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Yamamura and H. Banda H 1 B r.i2 1 B .:12 ·2 B 0 r.i • vib=-f i t -' + -71-' r + f! ... Yamamura and H. Bando In this case it can be easily verified that Eq. (4·5) becomes Equation ( 4 ·16) is nothing but another expression for Eq. ( 4 · 9). ...doi:10.1143/ptp.28.87 fatcat:yutih37vwzbehpdf3owxpml2oq
Case 1 A 74-year-old woman with a history of diabetes mellitus controlled with oral medication was admitted to our Abstract The authors report two cases of hypoglycemic coma in which both diffusion-weighted imaging (DWI) and single photon emission computed tomography (SPECT) were used. A 74-year-old woman (case 1) presented with deep coma associated with hypoglycemia (blood glucose level: 20 mg/dl), and DWI on admission revealed extensive hyperintensity lesions. SPECT obtained on the seconddoi:10.4103/0028-3886.48814 pmid:19305083 fatcat:zjdlcjd7qjdtlbrlvxndtwtj7q
more »... ital day revealed diffuse hyperperfusion and a follow-up SPECT on the eighth hospital day showed relative hypoperfusion. An 89-year-old woman (case 2) presented with coma associated with hypoglycemia (blood glucose level: 45 mg/dl), and DWI showed diffuse hyperintensity lesions in both hemispheres. SPECT obtained on the ninth hospital day showed relative hypoperfusion compared to the first scan obtained on the third hospital day. Although the blood glucose level was rapidly corrected, the level of consciousness remained unchanged in both cases. Our results suggest that cerebral blood flow may increase even after glucose correction and that relative hypoperfusion could occur in the subacute stage of hypoglycemic coma.
Cyclamen persicum is one of the most important pot plants in the world. We developed an effective method for somatic embryo-mediated plant regeneration and genetic transformation using Agrobacterium, with somatic embryos as the source of plant material. Numerous somatic embryos were formed from the leaf segments of Cyclamen cv. "Fragrance Mini" 16 weeks after initiation on a 2,4-D-and kinetin-containing medium. The maximum regeneration frequency from the somatic embryos was achieved using adoi:10.5511/plantbiotechnology.25.77 fatcat:7iqruoowyjfjbau3bt7qu22aoy
more »... neration medium containing 0.1 mg l Ϫ1 benzylaminopurine, 0.01 mg l Ϫ1 a-naphthaleneacetic acid, and 0.2 mg l Ϫ1 gibberellin. After co-cultivating the somatic embryos with Agrobacterium strain LBA4404 (the plasmid vector pIG121Hm) that harbors genes for hygromycin phosphotransferase, neomycin phosphotransferase, and b-glucuronidase, hygromycin-resistant clones were selected on a medium containing 5 mg l Ϫ1 hygromycin. Hygromycin-resistant plantlets were regenerated from 14 hygromycin-resistant embryos. Using this transformation system, 74 independent plants were obtained from 1-ml packed cell volume, approximately 2,000 embryos.
Cathepsin K is a recently identified cysteine protease which is abundantly and selectively expressed in osteoclasts. To evaluate the contribution of cathepsin K to bone resorption processes, we investigated the effect of cathepsin K antisense phosphothiorate oligodeoxynucleotide (S-ODN) on the bone-resorbing activity of osteoclasts. Rabbit osteoclasts were cultured on dentine slices for 24 h in the presence or absence of antisense S-ODN in a medium containing 100 nM Tfx TM -50, polycationicdoi:10.1074/jbc.272.13.8109 pmid:9079619 fatcat:ykozucfmu5dnhk6ssf6tkfg7za
more »... some, as a carrier of the S-ODN. Uptake of the S-ODN by osteoclasts was confirmed microscopically using fluorescein-labeled S-ODN. The treatment with antisense significantly decreased the amount of cathepsin K protein in osteoclasts. The antisense inhibited the osteoclastic pit formation in a concentration-dependent fashion. At 10 M the antisense reduced the total pit number and area and average pit depth by 46, 52, and 30%, respectively. The sense and mismatch S-ODNs, which were used as negative controls, had no effect on either the cathepsin K protein level or the pit formation. A nonspecific cysteine protease inhibitor, E-64, also reduced pit formation in a concentration-dependent manner with maximum reductions at 1 M of 46, 48, and 35% in the above pit parameters. The inhibitory effect of the antisense almost equal to that of E-64 demonstrates that cathepsin K is a cysteine protease playing a crucial role in osteoclastic bone resorption.
Yukako Tanaka, 1 Manabu Nonaka, 1 * Yukie Yamamura, 1 Etsuko Tagaya, 2 Ruby Pawankar, 3 Toshio Yoshihara 1 Department of Otolaryngology, 1 First Department of Medicine, 2 Tokyo Women's Medical University ...doi:10.4168/aair.2013.5.3.175 pmid:23638317 pmcid:PMC3636453 fatcat:wx7a5h2kyrhsllntnyaw5yi75y
Yamamura and A. ...doi:10.1143/ptp.31.1009 fatcat:wiylvexnxzdt5mlocinnvmseue
YAMAMURA : Basal Cell Carcinoma Originating in the Lacrimal Sac Fig. 6 a. The tumor consisting of variably sized and shaped nests of basoloid cells. (H & E ; •~70). b . ...doi:10.5106/jjshns.13.29 fatcat:dkpjpoo5kbdrlnvtvzrg5szbly
The dielectric properties of Ca-stabilized ZrO 2 (Zr 0.9 Ca 0.1 O 2-δ , 10CSZ) which is an oxide ion conductor were investigated. Numerical analyses for the frequency dependence of dielectric constant (ε r ′) and dielectric loss factors (ε r ″) revealed that the dielectric properties were made up of Debye-type polarization due to dopant-vacancy associates [Ca zr ″-V o¨] and interfacial polarization at electrolyte-electrode. Two Debye-type relaxations were observed. This result implies thedoi:10.14723/tmrsj.34.237 fatcat:jpsiibhs6rgjvg6ht5aeyridgi
more »... nce of two dopant-vacancy associates with different distances. Moreover, by using the dielectric constants obtained from the numerical analysis, the frequency dependences of ac conductivity (σ ac ) and dielectric loss tangent (tanδ) were also explained.
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