
doi:10.1101/2021.09.09.459573
fatcat:c6nhg3c6ireezp7vxjgndcuari
An antioxidant approach directed to non-healing wounds activation - A case report study
2021
Clinical Case Reports and Reviews
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Conflicts of interest: The authors declare no conflict of interest. ...
The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results. ...
This method allows the simultaneous assessment of key parameters that indicate the progression towards healing. ...
doi:10.15761/ccrr.1000499
fatcat:nfd3qxmfmna5fjmcwalraqnt6q
The Strategy to Prevent and Regress the Vascular Calcification in Dialysis Patients
2017
BioMed Research International
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
, intravenous labile iron, and positive calcium and phosphate balance), correction of high and low bone turnover, and restoration of anticalcification factor balance such as correction of vitamin D and ...
The role of bone antiresorption therapy such as bisphosphonates and denosumab in vascular calcification in high-bone-turnover disease remains unclear. ...
Despite its weaknesses as a biomarker, PTH represents perhaps the best current option for noninvasive assessment of bone turnover. ...
doi:10.1155/2017/9035193
pmid:28286773
pmcid:PMC5329685
fatcat:aem7bwdwxvdpbh5e65hlkp3jjy
Longitudinal changes in bone and mineral metabolism after cessation of cinacalcet in dialysis patients with secondary hyperparathyroidism
2018
BMC Nephrology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Over the 12-month period, there were two fractures, five cardiovascular events, one episode of calciphylaxis, and one parathyroidectomy, with a mortality rate of 19% (n = 13). ...
Changes to reimbursement of cinacalcet in Australia provided an opportunity to assess effects of medication cessation on biochemical and clinical outcomes in dialysis patients, including changes to novel ...
Acknowledgements The authors acknowledge the help of Connie Karschimkus in collecting study samples over the trial period. ...
doi:10.1186/s12882-018-0910-9
pmid:29764395
pmcid:PMC5952622
fatcat:c2pc2vljrffrzbbq3i33wd7nya
An approach to the diagnosis and treatment of cryofibrinogenemia
2004
American Journal of Medicine
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf.
Diagnostic criteria are outlined, and therapies are assessed critically. This information should help clinicians in establishing a diagnosis of cryofibrinogenemia and initiating treatment. ...
In this review, the classification, pathophysiology, and clinical presentation of cryofibrinogenemia are described, based on case reports and prospective observational data. ...
Cryofibrinogens can be quantitated in two ways. ...
doi:10.1016/j.amjmed.2003.09.033
pmid:14984819
fatcat:wfxbr7hf45dcnkkc3s4uyx3pq4
Cardiovascular Pathology
2017
Modern Pathology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
AR expression in TNBCs using 1% and 10% cutoff was 41% and 28% respectively of all TNBCs. CK5/6 expression was seen in 122 of 228 (54%), 106 of 228 (46%) TNBCs. ...
The percentage and intensity of both markers were evaluated by two pathologists independently. ...
None of the amputation patients had a clinical presentation suggestive of calciphylaxis. ...
doi:10.1038/modpathol.2016.244
pmid:28134891
fatcat:5mssizt6orb57m2w4yr6xx5ywq
Dermatopathology
2016
Laboratory Investigation
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
diagnosis of calciphylaxis. ...
Fetuin-B staining was positive in 63% (5/8) of calciphylaxis cases and 33% (5/15) of non-calciphylaxis cases (p=0.17). ...
doi:10.1038/labinvest.2016.6
pmid:26813168
fatcat:bam5xm6jjbe3bn2kgxtzrgy5vq
Vascular calcification in chronic kidney disease: Pathogenesis and clinical implication
2012
World Journal of Nephrology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
of calcification inhibitors play important roles in promoting the development of VC. ...
risk factors on the development of VC. ...
As a result, the possibility of accurate assessment of changes of calcification burden, especially over a short period of time, may be limited. ...
doi:10.5527/wjn.v1.i2.43
pmid:24175241
pmcid:PMC3782198
fatcat:depkyihfdzherjbwcrpgguuuo4
Osteogenic regulation of vascular calcification: an early perspective
2004
American Journal of Physiology. Endocrinology and Metabolism
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
A minimum of four histoanatomic variants-atherosclerotic (fibrotic) calcification, cardiac valve calcification, medial artery calcification, and vascular calciphylaxis-arise in response to metabolic, mechanical ...
and extent of calcific vasculopathy. ...
However, only intact OPN was assayed (92) , and no quantitative assessment of OPN phosphorylation in vascular or circulating forms induced by PTH has yet been performed. ...
doi:10.1152/ajpendo.00552.2003
pmid:15102615
fatcat:o5l2ahdvlbfw5ihfmf6boswvim
SNF472, a novel inhibitor of vascular calcification, could be administered during hemodialysis to attain potentially therapeutic phytate levels
2018
JN. Journal of Nephrology (Milano. 1992)
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
SNF472 (the hexasodium salt of phytate) is being developed for the treatment of calciphylaxis and CVC in HD patients. ...
Methods Dialyzability was assessed in vitro using online-hemodiafiltration and high-flux HD systems in blood and saline. SNF472 was infused for 20 min and quantified at different time points. ...
Government of Spain) grants. ...
doi:10.1007/s40620-018-0471-9
pmid:29350348
pmcid:PMC5829128
fatcat:idat2zjsmzflbjil2tcsfcrlu4
The Skin as a critical window in unveiling the pathophysiologic principles of COVID-19
2021
Clinics in Dermatology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
In this contribution, we review an array of cutaneous manifestations of COVID-19 that provide an opportunity to study critical pathophysiologic mechanisms that underlie all clinical facets of COVID-19, ...
A variety of skin eruptions have been described in the setting of SARS-CoV-2 infection and more recently, after COVID-19 vaccination. ...
classic features of calciphylaxis. ...
doi:10.1016/j.clindermatol.2021.07.001
pmid:34920833
pmcid:PMC8298003
fatcat:kfmnrezvibcobctj5bjm3aqvja
Cilostazol attenuates intimal hyperplasia in a mouse model of chronic kidney disease
2017
PLoS ONE
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
We demonstrated a proof of concept of the effectiveness of cilostazol in attenuating IH in a Chr I/R mouse model, a CKD model with predominantly indirect-vascular-injury-induced IH. ...
The diameters of aorta and renal function were unchanged by cilostazol. ...
Histology and assessment of intimal hyperplasia The vascular cross-sections of aorta (3 μm thickness) were stained with H&E and PAS, then quantitatively analyzed in ten sections per mouse, starting from ...
doi:10.1371/journal.pone.0187872
pmid:29206849
pmcid:PMC5716535
fatcat:5tziypri75funa3qzlmcolndiy
Poster Presentations
2021
Nephrology (Carlton. Print)
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2022; you can also visit the original URL.
The file type is application/pdf.
Methods and Material: A case of rhabdomyolysis-associated AKI in the setting of statin therapy is described here. ...
Objectives: A case of statin-induced rhabdomyolysis is presented here, highlighting the pathophysiology and complications of this condition. ...
This study is supported by National Research Council of Thailand (6/2562). ...
doi:10.1111/nep.13944
fatcat:2rir6wey7vgrzlqzilykfpnw2i
Bisphosphonates in Chronic Kidney Disease; Balancing Potential Benefits and Adverse Effects on Bone and Soft Tissue
2009
American Society of Nephrology. Clinical Journal
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2009; you can also visit the original URL.
The file type is application/pdf.
The authors review the potential benefits and risks associated with bisphosphonate use for bone protection in CKD, and assess their effect on vascular calcification and atherosclerosis. ...
Some experimental and clinical studies have also suggested that bisphosphonates may reduce progression of extra-osseous calcification and inhibit the development of atherosclerosis. ...
sensitivity or specificity except toward the extremes. ...
doi:10.2215/cjn.02550508
pmid:18987295
fatcat:xoblvea3sfactnur5upcqqubgu
Calcification of Aortic Smooth Muscle Cells Isolated From Spontaneously Hypertensive Rats
2008
Journal of Pharmacological Sciences
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
The gene expressions of calcificationregulating proteins including msh homeobox homolog 2, Osterix (a master transcription factor for osteogenesis), and alkaline phosphatase (ALP) (a marker of vascular ...
normotensive rats and spontaneously hypertensive rats (SHR), a typical rat model of hypertension. ...
Acknowledgments This work was supported in part by a Grant-in-Aid from the Ministry of Education, Science, Sports, and Culture of Japan to Dr. Ken-Ichi Furukawa. Financial support to Dr. ...
doi:10.1254/jphs.fp0072013
pmid:18270471
fatcat:vhafp24blfclblkolpwcbgvulq
« Previous
Showing results 1 — 15 out of 120 results